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All Journal Jurnal Farmasi Sains dan Komunitas Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Journal Of Vocational Health Studies Jurnal SOLMA PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Media Karya Kesehatan Poltekita: Jurnal Pengabdian Masyarakat Warta LPM Journal of Tropical Pharmacy and Chemistry

Dicki Bakhtiar Purkon

Poltekkes Kemenkes Bandung

Author-ID : 8478948

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Peningkatan Pemahaman dan Keterampilan Mitra Posbindu Kelurahan Cimahi Utara Kota Cimahi dalam Pembuatan Minuman Tradisional Herbal sebagai Imunostimulan Dicki Bakhtiar Purkon; Mimin Kusmiyati; Elvi Trinovani; Faizah Min Fadhlillah
Jurnal SOLMA Vol. 10 No. 2 (2021)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v10i2.6270

Background: Peranan imunostimulan yang merupakan produk nutrisi/ obat (bahan alam/ sintetik) yang dapat meningkatkan sistem imunitas tubuh menjadi anjuran oleh pihak tenaga kesehatan dan pemerintah kepada masyarakat untuk dikonsumsi secara rutin. Perlu dilakukan pemberian informasi/ wawasan kesehatan untuk meningkatkan pemahaman imunostimulan, pemanfaatan herbal dan keterampilan pembuatan minuman tradisional herbal sebagai imunostimulan. Metode: Kegiatan ini dilaksanakan di Gedung Serba Guna (GSG) RW. 04 Komplek Cimindi Raya, Kel. Cimahi Utara, Kota Cimahi, Jawa Barat dengan jumlah peserta mitra Posbindu 30 orang. Kegiatan yang dilaksanakan berupa penyuluhan, demonstrasi dan diskusi dengan para mitra. Perubahan pemahaman dan keterampilan mitra Posbindu dievaluasi melalui hasil kuesioner pre-test dan post-test selama penyuluhan dilaksanakan. Hasil: Mitra Posbindu sudah meningkat pemahamannya mengenai materi kesehatan imunostimulan dan cara pembuatan minuman tradisional herbal sebagai imunostimulan dengan perolehan peningkatan skor rata-rata pengetahuan melebihi batas skor minimal yaitu 76,43 % dan peningkatan skor keterampilan yaitu 95,71% (batas skor minimal yaitu 60%). Kesimpulan: Kegiatan ini menjadi upaya meningkatkan daya tahan tubuh, jumlah kesembuhan pasien yang terpapar virus Covid-19/ infektor patogen lain dan mencegah kematian yang diakibatkan menurunnya sistem imunitas pada mitra Posbindu khususnya dan masyarakat secara umum.

Assistance in Skills Training for Making Herbal Mouthwash Green Tea Leaves and Its Herbal Combinations for Posbindu Partner Cadre Dicki Bakhtiar Purkon; Mimin Kusmiyati; Elvi Trinovani; Faizah Min Fadhlillah; Yayat Sudaryat; Zahra Anggraeni; Tanika Miatul Hadid; Afifah Rahmawati
Media Karya Kesehatan Vol 5, No 2 (2022): Media Karya Kesehatan
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mkk.v5i2.37955

The level of knowledge and awareness of the Indonesian people towards preventive efforts of various diseases related to the oral cavity and teeth has not been optimal. The importance of the role of self-effort in optimizing oral cavity hygiene and inhibiting the growth of various types of harmful bacteria that can lead to plaque formation, dental caries, causes of gingivitis, and periodontitis, such as: bacterial species Streptococcus mutans and Porphyromonas gingivalis. The combination of green tea, cloves, cinnamon bark, and mint leaves containing secondary metabolites from the sterols, tannins, phenols, saponins, and flavonoids groups has traditionally been used as antibacterial, anti-plaque and anti-aviation. The purpose of this community service activity is to improve understanding of health and prevention of infections in the oral cavity and teeth, as well as assistance in training skills in making herbal combination mouthwash with simple formulations for Posbindu partners. This activity was attended by lecturers and students of the D-3 Pharmacy Study Program, Department of Pharmacy, Poltekkes Kemenkes Bandung. Changes in health knowledge and skills of Posbindu partners were evaluated by giving pre-test and post-test questions. In the results of the evaluation of health understanding and skills, there was an increase in the total score of Posbindu partners in the 1st session of 20.41% from 67.35% to 87.76% (14 people were achieved, initially only 7 people exceeded the minimum score limit of 60.00%; N=14). Meanwhile, in the second session of Posbindu partners, the score increased by 28.57% from 63.64% (pre-test) to 92.21% (post-test) with the number of people who exceeded the minimum score limit of 11 people (post-test) from the pre-test results. the previous test was only 5 people (N=11). Thus, the better the health knowledge, attitudes, and skills of Posbindu partners in processing various herbal ingredients into herbal mouthwash products, it will create an increase in the degree of oral and dental health for the community. Keywords: Cloves, green tea leaves, mint leaves, cinnamon bark, herbal mouthwash.

Pelatihan Pembuatan Masker Wajah Tipe Peel-Off dari Herba Lumut Hati Marchantia paleacea dan Daun Teh Hijau kepada Mitra Posbindu Dicki Bakhtiar Purkon; Mimin Kusmiyati; Elvi Trinovani; Zahwa Ainunnisya Nur Aisyah; Nizella Syahla; Ansyirohanisa Ansyirohanisa; Vindi Nur Amalia; Faizah Min Fadhlillah
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 2 (2023): April-Juni
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Peel-off type facial skin mask preparations from herbal/synthetic ingredients can have the advantages of being easily removed, such as elastic membranes, improving hydration of the skin, treating wrinkles, aging, and acne, shrinking pores, moisturizing the skin, and relaxing facial muscles. Posbindu partner cadres in the working area of Puskesmas Pasirkaliki, Cimahi City, feel that there is still a lack of understanding and skill level in making simple cosmetic preparations from herbal ingredients, especially peel-off type facial skin mask preparations. Thus, we, as an extension team from the Community Partnership Program (PKM) grant scheme, strive to provide booklets, counseling on various facial skin health materials, and training assistance in making peel-off type facial skin masks with simple formulations of a combination of Marchantia paleacea liver moss herbaceous plants and green tea leaves to posbindu partner cadres in the Pasirkaliki Puskesmas Working Area, North Cimahi Village, Cimahi City. The mixed results of this community service activity indicate that there are benefits, such as a significant increase in the level of health understanding in the results of pre-test and post-test evaluations of various health education that have been provided, including the importance of utilizing peel-off type facial skin mask preparations from traditional herbal ingredients and Posbindu partner cadres as agents of change are expected to convey health information and skills that obtained so that it can be conveyed to the immediate family and the rest of the community in general

Pemberdayaan Kelompok PKK dan Kampung KB dalam Implementasi Protokol Kesehatan, Vaksinasi, dan Pola Hidup Bersih Sehat untuk Memutus Penyebaran Covid-19 Osman Syarief; Irmawartini Irmawartini; Dicki Bakhtiar Purkon; Ali Hamzah; Nandang Ahmad Waluya
Warta LPM WARTA LPM, Vol. 25, No. 4, Oktober 2022
Publisher : Universitas Muhammadiyah Surakarta

The condition of the Covid-19 pandemic with various variant genetic mutations and severe manifestations can pose a risk of death with a relatively high transmission rate throughout the world. Moreover, the level of public awareness of compliance with health protocols and a clean and healthy lifestyle (PHBS), is still low from various survey results in Indonesia, including the Palasari and Cipadung Villages (Cibiru District), Bandung City, West Java. This community service activity aims to increase public health awareness and skills, especially community organization cadres as role models for other communities, such as PKK (Family Empowerment and Welfare) groups and KB (Family Planning) Villages with the Interprofessional Education (IPE) method conducted by a team of extension workers with various health science backgrounds with a series of activities that include: counselling on various health materials such as a clean and healthy lifestyle (PHBS), socialization of health protocols and self-isolation, mentoring on medical mask waste management, and how to make traditional herbal drinks as an immunomodulator (immunostimulant) to prevent/minimize the transmission of Covid-19. The entire counselling material was provided comprehensively to prevent the transmission of Covid-19 from various aspects, including aspects of nutrition, environmental health, 2000, and pharmaceuticals. The results achieved are the implementation of counselling on the introduction of Covid-19 and its various variants, prevention of Covid-19 from various health aspects, socialization of the application of health protocols, self-isolation, government vaccination programs, medical waste management, and how to make traditional drinks to improve the immune system in our body. The community service activities for Posbindu partner cadres in 2 Kelurahan were successfully implemented and could improve the understanding of health, attitudes, and behaviour of all Posbindu partner cadres by looking at the increase in the results of pre-test and post-test evaluations so that Posbindu partner cadres as part of change agents can distribute health information obtained to the public.

Pendampingan Pelatihan Pembuatan Minuman Herbal Sediaan Teh Celup dari Daun Salam dan Kombinasi Herbalnya, serta Pemeriksaan Tekanan dan Kadar Gula Darah pada Mitra Kelompok PKK di Kelurahan Palasari Kecamatan Cibiru Dicki Bakhtiar Purkon; Elvi Trinovani; Irvan Herdiana; Ansyirohanisa Ansyirohanisa; Nizella Syahla; Nelly Selvatiany; Natasya Khairunnisa; Muhammad Aqil Zaelani; Imas Siti Nur Padilah; Khaira Arnella; Faizah Min Fadhlillah; Lilis Febriyanti
Jurnal SOLMA Vol. 12 No. 3 (2023)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v12i3.13005

Pendahuluan: Data survei kesehatan Nasional menunjukkan peningkatan lebih dari 30% pada kasus hipertensi dan diabetes pada usia dewasa dan lanjut usia. Daun salam (Syzygium polyanthum) digunakan untuk mengobati kedua penyakit ini. Penelitian ini fokus pada pemberdayaan kader PKK di Kelurahan Palasari Kecamatan Cibiru untuk pemeriksaan tekanan darah, kadar gula darah, serta pelatihan pembuatan teh celup dari daun salam. Metode: Metode yang digunakan meliputi pembagian booklet, penyuluhan TOGA, dan kombinasi daun salam dengan herbal antihipertensi dan antihiperglikemik. Hasil: Booklet, video, dan peningkatan pemahaman kesehatan dari pre-test dan post-test. Kesimpulan: Partisipasi aktif kader PKK bisa efektif dalam pencegahan dan penanganan penyakit degeneratif, terutama dengan penggunaan minuman herbal daun salam dan herbal kombinasi.

Determination of Phenolic and Flavonoid Total Levels and Antioxidant Activity of Ethanol, Ethyl Acetate, and n-Hexane Extracts of Citrus reticulata Blanco Fruit Peel by DPPH and ABTS Methods: Penetapan Kadar Total Fenol dan Flavonoid serta Aktivitas Antioksidan Ekstrak Etanol, Etil Asetat, dan n-Heksan Kulit Buah Citrus reticulata Blanco dengan Metode DPPH dan ABTS Fadhlillah, Faizah Min; Miranti, Mila; Wibowo, Diki Prayugo; Purkon, Dicki Bakhtiar
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.16399

Background: The peel of the fruit Citrus reticulata Blanco has long been used in traditional medicine due to its various properties. Traditional medicine from certain parts of medicinal plants is related to the content of bioactive compounds from the fruit's peel, such as phenolic compounds and flavonoids that can help protect the body from damage caused by free radicals. Objectives: This study aimed to evaluate the total levels of phenolics and flavonoids as well as antioxidants from ethanol, ethyl acetate, and n-hexane extracts from the skin of Citrus reticulata Blanco using DPPH (2,2-diphenyl-1-picrylhydrazil) and ABTS (2,2'-azinobis-(3-ethylbenzothiazolin-6-sulphonate))) methods. Material and Methods: The extraction process was carried out using the maceration ion method with ethanol, ethyl acetate, and n-hexane solvents at room temperature for 24 hours. Total phenolic and flavonoid levels in the extract were determined using UV-Vis spectrophotometry, and antioxidant activity testing was determined based on the extract's ability to neutralize free radicals from DPPH and ABTS. Results: The results showed that the ethanol extract of Citrus reticulata Blanco fruit peel had higher total phenolic and flavonoid levels compared to ethyl acetate and n-hexane extracts. The total phenolic levels in ethanol, ethyl acetate, and n-hexane extracts were 142.02, 74.60, and 57.17 mg GAE/g, respectively. The total flavonoid levels in ethanol, ethyl acetate, and n-hexane extracts were 45.96, 40.22, and 38.54 mg QE/g, respectively. In addition, ethanol extract has also shown the strongest antioxidant activity based on the results of testing with DPPH and ABTS methods. The inhibitory concentration (IC50) of ethanol extract against DPPH and ABTS methods was 23,490 Î¼g/mL and 31,971 Î¼g/mL, respectively, with strong category. Conclusions: This study shows that the skin of Citrus reticulata Blanco fruit contains phenolic compounds and flavonoids that have the potential as natural antioxidants, with ethanol extract being the most promising related to total phenolic and flavonoid levels and antioxidant activity. This information can be used as a basis for developing pharmaceutical dosage products and health supplements that can potentially improve antioxidant/health status in the body.

PHYTOCHEMICAL, USE IN ETHNOMEDICINE, AND THERAPEUTIC ACTIVITIES OF MARCHANTIA GENUS Purkon, Dicki Bakhtiar; Fadhlillah, Faizah Min; Maigoda, Tonny Cortis; Iwo, Maria Immaculata; Soemardji, Adreanus Andaja; Nadhifah, Ainun; Sudaryat, Yayat
Journal of Vocational Health Studies Vol. 5 No. 3 (2022): March 2022 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V5.I3.2022.174-185

Background: Liverworts are a group of plants from the Marchantia genus containing various biologically active compounds and comprised of 65 species worldwide. This plant species belongs to the Marchantiaceae family, which was used empirically in China, North America, Ancient Greece, and Indonesia to treat open wounds, burns, hepatotoxicity, and infection prevention. Now, liverworts have great potential as medicinal and nutraceutical products because of their phytochemical content and diversity of pharmacological activities. Purpose: This review focuses on secondary metabolites obtained from the thalloid and whole plant parts (herbs) and the compilation of their pharmacological activities, which are still poorly documented. Review: This review article obtained related information through extensive international journals (online) scientific databases and offline (books) related to all searches of the species of the genus Marchantia which included: phytochemical content (secondary metabolites) and various pharmacological activities which were collected and compared all results of literature studies from various aspects. Some of the secondary metabolites are Marchantin A, B, D dan E; Paleatin B; Perrottetin F, and Plagiochin E, which have various pharmacological activities. Various results regarding all the therapeutic properties of the genus Marchantia have been produced in the world such as: antibacterial, antifungal, antioxidant, cytotoxic activity, anti-inflammatory, cardiotonic, hepatoprotective, muscle relaxant, antiosteoporosis, and skin care. Conclusion: Therefore, the potential for the development of medicinal, supplementary and nutraceutical products from various Marchantia species is very large and broad for the future.

Antithrombotic and Antioxidant Activities of Binahong [Anredera cordifolia (Ten.) Steenis] Leaf Ethanol Extract and Its Nanoemulsion Preparation in Swiss Webster Mice Maria Immaculata Iwo; Amirah Adlia; Silviyanita Isna Septila; Yennie Agnes Pratama; Dicki Bakhtiar Purkon
Journal of Tropical Pharmacy and Chemistry Vol. 6 No. 2 (2022): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v6i2.516

Platelet aggregation has the potential to form thrombi and result in cardiovascular system diseases such as myocardial infarction and ischemic stroke - one of the leading causes of death globally. Traditionally, people use binahong leaves as blood thinners. Therefore, this study aims to obtain scientific data on the efficacy of binahong leaf as antithrombotic. The efficacy test was carried out on male Swiss-Webster mice. The results showed that the ethanol extract of binahong leaves at doses of 50 (BLEE50) and 100 mg/kg bw (BLEE100) could increase bleeding time on H7 (7.61±1.79% and 3.72±1.76% vs 1.08±0.90%) and H14 (13.81±4.42% and 5.06±2.30% vs 1.66±1.09%) and coagulation time at H7 (5.01±1.36% and 4.18±1.67% vs 1.38±1.08%) and at H14 (7.92±1.97% and 7.19±1.96% vs 1.70±1.10%) significantly (p<0.05). The two doses of BLEE were formulated in the form of nanoemulsions with the Self Nano Emulsifying Drug Delivery System (NBLEE50 and NBLEE100) were also able to prolong bleeding time and coagulation time significantly (p<0.01) but only NBLEE50 prolonged bleeding time (p<0.05) significantly against BLEE50. In the test of the anti-platelet aggregation effect with ADP as an inducer, both doses of BLEE and the nanoemulsion preparation (NBLEE) could significantly (p<0.01) inhibit platelet aggregation with a percentage of inhibition >70% which was not different from the standard (acetylsalicylic acid). In the antioxidant effect test using the DPPH method, BLEE has an IC50 = 66.08?g/mL which is classified as a strong antioxidant. Both doses of BLEE and its NBLEE could significantly (p<0.01) inhibit lipid peroxidation in plasma and liver and NO radicals formation. BLEE50 can significantly (p<0.05) reduce mean platelet volume (6.05±0.24fL vs 6.55±0.34fL) and platelet distribution width (8.52±0.36% vs 9.25±0.42%). Based on those results, BLEE has the potential to be used as an antiplatelet aggregation and antioxidant.

Antihyperlipidemic activity of Marchantia paleacea herb and Zingiber officinale var. Rubrum rhizome ethanol extracts in Triton X-100-induced mice Purkon, Dicki Bakhtiar; Ningsih, Padmasari Diah Ayu Kumala; Pambudi, Fatimah Ayu Putri; Widyastiwi, Widyastiwi; Roseno, M.H.; Haerussana, Ayu Nala El Muna; Fadhlillah, Faizah Min; Trinovani, Elvi
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 2 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i2.1458

Non-communicable diseases cause 71% of deaths in the world, one of which is caused by dyslipidemia. Dyslipidemia has been established as a cause of various non-communicable diseases such as obesity and heart disease. This study aims to determine the antihyperlipidemic activity of the ethanol extract of the liverworts of Marchantia paleacea (EEMP) and the rhizome of Zingiber officinale var. rubrum (EEZOR) on male mice induced by Triton X-100. Grouping the number of test animals per group based on the Federer formula. Triton X-100 is used as an inducer of hyperlipidemic given intraperitoneally at a dose of 140 mg/kg body weight. Total cholesterol levels were measured by the colorimetric enzymatic method (CHOD-PAP) using a UV-Vis clinic photometer. Results from ethanol extract of the herb liverwort Marchantia paleacea (EEMP) and red ginger rhizomes Zingiber officinale var. Rubrum (EEZOR) can respectively reduce total hypercholesterol levels in male mice induced by Triton X-100 whose data were analyzed using the One-Way Anova test. The results of optimal dose of EEMP 200 mg/kg bw had the highest percentage of antihyperlipidemic activity and effectiveness (%) and also had a significant reduction in total cholesterol levels compared to the negative control group (p<0.05). While the results for the optimal dose of EEZOR 1000 mg/kg bw with the highest percentage of activity and effectiveness (%) and having a significant decrease compared to the negative control group (p <0.05). In conclusion, these findings suggest that both extracts have potential as natural antihyperlipidemic agents that can be further explored in the management of hyperlipidemic (dyslipidemic) and related non-communicable diseases.

Pemanfaatan Teh Hijau sebagai Obat Kumur dalam Upaya Peningkatan Perekonomian Masyarakat Desa Talagasari dan Sindangsari: Utilization of Green Tea as Mouthwash in an Effort to Improve the Economy of the Talagasari and Sindangsari Village Communities Kusmiyati, Mimin; Novani, Elvi Tri; Widyastuti, Tri; Purkon, Dicki Bakhtiar; Herdiana, Irvan; Noviapratami, Nikky; Fatimah, Cucu
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 4 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i4.8877

Gingivitis is an oral health disease characterized by inflammation of the gingival tissue that appears reddish. One way to prevent and treat gingivitis is to use mouthwash. Green tea herbal mouthwash is used to treat gingivitis. Green tea is known to have antimicrobial activity that causes gingivitis. The increase in public knowledge about green tea mouthwash increased by 41%. This shows public understanding of the benefits of green tea mouthwash for preventing gingivitis and the economic value of green tea herbal mouthwash products.

Co-Authors Afifah Rahmawati Agustin, Himeliya Ainun Nadhifah, Ainun Ali Hamzah Amirah Adlia Ansyirohanisa Ansyirohanisa Ansyirohanisa Ansyirohanisa Elvi Trinovani Elvi Trinovani, Elvi Faizah Min Fadhlillah Fatimah, Cucu Haerussana, Ayu Nala El Muna Hotimah, Alni Khusnul Imas Siti Nur Padilah Irmawartini Irmawartini Irvan Herdiana Irvan Herdiana Khaira Arnella Lilis Febriyanti Maigoda, Tonny Cortis Maria Immaculata Iwo Maria Immaculata Iwo Mimin Kusmiyati, Mimin Miranti, Mila Muhammad Aqil Zaelani Nainggolan, Aurelya Veny Kurnia Nandang Ahmad Waluya Natasya Khairunnisa Nelly Selvatiany Ningsih, Padmasari Diah Ayu Kumala Nizella Syahla Nizella Syahla Novani, Elvi Tri Noviapratami, Nikky Osman Syarief Pambudi, Fatimah Ayu Putri Roseno, M.H. Silviyanita Isna Septila Soemardji, Adreanus Andaja Srinati, Ine Sufa, Hafizah Ilmi Tanika Miatul Hadid Tri Widyastuti Vindi Nur Amalia Wibowo, Diki Prayugo Yayat Sudaryat Yennie Agnes Pratama Zahra Anggraeni Zahwa Ainunnisya Nur Aisyah

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