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Prognostic Nutritional Index (PNI) at Admission Predicts In-Hospital Mortality of COVID-19-Infected Patients Haryati, Haryati; Isa, Mohamad; Rudiansyah, Mohammad; Juhairina, Juhairina; Nor, Muhamad; Arganita, Fidya Rahmadhany
Majalah Kedokteran Bandung Vol 57, No 2 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.3930

Abstract

Corona Virus Disease-2019 (COVID-19) was declared a pandemic in March 2020 and caused considerable deaths in all parts of the world. Mortality is influenced by the immune system status and increased vulnerability to infection, both related to nutritional status. The Prognostic Nutritional Index (PNI), calculated using lymphocyte count and albumin levels, may have the ability to more accurately characterize the nutritional and inflammatory conditions of COVID-19 patients. This retrospective study analyzed 967 COVID-19 patients at Ulin Hospital Banjarmasin, Indonesia, by examining demographic data, laboratory results, and PNI in relation to survival outcomes. The study revealed that factors such as age, sex, comorbidities (including hypertension, diabetes mellitus/DM, obesity, etc.), number of comorbidities, and disease severity correlated with mortality. Leucocyte count, lymphocyte count, albumin levels, and PNI all showed significant correlations with survival (p<0.001), suggesting that these factors may serve as useful prognostic indicators for COVID-19 patient’s survival. The PNI was associated with an increased risk of mortality, with a univariate odds ratio (OR) of 0.923. Receiver operating characteristic (ROC) analysis demonstrated that a PNI cut-off value of p<41.9 had a sensitivity of 44.9% and a specificity of 82.4%, with an area under the curve (AUC) of 0.666 (p<0.001). Hence, PNI at admission, which reflects patients' immune system and nutritional status upon hospital admission, can be used as a simple, cost-effective, and reliable predictor of mortality in COVID-19 patients.
Comparison of stingless bee honey and silver sulfadiazine on diabetic wound healing in rat models Fajari, Nanang Miftah; Pranoto, Agung; Perdanakusuma, David Sontani; Prenggono, Muhammad Darwin; Rudiansyah, Mohammad; Nur'amin, Hendra Wana; Syarifa, Yulia; Hasrianti, Nuvita; Saputri, Imelda Nita; Afrianto, Muhammad Irawan; Husna, Annisa Halida
Medical Journal of Indonesia Vol. 34 No. 3 (2025): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257974

Abstract

BACKGROUND Diabetic foot ulcers (DFUs) are a major health concern in Indonesia. Adjuvant therapies may improve healing by avoiding secondary infections, promoting angiogenesis, and supporting oxygen circulation. This aimed to evaluate the effect of stingless bee honey (SBH) from Heterotrigona itama on diabetic wound size in rats (Rattus norvegicus), compared to silver sulfadiazine (SSD). METHODS An experimental study was conducted on 13 diabetic wounds in streptozotocin-induced diabetic rats treated with three types of therapies: SSD (n = 5), pure SBH (n = 5), and SBH with 20% water content (n = 3). The study initially involved 21 rats, but eight died during the diabetes modeling and wound observation phases, presumably due to hyperglycemia. Baseline characteristics did not differ significantly across the groups. RESULTS SBH with 20% water content and pure SBH reduced wound size by 95.1% and 92.1%, outperforming SSD (77.4%), with all therapies showing statistically significant improvement (p<0.05). However, the differences between groups were not statistically significant (p = 0.162). CONCLUSIONS Topically applied SBH is a potential natural therapeutic agent for diabetic wounds, in addition to standard treatment such as SSD.
Sosialisasi manfaat daun Mundar (Garcinia forbesii King) meningkatkan daya tahan tubuh dan melindungi kesehatan ginjal pada kelompok tani wanita di Desa Biih, Kecamatan Karang Intan, Kabupaten Banjar Rosida, Azma; Rudiansyah, Mohammad; Fujiati, Fujiati; Kania, Nia; Nirmalasari, Nila; Devi, Wivina Riza; Hutasoit, Rain Sastiani; Wijaya, Cecilia Octa; Putri, Felicia Cindy Tjoa
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 6 (2025): November (In Progress)
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i6.34650

Abstract

AbstrakPemanfaatan tanaman obat tradisional merupakan praktik budaya yang penting untuk kesehatan mandiri masyarakat. Mundar (Garcinia forbesii King) sebagai tanaman asli Kalimantan, memiliki potensi farmakologis, namun bagian daunnya selama ini kurang dimanfaatkan. Kandungan fitokimia seperti alkaloid, flavonoid, dan fenol pada daun Mundar telah diidentifikasi memiliki manfaat kesehatan. Kegiatan pengabdian masyarakat ini bertujuan untuk menyebarluaskan pengetahuan ilmiah mengenai manfaat daun Mundar sebagai imunomodulator dan nefroprotektor kepada Kelompok Tani Wanita di Desa Biih, Kabupaten Banjar. Sosialisasi diberikan kepada 39 peserta dari kelompok tersebut menggunakan media informasi berupa poster. Peserta diberikan kuesioner untuk mengukur efektivitas kegiatan, dilakukan survei tingkat pengetahuan sebelum (pre-test) dan sesudah (post-test) sosialisasi. Hasilnya menunjukkan peningkatan pengetahuan yang signifikan dari distribusi pengetahuan awal yang “sedang“(38,5%) ke peningkatan pengetahuan yang “tinggi” (94,9% peserta). Kegiatan ini secara efektif berhasil meningkatkan literasi kesehatan berbasis kearifan lokal Kata kunci: Garcinia forbesii King; Mundar; imunomodulator; nefroprotektor; pengabdian AbstractTraditional medicinal plants is an important cultural practice for community self-care in the region. Mundar (Garcinia forbesii King), a plant native to Kalimantan, has pharmacological potential, although its leaves have been underutilized. Phytochemical compounds in Mundar leaves, such as alkaloids, flavonoids, and phenols, have been identified to have health benefits. This community service activity aimed to disseminate scientific knowledge about the benefits of Mundar leaves as an immunomodulator and nephroprotector to the Women Farmers Group in Biih Village, Banjar Regency. Outreach was delivered to 39 participants using posters. Participants were given questionnaires to measure the effectiveness of the activity, with a knowledge survey conducted before (pre-test) and after (post-test) the outreach program. The results showed a significant increase in knowledge, from an initial “moderate” knowledge distribution (38.5%) to a “high” level of knowledge (94.9% of the participants). This activity effectively improved health literacy based on local wisdom. Keywords: Garcinia forbesii King; Mundar; imunomodulator; nefroprotector; devotion