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All Journal Althea Medical Journal Global Medical and Health Communication Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Jurnal Integrasi Kesehatan dan Sains Jurnal Riset Kedokteran Bandung Conference Series : Medical Science
Ismet Muchtar Nur
Fakultas Kedokteran, Universitas Islam Bandung
Humanities Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Perbandingan Efek Antibakteri Ekstrak Air Kopi Arabika dengan Ekstrak Air Teh Hijau pada Kultur Bakteri Methicillin-resistant Staphylococcus Aureus (MRSA) ATTC 33951 Muhammad Gibran Al Madani; Hendro Sudjono Yuwono; Ismet Muchtar Nur
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.10332

Abstract

Abstract. Arabica coffee and green tea are known as plants that contain active antibacterial compounds such as alkaloids, tannins, phenolic compounds, flavonoids, triterpenoids, and glycosides. Methicillin-resistant Staphylococcus Aureus (MRSA) is a common bacteria that emerges due to methicillin resistance, posing a significant infection problem in both hospitals and the general population. This study aims to analyze the comparative antibacterial strength of Arabica coffee water extract and green tea water extract against MRSA bacteria. This research is a pure in vitro experiment using the Disk Diffusion method on MRSA ATCC 33951 bacterial cultures conducted at the Microbiology Laboratory of the Faculty of Medicine, Universitas Padjadjaran, Bandung. The arabica coffee water extract and green tea water extract used were at concentrations of 50% and 100%, while vancomycin was used as the positive control in this study. The inhibition zones were measured in millimeters. Statistical analysis was performed using the Kruskal-Wallis test at a 95% confidence level. The research results showed that the Arabica coffee water extract at concentrations of 50% and 100% had average inhibition zones of 9,75 mm and 14,25 mm, while the green tea water extract at concentrations of 50% and 100% had average inhibition zones of 22,25 mm and 26 mm. Vancomycin as the positive control had an average inhibition zone of 21,75 mm. The green tea water extract had a larger inhibition zone compared to the Arabica coffee water extract with p = 0,000 (p < 0,05). In conclusion, the green tea water extract has a stronger antibacterial effect compared to the arabica coffee water extract. Abstrak. Kopi arabika dan teh hijau dikenal sebagai tanaman yang memiliki kandungan zat aktif yang bersifat antibakteri seperti alkaloid, tanin, senyawa fenolik, flavonoid, triterpenoid, dan glikosida,. Bakteri yang sering muncul akibat resistensi methicillin adalah Methicillin-resistant Staphylococcus Aureus (MRSA) yang menjadi masalah infeksi di rumah sakit dan masyarakat umum. Penelitian ini bertujuan untuk menganalisis perbandingan kekuatan antibakteri ekstrak air kopi arabika dan ekstrak air teh hijau terhadap bakteri MRSA. Penelitian ini merupakan eksperimen murni in vitro dengan metode Disk Diffusion pada biakan bakteri MRSA ATCC 33951 yang dilakukan di Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Padjadjaran, Bandung. Ekstrak air kopi arabika dan teh hijau yang digunakan adalah konsentrasi 50% dan 100%, sedangkan kontrol positif pada penelitian ini menggunan vankomisin. Zona hambat diukur dalam satuan millimeter. Analisis statistik dilakukan dengan menggunakan uji Kruskal-Wallis pada tingkat kepercayaan 95%. Hasil penelitian menunjukkan ekstrak air kopi arabika konsentrasi 50% dan 100% memiliki daya zona hambat rata-rata sebesar 9,75 mm dan 14,25 mm, sedangkan ekstrak air teh hijau pada konsentrasi 50% dan 100% memiliki zona hambat rata-rata sebesar 22,25 mm dan 26 mm. Vankomisin sebagai kontrol positif memiliki zona hambat rata-rata sebesar 21,75 mm. Ekstrak air teh hijau memiliki zona hambat yang lebih besar dari ekstrak air kopi arabika dengan p = 0,000 (p < 0,05). Kesimpulan dari penelitian ini adalah ekstrak air teh hijau lebih memiliki efek antibakteri yang lebih kuat dibandingkan dengan ekstrak air kopi arabika.
Hubungan Antara Kemiskinan dengan Kejadian Anemia Defisiensi Zat Besi pada Ibu Hamil di Kota Bandung Tahun 2015–2020 Nurul Izzati Fauzia; Agung Firmansyah Sumantri; Ismet Muchtar Nur
Bandung Conference Series: Medical Science Vol. 4 No. 1 (2024): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v4i1.12415

Abstract

Abstract. Anemia is a condition where red blood cells do not meet the body's physiological needs, this occurs because the erythrocytes in the body are not balanced. The condition of anemia often occurs in pregnant women, the most common occurrence is iron deficiency anemia and this condition has serious consequences for the mother and fetus. There are several factors that can cause pregnant women to experience iron deficiency anemia, one of which is economic level. Economic level is measured from the poverty level based on daily calorie intake. Poverty is a condition caused by cultural factors in a partickeular area that occur in a particular person or group of people, thereby causing them to remain attached to poverty. This study aims to determine the relationship between economic level and the incidence of iron deficiency anemia in pregnant women in Bandung City. The method used in this research was a retrospective cohort approach. The data used is secondary data from the Bandung City Health Service and the Bandung City Central Statistics Agency. Statistical tests use Spearman rank. The research results show a value of p=0.704 (p>0.05). The conclusion is that there is no relationship between economic level and the incidence of iron deficiency anemia in pregnant women in Bandung City in the 2015-2020 period. This is because economic level is a factor that indirectly influences the incidence of anemia. Abstrak. Anemia merupakan kondisi sel darah merah yang tidak memenuhi kebutuhan fisiologis tubuh, ini terjadi karena eritrosit didalam tubuh tidak seimbang. Kondisi anemia pun sering terjadi pada wanita hamil, insidensi yang sering terjadi adalah anemia defisiensi zat besi dan keadaan ini memiliki konsekuensi serius untuk ibu dan fetus. Terdapat beberapa faktor yang dapat menyebabkan wanita hamil mengalami anemia defisiensi zat besi, salah satunya tingkat ekonomi. Tingkat ekonomi dinilai dari tingkat kemiskinan berdasarkan asupan kalori per hari. Kemiskinan merupakan keadaan yang disebabkan oleh faktor budaya suatu daerah tertentu yang terjadi pada seseorang atau sekelompok masyarakat tertentu sehingga membuatnya tetap melekat dengan kemiskinan. Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat ekonomi dengan kejadian anemia defisiensi zat besi pada ibu hamil di Kota Bandung. Metode yang digunakan pada penelitian ini adalah dengan menggunakan pendekatan kohort retrospektif. Data yang digunakan adalah data sekunder dari Dinas Kesehatan Kota Bandung dan Badan Pusat Statistika Kota Bandung. Uji statistik menggunakan rank spearman. Hasil penelitian menunjukkan nilai p=0,704 (p>0,05). Kesimpulannya tidak ada hubungan antara tingkat ekonomi dengan kejadian anemia defisiensi zat besi pada ibu hamil di Kota Bandung pada periode tahun 2015-2020. Hasil ini disebabkan karena tingkat ekonomi merupakan faktor yang mempengaruhi secara tidak langsung terhadap kejadian anemia.
Perbandingan Micronucleus dan Karyorrhexis pada Mukosa Lidah Perokok Yolanda Yenolinsky; Yuktiana Kharisma; Ismet Muchtar Nur
Jurnal Riset Kedokteran Volume 4, No.2, Desember 2024, Jurnal Riset Kedokteran (JRK)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrk.v4i2.5024

Abstract

Abstract. Although awareness of the negative health impacts of smoking is increasing, the prevalence of active smokers in Bandung City, especially in the neighborhood of the Islamic University of Bandung campus, remains high. The study was conducted as an observational study with a cross-sectional design, involving 20 smokers at Islamic University of Bandung. It is done by taking a peel of the mucous membrane and tongue and colored with coloring boardicolaou. Hail's research showed on the examination of the mucous membrane of the tongue revealed significant differences, especially in the number of micronucleus, as indicators of the genotoxic impact of tobacco compounds. Smokers have higher rates of cellular changes, such as micronucleus and cariorexis. The findings underscore the need for more effective interventions to reduce the prevalence of smoking in different groups of society, taking into account factors such as education and the type of work. The results provide a basis for the prevention of smoking-related diseases in the campus and the community in general. Abstrak. Meskipun kesadaran akan dampak negatif rokok terhadap kesehatan meningkat, prevalensi perokok aktif di Kota Bandung, terutama di lingkungan kampus Universitas Islam Bandung, tetap tinggi. Penelitian ini dilakukan sebagai studi observasional dengan rancangan cross-sectional, melibatkan 20 perokok di Universitas Islam Bandung. Dilakukan dengan mengambil apusan mukosa bukal dan lidah dan diwarnai dengan pewarnaan papanicolaou. Hail penelitian menunjukan pada pemeriksaan mukosa lidah mengungkapkan perbedaan signifikan, terutama pada jumlah micronucleus, sebagai indikator dampak genotoksik senyawa tembakau. Perokok memiliki tingkat perubahan sel yang lebih tinggi, seperti micronucleus dan karyorrhexis. Temuan ini menggarisbawahi perlunya intervensi lebih efektif untuk mengurangi prevalensi merokok di berbagai kelompok masyarakat, dengan mempertimbangkan faktor-faktor seperti pendidikan dan jenis pekerjaan. Hasil ini memberikan dasar untuk upaya pencegahan penyakit terkait merokok di lingkungan kampus dan masyarakat umumnya.
Reproductive health education and early sexual behavior prevention assistance for Madrasah Aliyah students in Bandung Ermina Widiyastuti; Meta Maulida Damayanti; Ismet Muchtar Nur; Tita Barriah Siddiq; Indri Budiarti; Ayu Prasetia
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol. 9 No. 2 (2024): May 2024
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v9i2.12361

Abstract

Health reproduction knowledge is a crucial factor in preventing acts of early sexual behavior. Early sexual behavior is reflected in many ways, from attraction to different sexes to building a relationship and making physical contact. Adequate knowledge of sexuality in teenagers especially in health reproduction would prevent teenagers from acting in early sexual behavior. This activity aims to increase knowledge about the health of reproductive organs and the prevention of early sexual intercourse among Madrasah Aliyah students. The method used is education regarding the health of reproductive organs, pre-marital sexual psychology, and social jurisprudence approaches. All material is presented interestingly and interactively. This activity found that 63 percent of the participants had previous knowledge of this topic. More than 50 percent of respondents were students, and students had quite good knowledge about reproductive health. Madrasah Aliyah students already have sufficient knowledge about reproductive health, but it has not yet been seen whether it is enough to prevent students from premature sexual behavior. However, we do not have any data regarding the act of early sexual behavior among respondents or how knowledge in health reproduction would relate to the act of early sexual behavior.
Nuclear Changes Features in Buccal Mucosa Smear of Adult Male Smokers Using Pappaniculou Staining Kharisma, Yuktiana; Indriyanti, Raden Anita; Yuniarti, Lelly; Noormartany, Noormartany; Nur, Ismet Muchtar; Yenolinsky, Yolanda
Althea Medical Journal Vol 12, No 1 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n1.3486

Abstract

Background: Tobacco smoke contains a combination of chemicals that could be harmful to the buccal mucosa as the first part of the body that has been exposed. Damage to the buccal epithelial cells has the potential to become a malignant lesion. This study aimed to describe changes in the nuclear epithelial of the buccal mucosa using Pappaniculou staining as an indicator of mucosal damage in smokers.Methods: This was a descriptive analytical study, involving adult male participants from Bale Endah District, Bandung Regency, Indonesia aged >35 years, who had smoked for ≥10 years. Buccal mucosa smear was taken, and the features of nuclear epithelial changes were observed per 500 cells, each at 400x magnification with Pappaniculou stain to evaluate the features of micronucleus, broken egg, karyorrhexis, karyolysis. Those who did not smoke were recruited as a control group.Results: Smokers were mostly light active smokers or kretek cigarettes, with a smoking duration of ≥15 years. The frequency of micronucleus (p<0.001), broken eggs (p<0.001), karyorrhexis (p=0.001), karyolysis (p=0.003) in the buccal mucosal epithelial was significantly different between the smoker and non-smoker groups.Conclusions: All epithelial nuclear changes have shown significant differences between smoker and non-smoker groups. Nuclear epithelial features in smoker may be associated with future malignancies, therefore, smoking cessation programs are necessary to substantially reduce tobacco use, thus fostering a healthy lifestyle for everyone.
Co-Authors Abdul Hadi Hassan Abdul Hadi Hassan Agung Firmansyah Sumantri Ahmad Heru Sopyan Andriane, Yuke Annisa Rahmah Furqaani Asty Sabrina Utami Aurora Rahma Koesdinar Ayu Prasetia Ayu Prasetia Dadi S. Argadiredja Deis Hikmawati Ennok Nisa Islamiati Ermina Widiyastuti Fatimah Lidya Andriani Fatimah Lidya Andriani, Fatimah Lidya Ferry Achmad Firdaus Mansoer Hasrayati Agustina Hendro Sudjono Yuwono Herri S. Sastramihardja Hidayat Widjajanegara Indri Budiarti Indri Budiarti Julia Hartati Lelly Yuniarti Lina Munita Sari Sari Maya Tejasari Meike Rachmawati Meta Maulida Damayanti Mia Kusmiati Muhammad Gibran Al Madani Muthiana Rizky Muthiana Rizky, Muthiana Naufal Fadhillah Alam Neneng Sri Meilani Neng Aneu Nurul Hidayah Noormartany Nurul Izzati Fauzia Pradipto Atyanto Wibowo Raden Anita Indriyanti Radina, Faqih Sally Mahdiani Santun Bhekti Rahimah Sari, Ajeng Kartika Siddiq, Tita Barriah Siska Nia Irasanti Siti Annisa Devi Trusda, Siti Annisa Devi Sri Suryanti Taufik Muhammad Fakih Tita Barriah Siddiq Wida Purbaningsih Yani Triyani Yenolinsky, Yolanda Yolanda Yenolinsky Yuktiana Kharisma Yuktiana Kharisma Yuyun Saputri Zahra Salsabila Firdaus Zulmansyah Zulmansyah