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Activity and Characterization of ZnO Nanoparticles from Ethanol Extract of Plantago major L. as Antibacterial against Propionibacterium acnes I Kadek Sudartayasa; Risyandi Anwar; Maya Dian Rakhmawatie
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 3 (2025): J Sains Farm Klin 12(3), December 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.3.226-235.2025

Abstract

Acne infections are common in tropical regions such as Indonesia and are mainly caused by Propionibacterium acnes. Long-term use of antibiotics for acne treatment may lead to bacterial resistance, highlighting the need for safer natural antibacterial alternatives. Ethanol extract of broadleaf (Plantago major L.) has been reported to exhibit antibacterial activity, which can be enhanced through the application of nanotechnology in the form of zinc oxide nanoparticles (ZnO-NPs). Therefore, this study aims to synthesize and evaluate the antibacterial activity of ZnO-NPs derived from ethanol extract of broadleaf against P. acnes. The broadleaf extract was obtained through maceration with 96% ethanol, and ZnO-NPs were prepared by a precipitation method using zinc nitrate and zinc acetate precursors. The disc diffusion test results showed that 20 mg of ZnO-NPs acetate from broadleaf extract had strong antibacterial activity, with an inhibition zone of 18.11 ± 0.10 mm. The minimum inhibitory concentration of ZnO-NPs acetate from broadleaf extract is 0.078 mg/mL. The morphological characterization of ZnO-NPs acetate from broadleaf extract using Scanning Electron Microscopy-Energy Dispersive X-Ray (SEM-EDX) show a uniform granular particle shape with a size range of 200-228 nm. Based on the research results, the ZnO-NPs acetate from ethanolic extract of broadleaf has the potential to be an effective topical antibacterial alternative for treating acne infections. Based on these findings, ZnO-NPs synthesized from ethanol extract of broadleaf are expected to enhance antibacterial effectiveness and have potential as a safer and more effective topical antibacterial alternative for acne treatment
Hubungan Pengetahuan tentang Kebersihan Rongga Mulut dan Perilaku Menggosok Gigi dengan Status Kebersihan Rongga Mulut pada Santri Pondok Pesantren Al Marhabaniyyah Amelia Sabila; Ulfa Nurullita; Nur Khamilatusy Sholekhah; Risyandi Anwar
MAHESA : Malahayati Health Student Journal Vol 6, No 5 (2026): Volume 6 Nomor 5 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i5.22261

Abstract

ABSTRACT Oral health contributes significantly to general body health. The purpose of this study was to assess the relationship between oral hygiene knowledge and tooth brushing behavior  with oral hygiene status among students of Pondok Pesantren Al Marhabaniyyah. The research design was observational with a cross-sectional approach. The population consisted of 82 students, selected using a total sampling technique. Data were collected through a knowledge questionnaire, observation of tooth brushing behavior, and oral hygiene examination using the Simplified Oral Hygiene Index (OHI-S). Data analysis was conducted using the Spearman Rank test. The results showed a significant relationship between knowledge of oral hygiene and oral hygiene status (p = 0.032; r = -0.237), indicating that higher knowledge was associated with better oral hygiene status. However, no significant relationship was found between tooth brushing behavior and oral hygiene status (p = 0.481; r = -0.079). In conclusion, knowledge plays an important role in influencing oral hygiene, whereas tooth brushing behavior did not show a significant correlation. Keywords: Knowledge, Tooth Brushing Behavior, OHI-S, Oral Hygiene.  ABSTRAK Kesehatan gigi dan mulut memiliki fungsi utama dalam menjaga kesehatan tubuh secara menyeluruh. Penelitian ini memiliki tujuan untuk mengetahui hubungan pengetahuan tentang kebersihan rongga mulut dan perilaku menggosok gigi dengan status kebersihan rongga mulut pada santri Pondok Pesantren Al Marhabaniyyah. Penelitian ini dirancang menggunakan metode observasional dengan desain cross-sectional. Populasi dalam penelitian ini mencakup seluruh santri berjumlah 82 responden dengan teknik total sampling. Data dikumpulkan melalui kuesioner pengetahuan, observasi perilaku menggosok gigi, serta pemeriksaan status kebersihan rongga mulut menggunakan Oral Hygiene Index-Simplified (OHI-S). Analisis data menggunakan uji Rank Spearman. Hasil penelitian menunjukkan adanya hubungan yang signifikan antara pengetahuan tentang kebersihan rongga mulut dengan status kebersihan rongga mulut (p = 0,032; r = -0,237). Hal ini mengindikasikan semakin tinggi pengetahuan, maka semakin baik status kebersihan rongga mulut. Namun, tidak terdapat hubungan yang signifikan antara perilaku menggosok gigi dengan status kebersihan rongga mulut (p = 0,481; r = -0,079). Kesimpulannya, pengetahuan berperan penting dalam memengaruhi kebersihan rongga mulut, sedangkan perilaku menggosok gigi belum menunjukkan hubungan yang berarti. Kata Kunci: Pengetahuan, Perilaku menggosok Gigi, OHI-S, Kebersihan Rongga Mulut.
Deteksi Dini Karies Gigi sebagai Upaya Pencegahan Penyakit Gigi dan Mulut pada Siswa Diaspora di Sekolah Indonesia Jeddah dan Mekkah, Arab Saudi Hayyu Failasufa; Nur Khamilatusy Sholekhah; Megawati Prajarini; Risyandi Anwar; Ika Rachmawati; Gelar Subhakti Ramdhani; Putri Dhianita Pratiwi; Muhammad Destyatosa Irfani
Jurnal Pengabdian UNDIKMA Vol. 7 No. 2 (2026): May
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v7i2.19482

Abstract

This community service activity aims to conduct early detection of oral health problems through simple preliminary examinations using clinical instruments, while improving students’ knowledge through oral health education as an effort to prevent dental and oral diseases. The program involved 110 students from the Indonesian Schools in Jeddah and Mecca. The activity was implemented using a health empowerment approach, with dental and oral examinations conducted using the Oral Health Surveys: Basic Methods issued by the World Health Organization (WHO). The collected data were analyzed based on frequencies and percentages. The screening results showed a high prevalence of dental caries, with 51.8% of students having a DMF-T score > 0. The 10–12-year age group accounted for the highest proportion of caries cases at 73.6%. The most commonly required treatment recommendation was dental fillings, representing 38.2% of cases. The high prevalence of caries among diaspora students highlights the importance of sustainable early detection programs and oral health education. This intervention is expected to foster good oral hygiene habits from an early age in order to prevent more severe dental diseases in the future.
Co-Authors Ace Tatang Hidayat Al Arofatus Naini Al Arofatus Naini Amelia Sabila Anisdyasarathi, Fitri Anjari, Intan Hawina Aprillia, Zita Arlette Setiawan Arlette Setiawan Arlette Setiawan Arlette Setiawan Arlette Suzy Puspa Pertiwi Darwati Darwati Delia Ilfani Desi Harneti Desi Harneti Putri Huspa Deviana Adinda Nurfatimah Dewi, Anisa Candra Dzanuar Rahmawan Erina Hilmayanti Etny Dyah Harniati Failasufa, Hayyu Faizah Maira Farabi, Kindi Faridia Puspita Lestari Gabrilia Dwi Agustina Gelar Subhakti Ramdhani Hadi Kuncoro I Kadek Sudartayasa Ika Rachmawati Intan Hawina Anjari Khalijah Awang Kindi Farabi Kindi Farabi Lilis Siti Aisyah Lisa Oktaviana Mayasari Mastura, Nurul Izzah Maya Dian Rakhmawatie Mayasari, Lisa Oktaviana Megawati Prajarini Mohamad Nurul Azmi Muhamad Nurul Azmi Muhammad Destyatosa Irfani Naini, Al Arofatus Nikmaturrizqi, Nada Nisma Dinastiti Nisma Dinastiti Niswatun Chasanah Nurhidayah, Rizky Nurlelasari Nurlelasari Pebrian Diki Prestya Puspito Ratih Hardhani Putri Dhianita Pratiwi Putri, Ghesta Alifka Rani Maharani Rani Maharani Ratna Sulistyorini, Ratna Rizky Nurhidayah Samuel San Parulian Sarni Sawitri Dwi Indah Pertami Sayono Sholekhah, Nur Khamilatusy Sinaga, Siska Elisahbet Sofa Fajriah Steffi Triany Arnov Suaeni Kurnia Wirda Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Supriatno Sutiyono, Triagus Nursasongko Syarifah Nova Amiza Zam Tri Mayanti Tri Mayanti Tripermata, Anita Novia Tyas Nurfadlilah Amaliah Ulfa Nurullita Unang Supratman Vidia Afina Nuraini Yenny Febriani Yun Yoshihito Shiono