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Uji Aktivitas Face Mist Ekstrak Etanol Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) sebagai Antibakteri terhadap Staphylococcus aureus, Staphylococcus epidermis, Propionibacterium acnes Hayati, Noor; Chandra, M. Andi; Fitriyanti
MPI (Media Pharmaceutica Indonesiana) Vol. 6 No. 1 (2024): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v6i1.6342

Abstract

Ekstrak umbi Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) memiliki aktivitas antibakteri pada S. aureus, S. epidermidis serta P. acnes dan dapat dikembangkan dalam bentuk sediaan yang kemudian dapat diuji aktivitas antibakterinya. Tujuan penelitian ini yaitu mengetahui aktivitas antibakteri dari variasi konsentrasi zat aktif pada formula face mist ekstrak etanol 96% bawang dayak (Eleutherine bulbosa (Mill.) Urb.). Metode pengujian aktivitas antibakteri dilakukan menggunakan metode difusi agar. Adapun variasi konsentrasi ekstrak 2%, 4%, 6% dan 8%. Hasil penelitian ini menunjukkan bahwa aktivitas antibakteri Face mist ekstrak etanol 96% bawang dayak (Eleutherine bulbosa (Mill.) Urb.) terhadap bakteri S. aureus konsentrasi 8% (6,51 mm) tergolong kategori sedang. Pada bakteri S. epidermidis (12,33 mm) aktivitasnya termasuk kategori kuat. Sementara pada bakteri P. acnes (7,15 mm) kategori sedang. Kesimpulannya pada F4 face mist menghasilkan zona hambat lebih tinggi dibandingkan F1(2%), F2(4%) dan F3 (6%) terhadap bakteri S. aureus, S. epidermidis dan P. acnes. Pada analisis data diuji dengan Mann Whitney, didapatkan hasil pada formula F1, F2, F3 dan F4 memiliki nilai signifikansi p≤0,05 terhadap kontrol positif yang berarti terdapat perbedaan antar keempat formula dengan kontrol positif. Dayak Onion Bulb extract (Eleutherine bulbosa (Mill.) Urb.) has antibacterial activity on S. aureus, S. epidermidis and P. acnes, can be developed as a dosage form, and further tested as antibacterial agent. The aim of this research was determine the antibacterial activity of variations in the concentration of active substances in the face mist formula containing 96% ethanol extract of Dayak onion (Eleutherine bulbosa (Mill.) Urb.). The antibacterial activity testing method was carried out using the disc method with varying extract concentrations of 2%, 4%, 6% and 8%. The results of this study showed that the antibacterial activity of face mist 96% ethanol extract of Dayak onion (Eleutherine bulbosa (Mill.) Urb.) against S. aureus bacteria was at a concentration of 8% (6.51 mm) in medium category. In S. epidermidis bacteria (12.33 mm) was strong category. In P. acnes bacteria (7.15 mm) was medium category. In conclusion, F4 face mist produced a higher zone of inhibition than F1 (2%), F2 (4%) and F3 (6%) against S. aureus, S. epidermidis and P. acnes bacteria. In data analysis tested with Mann Whitney, the results obtained for F1, F2, F3 and F4 had a significance value of p≤0,05 against the positive control, which means there was a difference between the four formulas and the positive control.
Level of Knowledge and Use of Traditional Medicine in Outpatients of Mekarsari Health Center, Barito Kuala Regency Rakhmatullah, Aditya Noviadi; Yunarti, Azmi; Chandra, M. Andi; Muliyati, Imas
Jurnal Publikasi Kesehatan Masyarakat Indonesia Vol 11, No 3 (2024): Jurnal Publikasi Kesehatan Masyarakat Indonesia
Publisher : Lambung Mangkurat University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpkmi.v11i3.20921

Abstract

The use of herbal medicine as a treatment is increasing, especially in Mekarsari District, Barito Kuala Regency. Without proper education, traditional medicine practices can have a negative impact on health. The purpose of this study was to determine the level of knowledge and use of traditional medicine in patients seeking treatment at the Mekarsari Health Centre. This study used a descriptive method with a quantitative approach. The population in this study were all outpatients at the Mekarsari Health Centre in January 2023. This study used a purposive sampling technique in sampling and used a validated questionnaire instrument in data collection. The results showed that 47% of respondents had a sufficient level of knowledge, 25% had a good level of knowledge, 14% had a poor level of knowledge, and 13% had a poor level of knowledge. Based on the method of obtaining traditional medicine, it is known that 55% said that it was from herbal medicine sellers in the form of powder or infusions with a duration of use ranging from one to three days. The majority of traditional medicine users use it to relieve pain and aches (22%). Based on the effects after consuming traditional medicine, 78% said they felt better and 99% said they had no side effects.
Analysis of the Relationship between Knowledge Level and the Use of Traditional Medicine in Sungai Rutas Village Rusida, Esty Restiana; Chandra, M. Andi; Maulida, Siti Rahmah; Akbar, Depy Oktapian; Rakhmatullah, Aditya Noviadi
Jurnal Publikasi Kesehatan Masyarakat Indonesia Vol 11, No 3 (2024): Jurnal Publikasi Kesehatan Masyarakat Indonesia
Publisher : Lambung Mangkurat University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpkmi.v11i3.20918

Abstract

Traditional medicines are widely used by people from the herbal medicine group, standardized herbal medicines and phytopharmaca. People know that traditional medicine is limited to herbal medicine and standardized herbal medicine. while phytopharmaca still sounds unfamiliar to the public. Regarding knowledge and use of medicines that are beneficial for health in traditional medicine, it is still limited, the majority of people consume traditional herbal medicines as many as 100 people, which they make themselves using nutritious plants. The aim of the research was to determine the relationship between knowledge and the use of traditional medicine in Sungai Rutas Village. Analytical observation research method with a cross sectional approach. The sampling technique uses non-probability sampling containing 100 samples. The results of the research show that the level of knowledge of the majority of people is sufficient, as many as 54 people (54%), and the majority of people's use of traditional medicine is sufficient, as many as 45 people (45%). Apart from that, the results of relevant statistical analysis, namely the chi-square test, found that there was a relationship between knowledge (p-value = 0.008) and the use of traditional medicine as alternative medicine in the community in Sungai Rutas Village, Tapin Regency. The conclusion was that the level of public knowledge regarding the use of traditional medicine was sufficient knowledge, namely 54 people (54%). 46 people (46%) used traditional medicine. The conclusion in this study is that there is a relationship between the level of knowledge and compliance with a p-value = 0.008.
Pengaruh Pemberian Minyak Biji Kelor (Moringa seeds oil) Terhadap Kadar Trigliserida Pada Darah Tikus Putih Jantan Galur Wistar (Rattus norvegicus) Amalia, Nurul; Norhayati; Chandra, M. Andi; Rusida, Esty Restiana
Acta Pharmaceutica Indonesia Vol. 49 No. 2 (2024)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT Elevated triglyceride levels can be managed through non-pharmacological approaches, including the use of moringa seeds. These seeds are rich in fatty acids that exhibit potential in reducing hyperlipidemia. This research is designed to assess the impact of moringa seed oil on triglyceride concentrations in male Wistar strain white rats (Rattus norvegicus) administered with different doses. Utilizing a Posttest-Only Control Group Design, the experiment was conducted across five groups: K1 (positive control), K2 (negative control), K3 (3 mL moringa seed oil), K4 (6 mL moringa seed oil), and K5 (9 mL moringa seed oil). Measurements were taken after treatment. Statistical analysis revealed a significant difference in triglyceride levels between the negative control group and the groups treated with moringa seed oil (p = 0.018, p < 0.05), indicating the oil's effectiveness in reducing triglyceride levels. Furthermore, Post-Hoc LSD analysis showed a significant difference between K4 and K5, with p = 0.045 (p < 0.050). These findings suggest that moringa seed oil significantly reduces triglyceride levels, particularly at higher doses. This research determided the therapeutic potential of moringa seed oil in managing hyperlipidemia by lowering blood triglyceride levels in male Wistar rats (Rattus norvegicus).
Empowerment of Women Farmers’ Groups in the Production of Instant Ginger with Butterfly Pea Flower Combination and Business Legality Education Chandra, M. Andi; Yunarti, Azmi; Khairunnisa, Khairunnisa; Putri, Aristha Novyra
DIKDIMAS : Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2025): DIKDIMAS : JURNAL PENGABDIAN KEPADA MASYARAKAT  VOL 4 NO 1 APRIL 2025
Publisher : Asosiasi Profesi Multimedia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/dikdimas.v4i1.384

Abstract

This Community Service Program (PkM) was designed to empower the Cemara Women Farmers Group (KWT) by combining the development of practical skills with the enhancement of business acumen. The core focus of the program was to provide comprehensive training in the production of instant ginger powder, enriched with the beneficial properties of butterfly pea flower, and to deliver essential education on business legality. To achieve these objectives, the program followed a structured methodology that included initial surveys to thoroughly assess the needs and existing knowledge of the participants, careful coordination of activities, informative counseling sessions, hands-on training and mentoring to cultivate effective production techniques, targeted education on business legality to foster sustainable business practices, and a rigorous evaluation process to accurately measure the program's overall impact. The results of the PkM demonstrated a marked improvement in the knowledge levels of the participants, evidenced by a statistically significant increase in average scores from the pre-test (80.34%) to the post-test (92.47%), alongside a notable rise in enthusiasm and active engagement among the KWT Cemara women. In conclusion, the program effectively empowered the KWT Cemara members by providing them with the necessary skills and knowledge to enhance their production capabilities and establish sustainable business operations.
Pengaruh Variasi Konsentrasi Sukrosa pada Formulasi Gummy Candies Sari Buah Belimbing Wuluh Kombinasi Lemon sebagai Produk Nutraceutical Chandra, Muhammad Andi; Alfina, Sophia; Dewi, Citra Kharisma; Pinanggi, Alfasyah Oktarini Pinanggi; Nur Mulia, Shilfa Nadira; Nurlifa, Mya; Chandra, M. Andi
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.539

Abstract

Lemon and starfruit are fruit plants used in traditional medicineThe purpose of this study was to determine how differences in sugar content affected the way gummy candy was made. This study's methodology included the creation of five different gummy sweets using starfruit juice and lemon. Physical quality assessments, such as organoleptic testing, pH, weight uniformity, elasticity tests, water content tests, and hedonic tests, were also conducted. The study's findings demonstrated that the gummy sweets' flavor became sweeter with increasing sugar content. As can be seen, formula 5 has the maximum sucrose content at 1.5 grams. The conclusion reached is that changes in the amount of sucrose used as a sweetener may affect the preparation's physical quality evaluation test results as well as the respondent's hedonic test evaluation. It was discovered that formula 2 and 4, which included 0.5 grams and 0,2 grams of sucrose, was the one that responders liked the best.
FORMULASI SEDIAAN GUMMY CANDIES INFUSA BUAH KARAMUNTING (Rhodomyrtus tomentosa (AITON) HASSK.) Rakhmatullah, Aditya Noviadi; Chandra, M. Andi
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.615

Abstract

Karamunting plant (R. tomentosa) (Aiton) Hassk.) is a plant that can be used as a source of natural antioxidants. Karamunting contains active compounds of natural antioxidants such as flavonoids. The purpose of this study was to find out the best formula based on the physical characteristics of the karamunting fruit infusion gummy candies preparation with different gelatin content and to determine the level of respondent's preference for the karamunting fruit infusion gummy candies preparation. The gummy candies formulation was made with variations in gelatin concentration of 7%, 9%, 10%, and 11%. The physical evaluations carried out included organoleptic tests, pH tests, water content tests, weight uniformity tests, elasticity tests, and hedonic tests. The organoleptic results showed that F1 and F2 were green in color, tasted not sweet, had a melon aroma, were semi-solid, and had a texture that was easily crushed or not chewy. F3 and F4 are green in color, taste less sweet and sweet, melon aroma, semi-solid, chewy texture, evaluation of gummy candies preparations shows pH 5.01-6.38, but the water content exceeds the requirements, namely 92.59% -58.11%. Based on the results of the study, it was concluded that based on the physical characteristics of the gummy candies infusion preparation of karamunting fruit, formula III met the requirements based on the results of the physical test of the preparation and became the most preferred formula based on the hedonic test
FORMULASI GUMMY CANDIES BELIMBING WULUH KOMBINASI LEMON DENGAN VARIASI KONSENTRASI DAUN CINCAU HIJAU Chandra, M. Andi; Noviadi Rakhmatullah , Aditya; Fauzana, Erwin
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 25 No 2 (2025): Jurnal Kesehatan Bakti Tunas Husada Volume 25 Nomor 2 Tahun 2025
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v25i2.1686

Abstract

ABSTRAK Nutraseutikal adalah produk suplemen makanan atau herbal yang dapat memberikan manfaat bagi kesehatan dalam pencegahan dan pengobatan penyakit yang berasal dari bahan-bahan alami. Gummy candies yaitu suatu sediaan produk manisan yang berbentuk lunak seperti jelly. Tekstur permen jelly dipengaruhi oleh bahan pembentuk gel atau hidrokoloid yang digunakan Salah satu tanaman yang mengandung antioksidan tinggi adalah belimbing wuluh. Belimbing wuluh digunakan sebagai zat aktif dalam sediaan gummy candies. Penelitian ini memiliki tujuan untuk mengetahui karakteristik gummy candies berdasarkan gelling agent alami yang digunakan dari sari daun cincau hijau (Cyclea barbata Miers.). Sediaan gummy candies dibuat dengan variasi konsentrasi yaitu 10% (F1), 20% (F2), 30% (F3), dan 40% (F4). Sediaan gummy candies dilakukan uji evaluasi meliputi organoleptis, pH, kadar air, keseragaman bobot, elastisitas, dan uji hedonik berdasarkan bentuk, warna, rasa, dan tekstur. Evaluasi hasil uji organoleptis berwarna merah, memiliki rasa pisang ambon, aroma khas, dan tekstur sangat kenyal. Uji pH (5,13-5,20), Uji kadar air (66%-72%), Uji keseragaman bobot kurang (1,093-1,269), Uji elastisitas (1,06-1,76). Berdasarkan hasil uji hedonik diketahui bahwa formulasi 3 dengan kadar sari daun cincau hijau sebanyak 30% adalah formulasi paling optimal karena lebih disukai oleh responden dan diterima dengan baik, dari sisi bentuk, warna, rasa, dan tekstur. Formulasi terbaik pada penelitian ini yaitu formula 3. Kata Kunci : Belimbing wuluh, Gummy candies, Cincau hijau, Pektin, Gelatin.
Daya Hambat Formula Optimum Sabun Cair Daun Bandotan (Ageratun conyzoides) terhadap Bakteri Staphylococcus aureus dan Pseudomonas aeruginosa Chandra, M. Andi; Afra, Fairuz Yaumil; Rahmiati, Nur
Bioscientist : Jurnal Ilmiah Biologi Vol. 12 No. 2 (2024): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i2.12914

Abstract

Infeksi bakteri lebih sering terjadi pada kulit karena kulit merupakan lapisan terluar tubuh. Ada bukti bahwa daun tanaman bandotan memiliki sifat antibakteri. Pengembangan formulasi sabun cair memungkinkan daun bandotan untuk mencapai potensi penuhnya. Penelitian ini bertujuan untuk mengetahui seberapa efektif sabun cair terhadap mikroorganisme Staphylococcus aureus dan Pseudomonas aeruginosa. Studi ini merupakan penelitian ekspirimen yang dilakukan di laboratorium untuk menguji aktivitas antibakteri sabun daun bandotan menggunakan difusi sumur pada bakteri Staphylococcus aureus dan Pseudomonas aeruginosa. Hasil penelitian menunjukkan bahwa bakteri Pseudomonas aeruginosa memiliki zona hambat sebesar 2 mm, yang termasuk kategori lemah, sedangkan bakteri Staphylococcus aureus memiliki zona hambat rata-rata sebesar 13 mm, yang termasuk kategori kuat. Dengan demikian, sediaan sabun cair memiliki nilai zona hambat rata-rata yang termasuk dalam kategori kuat terhadap bakteri Staphylococcus aureus. Nilai zona hambat rata-rata ketika diujikan terhadap bakteri Pseudomonas aeruginosa masuk ke dalam kategori aktivitas antibakteri yang kurang baik
Pemberdayaan Kelompok Wanita Tani dalam Pembuatan Teh Daun Bangkal (Nauclea Orientalis) Lokal Kalimantan Chandra, M. Andi; Marliadi, Reny; Nurbidayah, Nurbidayah; Kartinah, Nani; Mulia, Shilfa Nadira Nur; Hanifa, Amanda
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 7, No 10 (2024): Volume 7 No 10 (2024)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v7i10.17313

Abstract

ABSTRAK Kelompok Wanita Tani (KWT) Mekar Pejaratan terletak dikecamatan Astambul. Kabupaten Banjar. Petani merupakan bagian terbesar dari penduduk setempat. Kegiatan pertanian, termasuk menanam daun bangkal, dimungkinkan oleh potensi alam daerah tersebut. Tujuan kegiatan ini memberikan edukasi manfaat daun bangkal dijadikan produk, pembuatan simplisia dan pembuatan kemasan dan labelling. Metode yang digunakan yaitu perencanaan, pelaksanaan dan evaluasi. Hasil kegiatan ini menunjukkan bahwa seluruh anggota tim mitra sepakat dengan pelaksanaan proyek pengabdian kepada masyarakat dan mengantisipasi bahwa proyek ini akan terus berlanjut. Berdasarkan hasil penilaian program pelatihan pembuatan produk, sosialisasi ulang indikator peralatan produksi diperlukan untuk memastikan kelancaran operasional seluruh proses produksi. Kata Kunci: Pemberdayaan, Daun Bangkal, Kelompak Wanita Tani, Teh  ABSTRACT The sub-district of Astambul is home to the Mekar Pejaratan Women Farmers Group (KWT). Regency of Banjar. Farming is the main occupation of most locals. Agricultural pursuits, including growing bangkal leaf plants, are made possible by the area's natural potential. Participation in this event will help spread the word about the many uses for bangkal leaves, making simplicia and making packaging and labeling. The methods used are planning, implementation and evaluation. The conclusion of this activity was that overall the entire partner team strongly agreed and agreed with the implementation of community service activities and hoped for sustainable activities. In the evaluation of product manufacturing training activities, it was found that production equipment indicators needed to be re-socialized regarding the use of production equipment so that production aspects could run well and smoothly. Keywords: Empowerment, Bangkal Leaves, Women Farmers Group, Tea