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Tohap Simangunsong
Universitas Jenderal Soedirman
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Quorum Sensing Inhibition pada Pembetukan Biofilm Salmonella typhi dengan Ekstrak Daun Cincau Hijau (Cyclea barbata Miers) Anjaini, Jefri; Simangunsong, Tohap; Irawan, Hery
Jurnal Biologi Tropis Vol. 24 No. 2 (2024): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2.7232

Abstract

Salmonella is one example of bacteria that can contaminate fishery products. It is one of the bacteria that most commonly infects people through contaminated food and drink. One management to reduce Salmonella in fishery products is using Biofilm. The biofilm mechanism formed from Salmonella typhi type bacteria can be inhibited from several intervention strategies that are able to disrupt and prevent biofilm formation. Green grass jelly leaf extract has antibacterial activity against S. typhi which is indicated by the formation of an inhibition zone due to the activity of flavonoid compounds. denaturing proteins and damaging bacterial cell membranes, flavonoids can also function as antibacterials by forming complex compounds that attack extrinsic proteins and inhibit biofilm formation by inhibiting the expression of icaA and icaD genes. flavonoids form complex compounds against extracellular proteins, which disrupt the integrity of the bacterial cell membrane. It does so by denaturing bacterial cell proteins and damaging the cell membrane beyond repair.
Co-Authors Akhhila, Nilta Any Kurniawati, Any Cahyo, Tri Nur Dewi Nugrayani Dhama, Mei Arya Ekasanti, Anandita Emyliana Listyowati Hamdan Syakuri Hendrayana Hendrayana, Hendrayana Hery Irawan Hery Irawan, Hery Jefri Anjaini Liu, Chun-Hung Mahardhika Nur Permatasari MOHAMAD FADJAR Nurchamidah Prihatiningsih, Isnaini Purnama Sukardi Putra, Muhammad Rafi Prisada Ratnaningsih, Hanim Rahayuani Rose Dewi Saputra, Muhammad Sahrul Dwi Sesilia Rani Samudra Situmorang, Nurbaity Soedibya, Petrus Hary Tjahja Tjahjo Winanto, Tjahjo Widhiatmoko Herry Purnomo Yusup, Dandi Diana