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All Journal Jurnal Bakti Untuk Negeri Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran Inovasi Kesehatan Global Observasi: Jurnal Publikasi Ilmu Psikologi Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Sains Farmasi dan Kesehatan ⁠International Journal of Asian Pacific Community Service Journal of Pharmascience
Yani Ambari
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Religion Agriculture, Biological Sciences & Forestry Humanities Dentistry Economics, Econometrics & Finance Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

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Artikel Review: Pengaruh Variasi Konsentrasi Bahan Pengikat Pada Formulasi Tablet Salut Serta Karakteristik Terhadap Sifat Fisik Sediaan Marcelinda Krisdivayanti; Icasia Carolina Dewi; Laila Sabila Sindriyani; Ana Fatmah Azzahro; Nabyla Qutrun Nada; Alfan Hermawan; Dewi Rahmawati; Yani Ambari; Marthy Meliana Ariyanti Jalmav; Muhammad Fithrul Mubarak
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i4.559

Abstract

Coated tablets are compressed tablets that are coated with a mixture of various substances such as: resin, gum, fillers, sugar, plasticizers, polyols, coloring agents, and flavor enhancers in the active substance. The types of coated tablets that are developing are sugar-coated, thin-coated and enteric-coated tablets. One of the additional materials that plays an important role in making coated tablets is a binder. This review article aims to obtain information and examine what is a good concentration of binder to use in coated tablet formulations. Based on a literature study from several articles collected, it can be concluded that the lactose binder, porang tuber starch, and PVP in several coated tablet dosage formulations, these binders have no effect on the physical properties of the dosage form.
Uji Sediaan Krim Ekstrak Daun Kratom (Mitragyna Speciosa Korth.) yang Berpotensi sebagai Antinosiseptif pada Mencit Jantan Galur DDY Puspita Raras Anindita; Herni Setyawati; Khurin In Wahyuni; Dwi Oktavia Putri; Yani Ambari
Journal of Pharmascience Vol. 10 No. 1 (2023): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i1.12146

Abstract

Penelitian ini bertujuan untuk mengevaluasi potensi antinosiseptif pada sediaan krim ekstrak daun kratom dan menentukan dosis efektifnya. Metode ekstraksi daun kratom yaitu dengan cara remaserasi menggunakan pelarut etanol 70%. Hasil ekstrak kental yang diperoleh dari proses maserasi dimasukkan ke dalam sediaan vanishing cream dengan dosis 0,26 gram; 0,56 gram; dan 0,86 gram. Pengujian antinosiseptif menggunakan metode hotplate test pada mencit jantan galur Deutschland Denken Yoken (DDY). Hasil pengamatan dianalisis menggunakan statistik nonparametrik Kruskal Wallis dan uji persamaan regresi linier. Hasil analisis menunjukkan bahwa ketiga dosis krim ekstrak daun kratom memiliki perbedaan dan pengaruh terhadap jumlah loncatan kaki pada hewan coba jika dibandingkan dengan kelompok kontrol negatif yang berpotensi sebagai antinosiseptif namun kurang bermakna, karena tidak menggunakan kontrol positif. Kata Kunci: Antinosiseptif, Krim,Uji Sediaan, Daun Kratom, Mitragyna speciosa Korth.This study aims to evaluate the antinociceptive potential of kratom leaf ekstract cream and determine its effective dose. The kratom leaf extraction method  used maceration using 70% ethanol solvent. The crude extract obtained from the maceration process is put in to the vanishing cream preparation at a dose of 0.26 grams, 0.56 grams, and 0.86 grams. Antinociceptive testing used the hot plate method on DDY strain male mice. The results of the observations were analyzed using nonparametric statistics “kruskal wallis” and linear regression equation test. The results of analysis showed that the three doses of kratom leaf extract cream had an effect on the number of jumps on the legs of experimental animals when compared to the negative control group which had the potential to be antinociceptive but less significant, because it did not use a positive control.
Co-Authors Abdullah Syafiq Ahmadi Achmad Saichoni Arthaganda Aisyah Adellina Santyas Alfan Hermawan Alfi Dwi Seviah Allyssia Salma Alvito Syawal Z Amelia Saputri Ginting Ana Fatmah Azzahro Anisya’ Khusnul Khotimah Anwari, Farida Arista, Arista Wahyu Ningsih Az Zahra, Maulidya Rachma Bella Fevi Aristia Brelianty Nevy DEWI RAHMAWATI Dian Ayu Oktavia Dila Alvia Rahmasari Dinda Zulia Rahma Dwi Oktavia Putri Dzakiya Zhihrotulwida Dzakiya Zhihrotulwirda Elis Anita Farida Eva Putri Wulandari Faizal Agustino Farid Rahmandani Ferdiana Putri Veronica Fitria Ayu Kusumaningtyas Fitrul Mubarak Heni Amilia Putri Herni Setyawati Herta Meidya Nurhalita Icasia Carolina Dewi Ismatun Maulidiyah Isna Wulan Isnaini Sukmaning M Ivan Charles Laila Sabila Sindriyani M. Fithrul Mubarak Maharani Intan Rusita Maratul Istifadah Marcelinda Krisdivayanti Marselinus Seran Marthy Meliana Ariyanti Jalmav Maulina Apriani Miftahul Maulidiyah Miftakhul Jannah Miya Hartini Nur Wakhid Muhammad Fithrul Mubarak Nabyla Qutrun Nada Nandiyyah Atikah Natalia Abuk Bria Ni’matul Fauziah Nungky Taniasari Oktafia Damayanti Puspita Raras Anindita Rahma Dwi Novitasari Ramadhan Maulana Putra Renny Anggrayni Ria Lestari Herawati Rizki Amalia Putri Safanda Tiara Salsabila Firdausi Hernila Putri Salsabilla Dhiya Atik Nuraini Shabrina Putri Arianti Silfi Maslicha Silvia Nur Diana Putri Siti Khoiriyah Siti Nur Rohmania Tarizza Puspa Anggrelia Tiara Anisa Maharani Vina Aprilia Safari Viola Putri Andini Wahyu Ningsih, Arista Wahyu Ningsih, Arista Wahyu Ningsih Wahyuni, Khurin In Winda Wulandari Yeka Khafidz Illa Rosyidah Zahwa Natasya Novita P