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All Journal VALENSI Indonesian Journal of Applied Sciences STOMATOGNATIC- Jurnal Kedokteran Gigi Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Dentino: Jurnal Kedokteran Gigi Chimica et Natura Acta ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemistry B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah Jurnal Kreativitas PKM Jurnal Review Pendidikan dan Pengajaran (JRPP) JPP Jurnal Kesehatan Poltekkes Palembang Indonesia Berdaya Jurnal Pengabdian Masyarakat Kebidanan Jurnal Kesehatan Gigi dan Mulut (JKGM) Denta: Jurnal Kedokteran Gigi Indonesian Journal of Dentistry Molekul: Jurnal Ilmiah Kimia Prosiding Seminar Kesehatan Masyarakat
Risyandi Anwar
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Effectiveness of Java Chili Extract (Piper retrofractum Vahl.) to Leukocyte Reduction on Wistar Rats with Traumatic Ulcers Rizky Nurhidayah; Risyandi Anwar; Lisa Oktaviana Mayasari
Denta Journal Kedokteran Gigi Vol 13 No 2 (2019): Agustus
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Abstract

Background: Oral traumatic ulcer is an ulcerative lesion of the oral mucosa caused by trauma. The prevalence of traumatic ulcers is quite high between the other oral lesions. Handling traumatic ulcer use corticosteroids that have the effect of increase the growth of Candida sp. in the oral cavity (candidiasis). Objective: To determine the effect of Java chili extract (Piper retrofractum Vahl.) on leukocyte reduction in Wistar rats with traumatic ulcer. Methods: This is experimental laboratory study with pre and post test with a control group design. The research sample using 20 male Wistar rats, weight ±150 grams, 2-3 months old, divided into 4 treatment groups, (K1) group with untreated ulcers, (K2) rats with ulcers treated with iodine, (K3) rats with ulcers treated with java chili extract 50%, (K4) rats with ulcers treated with java chili extract 100%.The research was analyzed by different test with dependent sample t test. Results: The results showed a value of p <0.05 for all comparisons between the two groups showed that there were differences between the two groups compared have a significant difference in the number of leukocytes so it was known that Java chili extract decreased the number of leukocytes in Wistar rats with traumatic ulcers. Conclusion: Java chili extract (Piper retrofractum Vahl.) was effective in decreased the number of leukocytes in Wistar rats with traumatic ulcers.
Co-Authors Ace Tatang Hidayat Al Arofatus Naini Al Arofatus Naini Amiza Zam, Syarifah Nova Anisdyasarathi, Fitri Anjari, Intan Hawina Aprillia, Zita Arlette Setiawan Arlette Setiawan Arlette Setiawan Arlette Setiawan Arlette Setiawan Arlette Suzy Puspa Pertiwi Asti, Salma Mei Darwati Darwati Delia Ilfani Desi Harneti Desi Harneti Putri Huspa Deviana Adinda Nurfatimah Dewi, Anisa Candra Erina Hilmayanti Etny Dyah Harniati Faizah Maira Farabi, Kindi Faridia Puspita Lestari Febriyani, Ita Hadi Kuncoro Intan Hawina Anjari Jayanti, Lira Wiet Khalijah Awang Kindi Farabi Kindi Farabi Lilis Siti Aisyah Lisa Oktaviana Mayasari Mastura, Nurul Izzah Mayasari, Lisa Oktaviana Mohamad Nurul Azmi Muhamad Nurul Azmi Naini, Al Arofatus Nikmaturrizqi, Nada Nisma Dinastiti Nisma Dinastiti Nurhidayah, Rizky Nurlelasari Nurlelasari Nurlelasari Nurlelasari Pebrian Diki Prestya Prajarini, Megawati Puspito Ratih Hardhani Putri, Ghesta Alifka Rachmawati, Ika Rani Maharani Rani Maharani Ratna Sulistyorini, Ratna Rizky Nurhidayah Samuel San Parulian Sarni Sayono Sekarningrum, Galih Prawesty Ayu Sinaga, Siska Elisahbet Siti Aminah Sofa Fajriah Steffi Triany Arnov Suaeni Kurnia Wirda Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Sutiyono, Triagus Nursasongko Tri Mayanti Tri Mayanti Tripermata, Anita Novia Tyas Nurfadlilah Amaliah Unang Supratman Vidia Afina Nuraini Yenny Febriani Yun Yoshihito Shiono