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All Journal Biogenesis: Jurnal Ilmiah Biologi Jurnal Biologi Tropis Jurnal Biolokus: Jurnal Penelitian Pendidikan Biologi dan Biologi JPBIO (Jurnal Pendidikan Biologi) Jurnal AbdiMas Nusa Mandiri Journal of Natural Sciences Sriwijaya Bioscientia Jurnal Pengabdian Masyarakat Aufa (JPMA) BIOVALENTIA: Biological Research Journal Jurnal Sylva Lestari Jurnal Medika: Medika Biodiversitas Journal of Biological Diversity
Yadi Oktariansyah
Department Of Biology, Faculty Of Mathematics And Natural Sciences, Sriwijaya University
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Analisis In Silico Metabolit Sekunder Lansium domesticum sebagai Agen Antimalaria Potensial yang Menargetkan Enzim Laktat Dehidrogenase (PfLDH) pada Plasmodium falciparum Hanum, Laila; Nirwana, Rahma Julia; Oktariansyah, Yadi; Harvianti, Yuniar
Biogenesis: Jurnal Ilmiah Biologi Vol 14 No 1 (2026)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v14i1.62225

Abstract

Malaria continues to be a significant global infectious illness, with Plasmodium falciparum primarily responsible for the most severe and lethal cases, including cerebral malaria. P. falciparum lactate dehydrogenase (PfLDH), an essential enzyme in the parasite's glycolytic cycle, is a viable molecular target for the development of antimalarial drugs. The deficiencies in existing therapeutics underscore the necessity for novel candidate alternative drugs. Lansium domesticum, a native Indonesian plant, possesses bioactive compounds with potential antimalarial effects. This work sought to assess L. domesticum secondary metabolites as potential antimalarial agents using an in silico methodology. A total of 47 compounds were evaluated to forecast antimalarial efficacy, thereafter, assessing their physicochemical attributes, pharmacokinetic features, and toxicity profiles. Molecular docking was used to examine the interactions between potential drugs and the PfLDH target enzyme. Four compounds—is-3-Hexen-1-ol, Aromadendrene, Isoledene, and Hexadecanoic acid—fulfilled the necessary physicochemical, pharmacokinetic, and toxicological standards. Hexadecanoic acid demonstrated the most robust interaction with PfLDH, establishing three critical amino acid connections at the active site (GLY29, THR97, and HIS195) and exhibiting a superior binding affinity compared to control and natural ligands. The data indicate that hexadecanoic acid is a promising antimalarial candidate sourced from L. domesticum. Additional molecular dynamics simulations, together with in vitro and in vivo investigations, are required to validate its therapeutic efficacy.
From Illumination to Biological Regulation: A Biological Reappraisal of Lighting Management in Chickens – A Review Yadi Oktariansyah; Ferta Liza Putri
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11515

Abstract

Lighting management is a fundamental component of chicken production systems and has traditionally been applied as a technical tool to enhance activity, feeding behavior, and productivity. Increasing evidence, however, indicates that light functions not merely as illumination, but as a key biological signal regulating circadian rhythms, neuroendocrine pathways, behavior, welfare, and long-term production performance. This review provides a biological reappraisal of lighting management in chickens by synthesizing current evidence on how different lighting characteristics influence biological regulation and practical outcomes. A systematic literature review was conducted following PRISMA guidelines, with a qualitative synthesis approach adopted due to heterogeneity in study designs, lighting protocols, and outcome measures. Evidence was integrated across major lighting domains, including photoperiod duration, timing consistency, light intensity, spatial distribution, spectral composition, lighting technology, and stage-specific implementation. Emphasis was placed on identifying primary biological targets, expected production benefits, risks of mismanagement, and relevant monitoring indicators. The synthesized findings demonstrate that lighting management acts primarily through alignment with endogenous circadian and endocrine systems rather than isolated technical parameters. Lighting regimes that preserve circadian stability support sustainable productivity and animal welfare, whereas biologically inappropriate strategies may induce cumulative physiological stress and compromise long-term performance. This review highlights the need to reframe lighting management as a form of biological regulation to support data-driven and biologically informed production systems.
PENINGKATAN SKILL SISWA TUNARUNGU MELALUI PELATIHAN PATCHWORK DAN QUILTING BERBASIS APLIKASI SIGN TALK DI SLB-B YPAC PALEMBANG Anita Desiani; Bambang Suprihatin; Ali Amran; Yadi Oktariansyah; Siti Rusdiana Puspa Dewi; Jonatan Jonatan; Slamet Prayogo; Lonamonika Sinabutar
Jurnal AbdiMas Nusa Mandiri Vol. 8 No. 2 (2026): Periode April 2026
Publisher : LPPM Universitas Nusa Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33480/abdimas.v8i2.7965

Abstract

Skill development for deaf students at SLB-B YPAC Palembang still faces significant challenges, particularly due to communication barriers between teachers and students that hinder knowledge transfer. This community service program aims to enhance hard skills (technical sewing skills in patchwork and quilting) as well as soft skills (communication, teamwork, and independence) through the integration of an Artificial Intelligence (AI)-based application called Sign Talk. The implementation method was carried out through a workshop and intensive mentoring scheme over 4 months, which included 3 main training sessions, each lasting 120 minutes, for 15 deaf students. Evaluation was conducted using pre-test and post-test instruments analyzed descriptively. The results of the activity showed an increase in students’ soft skills of 40.5%. For hard skills, specifically sewing competencies, there was a 23.31% increase. Although 90% of participants rated the Sign Talk application as very helpful in understanding instructions during the activity, further development of the Sign Talk vocabulary is needed. Additionally, this activity can be expanded to include other hard skill trainings with Sign Talk serving as the communication medium.
Edukasi Pencegahan Penularan Penyakit Tuberkulosis Pada Masyarakat Sekitar Pembakaran Arang Informal Desa Dapur 12 Batam Yuanita Windusari; Ladyka Viola Aulia Armawan; Swara Mega Hasanah; Yoerdy Agusmal Saputra; Yadi Oktariansyah
Jurnal Pengabdian Masyarakat Aufa (JPMA) Vol. 8 No. 2 (2026): Vol 8 No. 2 Agustus 2026
Publisher : Universitas Aufa Royhan Di Kota Padangsidipuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51933/jpma.v8i2.2893

Abstract

Tuberkulosis (TB) masih menjadi salah satu masalah kesehatan masyarakat di Indonesia. Masyarakat yang tinggal di sekitar lokasi pembakaran arang informal berpotensi mengalami paparan asap biomassa yang dapat meningkatkan kerentanan terhadap gangguan saluran pernapasan, sehingga diperlukan upaya promotif melalui edukasi kesehatan. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan masyarakat mengenai pencegahan penularan tuberkulosis di Desa Dapur 12, Kota Batam. Kegiatan dilaksanakan pada 27 peserta melalui beberapa tahapan, yaitu persiapan, pelaksanaan pre-test, penyampaian materi edukasi menggunakan metode ceramah dan leaflet, diskusi interaktif, pelaksanaan post-test, serta evaluasi. Efektivitas edukasi dianalisis menggunakan uji Wilcoxon Signed-Rank karena data tidak berdistribusi normal. Hasil menunjukkan adanya peningkatan rata-rata skor pengetahuan peserta dari 4,48 pada saat pre-test menjadi 8,04 pada saat post-test. Hasil uji Wilcoxon menunjukkan perbedaan yang bermakna antara skor pengetahuan sebelum dan sesudah edukasi (Z = -4,658; p = 0,0001). Peningkatan pengetahuan ini menunjukkan bahwa edukasi kesehatan yang dilakukan secara interaktif mampu meningkatkan pemahaman masyarakat mengenai cara penularan, faktor risiko, dan upaya pencegahan tuberkulosis. Kegiatan edukasi kesehatan terbukti efektif meningkatkan pengetahuan masyarakat dan berpotensi mendukung upaya promotif dalam pengendalian tuberkulosis pada masyarakat yang tinggal di sekitar pembakaran arang informal.
Co-Authors Afni Salhsa Billa Ali Amran Amrillah Nugrasyah Anita Desiani Ario Sucipto Artika Sri Wahyuni Arum Setiawan Arum Setiawan Arum Setiawan Ayu Safitri Bambang Suprihatin Cahyani, Riski Desitarani Doni Setiawan Doni Setiawan Elffisa Eriani Elisa Nurnawati Elisa Nurnawati Endri Junaidi Enggar Patriono Eva Musifa Febrian Hadinata Ferta Liza Putri Ferta Liza Putri Harvianti, Yuniar Hary Widjajanti Hary Widjajanti Huda, Muhammad Komarul Indra Yustian Iqbar, Muhammad Jonatan Jonatan Khairatul Hasanah Ladyka Viola Aulia Armawan LAILA HANUM LAILA HANUM Laila Hanum Laila Hanum Laila Hanum Hanum Lonamonika Sinabutar Masito Masito Masito, Masito Muhammad Habiburrahman Muhammad Ikhsan Muharni Muharni Mustafa Kamal Mustafa Kamal Mustafa Kamal Nayla Khairani Nirwana, Rahma Julia Novira, Sandra Nur Fatimah Vita Sari Patricia, Margareth Pragustiandi, Guntur Pranoto, Aidil Fitra Putri, Cyntia Sabarani Ramadhani, Audya Rahma SALWA GHANIYU USMAN Sarah Angelica W. Simamora Sarno . Singgih Tri Wardhana Siti Rusdiana Puspa Dewi Slamet Prayogo Swara Mega Hasanah TUTIK WAHYUNI Yoerdy Agusmal Saputra Yuanita Windusari Yuniar Harvianti Yuniar Harvianti Yuniar Harvianti Yuniar Harvianti Zainal Fanani