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Intravitreal Ranibizumab Injection as A Treatment for Diabetic Macular Edema Defayudina Dafilianty Rosataria; Ramzi Amin
Sriwijaya Journal of Ophthalmology Vol. 3 No. 2 (2020): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v3i2.44

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Introduction: In general, diabetic retinopathy is classified into early stage, namely non proliferative diabetic retinopathy (NPDR), and advanced stage, proliferative diabetic retinopathy (PDR). Diabetic macular edema is the most common cause of visual impairment in cases of early stage or NPDR. Purpose: To describe Diabetic Macular Edema (DME) with intravitreal injection of anti-VEGF as a treatment. Case presentation: 43 old female, came with chief complaint of blurred vision on her right eye since six months ago. Blurring is felt slowly. Patient has a history of uncontrolled diabetes since 10 years and a history of hypercholesterolemia since 1 year ago. visual acuity of the right eye is 4/60. On posterior segment examination, neovascularization of the papilla was found. Decreased foveal reflex (+), hard exudates (+) within 500 µm from the central macula. Microaneurism (+), dot hemorrhage (+), blot (+) in 4 quadrants, hard exudates (+) in 2 quadrants in her right eye. The patient was planned for intravitreal injection of anti-VEGF on her right eye. Conclusion: Intravitreal injection of anti-VEGF can improve visual acuity and reduce exudate and hemorrhage in retina from ophthalmoscope and fundus photography examination. In addition, the investigation with OCT was found to improve with reduced macular thickness.
Risk Factors for Diabetic Retinopathy Naufallah Dinda Harumi; Ramzi Amin
Sriwijaya Journal of Ophthalmology Vol. 3 No. 2 (2020): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v3i2.46

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Introduction. Diabetic retinopathy is a progressive microangiopathy characterized by damage and occlusion of small blood vessels. The earliest pathologic changes are thickening of the capillary endothelial basement membrane and a reduction in the number of pericits. Diabetic retinopathy is the main cause of vision loss in type 1 of DM patients and has various risk factors such as chronic hyperglycemia, hypertension, hypercholesterolemia, and elevated HbA1C levels. Methods. This research was conducted using a descriptive observational analytic method with a cross sectional approach at The Eye Polyclinic Dr. Mohammad Hoesin General Hospital Palembang used secondary data on diabetic retinopathy patients. The sample consisted of 64 patients with a total sampling technique, there were 50 patients who met the inclusion criteria. Results. There was a significant relationship between HbA1C levels (p value = 0.050) with a PR value = 1.463 and total cholesterol (p value = 0.038) with a PR value = 1.667 for diabetic retinopathy. Conclusion. HbA1C levels and total cholesterol are significant risk factors for diabetic retinopathy.
PUBLIC EDUCATION ABOUT EYES DURING THE COVID-19 PANDEMIC Ramzi Amin; Petty Purwanita; Prima Maya Sari
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.338 KB)

Abstract

In December 2019, a case of pneumonia of unknown etiology first reported in Wuhan, Hubei Province, China. (1) The etiology was finally identified and showed a new type of coronavirus, which was given the tentative name 2019 novel coronavirus (2019-nCoV). On February 11, 2020, the World Health Organization (WHO) announced the name of the new virus, namely Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), and the name of the disease as Coronavirus Disease (COVID-19).Indonesia reported its first two confirmed cases of COVID-19 inMarch 2, 2020. As of September 8, 2020, the number of confirmed cases of COVID-19 in Indonesia was 200,035, with 8,230 deaths (CFR 6.9%).
Evaluation of the Dengue Hemorrhagic Fever Eradication Program in Palembang Galuh Ismayanti; Chairil Anwar; Rizma Adlia Syakurah; Ahmad Ghiffari; Ramzi Amin
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 13 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i13.637

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Background: Dengue Haemorrhagic Fever (DHF) has the potential to cause Extraordinary Events (KLB), hence the government has made efforts to control DHF, one of which is through the PSN program. Evaluation is necessary to determine how the implementation of the PSN program is following the planned objectives and whether the program can control the breeding of mosquito larvae to reduce the number of dengue cases in Palembang City. Methods: This study utilized a qualitative method with an analytical descriptive approach. The CIPP evaluation model was used to evaluate the context, input, process, and product to determine the success of the PSN program. The information was obtained from twelve informants who were recruited by purposive sampling. Results: The study data was collected in the form of interviews, observations, and a document review to evaluate the dengue fever mosquito nest eradication program (PSN) in Palembang City in 2022. In general, the PSN program has gone well but is still constrained by budget. Furthermore, SOPs related to eradicating mosquito nests do not yet exist and there is a lack of community participation. Conclusion: It is anticipated that Palembang City Health Office can use these study findings as a basis to justify budget allocation for the mosquito nest eradication program and develop SOPs regarding the eradication of mosquito nests to facilitate the program. They could also improve coordination, participation, and community empowerment to implement a larva-free village competition and providing a reward for villages that have been declared larva-free by the Puskesmas to encourage community participation in the eradication of mosquito nests.
Analisis Implementasi Kebijakan Pelayanan Gizi Rumah Sakit Rujukan Covid-19 di Kota Palembang Devi Eryanti; Charil Anwar; Yuanita Windusari; Nur Farida Rahmawati; Ramzi Amin; Maya Ija
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (362.265 KB) | DOI: 10.36418/syntax-literate.v7i6.7311

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Latar Belakang: Gizi menjadi hal penting dalam menjaga sistem kekebalan tubuh. Pasien COVID-19 memerlukan dukungan gizi yang menyeluruh untuk proses kesembuhan. Tujuan: Menganalisis implementasi kebijakan pelayanan gizi Rumah Sakit Rujukan COVID-19 di Kota Palembang. Metode: Penelitian kualitatif melalui wawancara mendalam pada 30 orang informan (5 Kepala Seksi Gizi, 5 Kepala Instalasi Gizi, 5 ahli gizi, 10 tenaga pengolahan, dan 5 pramusaji). Instrumen penelitian yaitu panduan wawancara dan observasi. Analisis data secara deskriptif dan triangulasi. Hasil: Implementasi kebijakan pelayanan gizi: (a) standar dan tujuan kebijakan direalisasikan dan diperkuat dengan Surat Keputusan Direktur, (b) Sumber dana, sumber daya manusia dan fasilitas memadai, (c) Karakteristik organisasi pelaksana sudah menerapkan kebijakan dengan pasti, (d) Komunikasi antar pelaksana dilakukan, tetapi hambatannya tidak patuhnya pelaksana tugas, (e) Sikap pelaksana sangat mendukung, namun terkendala kesenjangan pengetahuan, (f) Keadaan sosial ekonomi dan politik berjalan baik dan didukung semua aktor kebijakan (Kepala Seksi, Kepala Bidang, Direktur, Organisasi Profesi, dan Pemerintah pusat). Kesimpulan: Belum optimalnya implementasi kebijakan karena sikap pelaksana tidak konsisten. Diperlukan peningkatan pengetahuan COVID-19, terutama bagi tenaga gizi, pengolah, dan pramusaji, dan diperlukan peningkatan kerjasama seluruh lembaga terkait dan stakeholders untuk mendukung kebijakan pelayanan gizi, sehingga menjadi prioritas dalam proses penyembuhan pasien COVID-19.
Relationship between Retinal Nerve Fiber Layer with Visual Field Defect in Non Proliferative Diabetic Retinopathy Alfurqon Alfurqon; Ramzi Amin; AK Ansyori
Majalah Oftalmologi Indonesia Vol 41 No 3 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v41i3.43

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Background: In the early stages of diabetic retinopathy, neuronal abnormalities include changes in ganglion cell death. Neuronal apoptosis is suspected as one of the causes responsible for the occurrence of lesions at an early stage of diabetic retinopathy, which results in a decrease in number of ganglion cells and thinning of the layer of ganglion cells, which can be caused by several mechanisms including glutamat excitoxicitate, oxidatice stress, hyperglichemia, and neuroinflamation. Retinal ganglion cell death and axonal degeneration, will cause thinning of the retinal nerve fiber layer (RNFL) which may result in a decrease in neural function, which in turn have an impact on the occurrence of visual field defects. This study is to determine the relationship between the thickness of RNFL with visual field defects in patients with non-proliferative diabetic retinopathy (NPDR). Methods: This study is a comparative analytic cross-sectional design with sample of 66 eyes of 34 people in clinic of retina subdivision of Moh. Hoesin Hospital Palembang from July to November 2013. Patients of NPDR examined fundus photo, Oculo Coherence Tomograph and Humphrey Field analyzer. Results: RNFL thickness average in this study is 104.4±10.9 μm. Visual field defect occur ini moderate and severe NPDR. Conclusion: There is a strong relationship between RNFL thickness with visual field defects in patients NPDR (r =-0.693). Keywords: RNFL thickness, visual field defect, NPDR  
Upaya meningkatkan kesadaran masyarakat dalam menjaga kesehatan mata di masa pandemi Covid-19 Purwanita, Purwanita; Amin, Ramzi; Sari, Prima Maya; Anggraini, Rika; Rosataria, Defayudina Dafilianty; Salim, Muhammad Usman
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 2 No 2 (2021): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V2I2.58

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The SARS-CoV-2 virus is part of the coronavirus family. Currently, transmission of SARS-CoV-2 through droplet that come out when coughing, sneezing or contact is believed to be the main route of transmission of the virus. Eye involvement in cases of COVID-19 has been reported in several journals. Research in Hubei, China, reported that 12 out of 30 confirmed COVID-19 patients were accompanied by conjunctivitis. One of the COVID-19 positive patients with conjunctivitis in Italy detected SARS-CoV-2 RNA in an eye specimen which may be a potential source of infection. Several studies have emphasized that the eyes are a potential entry point for the virus and emphasize the importance of masks and eye protection. Until now, there is no vaccine or specific treatment to deal with COVID-19, so prevention is the best step to take. Lack of public knowledge in recognizing how the SARS-CoV-2 virus is transmitted so that they are less introspective and do not take precautions for virus infection. Educational videos regarding things that must be considered about the eyes during the COVID-19 pandemic can be a means of health promotion to prevent the spread of infection. This community service is expected to attract the attention of the public to get to know COVID-19 and increase public awareness of how much we should work together to reduce the transmission of this virus.
Epiretinal Membrane Management for Young Adult Patient: A Case Report Zamzam, Avizena Muhammad; Ramzi Amin; A.K Ansyori
Sriwijaya Journal of Ophthalmology Vol. 7 No. 1 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i1.113

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Introduction: Epiretinal membrane (ERM) is a condition where a thin fibrotic tissue layer appears on the surface of the macula, which causes a decrease in visual acuity. There are still limited data about the management of ERM due to its low incidence. We reported a case of epiretinal membranes in young adult patients. Case presentation: A 40-year-old male complained of blurry vision on the left eye since 6 months ago. His visual acuity was reduced, and a fundus photograph and macula OCT examination were performed. He was diagnosed with left eye epiretinal membrane and planned for left eye membrane peeling. The retinal break was found intraoperatively as a suspected predisposing factor. Conclusion: Management of severe ERM focuses on reducing metamorphopsia, improving visual acuity, and improving binocularity with pars plana vitrectomy combined with membrane peeling. At a young age, the predisposing factors for secondary development must be further identified.
A 39-Year-Old Woman with Oculodermal Melanocytosis: A Case Report Fensilia Yolanda, Gina Sonia; Ramzi Amin; H. A. K. Ansyori
Sriwijaya Journal of Ophthalmology Vol. 7 No. 1 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i1.114

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Introduction: Nevus of Ota, also known as oculodermal melanocytosis (ODM), is characterized by macular pigmentation which localized to the forehead and periocular area. It usually shows a dermatomal distribution from the first two branches of the trigeminal nerve. We reported a case of oculodermal melanocytosis (ODM). Case presentation: A 39-year-old woman, came with complaints of her left eye rolling inwards for the past 5 years accompanied by a flat black spot on her forehead that spread to her left cheek. She was done macular OCT and orbital ultrasonography of the left eye. She was diagnosed with oculodermal melanocytosis in the left eye, moderate NPDR in both eyes, juvenile cataracts in both eyes, and esotropia in the left eye due to left-eye cranial nerve VI paralysis. Follow-up at 6 months was advised to the patient. Conclusion: Although this is a benign condition, patients are at risk of developing complications such as increased intraocular pressure and melanoma of the skin and/or uvea, ongoing evaluation with imaging methods is highly recommended even if only skin lesions may be repaired using laser for cosmetic reasons.
Management of Wet Age-Related Macular Degeneration: A Case Report Handayani, Retno Tharra; H. A.K Ansyori; Ramzi Amin
Sriwijaya Journal of Ophthalmology Vol. 7 No. 1 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i1.115

Abstract

Introduction: Age-related macular degeneration (AMD) is a progressive neurodegenerative disease of the photoreceptors and retinal pigment epithelium (RPE). It is a leading cause of blindness and visual impairment in the elderly population, despite recent advances in treatment. We reported a case of wet AMD and its management. Case Presentation: A 69 years old woman complained of blurred vision, especially in the left eye, which she had experienced since 3 years ago, progressively worsen since the last 3 months. Fundoscopy and OCT examination was done. Fundoscopy found no foveal reflex with a drusen and perifoveal haemorrhage found on left eye. She was diagnosed with wet age-related macular degeneration type II of left eye. She had done intravitreal anti-VEGF injection with local anaesthesia. Conclusion: AMD management relies heavily on observation, lifestyle changes, frequent follow-up evaluations, early recognition of visual impairment and detection of CNV. Meanwhile, the current modality for wet AMD therapy is intravitreal anti-VEGF injection to preserve patient’s visual acuity and improve quality of life.
Co-Authors A.A. Ketut Agung Cahyawan W A.K Ansyori Ahmad Ghiffari Alfin Radhian Alfurqon Alfurqon Ammar Fardhana Ansyori, A.K. Ansyori, AK Ansyori, AK. Ashita Hulwah A Ayu Aliyah Aziztama, Rezandi Budi Santoso Chairil Anwar Chairil Anwar Charil Anwar Cicilia, Monica Putri Cindy Kesty Defayudina Dafilianty Rosataria Devi Eryanti Devi Eryanti Dezca Nindita Dian Ariani Dian Puspita Sari Dina Fatwa Dio Asgira Rizky Dita Mintardi Dwiana Ocviyanti Dyah Rahayu Utami Elisa Taurisia Elza Iskandar, Elza Evasha, Agung Putra Faika Novadianaz Faiz Muhammad Ikhsan Faneisha Febrina Art Fensilia Yolanda, Gina Sonia Ferry Yusrizal Fidalia Galuh Ismayanti Ginda Chitra H. A. K. Ansyori H. A.K Ansyori Haloho, Agustina Br. Hamzah Hasyim Handayani, Retno Tharra Hartati Hartati Herdana, Nova Indiarsih, Tiara Bunga Indri Seta Septadina Irsan Saleh Kms Yusuf Effendi Krisna Murti Laksono Trisnantoro Linda Tri Wulandari M. Usman Salim Mandy Putriyudi Maria Ulfa Maya Ija Maya Sari, prima Mgs. Irsan Saleh, Mgs. Irsan Mistur Rozian Mufida Muzakkie Muhammad Baqir MUHAMMAD FAHMI Muhammad Irsan Saleh mulyati mulyati Mutiara, Ria Nailul Authoriyah Naufallah Dinda Harumi Nova Herdana Nur Farida Rahmawati Nyayu Fauziah Zen Oliffa Salma Atthahiroh Petty Purwanita Prima Maya Sari Purwanita, Purwanita Putra, Chani Sinaro Putri, Dwi Octaverina Radiyati Umi Partan Rafika Rafika Novianti Rahmah, Meidina Rajendra Ekki Maulana Reny Violeta Rika Anggraini Rika Anggraini Ririn Rahayu Ririn Rahayu MS Rizma Adlia Syakurah Roland Iqbal Rosataria, Defayudina Dafilianty Salim, Muhammad Usman Shaelva Lassa Sabatini Shariff, Muhammad Apriliandy Silvia Rahmi Siti Pradyta Phiskanugrah Sukmono, Nafila Mahida Syarif Husin Theodorus Tiara Mayasari Tribowo, Anang Vicela Patricia Virgyna Widya Wira Putri Yuanita Windusari Yuanita Windusari Zamzam, Avizena Muhammad Zen Hafy