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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Jurnal Respirasi (JR) Jurnal Layanan Masyarakat (Journal of Public Service) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology International Journal of Social Service and Research Jurnal Ilmiah Kesehatan (JIKA) Jurnal Widya Medika

Rebekah Setiabudi, Rebekah

Department Of Medical Microbiology, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia

Author-ID : 563212

Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Profile of Pulmonary Tuberculosis Patients with Type 2 Diabetes Mellitus in Pulmonary Department Dr. Soetomo General Hospital Surabaya Ayu Rahmanita Putri Soetrisno; Rebekah Juniati Setiabudi; Laksmi Wulandari
Jurnal Respirasi Vol. 6 No. 2 (2020): May 2020
Publisher : Faculty of Medicine Universitas Airlangga

Background: Pulmonary tuberculosis (TB) is the most important infectious disease, caused by Mycobacterium tuberculosis (MTB). Indonesia is the third country with the most prevalent TB cases in the world. Not all people who were exposed to MTB will become active TB, because the immune response is the main determinant. Immunocompromised person, such as patients who have type 2 diabetes mellitus (DM) as a comorbid are more prone to develop active TB infection. This study aimed to analyze the profile of pulmonary TB patients with type 2 DM in Pulmonary Department Dr. Soetomo General Hospital Surabaya.Methods: This was an observational descriptive study with a cross-sectional design. The research data were obtained from the medical records of TB patients with type 2 DM in Pulmonary Department Dr. Soetomo General Hospital Surabaya in January - December 2017.Results: Out of a total of 414 hospitalized patients, 74 patients with pulmonary TB were found with type 2 DM. Only 53 patients fulfilled the inclusion criteria. Gene Xpert results were sensitive (66.7%), previous TB treatment history (54.7%), unregulated type 2 DM (88.4%), RBG with the average of 311.83 mg/dl, PPBS with the average of 263.31 mg/dl, FBG with the average of 238 mg/dl, and HbA1C > 10% (68%).Conclusion: The majority of the patients of pulmonary TB with type 2 DM have average high blood glucose and unregulated DM.

First-Line Anti-Tuberculosis Drug Resistance Pattern Ayurveda Zaynabila Heriqbaldi; Rebekah Juniati Setiabudi; Resti Yudhawati
Jurnal Respirasi Vol. 8 No. 1 (2022): January 2022
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: An important concern regarding TB currently is the case of anti-TB drug resistance; hence research on resistance patterns and risk factors is essential. This study aimed to identify the pattern of first-line anti-TB drug resistance. Methods: This descriptive retrospective study was conducted at MDR-TB polyclinic Dr. Soetomo General Hospital, Surabaya, in 2017-2019. Only complete medical records were included. The variables were first-line anti-TB drug resistance (isoniazid, rifampicin, ethambutol, streptomycin) and patients’ characteristics (age, gender, treatment history, and comorbidities). The drug resistance test was performed using certified culture methods. Results: Among 239 patients, the incidences of resistance to H, R, E, and S were 79.08%, 94.14%, 25.94%, and 20.08%, respectively. The most common patterns were HR (42.26%), R (18.83%), and HRE (12.55%). The largest age group was 45-54 years old (38%). The dominant gender was male (56.49%). The most treatment history category was relapsed patients (48%) and there were more patients with comorbidity (57%). Conclusion: The highest incidence rate of resistance was rifampicin and the most common resistance pattern was HR. Most of the patients were of working age, male, relapse patients, and had comorbidities. An appropriate TB therapy treatment plays an important role in preventing resistance.

Co-Authors Achmad Ardianto Adhima, Fauziah Afif Hidayati Agung Dwi Wahyu Widodo Alimsardjono, Lindawati Anindita Rehana Ayu Rahmanita Putri Soetrisno Ayurveda Zaynabila Heriqbaldi Azzahra, Safira Deby Kusumaningrum Dewi Setyowati Diah Mira Indramaya Didik Didik Handijatmo, Didik Dwiyanti Puspitasari, Dwiyanti Eko Budi Koendhori, Eko Budi Evy Ervianti Farah Meriana Fajrin Hammam Izza Rofiqi Hasan, Helmia Indiastuti, Danti Nur Juniastuti Juniastuti Khairunnida Rahma Laksmi Wulandari M. Yulianto Listiawan Mahrumi Dewi Tri Utami Manik R Wahyunitisari ManikRetno Wahyunitisari Mariska Nuriana Marsha Zahrani Maya Wardiana Ni Made Mertaniasih Nunuk Mardiana, Nunuk Pepy Dwi Endraswari, Pepy Dwi Putri S Wulandari Rahmadewi Rahmadewi Resti Yudhawati Retno Asih Setyoningrum Risky Vitria Prasetyo Rochmanti, Maftuchah Rochmanti Rossyanti, Lynda Sawitri Sawitri Silvia Sutandhio Sri Ratna Dwiningshih Suhintam Pusarawati Sulistiawati Sulistiawati Titiek Sulistyowati Utami Meilanie Putri Wahyunitisari, Manik Retno Warella, Juen Carla

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