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All Journal Jurnal Teknik Kimia USU AL KAUNIYAH Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Jurnal Psikologi Biology, Medicine, & Natural Product Chemistry BIOMA International Journal of Applied Biology JRST (Jurnal Riset Sains dan Teknologi) Journal of Health Science and Prevention Indonesian Journal for Health Sciences (IJHS) Scripta Biologica Al-Ard: Jurnal Teknik Lingkungan Jurnal Abdimas Ilmiah Citra Bakti (JAICB) PROFESI (Profesional Islam): Media Publikasi Penelitian Jurnal Mandala Pengabdian Masyarakat JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Jurnal Abdimas Bina Bangsa Jurnal Teknologi Kesehatan Jurnal Pemberdayaan Masyarakat Indonesia (JPMI) Jurnal Teknik Kimia USU Gema Kesehatan Engagement: Jurnal Pengabdian Kepada Masyarakat BIOTROPIC
Funsu Andiarna
Universitas Islam Negeri Sunan Ampel Surabaya
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Formulation and Characterization Tests of SCOBY Kombucha Gel Agustina, Eva; Nafisah, Raihana Frika; Fiddaroini, Achmad Farchan; Tania, Clarista Eka; Purnamasari, Risa; Andiarna, Funsu; Hidayati, Irul
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.143-151

Abstract

The wound is the damage to body tissues caused by various factors such as accidents, sharp object scratches, etc. Proper care is necessary to accelerate the wound healing process. Topical medications, such as gel preparations, are commonly used for wounds. Kombucha SCOBY is believed to contain bioactive compounds that can accelerate the wound healing process, making it a potential active ingredient in gel preparations. This research aims to determine the characteristics of kombucha SCOBY gel with various concentration variations. SCOBY is obtained from kombucha fermentation using green tea, sugar, and kombucha culture. Preparing kombucha SCOBY gel involves using carbomer 940, methyl paraben, triethanolamine, glycerin, and SCOBY kombucha. The concentration variations of kombucha SCOBY gel include 0%, 2%, 4%, 8%, 10%, and 12%. Each formula undergoes physical characteristic tests including an organoleptic test, hedonic test, homogeneity test, pH test, spreadability test, and adhesiveness test. Data obtained after physical characteristic tests of the gel preparations are analyzed descriptively. Based on the conducted research, it was found that kombucha SCOBY gel preparations with concentration variations of 0%, 2%, 4%, 8%, 10%, and 12% exhibited different characteristics. The higher the gel concentration, the more acidic the gel's aroma, the more liquid the texture, and the more intense the color. SCOBY added to the gel preparation can increase the pH value, adhesiveness, and spreadability of the gel.
Effect of Variation in Concentration of SCOBY Kombucha Gel Citrus Peel Extract (Citrus nobilis) on Wound Incision (Vulnus Scissum) in Mice (Mus musculus) Shofiyya, Ainina Neihayatus; Eva Agustina; Funsu Andiarna; Irul Hidayati; Risa Purnamasari
International Journal of Applied Biology Vol. 9 No. 1 (2025): International Journal of Applied Biology
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A laceration wound is damage to the skin tissue characterized by a neat outline of the wound edge, due to slices by sharp instruments or incisions during surgery. This study aims to evaluate the effect of variations in the concentration of SCOBY Kombucha gel preparations of orange peel extract (Citrus nobilis) on wound healing (Vulnus Scissum) in mice (Mus musculus). SCOBY Kombucha gel was made with six concentration variations (0%, 2%, 4%, 8%, 10%, and 12%) and tested for its effectiveness in accelerating wound healing. The research method involved making incision wounds on male mice, followed by applying the gel according to the specified concentrations. The results showed that SCOBY Kombucha gel with a concentration of 12% was most effective in accelerating wound healing, approaching the effectiveness of the positive control (bioplacenton). Analysis showed that the increase in gel concentration was directly proportional to the effectiveness of wound healing, where higher concentration gels showed significantly faster wound closure.
IDENTIFIKASI SENYAWA METABOLIT SEKUNDER PADA EKSTRAK METHANOL BATANG KEMANGI (Ocimum bacilicum L): IDENTIFICATION OF SECONDARY METABOLYTE IN METHANOL EXTRACT OF BASIL STEMS (Ocimum bacilicum L) Andiarna, Funsu; Kumalasari, Mei Lina Fitri; Tyastirin, Esti; Pribadi, Eko Teguh; Khoiriyah, Romyun Alvy; Oktorina, Sarita
GEMA KESEHATAN Vol. 15 No. 2 (2023): Desember 2023
Publisher : POLTEKKES KEMENKES JAYAPURA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47539/gk.v15i2.420

Abstract

Tanaman kemangi (Ocimum bacilicum L) adalah salah satu tanaman obat tradisional yang paling banyak dikembangkan di negara Indonesia. Tanaman kemangi memiliki banyak manfaat seperti mengobati demam, diare, batuk, pusing, mual, dan lain sebagainya. Tujuan dari penelitian ini untuk mengidentifikasi senyawa metabolit sekunder pada batang tanaman kemangi. Ekstrak kemangi menggunakan pelarut metanol 96%. Batang daun kemangi dilakukan proses penyarian dengan metode maserasi. Ekstrak kemangi selanjutnya dilakukan uji fitokimia untuk mengetahui kandungan senyawa metabolit sekunder. Hasil dari penelitian ini menunjukkan bahwa pada batang tanaman kemangi terdapat kandungan senyawa metabolit sekunder yaitu flavonoid, tannin, alkaloid dan saponin. Hal ini dapat menjelaskan bahwa ekstrak kemangi memiliki potensi yang kuat dalam aktivitas antioksidan yang memiliki peran penting dalam pemanfaatan obat tradisional. Senyawa flavonoid paling umum dijadikan sebagai antioksidan. Selain itu beberapa jenis senyawa alkaloid, tanin dan saponin juga mempunyai efek antioksidan. Kata Kunci: Kemangi,  Metanol,  Ocimum bacilicum L, Senyawa metabolit sekunder   The basil plant (Ocimum bacilicum L) is one of Indonesia's most developed traditional medicinal plants. Basil plants have many benefits, such as treating fever, diarrhea, cough, dizziness, nausea, etc. The study aims to identify secondary metabolite compounds in the stem of basil plants. Basil extract uses 96% methanol solvent. Stems of basil leaves carried out the process of expulsion by maceration method. The phytochemical test was conducted through basil extraction to determine the secondary content of metabolite compounds. The results of this research show that the stem of the basil plant is a secondary metabolite compound, namely flavonoids, alkaloids, tannins, and saponins. It can explain that basil extract has a strong potential for antioxidant activity that has an essential role in traditional medicine. Keywords: Methanol, Ocimum bacilicum, Secondary metabolites compounds, Stem basil
Analisis Penggunaan Media Sosial Terhadap Kejadian Insomnia Pada Mahasiswa Andiarna, Funsu; Prasetyaning Widayanti, Linda; Hidayati, Irul; Agustina, Eva
Profesi (Profesional Islam) : Media Publikasi Penelitian Vol. 17 No. 2 (2020): Profesi (Profesional Islam) : Media Publikasi Penelitian
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) ITS PKU Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26576/profesi.v17i2.26

Abstract

Internet merupakan hasil kemajuan teknologi yang semakin pesat sudah menjadi kebutuhan setiap orang. Internet memudahkan setiap orang mengakses semua informasi yang dibutuhkan dengan lebih cepat, efektif dan efisien, mempermudah komunikasi tanpa terbatas waktu dan tempat. Media sosial merupakan salah satu media yang sekarang ini menjadi kebutuhan bagi setiap orang. Penggunaan media sosial memiliki dampak positif dan negatif. Dampak positif tentunya dapat dijadikan sebagai sarana menambah wawasan, meningkatkan keterampilan serta menumbuhkan kepedulian terhadap sesama. Penelitian ini bertujuan untuk menganalisis penggunaan media sosial terhadap kejadian insomnia pada mahasiswa. Jenis penelitian ini merupakan observasional analitik dengan pendekatan cross sectional. Penelitian ini dilakukan pada mahasiswa UIN Sunan Ampel Surabaya dengan jumlah sampel sebanyak 194 responden dengan teknik simple random sampling. Analisis data dalam penelitian ini menggunakan uji korelasi Spearman rank. Hasil penelitian menunjukkan terdapat hubungan antara penggunaan media sosial dengan kejadian insomnia (ρ=0,028) dengan kuat hubungan sangat lemah (R=0,158)
Potential of Black Garlic Nanoparticles as Skin Care Andiarna, Funsu; Hidayati, Irul; Agustina, Eva
Journal of Health Science and Prevention Vol. 8 No. 1 (2024): JHSP Vol 8 No 1 – 2024
Publisher : State Islamic University of Sunan Ampel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/jhsp.v8i1.1188

Abstract

Mask is a beauty product that serves to treat and maintain the skin of the body and face. Black garlic contains antioxidant compounds so that it can counteract free radicals that cause premature aging, wrinkled and dull skin. The purpose of this study was to determine the potential of black garlic nanoparticles as skin care. The aim of this research is to develop a face mask product based on black garlic nanoparticles. The research method is by extracting black garlic by maceration and making nanoparticles of black garlic extract with a silver reducing agent. Black garlic extract nanoparticles were substituted for the manufacture of peel-off masks and tested for their characteristic. The results showed that the black garlic nanoparticle mask had a strong antioxidant activity of 21.168 ppm, the particle size is 59.47 nm and had good characteristics as a peel-off mask based on the viscosity, spreadability, drying test. Black garlic masks with nano-sized particles are able to penetrate the skin's pores more effectively, thus aiding in the repair of damaged skin cells.
PENGARUH KOMPLEKS LINIER ALKYL BENZENE SULFONATE (LAS) DAN KADMIUM (Cd) TERHADAP PENINGKATAN AKUMULASI, ABSORBSI DAN TOKSISITAS KADMIUM (Cd) PADA Cyprinus carpio L. Hadi, Moch Irfan; Agustina, Eva; Andiarna, Funsu; Nadlir, Nadlir; Munir, Misbakhul
Al-Ard: Jurnal Teknik Lingkungan Vol. 4 No. 2 (2019): March
Publisher : Department of Environmental engineering, Faculty of Science and Technology, Islamic State University Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/alard.v4i2.477

Abstract

Deterjen merupakan salah satu hasil produk teknologi dengan menggunakan bahan kimia pengaktif permukaan (surfaktan) Alkyl Benzene Sulfonat (ABS) sebagai penghasil busa. ABS memiliki efek destruktif (buruk) terhadap lingkungan yakni sulit diuraikan oleh mikroorganisme, sehingga diganti dengan bahan aktif yang memiliki sifat lebih ramah lingkungan yaitu Linier Alkylbenzene Sulfonate (LAS). Tujuan penelitian adalah menganalisis pengaruh komplek Linier Alkyl Benzene Sulfonate (LAS) dan logam kadmium (Cd) dengan berbagai variasi konsentrasi terhadap absorbsi, akumulasi dan toksisitas logam kadmium (Cd) pada ikan mas (Cyprinus Carpio L). Sampel yang digunakan adalah ikan Cyprinus carpio L. dengan usia kurang lebih 3 bulan dengan asumsi bahwa ikan sudah berkembang secara seksual (mature). Cyprinus carpio L yang digunakan berkelamin jantan dengan panjang ±15cm dan berat badan ±100 gram. Penelitian ini menggunakan 6 variasi kelompok perlakuan dan 1 kelompok kontrol, maka dengan rumus diatas didapatkan r (ulangan) minimal 4 kali, maka dengan jumlah kelompokan 7 didapatkan besar sampel 28 ekor. Hasil penelitian ini adalah akumulasi lebih banyak ditemukan pada kelompok perlakuan Cd dan LAS. Kesimpulan dari hasil penelitian ini adalah didapatkan perbedaan akumulasi variasi perlakuan antara kelompok kontrol, Cd dan kombinasi LAS-Cd. Terjadinya akumulasi logam berat pada berbagai organisme dapat menimbulkan kerusakan pada lingkungan dan kesehatan pada manusia.
Effectiveness and Role of Symbiotic Culture of Bacteria and Yeast (SCOBY) Kombucha Gel on Incisional Wound Healing in Mice (Mus musculus) Nafisah, Raihana Frika; Agustina, Eva; Purnamasari, Risa; Andiarna, Funsu; Hidayati, Irul
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 3 (2025): October 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i3.11282

Abstract

Incision wounds are common occurrences in daily life, and appropriate wound management is essential to promote and accelerate the healing process. Wound care can be performed using topical preparations such as gels containing bioactive compounds. SCOBY kombucha is believed to contain bioactive compounds, such as compounds from green tea (especially polyphenols) and metabolites produced by microbes (organic acids, alcohols, vitamins, etc.) The aim of this research is to determine the effectiveness of SCOBY kombucha gel on the healing of incision wounds in mice (Mus musculus). The method used in this research is a Completely Randomized Design (CRD) with 8 treatment groups, including 2 control groups and 6 test groups. The concentrations of SCOBY kombucha gel used are 0%, 2%, 4%, 8%, 10%, and 12%. The SCOBY kombucha gel is applied twice daily until the wound closes. Observation of the incision wound is carried out by measuring the length of the wound that has not yet closed. Based on the conducted research, it was found that SCOBY kombucha gel is effective in healing incision wounds as evidenced by the reduction in wound size due to the bioactive compounds in SCOBY. The most significant wound healing effect was observed with the 12% SCOBY kombucha gel, as there was a significant difference compared to the negative control group, 0%, 2%, 4%, and 8% SCOBY kombucha gels.
Application of Symbiotic Culture of Bacteria and Yeast Kombucha Gel on Incision and Burn Wounds in Mice (Mus musculus): Aplikasi Gel Symbiotic Culture of Bacteria dan Yeast Kombucha pada Luka Sayat dan Bakar Mencit (Mus musculus) Andiarna, Funsu; Hidayati, Irul; Agustina, Eva; Purnamasari, Risa
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.24079

Abstract

SCOBY (Symbiotic Culture of Bacteria and Yeast) is a result of kombucha tea fermentation that contains active compounds, such as phenolic acids and flavonoids, which possess high antioxidant activity. However, the use of SCOBY is currently limited to serving as a starter culture for new batches of kombucha tea, necessitating innovation to enhance its other potential benefits. This study aims to evaluate the effectiveness of kombucha SCOBY gel in the healing of incised and burn wounds in mice (Mus musculus). The research methods included the preparation of kombucha tea, harvesting of SCOBY, formulation of gel, application of the gel to incised and burn wounds in mice, and observation of wound healing until closure. The results showed that kombucha SCOBY gel significantly accelerated the healing of both incised and burn wounds compared to the control group. Incised wounds fully healed by day 6, while burn wounds healed by day 7. This effectiveness is associated with the high total phenolic content (TPC) of the SCOBY gel, measured at 790.4 mg GAE/g extract, along with strong antioxidant activity of 12.42% (DPPH assay). Statistical analysis revealed a significant difference (p<0.05) in wound healing between the untreated and SCOBY gel-treated groups for both types of wounds. Therefore, kombucha SCOBY gel has potential as an effective natural topical wound-healing agent, particularly for mild to moderate wounds.   ABSTRAK (Bahasa Indonesia) SCOBY (Symbiotic Culture of Bacteria and Yeast) merupakan hasil fermentasi teh kombucha yang mengandung senyawa aktif, seperti asam fenolat dan flavonoid, yang memiliki aktivitas antioksidan tinggi. Namun penggunaan SCOBY hanya terbatas sebagai starter dalam pembuatan teh kombucha baru, sehingga diperlukan inovasi untuk meningkatkan manfaat lain dari SCOBY. Tujuan penelitian ini adalah untuk mengevaluasi efektivitas gel SCOBY kombucha dalam penyembuhan luka sayat dan luka bakar pada mencit (Mus musculus). Metode penelitian ini dimulai dari pembuatan teh kombucha, pemanenan SCOBY, pembuatan gel pengaplikasian pada luka sayat dan bakar pada mencit dan pengamatan penyembuhan luka sampai penutupan luka. Hasil penelitian menunjukkan bahwa gel SCOBY kombucha mempercepat penyembuhan luka sayat dan bakar secara signifikan dibandingkan kelompok kontrol. Luka sayat sembuh sempurna pada hari ke‑6, sedangkan luka bakar sembuh pada hari ke‑7. Efektivitas ini dikaitkan dengan tingginya kadar total fenolik (TPC) gel SCOBY, yaitu sebesar 790,4 mg GAE/g ekstrak, serta aktivitas antioksidan kuat sebesar 12,42% (uji DPPH). Hasil analisis statistik menyatakan pada luka sayat dan bakar terdapat perbedaan signifikan(p<0,05) antara kelompok tanpa perlakuan dan gel SCOBY. Dengan demikian, gel SCOBY kombucha berpotensi sebagai agen penyembuh luka topikal alami yang efektif, khususnya untuk luka ringan hingga sedang.
Identifikasi Senyawa Aktif dari Ekstrak Daun Jambu Air (Syzygium aqueum) dengan Perbandingan Beberapa Pelarut pada Metode Maserasi Eva Agustina; Funsu Andiarna; Nova Lusiana; Risa Purnamasari; Moch. Irfan Hadi
Biotropic : The Journal of Tropical Biology Vol. 2 No. 2 (2018): Biotropic, Volume 2, Nomor 2, 2018
Publisher : Program Studi Biologi, Fakultas Sains dan Teknologi, Universitas Islam Negeri Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/biotropic.2018.2.2.108-118

Abstract

Daun jambu air (Syzygium aqueum) dikenal sebagai salah satu obat tradisional, untuk menyembuhkan beberapa infeksi akibat antigen berupa bakteri. Penelitian ini bertujuan untuk mengetahui kandungan senyawa aktif yang terdapat dalam daun jambu air dengan beberapa pelarut pada proses maserasi. Metode ekstraksi yang digunakan dalam penelitian ini adalah ekstraksi dingin berupa maserasi dengan pemilihan pelarut yakni metanol (CH3OH), etil asetat dan n-heksana. Uji fitokimia yang dilakukan adalah uji saponin, flavonoid, alkaloid dan triterpenoid/steroid. Dari uji yang dilakukan diketahui sampel ekstrak daun jambu air dengan pelarut metanol positif mengandung beberapa senyawa aktif berupa flavonoid, saponin, alkaloid dan triterpenoid. Ekstrak daun jambu air dengan pelarut etil asetat dan n-heksana positif mengandung beberapa senyawa aktif berupa flavonoid, alkaloid dan triterpenoid. Pelarut yang paling bagus untuk mendapatkan banyak senyawa aktif adalah metanol. Kata kunci : Jambu air (Syzygium aqueum), maserasi, senyawa aktif
Co-Authors Abdul Muhid Agung Setyo Wibowo AGUSTINA, EVA Ahmad Sahal Aqil Abrori Arina Tri Nur Listiyaningrum Azah Zakiyatul Miskiyah Dedy Suprayogi Eko Teguh Pribadi Esti Tyastirin Estri Kusumawati Eva Agustina Eva Agustina, Eva Ferdy Pratama Fiddaroini, Achmad Farchan Gita Ika Safitri Hamim Rosyidi Ika Mustika Irssa Intan Fatiha Irul Hidayati Izza G, Moch. Rifky Jessica Anantasya Kevin Aguilera KHOIRIYAH, ROMYUN ALVY Laili Atiqoh Lia Masfiatul Khariroh Linda Prasetyaning Widayanti Mei Lina Fitri Kumalasari Mei Lina Fitri Kumalasari Mei lina Fitri Kumalasari Misbakhul Munir MISBAKHUL MUNIR Moch. Irfan Hadi Muhammad Boy Muslim Muhammad Iqbal Pratama Muhimmatul Mujtahidah Nadlir Nadlir Nadlir Nadlir, Nadlir Nafisah, Raihana Frika Naila Sayyida Ulayya Nailatin Fauziyah Nariyah, Ilut Toifatin Nova Lusiana Nugrahsari, Eilen Endah Nur Khasanah Nursa’idah Rachmaputri, Nimas Bunga Rahmania RIA SAFITRI Risa Purnamasari Risma Dewanti Rohmah, Nadia Nur Roiela Arfailasufandi Rossa Ayu Umdatus Sholichah Samas, M. Thufail Alwannabil Sarita Oktorina Shofiyya, Ainina Neihayatus Tania, Clarista Eka Vindi Fristy Kartika Wandari, Devita Ayu Winda Arifial Hikmah