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All Journal Jurnal Imejing Diagnostik Journal of Health (JoH) Molecular and Cellular Biomedical Sciences (MCBS) Oceana Biomedicina Journal Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Jurnal Pengabdian Masyarakat (ABDIRA) Indonesian Journal of Life Sciences Journal of Tropical Biodiversity Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan SEGARA : Jurnal Pengabdian Kepada Masyarakat Multidisciplinary Indonesian Center Journal Poltekita: Jurnal Pengabdian Masyarakat Altius: Jurnal Ilmu Olahraga dan Kesehatan
Bunga Anggreini Sari
Universitas Pembangunan Nasional Veteran Jakarta
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Effectiveness of Mesenchymal Stem Cells and Their Derivatives in Modulating Oxidative Stress in Neurodegenerative Diseases: A Structured Narrative Review Niken Rahmah Ghanny; Putu Erma Pradnyani; Assyafiya Salwa; Herera Rahajeng; Afifa Radhina; Bunga Anggreini Sari; Ichwan Baihaki
Indonesian Journal of Life Sciences 2026: IJLS Vol 08 No.01
Publisher : Universitas Bio Scientia Internasional Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54250/ijls.v8i01.297

Abstract

Background: Oxidative stress plays a critical role in the development and progression of neurodegenerative diseases such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and amyotrophic lateral sclerosis (ALS). Mesenchymal stem cells (MSCs) and their derivatives have emerged as promising therapeutic strategies due to their antioxidant, anti-inflammatory, and neuroprotective properties. Objective: This review evaluated the effectiveness of MSC-based interventions in modulating oxidative stress in neurodegenerative disease models. Methods: A structured narrative review search was conducted following PRISMA 2020 guidelines using PubMed and Scopus databases for studies published between 2020 and 2025, with the last search in December 2025. Results: 33 studies met the inclusion criteria, primarily involving Parkinson’s and Alzheimer’s disease models. Overall, MSC-based therapies reduced oxidative stress markers, enhanced antioxidant defenses, activated the Nrf2/HO-1 pathway, improved mitochondrial function, and reduced neuroinflammation in experimental neurodegenerative disease models.
Beyond BMI in Community Health Promotion: An Integrated Anthropometric, Physiological, and Functional Screening Approach among Urban Women in East Jakarta, Indonesia Ichwan Baihaki; Taufiq Fredrik Pasiak; Afifa Radhina; Assyafiya Salwa; Bunga Anggreini Sari; Fransiskus Samuel Renaldi; Herera Rahajeng; Muhammad Fadhil; Niken Rahmah Ghanny; Ria Apriliani
Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan (Abdigermas) Vol. 4 No. 2 (2026): Jurnal Ilmiah Pengabdian Kepada Masyarakat Bidang Kesehatan (Abdigermas)
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/abdigermas.v4i2.750

Abstract

Background: Community-based preventive screening is important for reducing non-communicable disease risk among adult women, particularly those who influence household health practices. However, screening activities frequently emphasize Body Mass Index (BMI), although BMI alone may not adequately describe central adiposity, elevated blood pressure, and functional health indicators. This community service article aimed to describe the implementation of health education and integrated screening involving anthropometric, physiological, and functional measurements among female guardians at Yayasan Tarbiyatul Yatim, East Jakarta, Indonesia.Aims: This study aimed to (1) implement a community-based health education and screening program for adult female participants, (2) assess anthropometric, physiological, and functional health indicators including blood pressure, BMI, waist circumference, and hand grip strength, and (3) identify the prevalence of potential cardiometabolic and functional risk markers beyond BMI.Methods: This activity was implemented on January 8, 2026 using a preventive-promotive community service framework with descriptive program evaluation. Thirty-two adult female participants joined health education, screening, and individual consultation. The community service dataset included blood pressure, pulse, oxygen saturation, body temperature, body weight, height, BMI, waist circumference, hand grip strength, health history, lifestyle profile, and current complaints. Data were analyzed descriptively using frequency, percentage, mean, median, standard deviation, and range.Result: The participants had a mean age of 49.8 years. Mean systolic and diastolic blood pressure were 129.2 mmHg and 78.8 mmHg, respectively. Mean BMI was 24.9 kg/m²; 16/32 participants (50.0%) were categorized as normal, 9/32 (28.1%) overweight, 4/32 (12.5%) obese, and 3/32 (9.4%) underweight. Mean waist circumference was 97.7 cm, and 29/32 participants (90.6%) had waist circumference >80 cm. Mean hand grip strength was 16.5 kg, and 21/32 participants (65.6%) had values <18 kg.Conclusion: Integrated screening beyond BMI is feasible in community service settings and can help identify potential cardiometabolic and functional risk indicators that require counseling or referral. Future activities should include documented repeat measurements for abnormal findings, structured pretest-posttest educational evaluation, biochemical testing, and referral follow-up.
Peningkatan Pengetahuan Kanker Serviks Pada Komunitas Lokal Melalui Edukasi Berbasis Pre-test dan Post-test Bunga Anggreini Sari
Segara : Jurnal Pengabdian Kepada Masyarakat Vol 3 No 2 (2025): Vol. 3 No. 2 (2025): SEGARA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Kedokteran UPN "Veteran" Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/segara.v3i2.12361

Abstract

Kanker serviks merupakan salah satu penyebab utama morbiditas dan mortalitas pada wanita di dunia, termasuk di Indonesia. Rendahnya tingkat pengetahuan masyarakat menjadi hambatan utama dalam upaya pencegahan dan deteksi dini kanker serviks. Tujuan pengabdian masyarakat ini adalah meningkatkan pengetahuan masyarakat tentang kanker serviks melalui edukasi berbasis pre-test dan post-test. Metode yang digunakan adalah ceramah dan diskusi dengan sasaran Komunitas Arisan "Manjah Squads" yang berjumlah 10 orang pada tanggal 26 Agustus 2025. Evaluasi dilakukan menggunakan kuesioner pre-test dan post-test dengan 10 pertanyaan, kemudian dianalisis menggunakan paired t-test. Hasil menunjukkan peningkatan signifikan tingkat pengetahuan peserta dari rata-rata skor pre-test 6,5 menjadi 9,3 pada post-test (p<0,001). Mayoritas peserta berusia 40-49 tahun (70%), berpendidikan S1 (70%), dan berprofesi sebagai ibu rumah tangga (70%). Program edukasi berbasis komunitas terbukti efektif dalam meningkatkan pengetahuan tentang kanker serviks dan dapat direplikasi di komunitas serupa untuk mendukung upaya pencegahan kanker serviks di tingkat masyarakat.
Energy System Contributions to Sports Performance: A Systematic Review Afifa Radhina; Niken Rahmah Ghanny; Herera Rahajeng; Assyafiya Salwa; Ichwan Baihaki; Bunga Anggreini Sari; Fransiskus Samuel Renaldi
Altius: Jurnal Ilmu Olahraga dan Kesehatan Vol. 15 No. 1 (2026): Altius: Jurnal Ilmu Olahraga dan Kesehatan
Publisher : Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/altius.v15i1.203

Abstract

Understanding how the body produces and utilizes energy during exercise is key to enhancing athletic performance and refining training strategies. This systematic review analyzes recent studies on the contributions of the phosphagen (ATP-PCr), glycolytic (anaerobic), and oxidative (aerobic) energy systems in various sports. The review follows PRISMA 2020 guidelines and includes studies published between 2020 and 2025, selected from Scopus, PubMed, Google Scholar, and Web of Science. Energy system contributions were evaluated using markers such as oxygen uptake, substrate utilization, blood lactate levels, and ATP turnover rates. The review finds that in high-intensity, short-duration events like the 100m sprint, the phosphagen system accounts for 70%, while glycolytic and oxidative systems contribute 25% and 5%, respectively. In endurance events such as marathons, oxidative metabolism dominates, contributing 85–95% of total energy. Sports with mixed intensity, such as soccer and basketball, show dynamic contributions, with oxidative metabolism at 50–60%, phosphagen at 20–30%, and glycolytic at 15–25%. These results highlight the importance of sport-specific training to optimize energy system interactions and performance.
Co-Authors Afifa Radhina Andi Zsazsa Rafiatul Mukhlis Anisah Assyafiya Salwa Assyafiya Salwa Assyafiya Salwa Azalia Talitha Zahra Baehaqi Devina Liya de’Ornay, Amelia Rina Nogo Diana Sartika Dinda Rahma Dita Rahmalia Eddy Mart Salim Effendi, Alvira Noer Effendi, Kms. Yusuf Erma Pradnyani, Putu Fadhillah, Hilwa Syifa Ganda Purba Tasti Handayani , Sri Harry Wahyudhy Utama Ichwan Baihaki Irsan Saleh Juniarti, Ariska Khairunisah, Siti Delvia Kurnianingsih, Susi Legiran Legiran Lilis Rosalina Marlina, Devi Muhammad Fadhil Muhammad Fadhil Muliani, Rizka MUSLIMAH PUTRI UTAMI Muslimin Muslimin MUSTIKA FATIMAH Niken Rahmah Ghanny Niken Rahmah Ghanny Niken Rahmah Ghanny Nova Mabela Rahajeng, Herera Rapi Dzaki Almugni Razi, Fakhri Renaldi, Fransiskus Samuel Ria Apriliani Rosalina, Lilis Sukrisno, Adi Taufiq Fredrik Pasiak Tety Septiani Wardiansah, Wardiansah Wika Sepiwiryanti Ziske Maritska