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All Journal VISIKES Jurnal Riset Kesehatan JIDAN (Jurnal Ilmiah Bidan) Health Information : Jurnal Penelitian Journal of Applied Health Management and Technology Abdimasku : Jurnal Pengabdian Masyarakat Jurnal Abdidas Infokes : Jurnal Ilmiah Rekam Medis dan Informasi Kesehatan Jurnal Pengabdian UNDIKMA Jurnal Pengabdian Kepada Masyarakat Mulawarman Jurnal Endurance: Kajian Ilmiah Problema Kesehatan Indonesian Journal of Health Information Management Services (IJHIMS) Indonesian Journal of Midwifery (IJM) Medical and Health Journal International Journal of Health Literacy and Science International Journal of Health Science
Wibowo, Syifa Sofia
Universitas Dian Nuswantoro
Religion Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Empowerment of Young Women Through Nutrition Education and Reproductive Health in Stunting Prevention at Mega Islamic Boarding School, Semarang City Pantiawati, Ika; Kusuma, Edi Jaya; Wulan, Widya Ratna; Fani, Tiara; Wibowo, Syifa Sofia
Jurnal Pengabdian UNDIKMA Vol. 7 No. 1 (2026): February
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v7i1.19309

Abstract

This community service program aims to improve adolescent girls’ knowledge of balanced nutrition, anemia prevention, reproductive health, and stunting prevention. The program was conducted at Mega Islamic Boarding High School in Semarang City and involved 47 female students. The intervention was implemented through socialization sessions and interactive educational methods. Program evaluation employed a pre-test and post-test design, with data analyzed using a paired-sample t-test. The results indicate an average increase in knowledge scores of 11.21%, with a statistically significant difference between pre-intervention and post-intervention scores (p < 0.05). Educational activities focusing on nutrition, reproductive health, and stunting prevention for adolescent girls have important implications for strengthening the role of schools in promoting adolescent health. The structured boarding school environment positions schools as strategic settings for fostering sustainable health behaviors. Therefore, it is recommended that health education activities be integrated into extracurricular programs or dormitory guidance and supported by the establishment of adolescent health teams or student health cadres as agents of change through a peer education approach. Furthermore, sustained partnerships with community health centers and universities should be strengthened to support mentoring, evaluation, and program sustainability, ensuring that initiatives to improve adolescent girls’ health literacy contribute meaningfully to the long-term prevention of stunting.
Synthesizing The Evidence: TP53 Mutations as a Prognostic and Predictive Biomarker in Breast Cancer Chuvita, Laila; Wibowo, Syifa Sofia
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19146

Abstract

The journey to personalize breast cancer therapy increasingly navigates the complex landscape of somatic TP53 mutations, the most frequent genetic drivers of this disease. Moving beyond a simple prognostic badge, we now understand these mutations create a spectrum of clinical behaviors, deeply influenced by their specific functional impact and, critically, by their genetic companions. A systematic literature review was conducted across three major electronic databases: ScienceDirect, ProQuest, and Scopus. The search was restricted to peer-reviewed journal articles published in English between 2021 and 2024 to ensure the inclusion of recent evidence. The confluence of TP53 and PIK3CA mutations stands out as a devastating synergy that heralds a tumor phenotype with profound resistance to common chemotherapy regimens, especially taxanes, and the direst survival outcomes. This genetic context also subtly reshapes responses to HER2-targeted drugs, revealing that TP53's influence is both powerful and context-dependent. A more nuanced profiling, one that accounts for these critical genetic interactions, is no longer a future aspiration but a present necessity. These findings collectively advocate for the integration of comprehensive molecular profiling, including nuanced TP53 and PIK3CA assessment, into clinical decision-making.
Hubungan Pengetahuan dan Sikap terhadap Perilaku Menstrual Hygiene pada Remaja Putri: The Relationship between Knowledge and Attitudes toward Menstrual Hygiene Behavior among Adolescent Girls Indri Bakti Salsabila, Dinar; Syifa Sofia Wibowo
Indonesian Journal of Midwifery (IJM) Vol. 9 No. 1 (2026): Maret 2026
Publisher : Universitas Ngudi waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijm.v9i1.4927

Abstract

Menstruation is a physiological process in women representing sexual reproductive maturity. In this cycle, personal hygiene focused on the genitalia (menstrual hygiene) is a crucial aspect. Poor menstrual hygiene can lead to genital tract infections, which may have long-term health impacts such as infertility and decreased quality of life. Lack of understanding regarding menstrual hygiene can also trigger reproductive health issues, including vaginal discharge, reproductive tract infections (RTIs), pelvic inflammatory disease (PID), and the risk of cervical cancer. Menstrual hygiene behavior is influenced by various factors, including individual knowledge and attitudes. Adequate knowledge and a positive attitude are essential foundations for consistent healthy practices. This study aims to determine the relationship between knowledge and attitudes toward menstrual hygiene behavior among female adolescents. This research employed a descriptive-analytic method with a cross-sectional approach. The population consisted of first-year Midwifery Diploma students at Poltekkes Semarang, with a total sample of 118 respondents selected via total sampling. Data were collected using questionnaires distributed via Google Forms and analyzed using the Chi-Square statistical test. The respondents' age range was 17–19 years. Findings showed that 90.7% of respondents had previously received information about menstrual hygiene, with 26.3% obtaining it through social media. Furthermore, 72% of respondents possessed a high level of knowledge, and 57.6% exhibited a positive attitude toward menstrual hygiene. Bivariate analysis yielded a p-value of 0.000 ($p < 0.05$), indicating a significant relationship between knowledge and menstrual hygiene behavior, as well as a significant relationship between attitude and menstrual hygiene behavior among female adolescents. High knowledge of menstrual hygiene is associated with good hygiene behavior, and female adolescents with positive attitudes tend to practice better menstrual hygiene. These findings are expected to serve as a basis for educational institutions and healthcare providers to improve reproductive health, specifically regarding menstrual hygiene practices among adolescents and students.   Abstrak Menstruasi merupakan hal fisiologis yang akan dialami oleh perempuan yang merepresentasikan kematangan sistem reproduksi secara seksual. Dalam siklus ini, pemeliharaan kebersihan diri yang berfokus pada organ genetalia ketika menstruasi (menstrual hygiene) menjadi aspek yang sangat krusial. Perilaku menstrual hygiene yang kurang baik dapat menyebabkan infeksi organ genital. Infeksi pada saluran reproduksi dapat memberikan dampak jangka panjang bagi kesehatan, seperti risiko kemandulan yang pada akhirnya dapat menurunkan kualitas hidup seseorang. Kurangnya pemahaman menstrual hygiene juga dapat memunculkan gangguan kesehatan reproduksi seperti keputihan, infeksi saluran reproduksi, penyakit radang panggul dan kemungkinan terjadi kanker leher rahim. Perilaku menstrual hygiene seseorang dapat dipengaruhi oleh berbagai faktor, di antaranya pengetahuan dan sikap individu. Pengetahuan yang memadai mengenai menstruasi dan kebersihan menstruasi menjadi dasar penting dalam membentuk perilaku yang sehat. Selain pengetahuan, sikap juga berperan penting dalam menentukan perilaku menstrual hygiene. Sikap positif terhadap kebersihan menstruasi akan mendorong individu untuk menerapkan praktik menstrual hygiene yang baik secara konsisten. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan dan sikap terhadap perilaku menstrual hygiene pada remaja putri. Metode penelitian dalam penelitian ini menggunakan   deskriptif   analitik   dengan   pendekatan cross-sectional dengan sampel mahasiswa tingkat satu DIII Kebidanan Semarang Poltekkes Semarang. Pengambilan sampel dengan total sampling sehingga didapatkan sebanyak 118 responden. Pengambilan data menggunakan kuesioner dalam bentuk link google form. Analisis data yang digunakan menggunakan uji statistik chi square. Penelitian ini didapatkan bahwa rentang usia responden 17 tahun – 19 tahun, 90,7% responden sudah pernah mendapatkan informasi mengenai menstrual hygiene dan 26,3% mendapatkan informasi melalui media sosial. Berdasarkan hasil penelitian 72% responden memiliki tingkat pengetahuan yang tinggi mengenai menstrual hygiene dan 57,6% memiliki sikap yang positif tentang menstrual hygiene. Berdasarkan hasil uji bivariat didapatkan nilai p-value 0,000 (<0.05), sehingga dapat disimpulkan bahwa terdapat hubungan antara pengetahuan terhadap perilaku menstrual hygiene dan terdapat hubungan antara sikap terhadap perilaku menstrual hygiene remaja putri. Pengetahuan menstrual hygiene yang tinggi berhubungan dengan perilaku menstrual hygiene yang baik dan remaja putri dengan kategori sikap positif memiliki perilaku menstrual hygiene yang baik. Hasil penelitian ini diharapkan dapat menjadi dasar bagi institusi pendidikan dan tenaga kesehatan dalam meningkatkan kesehatan reproduksi, khususnya terkait praktik menstrual hygiene pada remaja dan mahasiswa.
Co-Authors Adadiyah, Min Alfiena Nisa Belladiena Alfiena Nisa Belladiena Andreas Wilson Setiawan Anggraini, Tyas Apriyanti Apriyanti Arga Satya, Hazel Aries Setiawan Arif Kurniadi Ashari, Ayu Atsala Vindramekka, Rajwa Ayu Ashari Belladiena, Alfiena Nisa Chuvita, Laila Eti Rimawati Fahmi Amiq Fitria Wulandari Fitriyani, Salsabila Hadi, Heru Pramono Hendriani Selina, Hendriani Heni Pujiastuti Ika Pantiawati Indri Bakti Salsabila, Dinar Koes Oktariana Dyah Ramadhani, Rizki Kusuma, Edi Jaya Kusumawati, Nugraheni Laila Chuvita Laurensius Tokan, Geraldinho Nisa Rani Khoirun, Nayla nugraheni kusumawati Octaviani, Dhita Aulia Octaviani, Dhita Aulia Oki Setiono Rahel Amanda Konoralma Respati Wulandari Salsabila, Dinar Indri Bakti Septiani, Cintia Adinda Setijaningasih, Retno Astuti Sri Wahyuni Tiara Fani Wibowo, Syarifah Aqil Wulan, Widya Ratna Yumna Huwaida, Imtiyaz