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Faktor Koreksi Nilai Laju Endap Darah (LED) Pada Penderita Tuberkulosis Menggunakan Metode Westergren dan Wintrobe Dewi, Rizki Amalia; Zaetun, Siti; Jiwantoro, Yudha Anggit
Jurnal Analis Medika Biosains (JAMBS) Vol 8, No 1 (2021): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v8i1.215

Abstract

Pemeriksaan LED bermanfaat untuk memantau perjalanan penyakit dan memantau keberhasilan terapi penyakit kronik misalnya arthritis rheumatoid dan tuberculosis. Metode pemeriksaan LED diantaranya metode westergren dan wintrobe, kedua metode ini merupakan cara manual. Tujuan penelitian pada penelitian ini untuk mengetahui faktor koreksi nilai laju endap darah pada penderita tuberkulosis menggunakan metode westergren dan wintrobe. Metode penelitian yang digunakan pada penelitian ini bersifat pre-eksperimen dengan 2 kelompok perlakuan LED yaitu diuji dengan metode westergren dan wintrobe. Hasil penelitian  didapatkan jumlah hasil pemeriksaan LED metode westergren 622 mm/jam dengan rerata 38,875 mm/jam dan jumlah hasil pemeriksaan LED metode wintrobe 520 mm/jam dengan rerata 32,5 mm/jam. Rentang nilai metode westergren 12-115 mm/jam, rentang nilai metode wintrobe 18-47 mm/jam kemudian hasil pemeriksaan LED dari metode westergren dan wintrobe dikalikan dengan faktor koreksi kemudian hasil perkalian akan dimasukkan dalam rentang nilai masing-masing metode, metode yang hasil perhitungannya lebih banyak berada dalam rentang nilai adalah metode yang lebih baik untuk melakukan pemeriksaan LED. Uji normalitas dan homogenitas tidak berdistribusi normal dan tidak homogen, maka dilanjutkan dengan uji statistik Mann Whitney. Dari tabel hasil analisis Mann Whitney menunjukkan nilai p 0,895 > 0,05. Karena nilai p lebih besar dari α 0,05 maka dapat disimpulkan bahwa tidak terdapat perbedaan yang bermakna antara dua kelompok dengan begitu Ha ditolak. Kesimpulan dari penelitian ini metode westergren adalah metode yang paling baik digunakan untuk melakukan pemeriksaan LED dari pada metode wintrobe karena hasil pemeriksaan metode westergren yang telah dikalikan dengan faktor koreksi lebih banyak berada dalam rentang nilai yaitu 15 hasil perkalian (93,75%).
Differences in Erythrocyte Indices in the First and Third Months of Hemodialysis in Chronic Kidney Failure Patients at Praya Regional Hospital Zahira, Jauhara Rana; Agrijanti, Agrijanti; Getas, I Wayan; Zaetun, Siti
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 2 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i2.464

Abstract

Hemodialysis therapy plays a role in replacing the kidneys' performance in filtering toxins and forming the hormone erythropoietin which forms and matures red blood cells. For this reason, it is necessary to conduct an examination of the erythrocyte index which functions to monitor the severity of anemia caused by chronic kidney failure. This study is a descriptive study with a cross-sectional approach. The sampling technique with purposive sampling is a technique with sample determination according to the researcher with a sample of patients with erythrocyte index examination data in the first and third months of undergoing hemodialysis. Data were analyzed using the Wilcoxon difference test. The total number of complete data of erythrocyte index examination in the first and third months was 22 patients. The average value of the first month erythrocyte index MCV 83.58 fL, MCH 28.31 pg, and MCHC 33.06 g/dL. In the third month the average value of the erythrocyte index MCV 85.35 fL, MCH 28.89 pg, and MCHC 33.90 g/dL. The results of the study stated a significance value of p 0.000 for MCV, MCH value p 0.015, and MCHC value p 0.005. There is a difference in the erythrocyte index in the first and third months of chronic kidney failure patients undergoing hemodialysis
The Effect of Carbohydrate Diet Program on Urine Ketone Positivity with A Long Time on A Diet of One until Three Years Maya, Kadek; Pauzi, Iswari; Zaetun, Siti
THRIVE Health Science Journal Vol. 1 No. 1 (2024): March
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v1i1.165

Abstract

Carbohydrate diet is a diet pattern that reduces carbohydrate consumption. Therefore, the body will use fat as an alternative energy source. The continuous use of fat causes the accumulation of fatty acids so it is often the cause of ketone positivity in the urine. Objective: Find out the effect of a carbohydrate diet program on the positivity of urine ketones. Method this research is an analytic observational study with a cross-sectional approach. The sample used was urine from respondents who had been on a carbohydrate diet for 1 year, 2 years, and 3 years, then urine ketones were examined using the dipstick method. Data analysis was carried out using the Chi-Square test with a confidence value (α = 0.05). Result: The sample in this study amounted to 45 samples, with a total of 23 samples of positive ketones and 22 samples of negative ketones. The results of the Chi-Square test obtained an Asymp.sig value of 0.009 <0.05 (α) which indicates that the carbohydrate diet program has a significant effect on the positivity of urine ketones. The carbohydrate diet program affects urine ketone levels.
Pengaruh Konsumsi Timun dan Bawang Merah terhadap Penurunan Kadar Kolesterol Pasien di Wilayah Kerja Puskesmas Babakan Nandini, Ni Kadek; Zaetun, Siti; Inayati, Nurul; Lale Budi Kusuma Dewi
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.44

Abstract

Hypercholesterolemia is caused by the liver not being able to control LDL in the blood vessels, this condition will cause atherosclerosis and cardiovascular disease. Sterols and flavonoids are content that found in cucumbers which can lower cholesterol by replacing sterols with LDL which will be absorbed in the digestive system. The LDL will be excreted in the form of feces with the help of flavonoids And quercetin is a content found in red onions that can reduce cholesterol levels in the blood by inhibiting the HMG Co-A reductase enzyme. Yankestrad is a program at the Babakan Public Health Center include the use of medicinal plants (TOGA) such as cucumbers and red onions. The purpose of this study is to know the effect of cucumber and red onions consumption on reducing cholesterol levels in patients in the Babakan Health Center work area through the Yankestrad program. Research methods are analytical observational with case control research design and purposive sampling methods. The results of this there is an effect of consuming cucumber and red onions on reducing cholesterol levels.
Perbedaan Jumlah Limfosit dan Monosit serta Morfologi Eritrosit pada Perokok Tembakau dan Elektrik sebagai Faktor Risiko Aterosklerosis pada Remaja Laila Nisa, Isra; Rohmi; Khusuma, Ari; Zaetun, Siti
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.60

Abstract

Background : Smoking from adolescence can increase the risk of atherosclerosis because there is a buildup of fibrolipids and other substances in the blood that can cause plaque. Meanwhile, research results show that e-cigarettes are no less dangerous than tobacco cigarettes. Namely, the number of lymphocytes in e-smokers is 54% and tobacco smokers are 39% (Mega, 2020). The novelty of this research is to look at differences in erythrocyte count and morphology in adolescents at risk of atherosclerosis. Research Objectives : To determine the differences in the number of lymphocytes and monocytes and the morphology of erythrocytes in tobacco and electronic smokers as risk factors for atherosclerosis in adolescents. Research Methods : This research is an analytical observational study with a cross sectional research design and uses the lameshow formula to determine the sample size so that a sample size of 30 samples can be obtained. Data were tested using the Independent T-test and Mann Whitney-U test. The results of the study : The average percentage of lymphocytes and monocytes in tobacco and electronic smoker is 37% & 27% lymphocytes and 7% & 6% monocytes. From 15 samples of tobacco smokers the results were normal and from 15 samples of e-smokers there was 1 lymphocyte result below normal. Also, the abnormal cells found include anulocytes, tear drops, burr cells, ovalocytes and stomatocytes. Conclusion : There are differences in the number of lymphocytes and monocytes as well as erythrocyte morphology in tobacco and electronic smokers as risk factors for atherosclerosis in adolescents with the probability value for lymphocytes being 0.01<0.05 and monocytes 0.04<0.05.
Pemanfaatan Teh Daun Sirsak (Annona muricata L.) Terhadap Kadar Kolesterol Total, Trigliserida Dan Glukosa Darah Pada Pasien Diabetes Mellitus Dengan Hipertensi Rahmayanti, Utari Rizki; Danuyanti, I Gusti Ayu Nyoman; Zaetun, Siti
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 8 No. 2 (2022): Anakes: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v8i2.535

Abstract

AbstrakDiabetes mellitus (DM) merupakan penyakit metabolik dengan karakteristik hiperglikemia dan hiperlipidemia. Yang dimana merupakan faktor resiko terjadinya hipertensi. Makanan yang dapat menurunkan kolesterol, trigliserida dan glukosa darah adalah bahan makanan yang mengandung zat flavonoid dan saponin yang terdapat dalam teh daun sirsak. Artikel ini bertujuan untuk mengetahui manfaat pemberian teh daun sirsak (Annona muricata L.) terhadap kadar kolesterol total, trigliserida dan glukosa darah pada pasien diabetes melitus dengan hipertensi. Desain penelitian ini adalah kuasi eksperimental menggunakan One group pretest-posttest dengan jumlah sampel 10 orang responden. Data yang dikumpulkan berupa data hasil pemeriksaan kadar kolesterol total, trigliserida dan glukosa darah sebelum dan setelah pemberian teh daun sirsak. Rerata hasil pemeriksaan kadar kolesterol total setelah pemberian teh daun sirsak adalah 141.8 mg/dL menurun dibandingkan sebelum pemberian yaitu 182,1 mg/dL (penurunan sebesar 40,3 mg/dL atau 22,13%). Rerata hasil pemeriksaan trigliserida setelah pemberian adalah 172,1 mg/dL menurun dibandingkan sebelum pemberian yaitu 647 mg/dL (penurunan sebesar 474,9 mg/dL atau 73,40%) dan rerata hasil pemeriksaan glukosa setelah pemberian adalah 209,1 mg/dL menurun dibandingkan sebelum yaitu 341,1 mg/dL (Penurunan sebesar 132 mg/dL atau 38,69%). Sehingga pemberian teh daun sirsak selama 30 hari dapat menurunkan kadar kolesterol total, trigliserida dan glukosa darah pada pasien diabetes melitus dengan hipertensi.Kata kunci : Diabetes mellitus, glukosa darah, kolesterol total, teh daun sirsak, trigliserida
EDUKASI DAN PELATIHAN SKRINING PENYAKIT TIDAK MENULAR (PTM) MELALUI PEMBERDAYAAN KADER DAN TENAGA KESEHATAN DI POSYANDU PRIMA Diarti, Maruni Wiwin; Wiadnya, Ida Bagus Rai; Zaetun, Siti; Jiwintarum, Yunan
Jurnal Pengabdian Masyarakat Sasambo Vol. 5 No. 1 (2023): November
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jpms.v5i1.1444

Abstract

Analisis situasi didapatkan data dari Profil Puskesmas Keruak tahun 2021 bahwa pengendalian PTM tahun 2021 tingkat pencapaian/cakupannnya sub variable 63,58% (masih kurang) dari target yang di programkan. Data menunjukkan bahwa pelayanan/skrining kesehatan pada usia produktif, deteksi dini faktor risiko PTM yang ditargetkan 100% capaiannya 40,20%, Penemuan dan pelayanan penderita hipertensi sesuai standart yang ditargetkan 100% capainnya 66,0% serta Penemuan dan pelayanan penderita DM sesuai Standart yang ditargetkan 100% capainnya 63,8 %. Permasalahan yang dihadapi terkait masih kurangnya target capaian tentang pengendalian PTM di wilayah kerja Puskesmas Keruak karena masih kurangnya pelayanan skrining terkait PTM menggunakan pelayanan laboratorium sederhana (Rapid test) terutama ditingkat desa, masih kurangnya pengetahuan kader kesehatan tentang penyebab, pencegahan dan pengendalian PTM, terutama di daerah Desa Mendana Raya Kecamatan Keruak Kabupaten Lombok Timur.  Tujuan kegiatan pengabdian masyarakat ini adalah meningkatkan pengetahuan dan keterampilan kader kesehatan tentang Skrining pencegahan dan pengendalian Penyakit Tidak Menular (Hipertensi, Hipercholesterol, Hiperisemia dan Diabetes mellitus) melalui Posyandu Prima. Solusi permasalahan yang ditawarkan dalam kegiatan pengabdian masyarakat ini adalah dengan Edukasi,penyuluhan dan Pelatihan tentang Skrining pencegahan dan pengendalian Penyakit Tidak Menular (Hipertensi, Hipercholesterol, Hiperurisemia dan Diabetes mellitus) melalui Posyandu Prima. Metode yang digunakan adalah dengan edukasi, pelatihan dan pendampingan menggunakan bookleat, leafleat dan skrining lab sederhana untuk PTM. Hasil dari pengabdian masyarakatTerbentuknya Kelompok Kader Peduli Screening PTM yang telah terampilan dalam penggukuran Tensi dan Pemeriksaan PTM (Kadar Glukosa darah, Asam Urat dan Cholesterol) menggunakan alat POCT.Tercapaianya Peningkatan pengetahuan dan keterampilan kader kesehatan, Petugas kesehatan dan sasaran mitra melalui layanan posyandu prima di desa Mendana Raya tentang skrining kesehatan PTM pada usia produktif dan deteksi dini faktor risiko PTM sampai dengan 100%. Tercapainya peningkatkan pengetahuan dan keterampilan kader kesehatan dan petugas kesehatan tentang pola hidup sehat terkait pencegahan dan pengendalian PTM menjadi sampai dengan 100%. Membantu meningkatkan capaian pelayanan/skrining kesehatan pada usia produktif, deteksi dini faktor risiko PTM yang dari 40,20% menjadi 50,20% tercapai. Membantu meningkatkan capaian Penemuan dan pelayanan penderita hipertensi sesuai standart  dari  66,0% menjadi 77,0% tercapai. Membantu meningkatkan capaian Penemuan dan pelayanan penderita DM sesuai Standart dari 63,8 % menjadi 73,8% tercapai. Tindak lanjut hasil pengabdian masyarakat dalam menjaga keberlanjutan merupakan peran perangkatan desa dan IDUKA dalam posyandu prima terkait skrining kesehatan, pemeriksaan dan pengobatan PTM pada usia produktif yang di buktikan adanya  MOU dan Berita acara penyerahan bantuan Alat tensimeter dan POCT.
Odds Ratio of Increase in Hemoglobin Level Associated with Consumption of Songgak Coffee in Patients with Pulmonary TB Dewi, Lale Budi Kusuma; Hartuti, Sri; Getas, I Wayan; Agrijanti, Agrijanti; Tatontos, Erlin Yustin; Wiadnya, Ida Bagus Rai; Zaetun, Siti; Khusuma, Ari
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pulmonary TB cases in Indonesia are the second highest in the world. The incidence of Anemia in pulmonary TB patients can be as high as 90%. Anemia can lead to poor outcomes in the recovery of pulmonary TB. Songgak coffee is a coffee with a mixture of spices that is commonly consumed by the people of Central Lombok to make the body healthy and increase vitality, including pulmonary TB patients. Songgak coffee is made from 7 types of spices mixed with coffee. The results of previous research show that Songgak coffee has quite good antioxidant content and is an immunostimulant. Antioxidants may increase Hemoglobin levels. This was a case-control study. A total of 26 new pulmonary TB patients were divided into 2 groups. Group A received songgak coffee as an additional anti-TB drug, while group B received anti-TB drug therapy alone. Hemoglobin levels in groups A and B were measured before drug administration and 14 days after treatment. The data collected were nominal data, reported as increasing and non-increasing. A total of 12 out of 13 patients in group A had an increase in Hemoglobin, while only 1 person in group B had an increase in Hemoglobin. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who consume songgak is 12. The odds ratio value for increasing Hemoglobin in pulmonary TB patients taking songgak is 12. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who take Songgak is 12 times higher than in pulmonary TB patients who do not take Songgak.