Garuda - Garba Rujukan Digital

Risk Factors for Pulmonary Mycosis in Immunocompromised Patients in Surakarta, Indonesia Nugratama, Kevin Aditya; Raharjo, A. Farih; Mashuri, Yusuf Ari
Smart Medical Journal Vol 7, No 1 (2024): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v7i1.78386

Introduction: Recent evidence shows that there is an increase in the incidence of pulmonary mycosis globally. In clinical settings, pulmonary mycosis is commonly misdiagnosed as pulmonary tuberculosis (PTB). Identifying risk factors can ease the diagnosis of pulmonary mycosis. This study aimed to determine the risk factors for pulmonary mycosis in immunocompromised patients in Surakarta.Methods: This was an analytic observational study with a retrospective cohort study method. This study used purposive sampling technique on 218 medical records of immunocompromised patients during January 2019–September 2022 at a referral hospital in Surakarta. The correlation of sociodemographic, health status, health behavior, history of diseases, medications, and transplantations with the incidence of pulmonary mycosis was analyzed using Chi-Square test or Fisher’s exact test as its alternative.Results: There was a significant correlation between educational level (p=0.018), nutritional status (p=0.001), smoking habit (p=0.000), history of corticosteroid use (p=0.031), history of antibiotic use (p=0.006), history of chemotherapy (p=0.003), history of PTB (p=0.047), and history of chronic obstructive pulmonary disease (COPD) (p=0.001) with the incidence of pulmonary mycosis. Meanwhile, there was no significant correlation between occupation (p=0.057), neutrophil level (p=1.000), history of human immunodeficiency virus (HIV) infection (p=1.000), history of diabetes mellitus (DM) (p=0.070), and history of organ transplantation (p=1.000) with the incidence of pulmonary mycosis.Conclusion: Low educational level, malnutrition, smoking habit, history of pulmonary diseases, and medications are the risk factors for pulmonary mycosis in immunocompromised patients in Surakarta. It is important to identify these risk factors when examining patients with respiratory disorder symptoms.

The Relationship between Sleep Quality, Cyberbullying, and Internet Addiction in Adolescents Paramita Septianawati; Irma Finurina Mustikawati; Inggar Ratna Kusuma; Tisna Sendy Pratama
Smart Medical Journal Vol 8, No 2 (2025): August
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v8i2.97309

Background: Teenagers use the internet for their daily needs such as attending online classes, watching entertainment (such as YouTube or playing games) or even playing social media. The purpose of this study was to determine the relationship between cyberbullying incidents and sleep quality with internet addiction in adolescents.Research Methods: This study used an observational analytical method using the PSQI, KDAI, and cyberbullying questionnaires. 276 adolescent respondents who were willing to fill out the questionnaire distributed via G-form were obtained. This study was analyzed with SPSS 26.0.Results :The univariate results showed that 75 (27.2%) adolescents were addicted to the internet, 82 (29.7%) adolescents had been victims/perpetrators of cyberbullying, respondents experienced overall sleep quality, 90 students (32.6%) had good sleep quality and 186 students (67.4%) had poor sleep quality. The results of the bivariate analysis of this study found a significant relationship between internet-addicted teenagers and cyberbullying perpetrators (p = 0.000). A significant relationship was found between cyberbullying victims and internet addiction (p = 0.028). There was a significant relationship between subjective sleep quality (p = 0.000), sleep latency (p = 0.022), and sleep disturbance (p = 0.032) with internet addiction (p <0.05). The results of the Chi-Square statistical test obtained a value of 0.031, there was also a significant relationship between overall sleep quality and internet addiction. Using logistic regression, it can be seen that the independent variables that have a sig. <0.05 are the cyberbullying perpetrator variables and subjective sleep quality, so it can be said that both independent variables have a significant effect on internet addiction.Conclusion: Significant relationship between subjective sleep quality and cyberbullying perpetrators on teenagers who tend to be addicted to the internet.

Optimization of Cream Ethanol Extract of Duku Leaves (Lansium domesticum Corr.) as Antibacterial Against Staphylococcus aureus Using the Simplex Lattice Design Method Saryanti, Dwi; Prameswari, Sekar Mayang
Smart Medical Journal Vol 6, No 3 (2023): December
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v6i3.74030

Introduction: The secondary metabolites flavonoids and triterpenoids in duku leaves have antimicrobial properties. Cream have some drawbacks, including fragility to erratic stirring, brittleness when dried up, and poor storage stability. Triethanolamine reacts with stearic acid will form triethanolamine stearate which can increase stability of the cream. This research aimed to find the ideal ratio of stearic acid to triethanolamine for making an antibacterial composition.Methods: Optimization of the cream is carried out by Simplex Lattice Design method, made 8 run with the smallest proportion of stearic acid 15g and the highest 17g, and the smallest proportion of triethanolamine 2g and the highest 4g. Responses used in Simplex Lattice Design, namely pH, viscosity, adhesion, and spreadability. T-test was used to verification of the optimal formula and ANOVA was used to analysis of antibacterial data.Results: The optimal formula was 17 grams of stearic acid and 2 grams of triethanolamine make the optimal cream. The test results show that there is no significant difference between the optimal formula and the predictions in the Simplex Lattice Design software, with a pH of 6.33±0.033, a viscosity of 179.67±0.333, an adhesion of 1.377±0.038, and a spreadability of 5.133±0.044. The best formula has moderate antibacterial activity (6.62±0.007 mm inhibition zone) against Staphylococcus aureus.Conclusion: The optimal formula has good physical properties and is efficacious as an antibacterial.

The Effect of Citronella oil Concentration on Physicochemical Properties of Laponite Hydrogel and Antimicrobial Activity Test to Streptococcus aureus ATCC 25923 and Candida albicans ATCC 14053 Ermawati, Dian Eka; Putriana, Susanti; Susanto, Nindita Claurisa Amaris
Smart Medical Journal Vol 7, No 2 (2024): August
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v7i2.92213

Introduction: The Citronella plant produces 78 -85% citral oil. This oil has antimicrobial activity. The oil was developed as an antimicrobial topical and incorporated into laponite hydrogel for optimal use. Laponite hydrogel has a cooling sensation and is compatible with polar and non-polar active substances. This study aims to evaluate the effect of citronella oil concentration on physicochemical properties and examine its antimicrobial activity.Methods: The Citronella plant was distilled using the steam distillation method and analyzed using the GC-MS. The laponite hydrogel was prepared with three concentrations: 6%, 8%, and 10%. Physicochemical properties included pH value, viscosity, stickiness, spreadability, and organoleptics, and the chosen formula was tested for antimicrobial activity. The research data were compared with relevant literature, and ANOVA statistics were analyzed with a confidence level of 95%.Results: Based on the research results, increasing the concentration of citronella oil caused the laponite hydrogel to become increasingly cloudy, viscosity, and sickness but decreased the pH and spreadability. Citronella oil concentration of 8% is the chosen formula that fulfills the best hydrogel preparation with evaluation results of pH value of 7.24 ± 0.064, spreadability of 5.68 ± 0.320 cm, thickness of 1.25 ± 0.012 seconds, and viscosity of 23596.3 ± 227.55 mPa. s. The citronella oil hydrogel has antibacterial and antifungal properties and moderate strong inhibitory.Conclution: As a delivery system for citronella oil, Laponite can be developed as a pharmaceutical preparation to treat mouth ulcers as an alternative synthetic product with good antimicrobial potential.

Does Location Matter? Impact of Tumor Location (Peripheral vs Central) on Surgical Outcomes of Segmentectomy in Early Stage NSCLC: A Meta-Analysis Mada Ilham Bawono; Mohammad Rizky Ariesto; Belinda Mufidah; Mada Dwi Hari
Smart Medical Journal Vol 9, No 1 (2026): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v9i1.115488

Introduction: Recent studies recommend segmentectomy for early-stage peripheral NSCLC due to better lung parenchyma preservation; however, its role in early-stage central NSCLC remains debated. This study aims to analyze the impact of tumor location (peripheral vs central) on segmentectomy outcomes in early-stage NSCLC.Methods: Only studies comparing segmentectomy outcomes by tumor location (peripheral vs central) in early-stage (T1a–cN0M0) NSCLC will be included. Studies involving lobectomy, wedge resection, or more advanced stages will be excluded. We registered the study protocol on PROSPERO (CRD420251127645). Article searches will be conducted in PubMed, Scopus, and Web of Science. All databases were last searched on 16 August 2025. Risk of bias will be assessed using the Newcastle–Ottawa Scale. Data will be analyzed with RevMan 5.4 and presented as forest plots.Result: Five cohort studies were included, comprising a total 2,134 participants (1,499 peripheral and 635 central tumours) were included. The meta-analysis findings indicated that there were no significant differences between peripheral and central tumor locations regarding 5-year overall survival, recurrence-free survival, recurrence patterns, or intraoperative blood loss. However, segmentectomy performed for peripheral tumors resulted in a significantly shorter operative duration compared with procedures for central tumors (SMD −0.20; 95% CI −0.30 to −0.10; p < 0.0001).Conclusion: This study has limitations due to the small sample size and study design, which affect its generalizability. Nevertheless, the analysis results indicate that segmentectomy is also a choice of treatment for early-stage central NSCLC.

Correlation Between Sleep Quality and Acne Vulgaris Incidents Among Medical Students in Surabaya Wahyuni Dyah Parmasari; Tansatrisna Vony Rei Siswanto; Suhartati Suhartati
Smart Medical Journal Vol 8, No 2 (2025): August
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v8i2.102883

Introduction: The symptoms of acne vulgaris, a chronic inflammatory condition of the sebaceous glands, include comedones, papules, pustules, and nodules. Eighty to one hundred percent of people have acne vulgaris. Adolescent boys aged 16-19 and females aged 14-17 had the highest incidence. It is projected that sleeping late at night would enhance the activity of androgenic hormones, which regulate the mechanism of sebum production in the skin. This will make the skin greasier, making it more prone to acne than normal, dry skin. Reviewing the association between acne vulgaris incidence and sleep quality among 17-23-year-old students at Wijaya Kusuma University’s Faculty of Medicine in Surabaya was the aim of the Study.Methods: Data from 196 respondents were gathered for this study using a cross-sectional survey method. All sample is a females. When analyzing data, SPSS Statistics is used to process the Chi-Square Test.Results: The study’s findings indicate that 83 respondents (58,5%) had mild acne vulgaris, 52 respondents (36,6%) had moderate acne vulgaris, and 7 respondents (4,9%) had severe acne vulgaris. Of the respondents, the majority (116 respondents, 81,7%) did not have enough sleep or had poor quality of sleep. While 26 respondents (18,3%) had a good quality of sleep. The Chi-Square test findings indicated a correlation between the incidence of acne vulgaris and sleep quality, with a value of 0.04<0.05.Conclusion: The strain of studying and a full lecture schedule can make it difficult to manage their time effectively, leading to a lack of sleep patterns and quality. Hormones are impacted, and a contributing element is an unclean face.

The Relationship Between Stress and Eating Habits and the Occurence of GERD in Medical Students Puspitasari, Aldayanti; Sukmagautama, Coana; Sari, Amelya Augusthina Ayu; Hermawati, Berty Denny
Smart Medical Journal Vol 7, No 2 (2024): August
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v7i2.85024

Introduction: Gastro Esophageal Reflux Disease (GERD)is a disorder when food that has entered the stomach, goes back up into the esophagus or reflux, from several literature that has been read, in Indonesia many people experience this due to excessive stress, researchers develop existing research using the object and focus of research different. Research was conducted to determine the relationship between stress and eating patterns consisting of regular eating, consumption of spicy food, and consumption of fatty foods in UNS medical faculty students.Method: The research carried out was quantitative research with an observational analytical design and a cross-sectional approach. The research was conducted at the Faculty of Medicine, Universitas Sebelas Maret with a sample of 102 students, namely students from the Faculty of Medicine class 2020-2022. In collecting data, researchers used the GERD-Q questionnaire, the meal pattern questionnaire, FFQ and PSS. Followed by analyzing the data through editing, coding, scoring, tabulating, univariate, bivariate and multivariate analysis.Results: (1) There is a significant relationship between stressful conditions and the incidence of Gastroedophageal Reflux Disease (GERD) in UNS medical students; (2) there is a significant relationship between eating habits consisting of regular eating, consuming spicy food, consuming oily food and the incidence of Gastroedophageal Reflux Disease (GERD) in UNS medical students; (3) Based on a multivariate test, it was found that the most significant independent variable in the incidence of Gastroedophageal Reflux Disease (GERD) in UNS medical students was the habit of consuming oily/fatty foods which was 2 times faster in triggering the occurrence of GERD.Conclusion: From the discussion presented, it can be concluded that there is a significant relationship between stress and eating habits and the occurrence of GERD.

Correlation Study between Population Density and Tuberculosis Incidence at Selogiri Community Health Center Area in 2023 Heni Hastuti; Endang Sulaeman Sutisna; Anak Agung Alit Kirti Estuti Narendra Putri; Ninik Hartini
Smart Medical Journal Vol 8, No 3 (2025): December
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v8i3.107458

Introduction: Tuberculosis (TB) is an infectious disease that a public health issue both globally and nationally, with high incidence rates including Indonesia. Factors such as drug resistance, population mobility, and decreased vaccination coverage can worsen the situation. One of the influencing factors is population density, transmission through airborne droplets due to the closer proximity of individuals and poor air circulation. In the Selogiri Community Health Center area, the number of TB cases shows a concerning trend, making it important to investigate the relationship between population density and the incidence of TB.Methods: This cross-sectional ecological correlation study was conducted in the Selogiri Community Health Center area covering a total population of 46,964 people. Secondary data were obtained from TB case reports and demographic data. The analysis used the Pearson correlation test after confirming the assumptions of linearity and normality.Results: The study shows a positive and significant association between population density and the number of TB cases in the Selogiri Community Health Center area in 2023, with a correlation value of r = 0.825 and p = 0.002. Villages with higher population density, such as Kaliancar and Jendi, recorded a higher number of TB cases compared to villages with lower density. The findings indicate that higher population density is strongly associated with an increased number of TB cases, highlighting the need for special attention in disease prevention and control strategies in densely populated areas.Conclusion: There is a significant relationship between population density and TB cases in the Selogiri Community Health Center area in 2023; the higher the density, the higher the TB cases.

Current Progress in Developing Plant Extract-Based Hepatoprotective Drugs to Prevent Drug-Induced Liver Injury During Tuberculosis Treatment: A Literature Review Fenny Fenny; Joan Joan; Ardo Sanjaya; Julia Windi Gunadi
Smart Medical Journal Vol 8, No 1 (2025): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v8i1.91713

Introduction: Anti-tuberculosis treatment (ATT) can cause drug-induced liver injury. This complication leads to disruption of tuberculosis treatment. Therefore, plant extract-based is useful in a way to prevent drug-induced liver injury due to ATT. Methods: This review source came from PubMed and Google Scholar. We found 59 articles with the keywords “drug-induced liver injury” AND “hepatotoxicity” in the range 2014-2024. We selected 12 articles to be reviewed in this article. Result: Plant extract-based in this article has several mechanisms to prevent drug-induced liver injury due to ATT. All of them contain high antioxidants. Silymarin works by blocking the effects of the enzymes catalase and glutathione peroxidase, as well as suppressing the action of lipid peroxidase which causes liver damage. Jujube, Lasianthera africana, and Telfairia occidentalis can neutralize free radicals. Trapa natans and Bacopa monnieri work from the glutathione (GSH) pathway. Bacoside and Tamarix gallica mechanisms to prevent liver injury are still unknown. Most of the herbs can decrease levels of AST, ALT, and ALP as biomarkers of liver injury significantly. Conclusion: Many plant extracts have the potential to prevent the incidence of drug-induced liver injury caused by ATT both in animal models and clinical trials. However, adequate dosing and sample size are required to make sure that the effects are significant.

Low Birth Weight as Predictor of Underweight and Stunting Among Female Students Aged 6-9 Years: an Observational Study in Surakarta Shabrina, Amalina; Ayusari, Amelya Augusthina; Dewi, Yulia Lanti Retno; Wiboworini, Budiyanti; Sudarsono, Joko; Handayani, Sutartinah Sri; Rahayu, Dwi
Smart Medical Journal Vol 7, No 1 (2024): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v7i1.79718

Introduction: Undernutrition remains a leading cause of premature mortality among children in developing countries. Previous studies discussed that the risk of undernutrition elevated with child’s age, stressing the need to address undernutrition in older children. Maternal factors also caused undernutrition through intergenerational transmission. However, data related to nutritional status of female children age >5 years in Indonesia are lacking. This study aimed to elucidate determinants associated with nutritional status among primary school girls in Surakarta.Methods: This was an observational, cross-sectional study. A total of 61 female students aged 6-9 years from Nur Hidayah Primary School Surakarta participated in this study. Data were collected through online questionnaire filled by parents who were directed to follow the procedures of anthropometric measurement at home. Z-score was calculated using WHO AnthroPlus software. Nutritional status of children was measured in weight-for-age and height-for-age. Statistical analyses were performed using Spearman’s correlation and backward linear regression. Variables with p<0.05 from the final model were considered as the determinants.Results: Among study participants, 4.9% were underweight and 9.9% were stunted. Our study found one common determinant of nutritional status by weight-for-age and height-for-age, namely birth weight (p=0.027 and p=0.011 respectively). Maternal height was, in particular, associated with nutritional status by height-for-age (p=0.001).Conclusion: Birth weight was significantly associated with nutritional status by weight-for-age and height-for-age, while maternal height was significantly correlated with only nutritional status by height-for-age. Nutrition programs for female students such as school lunch and multivitamin supplementation could be implemented to prevent the intergenerational effects of stunting and underweight.

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Nanang Wiyono

Contact Email
smjfkuns@gmail.com

Phone
-

Journal Mail Official
smjfkuns@gmail.com

Editorial Address
-

Location
Kota surakarta,

Jawa tengah

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Nanang Wiyono

Contact Email smjfkuns@gmail.com

Phone -

Journal Mail Official smjfkuns@gmail.com

Editorial Address -

Location Kota surakarta, Jawa tengah INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Nanang Wiyono

Contact Email
smjfkuns@gmail.com

Phone
-

Journal Mail Official
smjfkuns@gmail.com

Editorial Address
-

Location
Kota surakarta,

Jawa tengah

INDONESIA