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All Journal Jurnal Pengolahan Hasil Perikanan Indonesia Pharmaciana: Jurnal Kefarmasian Jurnal Ilmu Kefarmasian Indonesia Jurnal Ilmiah Pharmacy Indonesian Journal of Health Science Jurnal Abdi Masyarakat Kita JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA Journal of Community Service Jurnal Pharmacopoeia Eastasouth Journal of Impactive Community Services Bencoolen Journal of Pharmacy
Dwi Kurnia Putri
Prodi D-III Farmasi, FMIPA, Universitas Bengkulu, Bengkulu
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Menjaga Kadar Kolesterol dan Tekanan Darah Untuk Kesehatan Jantung Dengan Konsumsi Minuman Herbal Teh Hijau Annisa, Rully; Tania, Marta; Kurnia, Dwi
JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA Vol 2 No 3 (2023): Juli
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jipmi.v2i3.131

Abstract

Latar belakang: Penyakit jantung koroner adalah suatu penyakit yang disebabkan oleh penyempitan pembuluh darah arteri koroner jantung. Hal ini terjadi karena Tinggi nya kadar kolesterol dapat menyebabkan aterosklerosis pada pembuluh darah Akibat dari penyempitan pembuluh darah tersebut aliran darah ke jantung akan kekurangan oksigen yang dapat menimbulkan gejala nyeri dada yang merupakan gejala khas penyakit jantung koroner. Penyakit kardiovaskuler termasuk penyakit jantung yang dapat menyebabkan kematian tertinggi di dunia. Sebuah riset menunjukkan bahwa konsumsi Teh hijau dapat menurunkan kolesterol total dan kolesterol jahat. Selain itu, Teh hijau juga mengandung asam fenolik, yang dapat menurunkan risiko terjadinya penyakit jantung koroner. Tujuan: Program Pengabdian Masyarakat ini bertujuan untuk memberikan pengetahuan tentang Penyakit jantung koroner dan faktor penyebabnya diantaranya peningkatan kolesterol dan tekanan darah; melakukan pemeriksaan kadar kolesterol dan tekanan darah selanjutnya akan diberikan terapi pemberian teh hijau. Metode: Metode yang digunakan adalah sosialisasi dan intervensi pemberian terapi herbal teh hijau yang dapat diseduh dengan air panas dengan suhu 80-90°C lalu diamkan sejenak sampai teh menjadi hangat dan diminum hingga habis. Teh hijau dapat dikonsumsi sebanyak 3-4 kali sehari dan sebaiknya tidak mencampur dengan bahan lain seperti gula atau susu dan pengukuran kolesterol dan tekanan darah dengan pre-test dan post-test. Selanjutnya  Data dianalisis menggunakan paired T-test. Hasil: Didapatkan perbedaan signifikan perubahan kadar kolesterol dan nilai tekanan darah sebelum dan setelah intervensi (p=0,000). Kesimpulan: Pemberian terapi herbal menggunakan teh hijau dapat menurunkan kadar kolesterol dan tekanan darah tinggi. Kata kunci: kolesterol, penyuluhan, teh hijau, tekanan darah tinggi, terapi herbal __________________________________________________________________________________________ Abstract Background: Coronary heart disease is caused by the narrowing of the coronary arteries of the heart. It happens because high cholesterol levels can cause atherosclerosis in blood vessels. The result of the narrowing of these blood vessels, and blood flow to the heart will deprive of oxygen which can cause symptoms of chest pain is a typical symptom of coronary heart disease. Cardiovascular diseases, including heart disease, can cause the highest death in the world. Research shows that consumption of green tea can lower total cholesterol and bad cholesterol. In addition, green tea also contains phenolic acids, which can reduce the risk of coronary heart disease. Objective: This Community Service Program aims to provide knowledge about coronary heart disease and its causative factors, including increased cholesterol and blood pressure; Checking cholesterol levels and blood pressure will then be given green tea therapy. Method: The method used is socialization and intervention in the provision of green tea herbal therapy can brew with hot water at a temperature of 80-90°C, then let stand for a while until the tea becomes warm, and drink it until it runs out. Green tea can be consumed 3-4 times a day and should not mix with other ingredients such as sugar or milk and cholesterol and blood pressure measurements with pre-test and post-test. Furthermore, data were analyzed using paired T-test. Result: Results: There were significant differences in changes in cholesterol levels and blood pressure values before and after the intervention (p=0.000). Conclusion: Giving herbal therapy using green tea can reduce cholesterol levels and high blood pressure. Keywords: cholesterol, counseling, green tea, high blood pressure, herbal therapy
Ethanolic extract of Parkia speciosa Hassk leaves innovation of gastroretentive tablet: standardization and optimization Nurfitriyana, Nurfitriyana; Fitriya, Fitriya; Fithri, Najma Annuria; Putri, Dwi Kurnia; Lestari, Siti Marwah; Waluyo, Dyah Ayuwati; Syarif, Hardiyanti
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1461

Abstract

Parkia speciosa ethanol leaves extract contains flavonoid, tannin, and terpen as ulcus peptic remedy. These compounds exhibit limited activity in the stomach due to the short gastric residence time following oral administration. The formulation of gastroretentive tablets can overcome this limitation. This research aims to control the prolonged release of drugs in the stomach to increase bioavailability and characterize the ethanol leaves extract. Extraction was carried out by maceration using ethanol, followed by standardization based on specific and non-specific parameters extract. Gastroretentive tablet was formulated with combination of HPMC-K4M and chitosan using factorial design 22. Effects of compositional factors and their interactions on gastroretentive tablet was observed on hardness, friability, floating lag/duration time, swelling index, and mucoadhesive time. Results standardization extract showed that extract met the required criteria for both specific parameters (organoleptic properties and phytochemical screening) and non-specific parameters (moisture content, loss on drying, water/ethanol-soluble extract content). Based on with DX®10 analysis, the optimum formulation was achieved with 20.25% of HPMC-K4M and 10.26% of chitosan. The analysis of the optimum formulation characteristics was as follows: friability (0.22%), hardness (29.53 N), mucoadhesive time (22.86 hours), floating lag/duration time (27.54 minutes; 12 hours), and swelling index (312.82%). Result revealed that gastroretentive tablets formulated with ethanol extract of Parkia speciosa leaves improve gastric residence duration and promote better bioavailability.
Co-Authors . Iskandarsyah Annisa, Rully Armelia, Suci Delia Komala Sari, Delia Komala Devi Maulina Dia Septiani Dian Handayani Dwi Citra Septiana Dyah Ayuwati Waluyo Effionora Anwar Evi Maryanti Fitriya, Fitriya Ginanjar Pratama Ikhsan Ikhsan Itok Dwi Kurniawan Kurniatul Hasanah Martinus, Martinus Milda Rianty Lakoan Muhammad Arifin Mulia, Putri Myran Nur Hinsany Najma Annuria Fithri, Najma Annuria Novi Yantih Nurfitriyana Nurfitriyana Nurfitriyana Nurfitriyana Oky Hermansyah perma sari, rose intan Riana Versita Rini Yanuarti Rose Intan Perma, Sari Sakinah Haryati Sarmubella, Deka SEPTI WULANDARI Siti Marwah Lestari Suci Rahmawati, Suci Syarif, Hardiyanti Tania, Marta Tri Danang Kurniawan Wirahmi, Nori