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All Journal eJournal Kedokteran Indonesia Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia
Eliza Miranda
Departemen Dermatologi Dan Venereologi Fakultas Kedokteran Universitas Indonesia RSUPN Dr. Cipto Mangunkusumo Jakarta
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Telogen effluvium incidence in women wearing hijab compared to non-hijab: A cross-sectional study Sirait, Sondang Pandjaitan; Widaty, Sandra; Legiawati, Lili; Surachmiati Suseno, Lis; Krisanti, Roro Inge Ade; Budianti, Windy Keumala; Miranda, Eliza; Rihatmadja, Rahadi; Oktarina, Caroline; Pandelaki, Paulus Anung Anindita; Situmeang, Irhen
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 2
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Background: Hair loss is a normal experience, but if the amount of hair loss exceeds what is considered normal, it will usually cause anxiety for the patient. In Indonesia, almost every Muslim woman wears a hijab. The hijab is one of many factors believed to cause hair loss. Telogen effluvium (TE) itself is a hair cycle disorder in which the anagen phase terminates prematurely, resulting in diffuse club hair loss without scarring, and TE itself has many risk factors. The purpose of this study was to determine the relationship between the incidence of TE in women who wear hijabs and those who do not. Methods: This cross-sectional study was conducted from August 2019 to April 2021 involving 188 healthy women aged 18 years and over who had not yet reached menopause. In the hijab group, it was determined that they should wear a minimum of 8 hours a day for at least 5 years. The test was carried out on hair that had not been washed using a trichogram, to look for hair characteristics in each group (hijab-wearing and non-hijab-wearing). Analysis of the data obtained was carried out using the Chi-square test and odds ratio. Results: Telogen effluvium was higher in subjects wearing hijab (26.8%) than in subjects who did not wear hijab (18.1%), (p-value 0.040, OR 2.036). Conclusion: There was a significant relationship between TE in women who wear hijab compared to those who do not. Further studies should be conducted in other populations with a larger sample size to confirm these results.
The spectrum of cutaneous manifestations in COVID-19 patients at Dr. Cipto Mangunkusumo Hospital Widaty, Sandra; Menaldi, Sri Linuwih Susetyo Wardhani; Miranda, Eliza; Marissa, Melani; Nilasari, Hanny; Melinda, Thong Felicia; Cornain, Emilina Faradila
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 2
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Background: Cutaneous manifestations are identified in 0.2%–20% of COVID-19 cases, both in adult and pediatric patients. They can occur before, simultaneously with, or after the systemic symptoms of COVID-19. This study aims to analyze the association between cutaneous manifestations, severity, and outcomes of patients with COVID-19. Methods: This observational study was conducted from April 2020 to April 2021 in Dr. Cipto Mangunkusumo Hospital, a referral center for COVID-19 in Jakarta, Indonesia. Medical records were used to collect demographic, clinical, and laboratory data. Results: A total of 0.61% (31/5070) of COVID-19 cases showed cutaneous manifestations, consisting of maculopapular (80.6%), vesicular (16.1%), livedoid (6.4%), pseudo-chilblain (3.2%), and urticarial (3.2%) lesions, with three patients showing more than one cutaneous manifestation. In the present study, only 2,001 out of 5,070 patients were appropriately confirmed to suffer from COVID-19 infection. Multisystem inflammatory syndrome in children (MIS-C) was identified in one out of eleven patients under 21 years old. Laboratory examinations showed an increased neutrophil-to-lymphocyte ratio (NLR), C-reactive protein (CRP), procalcitonin, D-dimer, and creatinine alongside a decreased albumin level. Conclusion: We reported various cutaneous manifestations and diagnostic test results associated with COVID-19. More than one cutaneous manifestations are present in several COVID-19 patients in our study. Several contradictory findings relative to previous publications indicate the necessity of collecting more data regarding the cutaneous manifestation of COVID-19.
Dermoscopy and 30% potassium hydroxide direct examination as diagnostic tools for distal lateral subungual onychomycosis Gaol, Evangelina Lumban; Miranda, Eliza; Sirait, Sondang Pandjaitan
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 2
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Background: Culture and histopathological examination are gold standards for diagnosing onychomycosis. However, these examinations are subject to several limitations. Dermoscopy has the potential to become a promising diagnostic tool for onychomycosis. Direct examination of potassium hydroxide (KOH) also has advantages similar to dermoscopy. Knowing the accuracy of both examinations can help clinical decision-making. Our objectives are to assess the diagnostic value of dermoscopy, KOH examination, and their combination for distal lateral subungual onychomycosis compared to culture or histopathology. Methods: This was a cross-sectional diagnostic study of nails with suspected distal lateral subungual onychomycosis. Sixty nails were included in this study. Results: The sensitivity and specificity of the KOH examination were 89.6% and 66.7%, respectively. On dermoscopy, the sensitivity of jagged-edge-with-spikes, longitudinal striation, and discoloration were 89.6%, 93.8%, and 97.9%, respectively. Only the aurora borealis dermoscopic feature provided good specificity (91.7%). The positive predictive values of these four dermoscopic features were 75.0%–79.7%. Combination with KOH examination increased the positive predictive value of dermoscopy (90.9%–92.7%). Conclusion: Since they were superior in terms of sensitivity, dermoscopy and KOH examinations are good screening tools to determine which suspected onychomycosis cases need further examination. Additionally, an increased positive predictive value was observed when the two examinations were combined. Hence, these procedures can help establish a diagnosis in settings where mycologic examinations are unavailable.
Herpes Zoster Reactivation Following COVID-19 mRNA Vaccination in an Elderly Patient: A Case Report Sarah, Ratu Siti Khadijah; Hapsari, Yari Castiliani; Yusharyahya, Shannaz Nadia; Miranda, Eliza; Edwar, Sarah Qanita
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 9, No. 1
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Background: Latent varicella-zoster virus (VZV) in nerve ganglia may reactivate into herpes zoster infection. The coronavirus disease (COVID-19) vaccine is suspected of triggering VZV reactivation, although the exact cause is unclear. This case report aims to raise awareness of the potential complications induced by the COVID-19 mRNA vaccine, particularly in elderly patients. Case Illustration: A 62-year-old woman complained of itchy and painful unilateral dermatomal herpetiform blisters six days after mRNA COVID-19 vaccination. The vesicle first appeared on the left breast, spreading to the back. The patient has a history of hypertension. After the administration of 800 mg of acyclovir five times a day for seven days, the vesicles dried up, and no new vesicles emerged. Discussion: The incidence of herpes zoster has been widely reported to occur within 5-7 days after the COVID-19 vaccination, mostly due to the mRNA vaccine. The dysregulated cell-mediated immune system may trigger VZV reactivation. The vaccines have been shown to induce a cellular response with increased CD8+ T-cells and T-helper type 1 CD4+ T cells. The VZV-specific CD8+ cells cannot control VZV after the massive shift of naïve CD8+ T-cells in the setting of COVID-19 vaccination. Hypertension is also allegedly the main comorbid factor for herpes zoster reactivation after COVID-19 vaccination. Conclusion: Increased awareness and early recognition of potential COVID-19 vaccine-related complications, especially in elderly individuals with comorbidities, are important for timely management and prevention of further issues.
Co-Authors Aditya Wardhana Anandika Pawitri Andrea, Valerie Cornain, Emilina Faradila Dien, Siphora Edwar, Sarah Qanita Endi Novianto Eyleny Meisyah Fitri Fitri, Eyleny Meisyah Gaol, Evangelina Lumban Githa Rahmayunita Halim, Melissa Hanny Nilasari Hapsari, Yari Castiliani Herwinda Brahmanti Islami, Artini Wijayanti Krisanti, Roro Inge Ade Kusmarinah Bramono Lili Legiawati Lim, Henry W M. Yulianto Listiawan Marissa, Melani Melinda, Thong Felicia Menaldi, Sri Linuwih Susetyo Wardhani Menaldi, Sri Linuwih SW Mufqi Handaru Priyanto Oktarina, Caroline Pandelaki, Paulus Anung Anindita Priyanto, Mufqi Handaru Pusponegoro, Erdina Hardiono D Rahadi Rihatmadja Ratu Siti Khadijah Sarah Rizky, Luddwi Achmad Sandra Widaty Shannaz Nadia Yusharyahya Sirait, Sondang Panjaitan Situmeang, Irhen Sri L. Menaldi Sri Linuwih Menaldi Surachmiati Suseno, Lis Teguh Hopkop Putera Manurung Triana Agustin Windy Keumala Budianti Windy Keumala Budianti Yahya, Sammy Yosi, Ariyati