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All Journal Jurnal Pendidikan Biologi Pendidikan Bahasa Indonesia dan Sastra Best Journal (Biology Education, Sains and Technology) Community Development Journal: Jurnal Pengabdian Masyarakat Pendidikan Bahasa Indonesia dan Sastra (Pendistra) Jurnal Pengabdian Masyarakat Nusantara JBSI: Jurnal Bahasa dan Sastra Indonesia Herbal Medicine Journal Biodik: Jurnal Ilmiah Pendidikan Biologi
Dian Arisetya, Dian
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Public Health Social Sciences Other

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Journal : Herbal Medicine Journal

 1 
Uji Aktivitas Antibakteri Ekstrak Fermentasi Bawang putih tunggal (Allium sativum L.) Terhadap Bakteri Staphylococcus aureus dan Methicillin-resistant Staphylococcus aureus (MRSA) Sapitri, Alfi; Marbun, Eva Diansari; Arisetya, Dian
Herbal Medicine Journal Vol 8 No 1 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i1.152

Abstract

The pathogenicity of S. aureus bacteria is often associated with purulent wound infections in both humans and animals, which is the main cause of pyemia cases. Methicillin-Resistant Staphylococcus aureus (MRSA) is a Staphylococcus aureus bacteria that is resistant or immune to methicillin-type antibiotics and its derivatives. This study aims to see the activity of extracts from single garlic fermentation (Allium sativum L) which have antibacterial effects against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria. This study was conducted at the Pharmacy Laboratory of Sari Mutiara Indonesia University in June-August 2024. This research method was carried out experimentally, the extraction was maceration and the media was tested using MHA to see the bacterial inhibition power. Based on the results of phytochemical screening examinations of single garlic fermentation extracts, it showed the presence of chemical compound groups in the form of Alkaloids, Flavonoids, Tannins, and Saponins. Where the concentration of single garlic fermentation extract is 5%; 10%; 15%. The results of the inhibition test against Staphylococcus aureus bacteria were 9.74 mm; 11.48 mm; 12.19 mm, positive control (chloramphenicol) 12.35 mm. The results of the inhibition test against Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria were 8.49 mm; 10.58 mm, 11.33 mm, positive control (chloramphenicol) 11.42 mm. Ethanol extract from single garlic fermentation has weak antibacterial activity against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria.
Formulasi dan Evaluasi Sediaan Obat Kumur Dari Ekstrak Fermentasi Bawang Lanang (Allium sativum L.) Marbun, Eva Diansari; Sapitri, Alfi; Arisetya, Dian; Thaib, Cut Masyithah; Haliza, Aipak; Purba, Elizabet Kristina; Helmi, Helmi
Herbal Medicine Journal Vol 8 No 1 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i1.153

Abstract

Mouthwash is a dilute concentration of antibacterial solution used to fight oral microbes, fight oral infections, cleansers, to eliminate bad breath, fresh and antiseptic. Mouthwash plays an important role in an individual's oral hygiene, mouthwash helps to relieve symptoms of gingivitis, inflamed gums and can also be relied on to destroy pathogenic bacteria. (Banu & Gayathri, 2016). The purpose of this study was to see if the extract from fermented Bawang Lanang (Allium sativum L) can be formulated into a mouthwash. This research method is an experimental laboratory. By including preparation of materials, sample identification, Making fermented Bawang Lanang, making extracts, extract yields, phytochemical screening, then formulated into a mouthwash. After that, an evaluation of the physical preparation of the mouthwash was carried out (organoleptic test, pH test, viscosity test and stability test). The results of the evaluation of the mouthwash preparation starting from the organoleptic test, pH test did not exceed pH 7, viscosity test of the series was stable for 3 months. Conclusion: Mouthwash preparations containing fermented ethanol extract of male shallots can be used as mouthwash, with good stability.
Buah Pisang barangan (Musa acuminata linn) Sebagai Media Alternatif Perkembangbiakan Bakteri Lubis, Retnita Ernayani; Sapitri, Alfi; Arisetya, Dian; Marbun, Eva Diansari
Herbal Medicine Journal Vol 8 No 1 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i1.155

Abstract

Barangan banana (Musa acuminata linn) has an energy content of 89 calories, 22.84 grams of carbohydrates, 1.09 grams of protein and 0.33 grams of fat. The nutritional content and bioactive substances of barangan bananas have phenolics, anthocyanins and phenols. The purpose of this study was to determine whether barangan bananas can potentially be an alternative medium for bacterial growth. The growth method used in this study was the scratch method, with the calculation of the number of colonies using the TPC (Total Plate Count) method. The results of the study on the scratch method at various concentrations were able to grow optimally on barangan banana-based media at a concentration of 36%. The shorter exponential phase (log) period in the 36% concentration media with a higher cell density than in the 12% concentration media. Conclusion: Barangan banana (Musa acuminata linn) can potentially be an alternative medium for bacterial growth.
Aktivitas Antibakteri Ekstrak Etanol Bulbil Porang (Amophophallus muelleri Blume.) Terhadap Bakteri Staphylococcus aureus dan Streptococcus mutans Sapitri, Alfi; Marbun, Eva Diansari; Arisetya, Dian; Lubis, Retnita Ernayani
Herbal Medicine Journal Vol 8 No 2 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i2.161

Abstract

The porang is a fruit produced by the porang plant which is brownish black in color, oval in shape like a stone and the size is approximately the size of small marbles to large marbles, growing between the stems of the porang plant. This study aimed to determine the activity of the ethanol extract of the porang frog (Amorphophallus muelleri Blume) as an antibacterial against Staphylococcus aureus and Streptococcus mutans bacteria and to determine the chemical compounds contained in the porang frog (Amorphophallus muelleri Blume). Porang frog simplicia powder was extracted in 96% ethanol by maceration. Simplicia powder is screened to determine its phytochemical content. The antibacterial activity test was carried out using the Kirby Bauer method using paper discs against Staphylococcus aureus and Streptococcus mutans bacteria to determine the zone of inhibition. The simplicia results showed that the simplicia frog porang had 6.08% water content, 29.11% water soluble extract, 9.70% ethanol soluble extract, 93.51% total ash content, insoluble ash content in ethanol. acid 91.96%. Simplicia said porang contains alkaloids, flavonoids, and tannins.The ethanol extract of the porang frog (Amorphophallus muelleri Blume) has antibacterial activity against Staphylococcus aureus and Streptococcus mutans bacteria.
Aktivitas Antibakteri Ekstrak Etanol Daun Jengkol (Archidendron pauciflorum Benth.) Terhadap Bakteri Staphylococcus epidermidis dan Pseudomonas aeruginosa Arisetya, Dian; Sapitri, Alfi; Asfianti, Vivi; Lubis, Retnita Ernayani
Herbal Medicine Journal Vol 8 No 2 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i2.162

Abstract

Archidendron pociflorum benth is a nutritious plant that is used as a traditional medicine that is often used by society. Secondary metabolic compounds contained in archidendron pociflorum leaves are alkaloids, flavonoids, tannins and saponin. The purpose of this research is to know the antibacterial activity of the extract of archidendron pociflorum leaf ethanol from the Staphylococcus epidermidis and Pseudomonas areuginosa bacteria. Research conducted experimentally including the collection and processing of archidendron pociflorum leaves. The powder simplisia leaves archidendron pociflorum then be done characteristic and macerated using ethanol 96%. Further extracts of archidendron pociflorum leaf ethanol in the phytochemical screening and carried out test antibacterial activity against Staphylococcus epidermidis and pseudomonas areuginosa bacteria use the diffusion method to make it with disc paper. Results characteristic simplisia of archidendron pociflorum leaves obtained water content of 8.1%, water soluble sari content of 9.49%, soluble pollen content of 7.61%, total ash content 3.80%, ash content of insoluble acid 14.67%. Scining extracts of archidendron pociflorum leaves and simplisia indicate the presence of alkaloid, tannins, saponin, flavonoids. The test results of antibacterial activity indicate that the leaf ethanol extract of the staphylococcus epidermidis bacteria with a concentration of 80%, 60%, 40%, 20% respectively had an obstacle zone of 13.6 mm, 12.3 mm, 11, 4mm and 9.7 mm. While in bacteria pseudomonas areuginosa with a concentration of 80%, 60%, 40%, 20% respectively has a inhibitory zone of 14.3 mm, 13.1 mm, 11.2 mm and 10.3 mm. Archidendron pociflorum leaf ethanol extract has been effective against antibacterial activity with a concentration of 80% against bacteria staphylococcus epidermidis and pseudomonas aureginosa.
Co-Authors Anton Luvi Siahaan Asfianti, Vivi Dwi Priyanti Ely Djulia Gayus Simarmata, Gayus Ginting, Mandike Haliza, Aipak Hasruddin Helmi Helmi Insenalia Sampe Roly Hutagalung Junifer Siregar Lumbangaol, Sudirman T. P Marbun, Eva Diansari Mulriani, Dian Pasaribu, Sunggul Purba, Elizabet Kristina Purba, Yoel Octobe Retnita Ernayani Lubis Risma Hartati, Risma Sapitri, Alfi Siahaan, Rina Devi Romauli Silitonga, Immanuel Doclas Belmondo Simamora, Benjamin A Siti Maimunah Tambunan, Muhammad Iqbal H. Thaib, Cut Masyithah Utama, Rezza Fikrih Zulmawati, Zulmawati