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Buletin Farmatera
Published by Universitas Muhammadiyah Sumatera Utara
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 244 Documents
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Comparison of Covid-19 Vaccine Hesitancy in Healthy Adult Populations and Patients with Anxiety Disorders Annisa Annisa; Nanda Sari Nuralita; Yulia Afrina Nasution
Buletin Farmatera Vol 7, No 3 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i3.11949

Abstract

Vaccine hesitancy is one of the world's health problems that poses a threat to global health. This condition is influenced by various things, one of which is a mental condition. Willingness to receive vaccines, especially during the Covid-19 pandemic is very important. This study is a cross-sectional study involving 73 patients with anxiety disorders and 63 healthy adults. About 80% of the subjects were willing to be vaccinated. Based on the level of confidence in the vaccine, 90% of the subjects (66.20%) believed in the usefulness of the vaccine. A total of 39 people (28.7%) lacked confidence in vaccines. There were 28 subjects who refused vaccination, of which 26 were anxiety sufferers. The most common reasons for reluctance to vaccinate are fear of side effects (29.4%) and fear of injections (13.2%). In this study, 80% of the subjects had been vaccinated, according to the government's vaccination target. However, to maintain the success of long-term vaccination programs in populations with certain diseases, a more specific approach is needed.
Gambaran Penerima Transfusi Darah Pada Ruang Rawat Pediatrik di Rumah Sakit Umum Cut Meutia (RSCM) Aceh Utara 2019 2020 Teuku Ilhami Surya Akbar; Syifa Chairunnisa; Vera Novalia
Buletin Farmatera Vol 7, No 3 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i3.11575

Abstract

Abstract: Giving blood or blood components from a healthy person (donor) to another person is known as blood transfusion. A blood transfusion is intended to save a person's life. The number of blood donors has increased in the last decade, but it is still insufficient to meet the demand for blood. According to WHO guidelines, at least 2% of the total population requires blood, but the use of blood in hospitals is currently very limited. Adults receive blood transfusions more frequently than children and neonates. In adults, it is most commonly used in internal medicine, and in children, it is most commonly used in cases of thalassemia. The purpose of this study is to identify the characteristics of patients receiving transfusions in the pediatric ward at Cut Meutia General Hospital in North Aceh in 2019-2020. The descriptive method was used in the research. Total sampling was used in this study, thedata taken from the patient's medical records at the North Aceh Hospital in 2019-2020 obtaining 89 samples. The study's results for transfusion recipients were frequently found in male sex (55.1%), at 5 years - 11 years (38.2%), blood type O (51.7%) frequentlywith rhesus positive (98.9%). Thalassemia patients received the majority of blood transfusions (50.0%), and blood components were almost always PRC (98.9%). The conclusions in this study were male blood transfusion recipients, aged 5-11 years, blood type O rhesus positive, diagnosis of thalassemia and blood components used by PRC.
Intra Articular Injection of Mesenchymal Stem Cells in Osteoarthritis of the Knee Joint: A Systematic Review Ilham Hariaji
Buletin Farmatera Vol 7, No 3 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i3.11981

Abstract

Abstract: Treatment of osteoarthritis in the knee joint is carried out by sharing efforts. In addition to pharmacological therapy, it is also carried out therapy with the method of intra-articular injection of mesenchymal stem cells directly into the knee joint. This systematic study aims to find out the extent to which this method has been studied as well as the benefits of intra-articular knee joint by means of mesenchymal stem cells. This study was conducted as a systematic study by searching journal literature through the Google Scholar application with the keyword intra articular injection mesenchymal stem cells on knee osteoarthritis in the last 5 years, using a prism diagram classification system in article selection. The results of the selection found 41 articles that were included in the inclusion criteria. The results of the study found that there have been many studies of intra-articular injection therapy of mesenchymal stem cells from various sources. Research was carried out both pre-clinical and clinical, and assessment methods were carried out with various methods to see the results of the therapy given, and 90% showed the results of structural, functional, and clinical improvement of the knee joint. From the results of these studies, it is concluded that there have been many studies conducted and most have shown that this method provides benefits.
The Safety Evaluation of Some Plants of the Zingibereceae Family Doni Anshar Nuari; Asman Sadino; Suci Hilwa Ainaya
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.11478

Abstract

Overview of Ivabradine Drug: Use and History Melviana Lubis
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.12751

Abstract

Despite the significant advances in management and prevention, heart failure still cause high mortality and morbidity. Ivabradine is one example of a new drug used in the treatment of heart failure with decreased ejection fraction. Ivabradine history and use is interesting that it can improve our understanding to cardiovascular pathophysiology. There may also be extended indications for Ivabradine use in the future.
Analysis of Breast Care Factors for Increasing Breast Milk Production In Pagar Merbau Public Health Community Center, Medan Zaim Anshari
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.5522

Abstract

Breastfeeding is the obligation of a mother to give milk to her baby after childbirth (post-partum). To provide the right quantity and quality of breast milk that requires a formal agreement, such as maintaining and caring for breasts. Breast care should start from the time of pregnancy during childbirth (puerperium). Several factors that need to consider in breast care are providing breast massage, maintaining breast hygiene, using a bra as a breast protector, and consuming nutrition. This study is a quasi-experimental study that aims to determine whether breast care can increase milk production in post-partum mothers. The results showed that offering massage to the breasts, maintaining breast hygiene, and consuming nutrition affected the production of breast milk in post-partum mothers. The use of a bra in post-partum mothers does not have a significant effect on increasing milk production in post-partum mothers.
The Correlation of Body Mass Index with Visceral and Subcutaneous Adipose Tissue Volume in Patients that Performed Abdominal CT scan at RSUP H. Adam Malik Medan Duma Ratna Sari Nasution; Netty Delvrita Lubis; Naomi Niari Dalimunthe
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.12656

Abstract

Visceral and subcutaneous adipose tissue (VAT and SAT), and excess body mass index (BMI) act as cardiometabolic risk factors. BMI only describes the ratio of body weight to height in general. Abdominal CT scan is the gold standard in the examination of VAT and SAT volumes. The purpose of this study is to analyze the correlation between BMI with VAT and SAT in patients that performed CT scans of the abdomen. A total of 60 patients who underwent CT scans of the abdominal region at the Radiology Department of the RSUP H. Adam Malik Medan from July to August 2022 participated in this cross-sectional study. The BMI was calculated from measurement and volume of VAT and SAT were obtained from CT scans of the abdominal region at the fourth lumbal level, using 3D smart segmentation. Among of samples was 51.7% male. Average of age and BMI are 49.3 12.18 years and 25.58 kg/m2. Average of VAT and SAT volume value are 678.13 436.09 cm3 and 1708.76 1068.99 cm3. There is a moderate positive correlation between BMI and VAT (r=0.687) and BMI and SAT (r=0.669) with p0.001.
Yield Analysis and Phytochemical Screening of Ethanol Extract of Phaleria macrocarpa Leaves Ira Cinta Lestari; Dharma Lindarto; Syafruddin Ilyas; Tri Widyawati; Suryani Eka Mustika
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.11724

Abstract

Phaleria macrocarpa leaves have the potential to be used as raw materials for medicines derived from natural ingredients, but research is needed to determine the content and efficacy of these plants. This study aims to analyze the yield and screening of the content of phytochemical compounds in the ethanolic extract of the Phaleria macrocarpa leaves. This research is a descriptive study. Extract yield analysis was performed by calculating the weight ratio of the extract divided by the simplicia multiplied by one hundred percent. Screening for the phytochemical content was carried out for compounds belonging to the class of flavonoids, saponins, tannins, alkaloids, steroids, and triterpenoids. The results of the calculation of the yield of the extract obtained were 14.58% and the results of the phytochemical test showed that the extract contained flavonoids, alkaloids, tannins, glycosides, saponins, and steroids.
Malnutrition Screening Is Better Than Body Mass Index for Predicting COVID-19 Severity Fitri Nur Malini Siregar; Asri Ludin Tambunan; Eka Febriyanti
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.11619

Abstract

Abstract: Several factors can influence the severity of COVID-19, including nutritional status and malnutrition conditions. This study compares malnutrition screening methods with body mass index to find better predictors of COVID-19 severity. This study is a cross-sectional analysis of medical records from all adult COVID-19 patients (total sampling) treated at Amri Tambunan Deli Serdang Hospital. The World Health Organization criteria were used to determine the severity of COVID-19. A Global Subjective Assessment (SGA) questionnaire was used to screen for malnutrition, while anthropometric measurements (Kg/m2) were used to calculate the Body Mass Index (BMI). The Chi-Square Test was used for statistical analysis. This study included 508 COVID-19 hospitalisation patients, the majority of whom were women (55.5%), aged 18-29 years (25%) and had moderate severity (89.6%). The seriousness of COVID-19 was associated with malnutrition conditions as measured by the SGA questionnaire (p0.001), with patients with moderate to severe malnutrition being 3.4 times more likely to develop robust and critical COVID-19 (95% CI 1.6 - 7.0). There is no significant relationship between Body Mass Index and the severity of COVID-19 (p0.05). Malnutrition screening with SGA is more accurate than BMI in predicting the severity of COVID-19. Keywords:   IMT, a predictor of COVID-19 severity degree, malnutrition screening 
Microscopic Features of Central Caseous Necrosis in Tuberculosis Lymphadenitis Patients: The Relationship with Lymphocyte Density Rafa Nabila Haifa; Humairah Medina Liza Lubis
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.12282

Abstract

Tuberculosis lymphadenitis (TBLN) is the most common extra pulmonary TB (EPTB) case in the world with a range of 30-40% of all EPTB cases. When the body's immune system cannot kill the pathogen, the body will try to contain the pathogen (granuloma). The outer portion of the granuloma becomes calcified and the cells in the center undergo necrosis. The formation of central necrosis is associated with the emergence of cellular hypersensitivity with the features of local accumulation of macrophages and lymphocytes. The current study aimed to determine the relationship between the microscopic features of central caseous necrosis with lymphocyte density in patients with tuberculous lymphadenitis. Thirty histopathological slides of TBLN patients were observed under a microscope to see the features of central caseous necrosis and assess the lymphocyte density with the results assessed based on the cutoff point of the median of all lymphocyte mean values. Based on the microscopic examination, 25 samples of central caseous necrosis were found and the other 5 samples were not found to have caseous necrosis. Twenty-six patients had low lymphocyte density, and 4 patients had high lymphocyte density. The results of the Fisher Exact test obtained p = 0.009. There is a significant relationship between the features of central caseous necrosis and lymphocyte density in patients with TBLN.

Page 15 of 25 | Total Record : 244

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