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All Journal Medula JKM (Jurnal Kebidanan Malahayati) Jurnal Ilmu Kedokteran dan Kesehatan Respiratory Science JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Saputra, Tetra Arya
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : Medula

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Rapid Diagnosis and Management of Concomitant Acute Cardiogenic Pulmonary Edema and Community-Acquired Pneumonia Increase Patient Survival Wibowo, Adityo; Saputra, Tetra Arya
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.961

Abstract

Acute pulmonary edema is a potentially life-threatening complication of cardiac disease that leads to acute respiratory failure. Cardiogenic pulmonary edema affects approximately 80% of patients with acute decompensated heart failure. Acute pulmonary edema caused by heart failure affects nearly a million individuals annually, and the number of cases is growing significantly as the ejection fraction reduces. The clinical presentation can be identified by a sudden onset of dyspnea and a quick accumulation of fluid inside the alveolar and lung interstitial secondary to an increase in hydrostatic pressure. Community-acquired pneumonia (CAP) is the most common respiratory infection caused by a microbial infection of the lung parenchyma and has almost similar clinical characteristics to acute pulmonary edema. The length of stay in hospital will increase nearly two times longer in these concomitant diseases. Comorbidity of cardiogenic lung edema and CAP increase mortality rate by nearly 25% in heart failure patients without early detection and proper management.
Proper Management of Underweight and Anemia in Tuberculosis Patients Increases The Improvement Time During Two-Week Treatment Follow-Up Saputra, Tetra Arya; Wibowo, Adityo
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.991

Abstract

Tuberculosis (TB) continues to be the leading cause of disease and mortality caused by chronic pulmonary infection. The World Health Organization (WHO) considers that one-third of the global population is infected with Mycobacterium tuberculosis (Mtb).  Mycobacterium tuberculosis infection results in persistent lung damage, which is characterized by ongoing inflammation that damages lung tissue. The patient additionally experienced a cough for almost one month, with clear mucous, absence of blood, and mild shortness of breath. Patients had decreases in body weight and loss of appetite for about three weeks. Night sweats appeared within one month. There was no specific complaint of gastrointestinal symptoms. The patient's nutritional management was focused primarily on oral intake, with a total daily consumption of 1690 kcal. The daily protein, carbohydrate, and fat consumption is divided into 42.45 grams of protein, 253.5 grams of carbohydrates, and 37.5 grams of fat. There was no history of food allergy from the patient, therefore we decided not to impose any dietary restrictions. The improvement in body weight was used to monitor the outcome of the nutritional intervention. Nutritional issues have emerged as a significant contributor to an increasing percentage of individuals with low hemoglobin (Hb), influencing TB-related morbidity. The most prevalent causes of anemia in tuberculosis are nutritional deficiencies and malabsorption as a result of appetite loss. Poor intake of food has also been linked to an increased risk of disseminated TB. To improve treatment outcomes, nutritional support should be provided in addition to tuberculosis medicine.
Pneumonia as a Secondary Complication Related to Inhaled Corticosteroid Combination Treatment for Chronic Obstructive Pulmonary Disease with Eosinophilic Phenotype Patient Wibowo, Adityo; Saputra, Tetra Arya
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1199

Abstract

Chronic obstructive pulmonary disorder (COPD) is a progressive respiratory condition characterized by chronic inflammation, proteases and antiproteases imbalance, and airway remodeling. Several hypotheses, including immune dysregulation, microbial colonization, and environmental triggers, explain the underlying cause of the deteriorating state and recurrence of exacerbations in COPD. Eosinophils, one of the inflammatory mediators, are involved in about 30% of cases of COPD. In COPD with an eosinophilic phenotype, specific therapy recommendations include inhaled corticosteroids (ICS) combined with a long-acting bronchodilator therapy typically includes the combination of inhaled corticosteroids (ICS) (e.g., fluticasone, budesonide) and a long-acting bronchodilator (LABA) (e.g., formoterol, salmeterol) to improve airflow and reduce inflammation. While ICS therapy is beneficial, side effects of pulmonary infections become more likely as the dose increases, particularly with prolonged use. The risk of pneumonia can be managed through dose optimization and careful patient monitoring.
Co-Authors Adityo Wibowo, Adityo Apri Lyanda Azka, Laisa Choerunnisa, Nida Ekawati, Diyan Elisna Syahruddin Erlina Burhan Erumbia, Ilham Akbar Fitriyah Fitriyah Gatot Sudiro Hendarto, Gatot Sudiro Ginting, Bisart Benedicto Herdato, M. Junus Didiek Infianto, Andreas Listiandoko, Raden Dicky Wirawan M., Tria Morfi, Chicy Widia Morfi, Chicy Widya Pratama, Arianda Putranata, Naufal R. Putranta, Naufal Rafif Rizki Putra Sanjaya Rusmini, Hetti Sinaga, Fransisca T Y Soemarwoto, Retno Ariza Soemarwoto, Retno Ariza S. Soeprihatini, Retno Ariza S. Sukarti Sukarti Syazili Mustofa