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All Journal Journal of Food and Pharmaceutical Science Pharmascience Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Window of Health : Jurnal Kesehatan Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Hydrogen: Jurnal Kependidikan Kimia Mejuajua Pharmaceutical Reports Journal Microbiology Science Journal of Food and Pharmaceutical Sciences Indonesian Journal of Jamu MPSJ
Selpida Handayani, Selpida
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A Standardisasi Buah Dengen (Dillenia serrata Thumb.) Handayani, Virsa; Putri, Andra Audina; Handayani, Selpida
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.156

Abstract

Dengen (Dillenia serrata Thumb.) merupakan tumbuhan endemik yang tumbuh liar di Sulawesi. Buahnya memiliki beberapa manfaat salah satunya sebagai obat sariawan karena memiliki kadar vitamin C tinggi. Penelitian ini bertujuan mengidentifikasi dan menentukan nilai parameter spesifik dan non spesifik ekstrak buah dengen (Dillenia serrata Thumb.). Sampel diperoleh dari Kecamatan Malili, Kabupaten Luwu Timur Provinsi Sulawesi Selatan, dimaserasi dengan etanol 96% sebanyak 3 L kemudian dilakukan pengujian parameter spesifik dan non spesifik. Penelitian menunjukkan ekstrak buah dengen (Dillenia serrata Thumb.) memberikan hasil sesuai parameter standar umum ekstrak tumbuhan obat dengan nilai parameter spesifik sebagai berikut: ekstrak berbentuk kental, berwarna coklat pekat kehitaman, berbau khas; kadar senyawa larut dalam air yakni 16,0384%; kadar senyawa larut dalam etanol yakni 16,9811%; positif mengandung senyawa alkaloid, polifenol, flavanoid, terpenoid dan saponin; dan nilai parameter non spesifik sebagai berikut: susut pengeringan yakni 0,0615%; kadar air yakni 3,8052%; kadar abu total yakni 5,0599%, kadar abu tidak larut dalam asam yakni 0,4807%.
Uji Aktivitas Sitotoksik Ekstrak Daun Matoa (Pometia pinnata) dengan Metode BSLT (Brine Shrimp Lethality Test) Rahmawati, Junita Eka; Wati, Aulia; Handayani, Selpida
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.159

Abstract

Matoa plant (Pometia pinnata) is a typical Papuan plant included in the Sapindaceae family which can relieve hypertension and has diuretic, antidiabetic and antioxidant activities. Matoa leaves contain chemical alkaloids, flavonoids, saponins, and steroids. The purpose of this study was to determine the toxic effect and LC50 value of n-hexan extract of matoa leaves against Artemia Salina Leach larvae. Extraction is carried out by maceration method with n-hexane solvent. The n-hexan extract of matoa leaves is prepared in a test solution with concentration variations of 500 ppm, 750 ppm, 1000 ppm, and 1500 ppm. Toxicity testing was carried out using Artemia Salina Leach larvae then the toxic effect of the extract was identified with the percentage of death of Artemia Salina Leach larvae using probit analysis (LC50). The results of this study showed the highest mortality at a concentration of 1500 ppm with the death of 30 larvae. Based on the results of the research conducted, it can be concluded that matoa leaf extract (Pometia pinnata) has a toxic effect on Artemia Salina Leach larvae with a Lethal Concentration value of 50 (LC50) of 509.577 ppm and is included in the toxic category.
Co-Authors Abdul Rasyid, Faradiba Amaliah Dahlia, Andi Aminah Aminah Amran, Farizah Dhaifina Andina, Velda Aulia Wati, Aulia Badu, Nurul Fadillah Fahirah, Jihan Faradiba Hasnaeni Hasnaeni hasnaeni, Hasnaeni Herwin Herwin, Herwin Hossani, Rahni Ida Kurniawati, Ida Indah Pratiwi Majid, Nini Nirmala Mamat Pratama, Mamat Nurliadi, Indah Nurlina Nurlina Putri, Andra Audina Rahmawati, Junita Eka Rais Razak, Rais Rezki Amriati Syarif, Rezki Amriati Risda Waris, Risda Sari, Felisa Ananda Utami, Fadhillah Resky Virsa Handayani Wisdawati Wisdawati, Wisdawati