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All Journal BIOWALLACEA PROSIDING SEMINAR KIMIA Jurnal Sains dan Teknologi Pangan JURNAL AGRILAND JOURNAL OF ELECTRICAL AND SYSTEM CONTROL ENGINEERING Forum Ekonomi : Jurnal Ekonomi, Manajemen dan Akuntansi JURNAL PENDIDIKAN TAMBUSAI IDENTIFIKASI: Jurnal Ilmiah Keselamatan, Kesehatan Kerja dan Lindungan Lingkungan Journal of Pharmaceutical and Health Research Jurnal Litigasi Amsir JoEELE TITIK DUA: Jurnal Pembelajaran Bahasa dan Sastra Indonesia Andragogia: Journal of Educational Sciences and Islamic Studies RADIAL: Jurnal Peradaban Sains, Rekayasa dan Teknologi Samota Journal of Biological Sciences Jurnal Pendidikan Islam Al Ikhlas
fatur Rahman, fatur
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Journal : PROSIDING SEMINAR KIMIA

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BEBERAPA JENIS METABOLIT SEKUNDER YANG BERPOTENSI SEBAGAI ANTI KANKER : A MINI REVIEW Rizkirullah, Muhammad Adhitya; Kartika, Rudi; Aswat, Raihan; Mahrus, Muhammad Haissul; Rahman, Fatur; Kurniawan, Andi; Azka, Andi Aulia Urrahman; Sanian, Sanian
PROSIDING SEMINAR KIMIA Vol 3 No 2 (2025): Prosiding SNKT 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Cancer is one of the leading causes of death worldwide, including in Indonesia. This review explores the potential of various plants as sources of anticancer compounds through secondary metabolite analysis. Plants such as Rosa damascena, Wild Onion (Scorodocarpus borneensis Becc), and Acalypha Indica have been studied for anticancer activity using in vitro methods. The results showed that extracts from Rosa damascena had varying IC50 values ​​against various types of cancer cells, including 16.28 μg/mL in liver cancer cells (HepG-2) and 18.09 μg/mL in breast cancer cells (MCF-7). In addition, Wild Onion showed very strong anticancer activity with an IC50 value of 1.1061 μg/mL in L1210 leukemia cells. Secondary metabolites such as flavonoids, alkaloids, and tannins were identified as key components contributing to the anticancer effects. These findings highlight the importance of further research to develop more effective and safe plant-based cancer therapies. Keyword: Anticancer, Cancer, Secondary Metabolites, Plants
Co-Authors A, Gusti Noorlitaria Abshar, Ulil Ahmad Talib AIDA MUSPIAH Ambarawati, Dewi Andi Kurniawan Anny Sartika Daulay Ariyani, Amra Aswat, Raihan Azka, Andi Aulia Urrahman Bulkia Rahim Chairani Siregar Doda, Nurhayati ERNIN HIDAYATI Fahmi Makraja Haris Munandar Nasution Heni Pujiastuti Heridah, Andi Hilman Ahyadi Kasim, Aksah Kurniasih Sukenti Mahmud Arif Mahrus, Muhammad Haissul Maslina, Maslina Mindalisma, Mindalisma Moulana, Mohammad Riefyal Muhamad Ramdan, Muhamad Noviasty, Reny Nur Hanifah Nur Hidayat Nurul Fidia, Salsabila Prabowo, Sulistyo Rizkirullah, Muhammad Adhitya Rudi Kartika, Rudi Sanian, Sanian Siburian, Pamasang S. Siti Anisah Sukiman Sukiman Sukiman Waskito Waskito, Waskito Zainal Abadi Zulfadli Zuraidah Tharo