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Muhammad Rizki Saputra, Muhammad Rizki
Universitas Bandar Lampung
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THE EFFECT OF ADMINISTRATION OF COMBINATION OF OVAPRIME HORMONES WITH OXYSTOSIN TO OVULATION AND PRESSING OF SELF-FISHED EGG (Ompok rhadinurus) Saputra, Muhammad Rizki; Nuraini, Nuraini; Sukendi, Sukendi
Jurnal Online Mahasiswa (JOM) Bidang Perikanan dan Ilmu Kelautan Vol 6 (2019): Edisi 1 Januari s/d Juni 2019
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Perikanan dan Ilmu Kelautan

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Abstract

ABSTRACT This research was conducted in May to June 2018 at the Fish Seed Hall Laboratory (BBI) headland of the Fisheries and Marine Service, Rokan District, downstream. The purpose of this study was to determine the efficacy of ovulation and hatching of fish eggs (Ompok Rhadinurus) which were injected with a combination of the hormone ovaprim with oxytocin at different doses. The method used in this study is the experimental method that uses one-factor Completely Randomized Design (CRD) consisting of five treatments with three replications. The treatments applied in this study are: P1: Injection with 25% ovaprim + 75% oxytocin, P2: Injecting with 50% ovaprim + 50% oxytocin, P3: Injecting with 75% ovaprim + 25% oxytocin, P4: Injection with 100% ovaprim, P5: Injecting with 100% oxytocin. The results showed that the best treatment for the effect of ovulation and anchovy egg maturation (Ompok Rhadinurus) was P2: 50% ovaprim + 50% oxytocin which resulted in a latency time of 7 hours 38 minutes, the number of eggs stripping as many as 214 grains / g parent, value ovisomatic index of 16.14%, increase in egg diameter of 0.30 mm, fertilization value of 73.13%, hatching value of 82%, and survival value (SR5 days) of 58.31%. Water quality parameters are: temperature 24-28 ?c, pH: 5-6, DO: 5.2 - 6.3 mg / L. Keywords: Injections, Oxytocin Hormones, Ovaprim Hormones, Stem Fish (Ompok      rhadinurus)
DIAGNOSTIC HISTOPATHOLOGY OF JUVENILE GRANULOSA CELL TUMOR: HALLMARK MORPHOLOGICAL AND CYTOLOGICAL FINDINGS Liana, Nana; Ruhsyahadati, Ruhsyahadati; Triyana, Rahma; Helmizar, Roland; Dhuha, Alief; Malik, Rifkind; Saputra, Muhammad Rizki
Nusantara Hasana Journal Vol. 4 No. 12 (2025): Nusantara Hasana Journal, May 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i12.1417

Abstract

Juvenile granulosa cell tumour (JGCT) is a subtype of granulosa cell tumour that predominantly affects young females, particularly those who are premenarchal, with a mean age at diagnosis of 13 years. Although rare, this tumour can occur across a wide age range, from 10 months to 67 years. Histologically, JGCT resembles the adult-type granulosa cell tumour but presents with distinct features, including aggressive growth and the absence of FOXL2 mutations. Common clinical manifestations include an abdominal mass, abdominal pain, precocious puberty in prepubertal girls due to estrogen secretion, and menorrhagia or amenorrhea in premenopausal women. Macroscopically, the tumour typically exhibits a dominant solid component, frequently accompanied by hemorrhagic and necrotic areas. High mitotic activity and variable degrees of cytological atypia are characteristic findings. The diagnosis is supported by positive immunoreactivity for inhibin, calretinin, and CD99. In early-stage disease, the primary treatment is unilateral oophorectomy with fertility preservation. In contrast, advanced stages often require total hysterectomy and adjuvant chemotherapy. Prognosis is highly dependent on disease stage; patients with stage I disease have a survival rate of up to 97%, whereas advanced-stage disease is associated with a poorer outcome. This review aims to provide a comprehensive overview of the epidemiology, pathogenesis, clinical manifestations, diagnostic approaches, and management strategies of Juvenile Granulosa Cell Tumour (JGCT). It also underscores the importance of early detection and the development of more effective therapeutic options to enhance clinical outcomes.
EDUKASI MENGENAI POLA HIDUP BERSIH DAN SEHAT DI SDN 18 BUKIT KECIL KABUPATEN PESISIR SELATAN Saputra, Muhammad Rizki; Tosi Rahmaddian; Irwadi, Irwadi; Rahma Triyana; Rifkind Malik; Nana Liana; Ruhsyahadati, Ruhsyahadati; Suharni, Suharni; Roland Helmizar; Sri Wahyuni; Alief Dhuha; Betty Fitriyasti1
Nusantara Hasana Journal Vol. 4 No. 12 (2025): Nusantara Hasana Journal, May 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i12.1429

Abstract

Clean and Healthy Living Behavior (PHBS) refers to a conscious effort by individuals to adopt healthy habits in their personal lives, within their families, and in the broader community. PHBS aims to prevent health problems through simple yet effective daily practices. The role of parents, the environment, and teachers is crucial in shaping students' behavior, especially during childhood. However, many elementary school students still lack sufficient knowledge about the importance of clean and healthy living habits. Therefore, educational initiatives are necessary to instill these positive behaviors from an early age. The session was carried out in an educational and interactive manner, incorporating direct practice, games, and quizzes. The PHBS education program took place at SDN 18 Bukit Kecil, Pesisir Selatan Regency, involving 30 student participants. The activity had a clear positive impact on students' knowledge and behavior regarding clean and healthy living practices. The success of the program was supported by strong collaboration between the community service team and the school. It is hoped that similar initiatives will continue to be implemented on a regular basis to cultivate a culture of clean and healthy living from an early age.
THE LEVEL OF KNOWLEDGE, ATTITUDES AND PRACTICES OF MOTHERS ON STUNTING IN NAGARI BUKIK KACIAK LUMPO, PESISIR SELATAN DISTRICT Saputra, Muhammad Rizki; Tosi Rahmaddian; Irwadi, Irwadi
Nusantara Hasana Journal Vol. 5 No. 1 (2025): Nusantara Hasana Journal, June 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i1.1489

Abstract

Stunting is a chronic condition characterized by impaired linear growth in children due to prolonged nutritional deficiencies. It is associated with serious health consequences, including growth failure, developmental delays, and increased risk of non-communicable diseases (NCDs) such as diabetes, cardiovascular disease, and obesity in adulthood. Maternal awareness of nutrition—particularly knowledge, attitudes, and practices (KAP)—is critical in addressing stunting. This cross-sectional observational study was conducted in Nagari Bukik Kaciak Lumpo, Pesisir Selatan Regency, targeting mothers of children who met the inclusion criteria. The data revealed that most respondents were aged 21–60 years, had a high school education, were housewives, and lived in households with two members. The majority of mothers demonstrated good knowledge of stunting, displayed positive attitudes toward its prevention, and engaged in appropriate preventive practices. Conclusion: The study concludes that the majority of mothers in Nagari Bukik Kaciak Lumpo have good levels of knowledge, positive attitudes, and appropriate practices concerning stunting prevention, emphasizing the importance of maternal education in nutritional interventions.
Synthesis of Complex Compounds of Cr(III) Metal Ions and Their Application as Fluorosensors of Pb(II) and Cu(II) in Laboratory Waste Syahputri, Yulian; Sutanto, Sutanto; Kusumawardani, Linda Jati; Saputra, Muhammad Rizki
al Kimiya: Jurnal Ilmu Kimia dan Terapan Vol. 12 No. 1 (2025): June 2025
Publisher : Department of Chemistry, Faculty of Science and Technology, UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ak.v12i1.43967

Abstract

Indonesia's exposure of lead (Pb) and copper (Cu) heavy metal ions to humans and the environment has received increased attention over the past few decades as a result of the increasing application of heavy metals in various industries and transportation. Complex compounds of Cr3+ sensors with fluorescence-based pyrazoline-derived ligands (fluorosensors) have the potential to detect Pb2+ and Cu2+ heavy metal ions. The purpose of this study is to synthesize complex compounds of Cr3+ ions with pyrazoline-derived ligands and its potential as a fluorescence-based sensor of Pb2+ and Cu2+ heavy metal ions. Complex compounds formed are characterized and fluorosensor study by spectroscopic methods. The results showed that the synthesis of complex compounds was successfully carried out and a brown precipitate with a melting point of 253.2°C was obtained. Based on the results of the characterization of complex compounds of Cr3+ metal ions with pyrazolin-derived ligands using a UV-Vis spectrophotometer, two absorption peaks were obtained at 226 and 370 nm, two peaks indicating the presence of transition types π→π* and n→π*. The fluorescence spectrophotometer results showed two emission peaks, the peak absorption maximum of Cr3+ complex compounds was in the region 491 nm with a fluorescence intensity of 320.40 a.u. The determination of the fluorosensor potential of Cr3+ complex compounds with the addition of Pb2+ and Cu2+ metal ions showed significant changes in fluorescence so that fluorosensor types were obtained for Cr3+ metal ion complex compounds with Pb2+ and Cu2+, namely "turn-on" and "turn-off", respectively.
PENYULUHAN TENTANG GIZI SEIMBANG PADA REMAJA DI PONDOK PESANTREN AL-FALAH KOTA PADANG Saputra, Muhammad Rizki; Rifkind Malik; Betty Fitriyasti; Sri Wahyuni; Suharni
Aptekmas Jurnal Pengabdian pada Masyarakat Vol 7 No 3 (2024): APTEKMAS Volume 7 Nomor 2 2024
Publisher : Politeknik Negeri Sriwijaya

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Abstract

Adolescence is a period of human growth and maturity. During adolescence, apart from physical changes, mental and emotional changes also occur which change very quickly. Growth during adolescence demands balanced nutritional needs to achieve maximum growth. Adolescent health and nutrition an important aspects in adolescent life which is the basis of the human life cycle. Lack of understanding among teenagers regarding information on nutrition, health, and other social life problems, so it is necessary to provide education regarding balanced nutrition. The methods used in this service activity are presentations and lectures, discussions, and questions and answers. During this socialization, the students were very enthusiastic about listening to counseling about balanced nutrition for these teenagers. This is proven by the many questions that arise regarding the material presented. This service activity can be considered a very useful activity in efforts to increase teenagers' knowledge about balanced nutrition. Keywords: Balanced nutrition, teenagers, Islamic boarding school
MEKANISME PENSINYALAN VASCULAR ENDOTHELIAL GROWTH FACTOR DALAM PERKEMBANGAN DAN PENYEBARAN KANKER Liana, Nana; Helmizar, Roland; Ruhsyahadati, Ruhsyahadati; Triyana, Rahma; Saputra, Muhammad Rizki
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1598

Abstract

Vascular Endothelial Growth Factor (VEGF) is a key mediator in the process of angiogenesis, playing a crucial role in the development and spread of malignant tumors. VEGF consists of several isoforms, primarily VEGF-A, which exert their effects through receptors VEGFR-1, VEGFR-2, and VEGFR-3, as well as co-receptors neuropilin-1 and -2. Activation of VEGF signaling pathways stimulates endothelial cell proliferation, migration, and survival, increases vascular permeability, and facilitates the formation and invasion of tumor-associated blood vessels. VEGF expression is regulated by various factors, including hypoxia via HIF-1α activation, oncogenes such as KRAS and Src, and the suppression of tumor suppressor genes such as p53 and PTEN. Additionally, several growth factors including EGF, PDGF, and IGF contribute to the regulation of VEGF. VEGF signaling also promotes tumor invasion by activating proteolytic enzymes such as MMP-2, MMP-9, and uPA, which degrade the basement membrane. Due to its central role in angiogenesis and tumor invasion, VEGF is a strategic target in anti-angiogenic therapies for various types of cancer. A comprehensive understanding of the structure, function, and regulation of VEGF is essential for the development of more effective molecular therapies.
Pembuatan Film Animasi 3 Dimensi Tokoh Pahlawan Aceh Teuku Umar Saputra, Muhammad Rizki; Mursyidah, Mursyidah; Husaini, Husaini
Jurnal Teknologi Rekayasa Informasi dan Komputer Vol 4, No 1 (2021): JURNAL TRIK - POLITEKNIK NEGERI LHOKSEUMAWE
Publisher : Politeknik Negeri Lhokseumawe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30811/jtrik.v4i1.2552

Abstract

Abstrak— Film animasi merupakan tontonan yang sangat disukai oleh anak – anak. Tayangan yang disajikan dalam bentuk animasi bermacam-macam, mulai dari hiburan sampai dengan penyajian yang berupa ilmu pengetahuan. Saat ini animasi yang menjadi tontonan terutama anak-anak banyak yang diimpor dari luar. Sementara di Aceh banyak potensi yang dapat dijadikan animasi, salah satu contoh tentang pahlawan Aceh Teuku Umar. Penelitian ini bertujuan menghasilkan sebuah animasi 3D tentang pahlawan Aceh Teuku Umar serta mendapatkan gambaran tentang penilaian responden terhadap animasi yang dimaksud. Data yang tersebut dianalisis dengan cara menghitung persentase. Hasilnya menunjukkan  48% responden menjawab setuju dan  32.33% responden sangat setuju. Dengan demikian dapat disimpulkan animasi ini layak diimplementasikan.Kata kunci— Animasi, Blender, Teuku Umar, 3D movie.
Pembuatan Film Animasi 3 Dimensi Tokoh Pahlawan Aceh Teuku Umar Saputra, Muhammad Rizki; Mursyidah, Mursyidah; Husaini, Husaini
Jurnal Teknologi Rekayasa Informasi dan Komputer Vol 1, No 2 (2018): JURNAL TRIK - POLITEKNIK NEGERI LHOKSEUMAWE
Publisher : Politeknik Negeri Lhokseumawe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30811/jtrik.v1i2.1870

Abstract

Abstrak— Film animasi merupakan tontonan yang sangat disukai oleh anak – anak. Tayangan yang disajikan dalam bentuk animasi bermacam-macam, mulai dari hiburan sampai dengan penyajian yang berupa ilmu pengetahuan. Saat ini animasi yang menjadi tontonan terutama anak-anak banyak yang diimpor dari luar. Sementara di Aceh banyak potensi yang dapat dijadikan animasi, salah satu contoh tentang pahlawan Aceh Teuku Umar. Penelitian ini bertujuan menghasilkan sebuah animasi 3D tentang pahlawan Aceh Teuku Umar serta mendapatkan gambaran tentang penilaian responden terhadap animasi yang dimaksud. Data yang tersebut dianalisis dengan cara menghitung persentase. Hasilnya menunjukkan  48% responden menjawab setuju dan  32.33% responden sangat setuju. Dengan demikian dapat disimpulkan animasi ini layak diimplementasikan.Kata kunci— Animasi, Blender, Teuku Umar, 3D movie.                             
HUBUNGAN FAKTOR RISIKO USIA, PARITAS, DAN LILA PADA IBU HAMIL YANG MELAHIRKAN BAYI BERAT BADAN LAHIR RENDAH (BBLR) DI PUSKESMAS LUBUK BUAYA KOTA PADANG Fitriyasti, Betty; Reza, Tia; Ferilda, Siska; Saputra, Muhammad Rizki; Andani, Wicha Arum
Jurnal Kesehatan Saintika Meditory Vol 6, No 2 (2023): November 2023
Publisher : STIKES Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jsm.v6i2.2170

Abstract

Latar belakang : Banyak faktor yang dapat menyebabkan terjadinya gangguan masa kehamilan yang mempengaruhi tumbuh kembang janin dalam kandungan, berdampak pada berat badan bayi yang dapat menjadi bayi dengan Berat Badan Lahir Rendah (BBLR). Tujuan : penelitian ini untuk mengetahui faktor risiko usia ibu, jumlah paritas dan lila pada ibu hamil yang melahirkan bayi berat badan lahir rendah (BBLR) di Puskesmas Lubuk Buaya Kota Padang tahun 2019-2020. Metode : Jenis penelitian adalah analitik observatorial study. Populasi pada penelitian adalah seluruh ibu yang melahirkan bayi berat badan lahir rendah (BBLR) Tahun 2019- 2020 di Wilayah Kerja Puskesmas Lubuk Buaya Kota Padang sebanyak 40 sampel dengan teknik total sampling. Analisa data univariat disajikan dalam bentuk distribusi frekuensi dan 95% IC serta analisa bivariat menggunakan uji pearson correlation dan pengolahan data menggunakan komputerisasi program SPSS versi 26.0. Hasil : Ibu dengan satu faktor risiko sebanyak 25 orang (62.5%) ibu dengan risiko usia sebanyak 7 orang (17.5%), ibu dengan risiko paritas 2 orang (5.0%), ibu dengan risiko LILA 16 orang (40.0%) dan tidak terdapat hubungan antara ibu dengan satu faktor risko terhadap kejadian melahirkan bayi BBLR p=0.489 yaitu >0.05. ibu dengan dua faktor risiko sebanyak 11 orang (27.5%), ibu dengan risiko usia dan paritas 2 orang (5.0%), ibu dengan risiko usia dan lila 6 orang (15.0%), ibu dengan risiko paritas dan lila 3 orang (7.5%) dan tidak terdapat hubungan antara ibu dengan dua faktor risiko terhadap kejadian melahirkan bayi BBLR p=0.975 yaitu p>0.05. Ibu dengan tiga faktor risiko sebanyak 4 orang (10.0%) dan tidak terdapat hubungan antara ibu dengan tiga faktor risiko terhadap kejadian melahirkan bayi BBLR p=0.241 yaitu p>0.05. Kesimpulan : Berdasarkan hasil penelitian ini dapat disimpulkan tidak terdapat hubungan antara ibu yang memiliki satu, dua, tiga faktor risiko dengan kejadian ibu melahirkan bayi BBLR.Kata Kunci : usia ibu, jumlah paritas, LILA, BBLR.
Co-Authors Abiensy, Salsa Sedilla Adelin, Prima Alief Dhuha Alif Dhuha Andani, Wicha Arum Anissa, mutiara Betty Fitriyasti1 Dhuha, Alief Ellfira, Yeni fatimah Fatimah Febianne, Febianne Fitriyasti, Betty Hasni, Dita Helmizar, Roland Husaini Husaini Irwadi, Irwadi Kendall Malik liana, nana Linda Jati Kusumawardani Lintang Kurniawati Malik, Rifkind Mursyidah Mursyidah Nana Liana Nuraini Nuraini Rahma Triyana Rahmaddian, Tosi Rahmadhian, Tosi Reza, Tia Roland Helmizar Rosmaini Rosmaini, Rosmaini Ruhsyahadati, Ruhsyahadati Siska Ferilda Sri Wahyuni Suharni Suharni Suharni Sukendi Sukendi Sutanto Sutanto Triyana, Rahma Widiastuti, Wisda Yulian Syahputri Yurizali, Bun