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Guntara, Yudi
Universitas Sultan Ageng Tirtayasa
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Journal : Journal of Energy, Material, and Instrumentation Technology

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The Effect of Chitosan Addition on Phase Composition and Detection Sensitivity of Fe3O4/Chitosan Magnetic Label Nanoparticles Based on Giant Magnetoresistance Sensor Prayoga, Galih Aji; Oktarisa, Yuvita; Antarnusa, Ganesha; Fitriani, Nur Shabrina; Aryani, Refi Meilia; Suherman, Andri; Guntara, Yudi
Journal of Energy, Material, and Instrumentation Technology Vol 5 No 4 (2024): Journal of Energy, Material, and Instrumentation Technology
Publisher : Departement of Physics, Faculty of Mathematics and Natural Sciences, University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jemit.v5i4.282

Abstract

This study describes how phase composition affects the ability of giant magnetoresistance (GMR) chip-based sensors to detect magnetic labels made of Fe3O4 and Fe3O4/chitosan that were synthesized using the co-precipitation method. X-ray diffraction (XRD) analysis revealed that the synthesized nanoparticles were a mixture of magnetite and maghemite phases. The most intense diffraction peak at 2θ = 35.6° (311) confirmed the presence of the magnetite phase. The addition of chitosan significantly increased the proportion of the maghemite phase from 10% to 25%, with the appearance of an additional peak at 2θ = 33° (221). The modification of Fe3O4 nanoparticles into Fe3O4/chitosan nanocomposites resulted in changes in sensor sensitivity. The GMR sensor successfully detected Fe3O4 and Fe3O4/chitosan magnetic labels within 30 seconds with high sensitivities of 0.746 and 0.761 mV/( g/mL), respectively. The limit of detection (LOD) was also very low at 0.419 and 0.428 g/mL. These findings show that Fe3O4/chitosan nanocomposites integrated GMR chip-based sensors can be a dependable instrument for detecting a variety of biomolecules such as Bovine serum albumin (BSA).
Co-Authors Abdilah, Meilani Nisa Albab, Hikmah Hafsah Latifah Alfian, Iqbal Andri Suherman Annida, Alzahranitia Anugrah, Azyumardi Rais Aroya, Shela Widia Aryani, Refi Meilia Aryati, Deni - Asep Saefullah Asroriah, Siti Astari, Rana Putri Awaliah, Silwi Kulsum Azkia, Muhamad Bunyamin, Muhammad Abd Hadi Damayanti, Nurfuzi Defi, Defi Defitri, Sarah Aulia Desi Ratnasari Dewi, Sharani Fadilah, Aditya Akmal Fathia, Fathia Fauziah, Siti Sepiyanti Firdaus, Rakhman FIRMAN PERMANA Firmanul Catur Wibowo Firna, Firna Ardiyana Fitri, Amelia Febriana Fitriani, Nur Shabrina Ganesa Antarnusa Gunawan, Agun Hafid, Tubagus Hakim, Hafied Rahman Harisudin, Ahmad Havid Noor Pamungkas, Havid Noor Hidayatullah, Subhan Inayatullah, Husnaini Khairunnisa Khairunnisa Komarudin Komarudin Kristiaji, Darmawan Kriswahyudi, Bambang Kusuma, Bintang Lina Herlina Listiyani, Hanum M. Fauzan Abdillah Maharani, Anissa Listiana Marquerette, Lindi Utami Marwanti, Kissi Mila Nuridhati Muhammad Alif Muna, Chynta Nadya Muslih, Abiyyu Oktavian Nurfadilah, Annisa Nurlia, Siti Rosyadah Nurlia, Siti Rosyadah Nurul Aeni Oktorisa, Yuvita Pramugia, Weli Pratama, Arel Rizky Prayoga, Adam Fori Prayoga, Galih Aji Rahmat Firman Septiyanto, Rahmat Firman Rasiana, Rara Riadah, Riadah Ripadli, Ripadli Riswandi, Reza Rosihah, Nur Rostikawati, Diana Ayu Rudi Haryadi, Rudi Safitri, Alda Sari, Diah Permana Sari, Indah Fatika Septiani, Nia Siti Romlah Sucipto, Imam Suhenda, Dede Panji Syam, Muhamad Tabrani, Rizqi A’mal Hibatullah Tanjung, Winnei Ray Beatrix Veronika, Elisabeth Yana Mulyana Yayat Ruhiat Yogi Permana Yuvita Oktarisa, Yuvita