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All Journal METAMORFOSA Journal of Biological Sciences Jurnal Kreativitas PKM Jurnal Riset Kesehatan Nasional LOSARI: Jurnal Pengabdian Kepada Masyarakat MAHESA : Malahayati Health Student Journal Jurnal Pijar MIPA JRKN Journal of Health and Nutrition Research Jurnal Pengabdian West Science Jurnal Pengabdian Kepada Masyarakat Itekes Bali Jurnal Pengabdian Masyarakat Sundaram Jurnal Medika Usada Berita Biologi Folia Medica Indonesiana
Ni Wayan Sukma Antari
Institut Teknologi Dan Kesehatan Bali
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Other

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Formulation and Physical Stability Aromatherapy Medicated Oil of Red Ginger (Zingiber officinale var rubrum) Pramana, I Kadek Bagus Ari; Dira, Made Asmarani; Damayanti, Ida Ayu Manik; Antari, Ni Wayan Sukma
Jurnal Pijar Mipa Vol. 19 No. 4 (2024): July 2024
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v19i4.6934

Abstract

Aromatherapy products for health relax the body, refresh the mind, and act as a placebo in treating diseases. The more modern aromatherapy medicated oil innovation has high competitiveness in its distinctive aroma and packaging without reducing pharmacological effectiveness. One source of essential oil is red ginger (Zingiber officinale var rubrum), which has pharmacological effects such as antioxidant, anti-inflammatory, analgesic, and anti-carcinogenic. This research aims to prepare, formulate, perform a physical evaluation, and conduct hedonic testing of red ginger aromatherapy medicated oil. This research is experimental research with a posttest group design research design. The physical evaluation results, including organoleptic tests on color, showed that preparations F0 to F3 were precise, yellow +, yellow ++, and yellow +++, respectively. The aroma shows preparations F0 to F3, respectively, the smell of menthol to the typical aroma of red ginger (strong), and the texture F0 to F3 shows a liquid texture. The homogeneity test showed that preparations F0 to F3 were homogeneous. The pH test showed that the pH value of the preparation ranged between pH 5.5 and 6.2 for preparations F0 to F3. This study concluded that the red ginger aromatherapy medicated oil formulation with a concentration of 2%, 4%, and 6% has good physical quality.
Gambaran Histologi Ovarium dan Fluktuasi Hormon Estrogen pada Mencit Betina (Mus musculus L.) yang diberi Ekstrak Buah Zuriat (Hyphaene thebaica) sebagai Antioksidan Alami Antari, Ni Wayan Sukma; Damayanti, Ida Ayu Manik; Padmiswari, anak agung istri mas; Harditya, Kadek Buja
MAHESA : Malahayati Health Student Journal Vol 3, No 4 (2023): Volume 3 Nomor 4 (2023)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.134 KB) | DOI: 10.33024/mahesa.v3i4.10260

Abstract

ABSTRACT Hyphaene thebaica belongs to the Palmae family which is often referred to as zuriat fruit. Hyphaene thebaica has properties as an antimicrobial, antioxidant, and antidiabetic. This study aims to determine the effect of zuriat extract on the number of follicles on the ovaries in female mice (Mus musculus) given exposure to cigarette smoke. This research have conducted for 6 months from January to June 2021. This type of research was pure experimental (true experimental) with a post test only control group design approach. This study was conducted by giving zuriat fruit extract as treatment for 42 days to female mice. The sample in this study was calculated using the Federer formula (1991). After treatment for 42 days, observations were made on ovarian histology which included: a. primary follicles, b. secondary follicles c. tertiary follicles and estrogen hormone. The research data were processed using a computer statistical program (SPSS 22.0 for Windows) using the OneWay Anova test. The results showed that the administration of zuriat fruit extract can increase the number of follicles in the ovary and increase estrogen hormone.  Keywords: (Mus musculus L.), free radicals, smoking, Hyphaene thebaica  ABSTRAK Hyphaene thebaica termasuk dalam keluarga Palmae yang sering disebut dengan buah zuriat. Hyphaene thebaica memiliki khasiat sebagai antimikroba, antioksidan, dan antidiabetes Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak zuriat terhadap jumlah folikel pada ovarium pada mencit betina (Mus musculus) yang diberi paparan asap rokok. Penelitian ini akan dilaksanakan selama 6 bulan pada bulan Januari sampai dengan Juni 2021. Jenis penelitian ini adalah eksperimental murni (true experimental) dengan pendekatan post test only control group design. Penelitian ini dilakukan dengan memberikan ekstrak buah zuriat sebagai perlakuan selama 42 hari pada mencit betina. Sampel yang akan digunakan dalam penelitian ini dihitung menggunakan rumus Federer (1991). Setelah dilakukan pemberian perlakuan selama 42 hari selanjutnya dilakukan pengamatan pada histologi ovarium yang meliputi: a. folikel primer, b. folikel sekunder c. folikel tersier dan hormone estrogen. Data hasil penelitian diolah menggunakan program statistik komputer (SPSS 22.0 for Windows) dengan menggunakan uji One Way Anova. Hasil penelitian menunjukan bahwa pemberian ekstrak buah zuriat dapat meningkatkan jumlah folikel pada ovarium dan meningkatkan hormone estrogen. Kata Kunci: (Mus musculus L.), Radikal Bebas, Rokok, Hyphaene Thebaica
Edukasi Pola Makan Sehat dalam Upaya Pengendalian Kadar Gula Darah pada Masa Pandemi COVID-19 Damayanti, Ida Ayu Manik; Antari, Ni Wayan Sukma; Lumbantobing, Gita Vidya Natalia; Tohir, Wa. Aniyda M.
LOSARI: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 2 (2021): Desember 2021
Publisher : LOSARI DIGITAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53860/losari.v3i2.47

Abstract

Diabetes mellitus (DM) merupakan jenis penyakit menahun yang akan diderita seumur hidup oleh penderitanya bila tidak mendapat penanganan secara baik. Komplikasi yang ditimbulkan menjadikan diabetes mellitus sebagai penyakit penyerta yang menyebabkan tingginya angka keparahan dan kematian pada masa pandemi covid-19 yang terjadi  hampir di seluruh negara di dunia. Salah satu kota yang terdapat kasus ini adalah Kota Denpasar tepatnya wilayah Denpasar Selatan. Angka kejadian hipertensi serta DM di kelurahan Denpasar Selatan, didapatkan merupakan penyakit yang cukup tinggi diantara penyakit tidak menular lainnya. Berdasarkan permasalahan tersebut perlu dilakukan upaya preventif untuk menurunkan risiko komplikasi yang tinggi pada penderita penyakit tidak menular seperti diabetes mellitus. Hal ini dilakukan bertujuan untuk meningkatkan kesadaran kepada masyarakat di kelurahan Denpasar Selatan sehingga dilakukan edukasi mengenai pola asupan makanan sehat dan seimbang sebagai salah satu upaya pencegahan dan pengendalian kadar gula darah pada masa pandemi Covid-19. Metode pelaksanaan kegiatan diawali dengan tahap persiapan selanjutnya pelaksanaan dengan memberi edukasi berupa leaflet serta tanya jawab lisan dan diakhiri dengan evaluasi kepada masyarakat. Berdasarkan hasil kegiatan diketahui adanya peningkatan sebesar 50% terhadap pengetahuan responden tentang pola makan sehat dalam upaya pengendalian diabetes mellitus di masa pandemi covid-19.
POTENSI EKSTRAK KULIT ANGGUR BALI (Vitis vinifera L. Var. Alphonso Lavallee) TERHADAP BERAT BADAN: SKRINING FITOKIMIA DAN STUDI IN VIVO Damayanti, Ida Ayu Manik; Antari, Ni Wayan Sukma; Megayanti, Sri Dewi
Berita Biologi Vol 24 No 1 (2025): Berita Biologi
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/berita_biologi.2025.9564

Abstract

Sebanyak 51,7% penduduk Indonesia mengonsumsi makanan berlemak/berkolesterol/gorengan sebanyak 1-6 kali per minggu. Pada umumnya masyarakat mengonsumsi beberapa obat sintetik untuk mengatasi masalah berat badan dengan efek samping yang sangat mungkin terjadi. Dalam upaya mengatasi hal tersebut, penelitian mengenai potensi bahan alami sebagai agen penurun berat badan menjadi sangat relevan. Salah satu bahan alami yang menarik perhatian adalah kulit anggur Bali (Vitis vinifera L. Var. Alphonso Lavallee). Penelitian ini bertujuan untuk mengeksplorasi potensi ekstrak kulit anggur Bali dalam menurunkan berat badan melalui skrining fitokimia dan studi in vivo dengan memanfaatkan sumber daya lokal dalam pengembangan strategi penanganan penurunan berat badan yang efektif. Design penelitian yang digunakan adalah true experimental study dengan posttest only control group design. Kelompok yang digunakan yaitu kontrol negative, kontrol positif, P1 (100 mg/kgBB), P2 (250 mg/kgBB), dan P3 (500 mg/kgBB). Skrining fitokimia ekstrak kulit anggur Bali menunjukkan bahwa kulit anggur Bali mengandung senyawa flavonoid, fenol, alkaloid, tanin dan terpenoid. Penelitian ini menunjukkan bahwa ekstrak kulit anggur Bali (Vitis vinifera L. Var. Alphonso Lavallee) memiliki potensi signifikan dalam menurunkan berat badan mencit yang diberikan pakan tinggi lemak. Kelompok P3 menunjukkan total penurunan paling tinggi sebesar 2,4% dari hari ke-0 hingga hari ke-21dibandingkan P1 dan P2.  
Provision of arak bali reduces spermatozoa quality of white rats (rattus norvegicus) Antari, Ni Wayan Sukma; Hayati, Alfiah; Winarni, Dwi
Folia Medica Indonesiana Vol. 52, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aimed to determine the effect of arak bali on the quality of spermatozoa include morphology, motility, viability, membrane integrity of spermatozoa rat (Rattus norvegicus). The study was conducted in two phases: the first phase of the deployment of questionnaires conducted in five districts in Bali to determine the type and frequency of arak bali consumption and phase II made arak bali giving treatment in experimental animals. This study used 24 male rats (170-200 grams), divided into four groups: one control and three treatments (by arak bali containing 40% alcohol as much as 0.1 and 0.5 mL and 0.1 mL much alcohol synthesis, for 45 days. the results showed that of the five districts in Bali, most people consume arak bali commercial and most of the frequency of consumption of the week more than one bottle (350 mL). the provision of arak bali in experimental animals, degrade the quality (morphology, motility, viability, membrane integrity), the greater the volume given declining spermatozoa quality.
Effects of Arak Bali Administration on Spermatozoa DNA Fragmentation and Testosterone Level of Rats (Rattus norvegicus) Hayati, Alfiah; Winarni, Dwi; Antari, Ni Wayan Sukma; Resita, Inne Ninda; Fauziah, Erlyn Nurul
Folia Medica Indonesiana Vol. 54, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aimed to determine the effects of arak bali on the fragmentation of spermatozoa and testosterone in rats (Rattus norvegicus). This study used 24 rats (170-200 g), divided into four groups: one control and three treatments (receiving arak bali containing 40% alcohol as much as 0.1 and 0.5 mL and synthetic alcohol (40%) as much as 0.1 mL, for 45 days). The observation of DNA fragmentation was done using acridine orange staining and the measurement of testosterone level used ELISA method. The results showed that the provision of arak bali in experimental animals increased the occurrence of spermatozoa DNA fragmentation. The higher the volume of arak bali given, the higher the fragmentation of spermatozoa DNA. The administration of arak bali also decreased testosterone level. The higher the volume of arak bali given, the lower the rats' testosterone level.
Sinergi Komunitas Tani dan Kader Posyandu melalui Karangasem Gemilang: Gerakan Milenial Lawan Anemia dan Gizi Buruk Berbasis Pangan Fungsional Darmayanti, Putu Ayu Ratna; Antari, Ni Wayan Sukma; Widnyani, Ida Ayu Putu Ary
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 9, No 3 (2026): Volume 9 Nomor 3 (2026)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v9i3.24410

Abstract

ABSTRAK Desa Tianyar di Kabupaten Karangasem memiliki potensi mangga dan jambu mete yang belum diolah optimal serta menghadapi masalah anemia dan gizi buruk tinggi. Melalui program PM-BEM 2025, sinergi Kelompok Tani Taman Sari dan kader posyandu dilakukan untuk mengolah potensi lokal menjadi pangan fungsional Kukis Mangga Mete dan Granola Mangga Mete guna meningkatkan ekonomi dan kesehatan masyarakat, mewujudkan Karangasem GEMILANG yang sehat, produktif, dan berdaya saing. Memberdayakan masyarakat Desa Tianyar melalui sinergi Kelompok Tani Taman Sari dan kader posyandu dalam mengolah potensi lokal mangga dan mete menjadi produk pangan fungsional Kukis Mangga Mete dan Granola Mangga Mete guna meningkatkan nilai ekonomi hasil tani serta mendukung pencegahan anemia dan gizi buruk di Kabupaten Karangasem. Program dilaksanakan dengan pendekatan edukatif-partisipatif melalui observasi awal dan FGD, edukasi gizi dan pangan fungsional, pelatihan produksi olahan mangga–mete, diskusi kelompok, serta evaluasi melalui pre–post test dan observasi praktik. Program Karangasem GEMILANG meningkatkan pengetahuan peserta tentang pangan fungsional dari 6,5% menjadi 85,2%, serta keterampilan produksi, pengemasan, dan pemasaran produk MangMete Cookies dan MangMete Bar mencapai lebih dari 80%. Sinergi kelompok tani dan kader posyandu efektif memberdayakan masyarakat dalam pengolahan pangan lokal berbasis mangga dan mete, meningkatkan ekonomi desa, serta mendukung pencegahan anemia dan gizi buruk di Kabupaten Karangasem. Kata Kunci: Anemia, Gizi Buruk, Pangan Fungsional, Mangga, Mete.  ABSTRACT Tianyar Village in Karangasem Regency has great potential in mango and cashew cultivation; however, these local resources have not been optimally processed, while the community faces high rates of anemia and malnutrition. Through the PM-BEM 2025 program, a synergy between the Taman Sari Farmers Group and Posyandu health cadres is established to transform local agricultural products into functional foods Mango Cashew Cookies (MangMete Cookies) and Mango Cashew Granola Bars (MangMete Bars) aimed at improving both the community’s economy and health, realizing Karangasem GEMILANG as a healthy, productive, and competitive region. To empower the community of Tianyar Village through collaboration between the Taman Sari Farmers Group and Posyandu cadres in processing local mango and cashew resources into functional food products that enhance agricultural economic value and support anemia and malnutrition prevention in Karangasem Regency. The program was carried out using an educative–participatory approach through initial observation and FGD, nutrition and functional food education, training on mango–cashew product processing, group discussions, and evaluation through pre–post tests and practice observations. The Karangasem GEMILANG program increased participants’ knowledge of functional foods from 6.5% to 85.2%, while skills in production, packaging, and marketing of MangMete Cookies and MangMete Bars improved to over 80%. The synergy between farmer groups and posyandu cadres effectively empowered the community in processing local mango and cashew-based functional foods, improving the village economy and supporting anemia and malnutrition prevention in Karangasem Regency. Keywords: Anemia, Malnutrition, Functional Food, Mango, Cashew. 
The Potential of Binahong Leaf (Anredera cordifolia) Ethanol Extract on Male Fertility in Mice Exposed to E-Cigarette Smoke Widianti, I Gusti Ayu; Wardana, Nyoman Gede; Widhiartini, Ida Ayu Alit; Satriyasa, Bagus Komang; Antari, Ni Wayan Sukma; Pratiwi, Made Sindy Astri
Journal of Health and Nutrition Research Vol. 5 No. 1 (2026)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v5i1.1055

Abstract

Binahong leaf is known for its strong ability to prevent oxidation due to its active flavonoid compounds. Exposure to electronic cigarette smoke can increase reactive oxygen species (ROS), as a contributing factor to infertility. This study aims to identify the potential of Binahong leaf (Anredera cordifolia) ethanol extract on testosterone levels and spermatogenic cells in adult mice (Mus musculus) exposed to electronic cigarette smoke. A post-test control group design was used, with 28 male Balb/c mice allocated to four groups. The control group received 0.3% CMC, while the three treatment groups were administered Binahong leaf ethanol at doses of 50, 100, and 200 mg/kg body weight, in a volume of 0.1 ml orally each evening for 35 days. All mice were exposed to an electronic cigarette containing 6 mg of nicotine for 20 minutes. On day 36, blood samples were obtained to measure testosterone levels via ELISA. Testicular tissue was observed using Hematoxylin-Eosin staining. A marked elevation in testosterone concentrations and spermatogenic cell count was observed in the group treated with 50 mg/kg BW of Binahong leaf ethanol extract in contrast to the control group (p = 0.014 and 0.008, respectively). Higher doses reduced testosterone/spermatogenesis compared to the optimal dose, potentially implying a toxic or inhibitory effect. Binahong leaf ethanol extract administered at 50 mg/kg BW is effective in increasing testosterone levels and spermatogenic cells in adult mice (Mus musculus) exposed to electronic cigarette smoke.
Co-Authors A.A.S. A. Sukmaningsih AA Istri Mas Padmiswari Adiana, I Nengah Alfiah Hayati Aristadewi, Ida Ayu Mas Artha, I Wayan Oktapratama Bagus Komang Satriyasa Deni Redita, I Komang Dharmapatni , Ni Wayan Kesari Dira, Made Asmarani Dwi Arymbhi Sanjaya Dwi Winarni Erlyn Nurul Fauziah Fauziah, Erlyn Nurul Gandamayu, Ida Bagus Maha Gede Surya Indrawan I GEDE PUTU DARMA SUYASA I Made Bayu Jaya Kusuma I.A.A. Widhiartini Ida Ayu Manik Damayanti Ida Bagus Separsa Kusuma Inne Ninda Resita Kadek Ayu Ananda Maharini Kadek Buja Harditya Lumbantobing, Gita Vidya Natalia Mas Aristadewi, Ida Ayu Nadya Treesna Wulansari Ni Kadek Sutini Ni Wayan Desi Bintari Ni Wayan Kesari Dharmapatni Nyoman Eta Risnawati Padmiswari, A.A. Istri Mas Pramana, I Kadek Bagus Ari Pratiwi, Made Sindy Astri Putu Ayu Ratna Darmayanti Resita, Inne Ninda Sri Dewi Megayanti Sri Dewi Megayanti Strisanti, Ida Ayu Suptika Sutrisna, Putu Gede Suweca, I Gede Tohir, Wa. Aniyda M. Wardana, Nyoman Gede Wicaksana, IGA Tresna Widianti, I Gusti Ayu Widiatmaja, Gusti Panji Widnyani, Ida Ayu Putu Ary Widyas Pranata, Gst. Kade Adi