Budi Riyanto Wreksoatmodjo, Budi Riyanto
Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia.

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Efek Neurologis Hipernatremia Carmenita; Budi Riyanto Wreksoatmodjo
Cermin Dunia Kedokteran Vol 50 No 7 (2023): Kardiovaskular
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i7.954

Abstract

Aktivitas otak memerlukan kondisi yang optimal, termasuk lingkungan elektrolit yang ideal. Salah satu elektrolit utama dalam tubuh yang juga penting untuk aktivitas otak adalah natrium. Hipernatremia yang tidak terkoreksi dapat menyebabkan berbagai manifestasi klinis yang bervariasi mulai dari rasa haus, kelemahan, eksitabilitas neuromuskular, hiperrefleks, letargi, confusion, kejang, atau koma. Oleh karena itu, penyebab, gejala, diagnosis, dan penanganan yang tepat perlu untuk mencegah penurunan kualitas hidup pasien.   Brain activities need optimal conditions, including an ideal electrolyte environment. One of the main electrolytes in the body that is also essential for brain activity is sodium. Uncorrected hypernatremia may manifest in symptoms of thirst, weakness, neuromuscular excitability, hyperreflexia, lethargy, confusion, seizure, and coma. Therefore, the causes, symptoms, diagnosis, and appropriate treatment are necessary to prevent a decline in the patient’s quality of life.
Efek Neurologis Hiperkalemia dan Hipokalemia Jason Adiwardhana; Budi Riyanto Wreksoatmodjo
Cermin Dunia Kedokteran Vol 50 No 10 (2023): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i10.1077

Abstract

Electrolyte disorders may interfere with human bodily function. Potassium is the most dominant intracelullar ion; lack (hypokalemia) or excess (hyperkalemia) potassium might give rise to cardiovascular and neuromuscular symptoms. Management consist of potassium serum correction alongside frequent electrocardiography monitoring. Implications of hypokalemia and hyperkalemia should always be taken considered, especially in elderly populations. Central nervous system involvement is currently unknown.
Gangguan Neurologis Pasca-COVID-19 Patricia Michelle Lukito; Budi Riyanto Wreksoatmodjo
Cermin Dunia Kedokteran Vol 51 No 8 (2024): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i8.1532

Abstract

Gangguan neurologis pasca-COVID-19 atau juga dikenal sebagai post-covid neurology syndrome (PCNS) merupakan sebuah kesatuan dari long COVID mencakup berbagai masalah kesehatan yang dapat berlangsung selama beberapa minggu hingga beberapa bulan bahkan mencapai tahunan. Gangguan neurologis ini dapat bervariasi seperti post-COVID fatigue syndrome, gangguan kognitif, anosmia dan ageusia, nyeri kepala, ataupun penyakit seperti stroke dan GBS yang masih memerlukan penelitian lebih lanjut mengenai mekanismenya. Hingga saat ini, belum ada pemeriksaan diagnostik yang pasti, sehingga anamnesis dan pemeriksaan fisik harus tepat. Tata laksana lanjutan diberikan sesuai dengan keluhan.
Tata Laksana Gangguan Kognitif di Layanan Primer: Tinjauan Pustaka Arsanti, Nabila Mayori; Wreksoatmodjo, Budi Riyanto
Cermin Dunia Kedokteran Vol 52 No 9 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i9.1653

Abstract

The global elderly population continues to increase, mainly due to the increase in life expectancy. This condition may pose several problems, i.e., cognitive impairment. Cognitive impairment is a disorder characterized by impairment of cognitive ability and daily functioning, involving disturbances in thinking or memory causing a marked change from the individual’s previous level of functioning with a known or suspected cause. Cognitive impairment is classified into mild cognitive impairment (MCI) and dementia. Cognitive impairment is suspected if there is a decline in work and daily activities. Management in primary care consists of identifying and initial screening, assessments and examinations, and diagnosis. Environmental, psychological, and behavioral interventions; social involvement; nutritional management and sleep interventions; and neuropsychiatric symptom management may be applied. It is important to implement health services that focus on dementia screening and cognitive evaluation in order to prepare healthcare providers. General practitioners can refer patients with early signs or symptoms of cognitive impairment, such as problems with memory or language.
Pemilihan Obat Anti-Epilepsi (OAE) untuk Penyandang Epilepsi Wanita Usia Subur: Tinjauan Pustaka Surianggo, Jenita; Wreksoatmodjo, Budi Riyanto
Cermin Dunia Kedokteran Vol 52 No 1 (2025): Obstetri & Ginekologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i1.1121

Abstract

Epilepsy is the most common chronic brain disorder and can affect people of all ages. Globally, an estimated 60 million people are diagnosed with epilepsy, half of whom are women, and about a third of women with epilepsy are of childbearing age. The main therapy for epilepsy is anti-epileptic drugs to control epileptic seizures. In Indonesia, first-line anti-epileptic drugs are carbamazepine, valproic acid, phenobarbital, and phenytoin, while second-line anti-epileptic drugs are lamotrigine, levetiracetam, clobazam, and topiramate. There are many concerns when women with epilepsy start planning a pregnancy, especially regarding the effect of epilepsy drugs on pregnancy and their effects on the fetus, such as teratogenic effects, neonatal outcomes, and neurodevelopmental impacts. The choice of anti-epileptic drugs (AEDs) in women of childbearing age must be considered carefully.
Gangguan Neurologis Pasca-COVID-19 Lukito, Patricia Michelle; Wreksoatmodjo, Budi Riyanto
Cermin Dunia Kedokteran Vol 51 No 8 (2024): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i8.1532

Abstract

Post-COVID-19 neurological disorders, also known as post-covid neurology syndrome (PCNS), are an integral part of long COVID and include various health problems that can last for several weeks, several months, or even years. These neurological disorders can vary, such as postCOVID fatigue syndrome, ognitive impairment, anosmia and ageusia, headaches, or diseases such as stroke and GBS, which still require further research on the mechanisms. Until now, there has been no definitive diagnostic examination, so the history and physical examination must be precise. Further management is given according to the complaint.