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All Journal Pharmaciana: Jurnal Kefarmasian UNEJ e-Proceeding JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Science and Technology Indonesia Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JFIOnline J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Journal of Tropical Pharmacy and Chemistry
Dewi Melani Hariyadi
Departemen Farmasetika, Fakultas Farmasi, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

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Drug and cosmetic safety training for cadres of family welfare program Tristiana Erawati; Dewi Melani Hariyadi; Noorma Rosita; Widji Soeratri; Tutiek Purwanti; Hadi Poerwono; Marcellino Rudyanto; Helmy Yusuf; Djoko Agus Purwanto; I Nyoman Wijaya
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol. 9 No. 2 (2024): May 2024
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v9i2.11161

Abstract

In order to increase public understanding and awareness regarding the safety use of drugs and cosmetics, the Community Service Team of the Faculty of Pharmacy, Airlangga University has held community service in Jonggrangan Village, Klaten, Central Java. The community service was carried out on July 31, 2023, with approximately 60 family welfare programs or PKK cadres and health cadres participating through training, presentations, and discussions. The activity began with a pre-test, continued with training, a presentation of the material by three experts, and a discussion, then ended with giving a post-test to the participants. The results of the pre and post-test analysis showed that participants' understanding increased. The results of the analysis of the answers to the 15 questions given showed that the increase in participants' understanding ranged from  2.13-46.02 percent. The impact of these activities on society. The increase in participants' understanding of each topic is not the same depending on the initial understanding. However, the problem is that the level of public understanding after receiving training is still below 50 percent namely on topics about the stages of using cosmetic products and about drug classification. So it is necessary to deepen the material using other strategies (appropriate methods and media).
Effect of CaCl2 Crosslinker Concentration On The Characteristics, Release and Stability of Ciprofloxacin HCl-Alginate-Carrageenan Microspheres Amiruddin; Muh. Agus Syamsur Rijal; Dewi Melani Hariyadi
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 3 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i32023.312-323

Abstract

Background: Ciprofloxacin HCl is a broad-spectrum fluoroquinolone antibiotic that has the lowest MIC against Mycobacterium tuberculosis but has limitations in oral use, so inhalation microspheres are made. Objective: This study aimed to investigate the effect of CaCl2 crosslinker concentration on the characteristics, release and stability of ciprofloxacin-alginate-carrageenan microspheres. Methods: Microspheres were prepared by ionotropic gelation using aerosolization with calcium chloride 0.5M (F1), 1.0M (F2), 1.5M (F3), 2.0M (F4) as crosslinker and then dried using freeze dryer. Results: Ciprofloxacin-alginate-carrageenan microspheres formed of yellowish-white powder, smooth morphology and excellent flow properties with the particle size of less than 5µm, drug loading and entrapment efficiency were between    2.05% - 2.42% and 75.34% - 98.09%, yield was between 84.69% - 97.57%, moisture content of less than 10%. Ciprofloxacin-alginate-carrageenan microspheres with 1.5M crosslinker (F3) was the optimal formula. For 12 hours, ciprofloxacin released was 49.89% - 63.78% at pH 7.4, and the kinetics of drug release showed that of Korsmeyer-peppas with a mechanism based on fickian diffusion. The microspheres were discovered to be stable for up to 28 days of storage. Conclusion: The increased concentration of the CaCl2 crosslinker from 0.5M to 2.0M decreased the particle size and drug release but increased the yield, drug loading and entrapment efficiency.
Co-Authors Amiruddin Amiruddin Andang Miatmoko Aqsha, Aulia Charis Ardhani Dwi Lestari1 Bambang Tri Purwanto Dewi Isadiartuti Dini Retnowati Djoko Agus Purwanto Dwi Setiawan Dwi Setyawan Esti Hendradi Farida Ifadotunnikmah Fauzia Azzahra, Fauzia Hadi Poerwono Hanafi Tanojo Handayani, Rosita I Nyoman Wijaya I NYOMAN WIJAYA Idha Kusumawati Imamatin Nufus Melania Irawan, Mukhlis Bayu Irawan, Mukhlis Bayu Juni Ekowati Khoirotul Lailiyah Kurniawan, Muhammad Fariez Lailiyah, Khoirotul Liempepas, Angelika Mahardian Rahmadi Marcellino Rudyanto Melanny Ika Sulistyowaty Mohammad Agus Sjamsur Rijal Mohammad Rizki Fadhil Pratama Muhamad Ilham Royyan Nafi’ Muhammad Agus Syamsur Rijal Muhammad Faris Adrianto Noorma Rosita Paramanandana, Abhimata Praditapuspa, Ersanda Nurma Putri Hamidah Khairunnisa Rahman, Fakhrinnisa Wildani Rahmi Annisa Regia Nada Asshafa Retno Sari Retno Widyowati Rossa Auli Tasha Sairiyah, Siti Nasikatus Siti Rahmah Sugiyartono1 Suzana Tekla Kalalo Tiara Jeni Rosadi Tristiana Erawati Munandar Tutiek Purwanti Tutik Sri Wahyuni Widji Soeratri Wiwied Ekasari Yusuf, Helmy