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All Journal Pharmacon Acta Pharmaciae Indonesia : Acta Pharm Indo JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Kesehatan Medika Saintika PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JPP Jurnal Kesehatan Poltekkes Palembang Jurnal Ilmu Kesehatan Jurnal Ners Abdimas Galuh : Jurnal Pengabdian Kepada Masyarakat MAHESA : Malahayati Health Student Journal Indonesian Community Journal Abdi Geomedisains Jurnal Farmasi Sains dan Praktis Prosiding University Research Colloquium Journal of Pharmaceutical and Sciences. Journal of Community Empowerment
Cholisoh, Zakky
Fakultas Farmasi, Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Jurnal Ners

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Gambaran Adverse Drug Reactions (Adrs) Pada Pasien Kanker Payudara yang Mendapatkan Adjuvant Endocrine Therapy (Aet) Tamoxifen dan Faktor-Faktor yang Mempengaruhinya di Rs Swasta Semarang Tahun 2023 Kusumastuti, Maria Siska Triyuniar; Cholisoh, Zakky
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.19330

Abstract

The use of adjuvant endocrine therapy (AET) tamoxifen in the treatment of breast cancer has been associated with adverse drug reactions (ADRs). This study aims to assess the picture of ADRs in breast cancer patients receiving Tamoxifen Adjuvant Endocrine Therapy (AET) and the factors that influence it in Semarang private hospitals. This study was conducted with a cross-sectional design that was analyzed quantitatively and the sampling technique was carried out by purposive sampling. The inclusion criteria are adult breast cancer patients who receive Adjuvant Endocrine Therapy (AET) tamoxifen at least in 1 month, patients are willing to be respondents to fill out questionnaires by signing informed consent. Evaluation of the incidence of ADRs identified by the pharmacist. A total of 87 respondents experienced 18 types of ADRs. The three most common ADR events experienced by patients in the last 7 days were hormonal reactions to painful breasts (25.68%), hot or warm sensations in the upper body (chest, neck, face) (13.51%), vaginal dryness (10.14%). There is an incidence of ADRs in breast cancer patients receiving Adjuvant Endocrine Therapy (AET) tamoxifen. The three most common ADR events experienced by patients in the last 7 days were hormonal reactions to painful breasts (25.68%), hot or warm sensations in the upper body (chest, neck, face) (13.51%), vaginal dryness (10.14%). It is known that age, stage, and consumption of other drugs are not significantly associated with the incidence of ADR.
Co-Authors Adelina Damayanti Amanda Wahyu Kurniawan Ambar Yunita Ambar Yunita Nugraheni Anita Sukmawati Audi Tahta Aurellia Azmi, Rizki Nur Brainandiva Ade Fitria Burhannudin Ichsan Cahya Rahma Utami Damayanti, Adelina Dedi Hanwar Dian Oktianti Dwi Novita Sari Endang Setyaningsih Erindyah Retno Wikantyasning Farida, Rahayu Gita Ayu Pradina Hapsari, Pramudita Mila Hekmah, Laila Nur Heppy Purbasari Hidayah Karuniawati Hidayah, Azzahra Zulfa Nur Husna Fauzia Ika Trisharyanti Dian Kusumowati Irhamadi Malik Khoirunnisa Khoirunnisa Kusumastuti, Maria Siska Triyuniar Kusumawardani, Mia Laila Nur Hekmah Larasati, Arindra Luluk Ria Rakhma Malik, Irhamadi Mar’ah, Siti Sitatul Mika Tri Kumala Swandari, Mika Tri Kumala Muhammad Ikhsan Al Af Ghani Oktasari, Solikhah Rosvita Pradina, Gita Ayu Pramudita Mila Hapsari Putri, Citra Agustin Ananda Putri, Nabilla Andasari Rajali, Ahmad Ramadhani, Renita Nur Ramdani, Tasya Eka Refsya Azanti Putri Reiza, Zenita Rima Munawaroh Riswanto, Muhammad Imam Rizka Mulya Miranti Rizki Nur Azmi Rohmah, Siti Alfiatur Rosi Hayyu Anjani Rukmini, Aulia Sally Astya Utami Sania Nayasari Khoirunnisa Sari, Dwi Novita Setiaji, Muh Maskur Setiawan, Abdul Aziz Setiawardani, Maria Fitri Setyo Nurwaini Siti Alfiatur Rohmah Suryaman, Sulistia Syah, Dhafina Salsabila Tanti Azizah Tanti Azizah Utami, Sally Astya Utaminingsih, Esthi Wahyu Utami, Wahyu Wahyudi, Afiv Wikantyasning, Erindyah R. Yuka Aulia Rahma Zaenab Zaenab Zaenab Zulfa, Farah Qanitha