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Kresnapati, I Nyoman Bagus Aji
Universitas Bumigora
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Isolation of curcumin compounds in Temulawak Rhizome (Xanthorrhiza Roxb) Ramandha, Muhammad Eka Putra; Kresnapati, I Nyoman Bagus Aji
Journal of Natural Sciences and Mathematics Research Vol. 9 No. 2 (2023): December
Publisher : Faculty of Science and Technology, Universitas Islam Negeri Walisongo Semarang

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Abstract

The curcumin compounds in Temulawak Rhizome have been isolated and identified.. This study aims to identify curcumin compounds in temulawak rhizome by modifying methods that pay attention to the efficiency of funds and the use of materials. In general, the method of isolation and identification is carried out. The methods used are (1) Extraction, (2) Thin Layer Chromatography, (3) Column Chromatography and (4) Infrared (IR) Testing. Based on comparing the sample's Retention Factor (RF) value with the standard curcumin compound, the results were identical, and the positive sample contained a curcumin compound. The results of the Infrared spectrum can be assumed that the sample is a flavanols group, which can be seen from the wavelength range of identical functional groups in curcumin compounds.
Pemberdayaan Posyantek Desa Puyung dalam Pengolahan Limbah Menjadi Inovasi Pen dan Colony Counter (SI PINTER): Empowering the Technology Service Center of Puyung Village in Transforming Waste into Innovative Pen and Colony Counter Products through SI PINTER Tool Kresnapati, I Nyoman Bagus Aji; Kurniawan, Salsabila Yunita; Novitarini; Hairul, Hairul; Nikendra, Ni Nengah Naia
DARMADIKSANI Vol 5 No 4 (2025): Edisi Desember
Publisher : Jurusan Pendidikan Bahasa dan Seni, FKIP, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/darmadiksani.v5i4.8439

Abstract

Pengabdian ini bertujuan meningkatkan pemberdayaan mitra dalam inovasi pembuatan alat SI PINTER dari limbah rumah tangga. SI PINTER atau Inovasi Pen And Colony Counter merupakan alat kesehatan yang berperan dalam menghitung jumlah koloni bakteri seperti bakteri pencemar air Escherichia Coli (E. Coli). Pengabdian ini dilaksanakan di Pos Pelayanan Teknologi Tepat Guna (POSYANTEK) Desa Puyung, Kabupaten Lombok Tengah, Nusa Tenggara Barat yang meliputi sosialisasi dan pelatihan pembuatan alat SI PINTER dan promosi alat SI PINTER melalui media sosial. Pemberian lembar kuesioner pre-test dan post-test kepada kader mitra bertujuan menilai tingkat pemahaman pelatihan alat dan promosi alat SI PINTER melalui media sosial. Kuesioner telah teruji secara validitas (r hitung> r tabel 0,344) dan reliabilitas (Cronbhach’s Alpha= 0,961, syarat Cronbhach’s Alpha >0,6). Hasil uji statistik meggunakan SPSS versi 27 Paired-Sample T Test untuk data berdistribusi normal dan Uji Wilcoxon jika data tidak berdistribusi normal. Hasil terdapat peningkatan pemahaman kader sebesar 84% untuk sosialisasi dan pelatihan alat SI PINTER dan 14% untuk promosi alat SI PINTER melalui media sosial. Hasil secara uji statistik menunjukan terdapat perbedaan secara bermakna pemahaman kader mitra setelah penyampaian sosialisasi dan pelatihan alat SI PINTER sebesar p =0,041, (syarat p<0,05) dan secara tidak bermakna untuk promosi alat SI PINTER melalui media sosial sebesar p = 0,066, (syarat p<0,05), sehingga disimpulkan kegiatan pemberdayaan SI PINTER berdampak kepada tingkat pemahaman mitra sasaran.
Sosialisasi Bahaya Penggunaan Antibiotik yang Tidak Tepat sebagai Upaya Pencegahan Resistensi Kresnapati, I Nyoman Bagus Aji; Novitarini, Novitarini; Kurniawan, Salsabila Yunita; Pratiwi, Baiq Yulia Hasni
Alamtana: Jurnal Pengabdian Masyarakat UNW Mataram Vol 6 No 3 (2025): Edisi Desember 2025
Publisher : LPPM UNIVERSITAS NAHDLATUL WATHAN MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51673/jaltn.v6i3.2606

Abstract

Resistensi antibiotik menjadi masalah serius bagi kesehatan secara global akibat penggunaan antibiotik yang tidak tepat. Meskipun aturan pembelian antibiotik dengan resep dokter telah diberlakukan, tingkat kepatuhan masyarakat masih rendah karena dianggap membatasi akses obat. Kegiatan pengabdian ini bertujuan untuk meningkatkan pemahaman siswa-siswi MAN 2 Mataram mengenai bahaya resistensi antibiotik serta pencegahannya. Metode yang digunakan adalah kuisioner berupa pretest-postest untuk mengukur pemahaman sebelum dan sesudah penyampaian materi. Hasil menunjukkan, peningkatan pemahaman sebesar 44,77% dari 37,21% menjadi 81,98% yang menunjukkan tersampaikannya materi yang diberikan dengan baik. Kesimpulan pengabdian ini membuktikan bahwa edukasi mampu menjadi sarana efektif dalam mendorong penggunaan antibiotik secara rasional.
Ethanol Extract of Marigold Flower (Tagetes Erecta L.) Decreases The Total Cholesterol, Low Density Lypoprotein (LDL), Malondialdehyde (MDA), and Apoliprotein B (APOB) on Hyperlipidemia Rat Models Kresnapati, I Nyoman Bagus Aji; Khaerunnisa, Siti; Safitri, Indri
Folia Medica Indonesiana Vol. 57, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

This study aimed to determine the effect of ethanol extract of gemitir flower (Tagetes erecta L.) on total cholesterol levels, Low-Density Lipoprotein C (LDL), Malondialdehyde (MDA), Apolipoprotein B (ApoB). Forty-eight Rattus norvegicus were randomly divided into 6 groups, groups were given standard feed (K-) and 5 groups of hyperlipidemia models (K +, P1, P2, P3, P4) were given High Fat Diet (HFD) for 35 days. On the 36th day, the total cholesterol levels were checked through the tail of Rattus norvegicus, and from day 37 to day 50 were given a normal diet (K-), HFD (K +), simvastatin 10 mg/kgBW (P1), ethanol extract of gemitir flowers (Tagetes erecta L.) 200 (P2), 400 BW (P3), and 800 mg/kgBW (P4). On day 51, the total cholesterol, LDL-C, MDA, and ApoB blood serum levels were checked. The results showed total cholesterol, Low-Density Lipoprotein (LDL), Malondialdehyde (MDA), and Apolipoprotein B (ApoB) given ethanol extract of gemitir flowers 200 and 400 mg/kgBW (P2) had a significant reduction (P < 0.05). Giving ethanol extract of gemitir flower (Tagetes erecta L.) could reduce levels of total cholesterol, LDL, MDA, and Apo B.
Analisis Profil Pemberian Obat Golongan Proton Pump Inhibitor (PPI) pada Penanganan Gastritis Amalia, Aini; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5339

Abstract

Gastritis is an inflammation of the gastric mucosa that is commonly found in healthcare facilities, including Tripat Regional General Hospital. One of the main therapies for gastritis is the use of Proton Pump Inhibitor (PPI) medications, which work by reducing gastric acid secretion. This study aims to understand the profile of PPI administration in gastritis patients at Tripat Regional General Hospital in 2023. This study uses a retrospective descriptive approach, collecting data from the medical records of outpatient and inpatient patients in 2023. The results show that the number of gastritis cases reached 574 patients. The most commonly used PPI medication is omeprazole (38.4%), with the most frequently prescribed dosage being 20 mg (52.3%), and the most common administration frequency is once a day (93.0%). The conclusion of this study indicates that the use of PPI in gastritis patients at Tripat Regional General Hospital is mostly in accordance with guidelines
Analisis Tingkat Kepatuhan Minum Obat terhadap Kejadian Kekambuhan pada Pasien Gastroesophageal Reflux Disease (GERD) Rasyid, M. Gazali Abdul; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5367

Abstract

:  Gastroesophageal Reflux Disease (GERD) is a digestive tract disorder with a rising prevalence both globally and in Indonesia. Recurrence among GERD patients is often linked to medication adherence. This study aims to analyze the relationship between medication adherence and recurrence in GERD patients at RSUD Tanjung in 2024. A qualitative method was used, with data collected from medical records of patients undergoing regular treatment. A total of 84 patients were selected using Slovin's formula from a population of 538 patients. Data were analyzed descriptively and followed by Chi-Square, Homogeneity, and ANOVA tests. The results showed that the recurrence rate among GERD patients was 66%, while the medication adherence rate was only 34%. The Chi-Square test showed no significant relationship between gender and visit frequency. The Homogeneity test indicated that the data variances among groups were homogeneous, and the ANOVA test showed a significant difference based on visit frequency. The study concludes that medication adherence among GERD patients at RSUD Tanjung remains low, contributing to a high recurrence rate. Educational and interventional efforts are needed to improve patient adherence to therapy in order to reduce GERD recurrence rates.
Analisis Kejadian Dispepsia terhadap Faktor Pemicunya Saputri, Syarifa Anita; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5383

Abstract

Analysis of Dyspepsia Incidence Against Trigger Factors in Patients at the Narmada  Health Center. Dyspepsia is a common condition characterized by discomfort or pain in the upper abdomen, and can affect a person's quality of life and have a negative impact on the sufferer's productivity. The purpose of this study was to analyze the incidence of dyspepsia against its triggering factors in Narmada Health Center. This study used a quantitative method with a cross-sectional research design, with a questionnaire instrument that was valid (0.612 - 0.951) and reliable (> 0.90). Results The prevalence of dyspepsia in this study was 164 people based on data from the Narmada Health Center. The frequency of knowledge levels, consuming frogs, exercising on an empty stomach, smoking habits, and the begibung tradition did not show a significant relationship with the incidence of dyspepsia in the community (p-value> 0.05). Meanwhile, the incidence of dyspepsia has a significant relationship with the frequency of consumption of spicy foods, sour foods, fatty foods, raw foods, consuming coffee with a value (p-value <0.05). The conclusion of this study is that the frequency of consumption of spicy foods, sour foods, fatty foods, raw foods, consuming caffeine and drugs are risk factors for the incidence of dyspepsia in the patients at Narmada Health centers
Efektivitas Daun Torbangun (Coleus amboinicus) dalam Menghambat Pertumbuhan Bakteri Bacillus cereus: The Effectiveness of Torbangun Leaves (Coleus amboinicus) in Inhibiting the Growth of Bacillus cereus Bacteria Kresnapati, I Nyoman Bagus Aji; Kurniawan, Salsabila Yunita; Novitarini, Novitarini
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2587

Abstract

This study aims to determine the effectiveness of torbangun leaves (Coleus amboinicus) in inhibiting the growth of Bacillus Cereus bacteria. The urgency of research is due to antibiotic resistance from the use of standard antibiotics, so that the potential of the torbangun leaf plant as an antibiotic candidate is needed. This research method is an experimental study with a Post Test Only Control Group Design research design, namely group (-) in the form of ethyl acetate 96%, group (K +) in the form of Ciprofloxacin antibiotics, treatment group 1 in the form of Ethyl Acetate extract of torbangun leaves (EATL) 20%, treatment 2 EATL 40%, treatment 3 EATL 60% and treatment 4 in the form of EATL 100%. The results showed the widest inhibition zone diameter of 35.0 mm in the (+) standard antibiotic group, followed by EATL 100% 21.7 mm and the lowest Group (-) Ethyl Acetate 96% 8 mm. The results of the One Way ANOVA test showed the effectiveness of torbangun leaves in inhibiting the growth of Bacillus Cereus bacteria with a P value <0.001. Based on the Least Significant Difference (LSD) test, EATL was 100% more effective than other concentrations, but not more effective than standard antibiotics (Group +). The conclusion of this study shows the effectiveness of Torbangun leaves (Coleus amboinicus) in inhibiting the growth of Bacillus Cereus bacteria. Keywords:          Antibacterial; Bacillus_cereus; Coleus_amboinicus; Inhibition_Zone   Abstrak Penelitian ini bertujuan mengetahui efektivitas daun torbangun (Coleus amboinicus) dalam menghambat pertumbuhan bakteri Bacillus Cereus. Urgensi penelitian karena adanya resistensi antibiotik dari penggunaan antibiotik standar sehingga di perlukan potensi tanaman daun torbangun sebagai kandidat antibiotik. Metode penelitian ini merupakan penelitian eksperimen dengan rancangan penelitian Post Test Only Control Group Design yaitu kelompok (-) berupa etil asetat 96%, kelompok (K+) berupa antibiotik Ciprofloxacin, kelompok perlakuan 1 berupa ekstrak etil asetat daun torbangun (EATL) 20%, perlakuan 2 EATL 40%, perlakuan 3 EATL 60% dan perlakuan 4 berupa EATL 100%.  Hasil menunjukkan diameter zona hambat terluas sebesar 35,0 mm pada kelompok (+) antibiotik standar, diikuti EATL 100% 21,7 mm dan terendah Kelompok (-) Etil Asetat 96% 8 mm. Hasil Uji One Way ANOVA menunjukkan efektivitas daun torbangun dalam menghambat pertumbuhan bakteri Bacillus Cereus dengan nilai P <0,001. Berdasarkan uji Least Significant Difference (LSD), EATL 100% lebih efektif dibandingkan konsentrasi lain, tetapi tidak lebih efektif dibandingkan antibiotik standar (Kelompok +). Kesimpulan menunjukkan efektivitas Daun Torbangun (Coleus amboinicus) dalam menghambat pertumbuhan bakteri Bacillus Cereus. Kata Kunci:         Antibakteri; Bacillus_cereus; Coleus_amboinicus; Zona_Hambat
Familiar Edible Flowers in Indonesia I Nyoman Bagus Aji Kresnapati; Muhammad Eka Putra Ramandha; Nurul Indriani
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 01 (2022): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (381.802 KB) | DOI: 10.58549/pcjn.v1i01.7

Abstract

Flowers besides being used as ornamental plants, they can also be consumed. Flowers that can be consumed are called Edible Flowers. Edible flowers in general can be consumed directly, usually in tea or can be served in the form of processed food. Edible flowers contain phytochemical compounds such as anthocyanins, flavonoids, phenolics, carotenoids which are useful as antioxidants. Indonesia is rich in biodiversity with a variety of plant species that can grow, including edible flowers. There is diversity, but only a few edibles that can grow and are familiar to Indonesian people will be reviewed in this article.
Co-Authors Akmi, Alfarizi Muzaifa Amalia, Aini Ana Rahmatyar Anam, M Khairul Anida, Rizki Putri Ayu Dwi Anjani, Desak Sri Ayu Aryani , R . Ayu Ida Baiq Dinda Puspita Ayu Baiq Yulia Hasni Pratiwi Eka Nurul Qomaliyah Hairul Hairul I Gede Angga Adnyana I Ketut Wisnuaji Jayawardhana I Putu Bayu Agus Saputra Indri Safitri Indri Safitri, Indri Jayawardhana, I Ketut Wisnuaji Khaerunnisa, Siti Kurniawan, Nadi Maharani, Reyna Maruni Wiwin Diarti Maruni Wiwin Diarti Muchsin, Lalu Busyairi Mudawil Qulub Muhammad Eka Putra Ramandha Muhammad Haris Nasri Muhsin, Lalu Busyairi Nikendra, Ni Nengah Naia Novitarini Nurul Indriani Ramadhani, Muhammad Wisda Pradja Rasyid, M. Gazali Abdul Rozikin Sabariah Salsabila Yunita Kurniawan Saputri, Syarifa Anita Siti Khaerunnisa Sofya, Sri Winarni Sri Winarni Sofya Yunan Jiwintarum Yunan Jiwintarum