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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
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Articles 12 Documents
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Search results for , issue "Vol 5, No 1 (2020)" : 12 Documents clear
Association between Resistin and High Sensitive Troponin I in St Elevation Myocardial Infarction and Systolic Heart Failure Wasyanto, Trisulo; Febrilia, Laurent
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Nearly half of all patients with acute myocardial infarction (AMI) have left ventri­cular systolic dysfunction and one-third have symptoms of heart failure (HF). In patients with AMI the resistin level correlated inversely with left ventricular ejection fraction (LVEF). Increased levels of high sensitive (hs) troponin I are associated with poorer prog­nosis. This study aimed to deter­mine the association between levels of resistin and hs troponin I in ST elevation myocardial infarc­tion (STEMI) patients with systolic HF.Subjects and Method: This was a cross-sectional study was conducted at Dr. Moewardi Gene­ral Hospital, Surakarta, from April 1 to May 31, 2018. A sample of 32 patients who admitted which diagnosed with STEMI was selected for this study. They were divided into two group according to result of LVEF mea­sure­ment, LVEF < 40% and LVEF ≥ 40%. Blood examination and transthoracic echo-car­diography were performed to all patients. Cor­re­lation test using partial and multiple cor­relation test. To different 2 mean using Mann Whitney test.Results: Mean of patient age was 59.5 years old. Resistin decreased LVEF (r= -0.41; p= 0.009), and it was statistically significant. Hs troponin I decreased LVEF (r= -0.25; p= 0.081), but it was marginally significant. Resis-tin level and hs troponin I increased LVEF (r= 0.47; p= 0.025), and it statistically significant.Conclusion: There was an association between resistin and hs troponin I level together in STEMI patients with systolic HF. There was an association of resistin levels in STEM I patients with systolic HF. There was no association of hs troponin I levels in STEMI patients with systolic HF.Keywords: Resistin, hs troponin I, STEMI, systolic heart failure.Correspondence: Trisulo Wasyanto. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sebelas Maret/ Dr. Moewardi Hos-pital. Jl. Kol. Sutarto 132, Surakarta 57126, Central Java, Indonesia. Email: trisulo.wasyanto@gmail.com.Indonesian Journal of Medicine (2020), 5(1): 1-9https://doi.org/10.26911/theijmed.2020.05.01.01
Comparative Study of Cross and Lateral Fixations on Supracondylar Humerus Fracture among Children Irianto, Komang Agung; Martanto, Tri Wahyu; Brahmana, Febrian; PK, Laskar
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Management of Gartland type III supracondylar humerus fractures is conduc­ted by open and closed repositioning. An ade­quate re­p­o­sition and a stable and accurate fixation are des­perately needed to prevent fixation failure, defor­mi­ty, and complication. The study aims to com­pa­re the clinical and radiological results bet­ween crossed and lateral fixation techniques.Subjects and Method: The study was a retro­s­pective study toward Gartland type III SCHF children in Dr. Soetomo Hospital, Surabaya, Indonesia from 2013–2016. The dependent vari­able is Supracondylar hu­me­rus fracture. Independent variables were the type of fixation option, clini­cal functional test, degrees of satisfactory, and radiology evalua­tion. The radiology para­me­ter used was Skaggs criteria. An observation was conducted for the occurrence of complications in the form of infection and peripheral nerve injury. All data were analyzed using Kolmogorov Smirnov and Fischer exact test.Results: The study discovered 28 patients consisted of 20 males and 8 females with an age range from 3 – 13 years old with an average age in crossed fixation group was 7.6 years and in lateral fi­x­ation was 4.7 years. The injury sides were 46.4% right elbow and 53.5 % left elbow. Among the cros­sed fixation group, there were 54.5 % left elbow and 45.5 % right elbow. Among lateral fix­a­tion group, there were 50% left side and 50% right side. There was no significant difference in cli­nical fun­ctions, radiology as well as com­pli­ca­tion in the form of infection and peripheral ner­ves injury.Conclusion: There is no difference of functional clinical, radiology result as well as post-surgery com­plication in the form of infection and peri­phe­ral nerves injury between crossed fixation tech­nique and lateral fixation technique.Correspondence: Komang Agung Irianto. Department of Ortho­pe­dics and Traumatology, Faculty of Medicine, Universitas Airlangga/ Dr. Soetomo Hospital, Sura­ba­ya. Email: komang168@yahoo.com. Mo­bile­: +6281133608­0.Indonesian Journal of Medicine (2020), 05(01): 31-37https://doi.org/10.26911/theijmed.2020.05.01.05
Bilateral Hepatic Subcapsular Biloma: A Rare Case Report Pramana, Triyanta Yuli; Widiastuti, Widiastuti
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Biloma is loculated collection of bile that may develop due to iatrogenic causes, trauma­tically or spontaneously with biliary tree disruption. Hepatic bilateral subcapsular bi­loma is a rare complication of laparoscopic cho­lecys­­tec­tomy and an even more scarce when it occurs spontaneously.Case Presentation: A 65 years old man came to our hospital with abdominal pain and en-larged abdomen. Six weeks earlier he under­went laparoscopic cholecys­tectomy in a private hospi­tal, because of stone in the gall bladder and cho­lecys­titis. The physical examina­tion obtained no icteric and distended abdomen with pain on palpation. Laboratory findings were within nor­mal limit with negative viral infection markers. Abdominal ultrasonography revealed chronic liver disease with giant liver cyst and ascites. Contrast abdominal multi-slice computed mono­graphy (MSCT) demonstrated bila­teral hepatic sub­capsular biloma. Laparatomy and drainage were then performed and he was discharged from the hospital several days later in good condition.Discussion: Biloma was first introduced by Gould and Patel in 1979. The incidence of past laparoscopic cholecystectomy biloma is very low, between 0.6% and 1.5%. Early accurate diagnosis is very important to determine the proper mana­gement. In our case, the biloma was found by using USG and MSCT.  Usually it presents with right upper quadrant or epi­gastric pain, abdo­minal distention, fever and leukocytosis, but our patient did not have either fever or leukocytosis. Actua­lly the first treatment choice is percuta­neous catheter drai­nage but in our case laparo­tomy drainage was performed because of sub­capsular, biloma in both right and left hepatic lobes.Conclusion: Bilateral hepatic subcapsular bilo­ma is a rare case. One of its diagnostic tools is MSCT. Biloma drainage is the first choice of treatment.Keywords: Biloma, post laparoscopic cho­lecys­­­tec­tomy, drainageCorrespondence: Triyanta Yuli Pramana. Department of Gastro­enterology and Hepatology Division, Dr. Moe­wardi Hospital/ Faculty of Medi­cine, Univer­si­tas Sebelas Maret. Email: typra­ma­na@­gma­il­.comIndonesian Journal of Medicine (2020), 05(01): 52-56https://doi.org/10.26911/theijmed.2020.05.01.08
The Determination of Haemostasis Value in Relation to Potential Blood Leaf Leaves Filtrate (Excoecaria cochinchinensis L) as the External Medicine for Skin Wound of White Rat (Rattus norvegicus) Zaetun, Siti; Srigede, Lalu
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Plants are currently used as medicine, i.e. medicinal plants. Medicinal plants con­sist of many chemical compounds, especially bioactive substances. One of them is Sambang Darah (Excoecaria cochinchinensis). Sambang Darah have so many benefits which usually applied in vulnus combutio. This study aimed to determine value of haemostasis after applied Sambang Darah leaves in white rat skins (Rattus norvegicus).Subjects and Method: This was a true experimental study with post test only control group de­sign. This study conducted at Mata-ram University, West Nusa Tenggara, Indo-nesia, from April to October 2017. A total sam-ple of 16 whi­te rats was selected for this study. The dependent variable in this study was the value of haemostasis and the independent vari-able was filtrate of Sambang Darah leaves. The data were analyzed using Man Whitney test.Results: The average level of bleeding time was 3.76 minutes for the control group and 2.58 mi­nu­tes for test group. The average level of clotting time were 2.20 minutes for control group and 1.36 mi­nutes test group. The number of platelet was 277,000/uL for the control group and 221,000/uL for test group. APTT level was25.06 second for the control group and there was no clot in test gro­up. PT level was 13.95 second for the control group and there was no clot in test group. TT levels was 18.2 second for the control group and there was no clot in test group. And the last, D Dimer level was 0.1 mg/l for the control group and there was no clot in test group. The statistical analysis sho­wed p ≤0.001.Conclusion: Filtrat of sambang darah leaves can be applied as medicine for external wounds but it can not be applied in koagulasi test.Keywords: Haemostasis value, blood leaf filtrate (Excoecaria cochinchinensis L)Correspondence: Siti Zaetun.Program Study of Health Analyst, School of Health Polytechnic, Ministry of Health, Mataram. Jl. Prabu Rangkasari, Dasan Cermen, Sandubaya, Mataram, West Nusa Tenggara. Email: miraigan@yahoo.co.id. Mo-bile: 081803630063.Indonesian Journal of Medicine (2020), 5(1): 10-16https://doi.org/10.26911/theijmed.2020.05.01.02
The Difference of Endometrial Leptin Expression in Woman with Polycystic Ovarian Syndrome (PCOS) Compared to Normal Besar, Dwi Sakti Berlian; Budihastuti, Uki Retno; Sulistyowati, Sri; Melinawati, Eriana
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Decreased endometrial recep­ti­vity is suspected to be one of the factors causing in­fertility in women with Polycystic Ovary Syn­dro­me (PCOS). Endometrial abnormalities in PC­OS­ due to impaired balance include estrogen, pro­­­­gesterone, growth factors, cytokines and cell at­tach­­­ment modulators including leptin. This study aims to determine the expression of leptin in the endometrium which is suspected to be more common in PCOS patients and related factors.Subjects and Method: A retrospective-case control study was conducted at Dr. Moe­wardi general hospital, Surakarta. A total of 60 women were involved; 30 infertile women with PCOS based on Rotterdam criteria (if found two of the three symptoms, including hyperandrogenism, ovu­la­tion dysfunction and/or polycystic ovaries from ultrasonography) and 30 normal women as con­trol group. Demographic data such as age, family history of PCOS, menarche, BMI, occupation, and edu­cation were recorded. Leptin expression was acquired from endometrium biopsy with IHC examination on day 19-24 of the menstrual cycle; under the condition that inclusion and exclusion cri­teria are fulfilled. The statistical analysis was per­formed using the Mann-Whitney test.Results: Mean of leptin expression was found significantly higher in PCOS group (Mean= 59.16; SD= 49.34) compared to control group (Mean= 6.00; SD= 22.98, with p= 0.001. PCOS (b= 0.42; 95% CI= 0.10 to 0.73; p= 0.010) and obesity (b= 0.31; 95% CI= 0.41 to 0.58; p= 0.025) increased leptin expression.Conclusion: There is a difference in leptin ex­pres­­sion in the endometrium of PCOS compared to nor­mal.  Leptin expression is higher in the en­do­metrium of women with PCOS and obesity compared to nor­mal.Keywords: Leptin expressions, endometrium, polycystic ovarian syndrome.Correspondence: Dwi Sakti Berlian Besar. Department of Obs­tetrics and Gynecology, Faculty of Medicine, Universitas Sebelas Maret/ Dr. Moewardi General Hos­pital, Surakarta, Indonesia. Email: dwiesakti@student.uns.ac.id. Mobile: +628121845054Indonesian Journal of Medicine (2020), 05(01): 38-46https://doi.org/10.26911/theijmed.2020.05.01.06 
Effect of Dhikr on Blood Pressure in Pregnant Women with Hypertension Sari, Dian Nirmala; Djamil, Masrifan; Suwandono, Agus
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Hypertension is a 5-10% of complications in pregnancy and is one of the most common causes of death besides bleeding and infection, and also contributes to the mor­bidity and mortality of pregnant women. The purpose of this study was to examine effect of dhikr on blood pressure in pregnant women with hypertension.Subjects and Method: This was an experi­mental study conducted in Banjarnegara dis­trict health center, Central Java, in June 2018. A sample of 30 pregnant women with hyper­tension was selected for this study randomly. The dependent variable was blood pressure. The independent variable was dhikr. Blood pressure was measured by sphygmomano­me­ter. Mean difference between of systolic and diastolic blood pressure in two groups after intervention was tested by t test.Results: After intervention, diastolic blood pressure in the intervention group (Mean= 136.67; SD= 6.17) was lower than in the control group (Mean= 141.33; SD= 5.16), and it was statistically significant (p= 0.006). After inter­vention, diastolic blood pressure in the inter­vention group (Mean= 88.67; SD= 3.52) was lower than in the control group (Mean= 92.00; SD= 4.41), and it was statistically significant (p= 0.025).Conclusion: Dhikr decreases blood pressure in pregnant women with hypertension.Keywords: blood pressure, hypertension, pregnant womenCorrespondence: Dian Nirmala Sari. Applied Midwifery, Gra­duate Program, School of Health Polytechnics, Ministry of Health Semarang. Jl. Tirto Agung, Pedalangan, Banyumanik, Kota Semarang 50268, Central Java, Indonesia. Email: nirma­lasaridian@yahoo.co.idIndonesian Journal of Medicine (2020), 05(01): 87-94https://doi.org/10.26911/theijmed.2020.05.01.12
Clinical Profile of Patients with Manus Fracture Caused by Firecracker Blast Utomo, Pamudji; Siswanto, Totok
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Fireworks are traditionally used by various cultures or groups for celebrations. Estimated 10,000 to 12,600 people are injured because of fireworks in America every year. The type of fireworks that cause the highest injury is firecrackers with the incidence rate of 30% to 67% of all cases of injury due to fireworks. Indo­nesia is a country with the largest Muslim popu­lation in the world and firecrackers are often used to welcome Ramadan and Eid al-Fitr. This study aimed to report the Clinical pro­file of patients with manus fracture caused by firecracker blast.Case Presentation: The case study was taken from patients of Karima Utama Surgical Hos­pital, Surakarta, Indonesia, during Ramadan and Eid al-Fitr (from May 14 to June 15) 2018. A total of 36 patients were fractured due to firework explosions recorded in medical records during that period. Data such as gender, age and fracture diagnosis were collected in this study.Results: Males have a higher prevalence of 28 (78%) than female 8 (22%), with the highest group age between 11 to 20 years with 11 cases (31%) and more than 60 years being the lowest age group with 2 (6 %) cases of a total of 36 res­pon­dents. The right hand as the dominant hand has an injury incidence rate of 31 (86%) com­pa­red to the left hand 5 (14%) and more often oc­curs single fracture 22 (61%) compared to mul­ti­ple fractures 14 (39%) including the amputated phalanx.Conclusion: Our study showed 36 patients had fractures of the manus due to firecrackers, with the majority of male victims 28 (78%) and single manus fractures 22 (61%) with the right-hand dominance at the age between 11 to 20 years.Keywords: manus fracture, firecrackerCorrespondence: Pamudji Utomo. Department of Orthopedics and Traumatology Prof. Dr. R. Soeharso Orthopedics Hospital, Surakarta. Email: utomodr­@ya­hoo.­com.Indonesian Journal of Medicine (2020), 05(01): 57-62https://doi.org/10.26911/theijmed.2020.05.01.09
Clinical Manifestation, Surveillance, and Complication in Tuberous Sclerosis Complex in Dr. Moewardi Hospital Hamidi, Baarid Luqman; Mirawati, Diah Kurnia; Danuaji, Rivan; Subandi, Subandi; Budianto, Pepi; Hambarsari, Yetty; Prabaningtyas, Hanindya
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Tuberous Sclerosis Complex (Bour­neville’s disease) is genetic disorder with autosomal pattern of heritence that affecting differentiation sellular in many organ such as brain, lungs, cardiac with varible severity. Birth incidence is estimated to be 1:6000. The purpose of this study was to reported a case of patients with Bourneville’s disease (tuberous sclerosis complex) in Moewardi Hospital. Also reported surveillance and complication in this patient.Case Presentation: A male, 18 yearsold, with seizures, onset from infancy, tonic secondary generalized seizure pattern simultaneously throug­h­out the body. Neurologic status exami­nation found right hemiparese and mental re­tarda­tion, Encountered in patients with skin disorders such as butterfly appearance with facial angiofibroma, forehead fibrous plaque dan shar­green patch. Abnormalities also appeared in the oral mucosa as multiple papules. When psych­ological tests patient had difficulty following instructions. Psychiatric examination showed mode­rate lower intelegence. EEG results slow waves at left parietal, there is severe electro­fisio­logic abnormality considered structural lesi­on in left parietal. CT showed multiple calci­fied nodul­es in subependymal right and left lateral ventri­cle. MRI showed  atrophy and left sclerotic hip­po­campus with glosis in sub cortex occipito left parietal. To overcome the seizure patients given Carbamazepine. There was in­creas­ing of trans­aminase enzim, liver suspect liver angio­myo­lipoma.Conclusion: Based on clinical criteria for definite tuberous sclerosis complex patients met the criteria. The patients responded positively to carbamazepine that reduced seizure frequency. But somehow, patient's prognosis is worst. Pre­sence of intellectual impairment and neuro­psy­chiatric problems is a potential poor epilepsy control, and liver disfunction so that the necessa­ry comprehensive management and surveillance involves other disciplines.Keywords:Tuberous sclerosis complex, con­genital disorder, epilepsy, mental retardationCorrespondence: Baarid Luqman Hamidi.Department of Neuro­logy, Dr. Moewardi Hospital/Faculty of Medi­cine, Universitas Sebelas Maret. Email: ba­arid@­staff.uns.ac.idIndonesian Journal of Medicine (2020), 05(01): 47-51https://doi.org/10.26911/theijmed.2020.05.01.07
The Effectiveness of Albendazole-Levamisole and Mebendazole-Levamisole on the Intensity of Trichuris trichiura Infection in Elementary School Children Anto, Endy Juli; Siahaan, Jekson Martiar; Silitonga, Hendrika Andriana
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Trichuris trichiura worm infec­tion is still a major public health problem in Indo­­nesia, especially in peripheral areas. Until now, the search for antihelmintic combinations that have a high healing ability against T. tri­chi­ura infections and in the search for truly effective worm­ing is still being done. Albendazole and Mebendazole single doses still show limited ef­fi­ca­cy in the treatment of T. trichuria worms. The combination of Albendazole with Levamisol can increase effectiveness, but this combination still needs further investigation. Based on that fact, it is necessary to study the effectiveness compa­rison of the degree of infection intensity between the treatment of Albendazol-Levamisol and Me­ben­dazol-Levamisol against T. trichiura.Subjects and Method: A double blind ran­domized control trial was conducted at the State Elementary School in Medan, North Sumatera, from April to October 2019. A sample of 60 children was selected for this study. The depen­dent variable was the number of eggs decreased, the cure rate, and side effects. The independent variables were Albendazole 400 mg-Levamisol 50 mg/ 100 mg and Mebendazole 500 mg-Levamisol 50 mg/100 mg. The stools of elementary school children were examined using the Kato-Katz method to find eggs of T. trichiura infection. Data analysis was performed using the Chi square test. Results: Samples in the Albendazol-Levamisol and Mebendazol-Levamisol groups were 30 children, respectively. Children infected with T. trichiura consisted of 58 children of mild in­tensity (96.7%) and 2 children of moderate inte­nsity (3.3%). On the results of stool examination, a significant difference in the number of eggs decreased in the two groups was obtained (p <0.001) and 96.7% was the cure rate for T. trichiura infection in the two groups of Alben­dazol-Levamisol and Mebendazol-Levamisol. In this study, there were no significant differences in side effects in the two treatment groups.Conclusion: Treatment of T. trichiura infection with single doses of Albendazol-Levamisol and Mebendazol-Levamisol showed that there were sig­nificant differences in the Number of D­ecreased Eggs. Meanwhile, for the cure rate, there was no difference between the Albendazol-Levamisol and Mebendazol-Levamisol groups.Keywords: T. trichiura, Albendazole-Levamisol, Mebendazole-LevamisolCorrespondence: Endy Juli Anto. Department of Parasitology, Faculty of Medicine, Universitas Methodist In­donesia, Medan, Indonesia. Email: dr.endy­julianto@gmail.com. Mobile: +62-823 6766-7575Indonesian Journal of Medicine (2020), 5(1): 17-23https://doi.org/10.26911/theijmed.2020.05.01.03
Multiple Hereditary Exostosis of Distal Ulna with Dislocation of Radial Head: A Case Report Utomo, Pamudji; Idulhaq, Mujaddid; Brilianto, Bagus Iman
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Multiple hereditary exostosis of the forearm is typically formed in the distal ulna causing disturbances in the growth of the ulna and functional disability. Multiple hereditary exo­stosis inhibits the growth of the ulna leading to an acquisition of a varus deformity in the ra­dius which sometimes leads to dislocation of the radial head, the development of limitations in the pronation-supination of the forearm, and cos­me­tic problems. This study aimed to report the mul­ti­ple hereditary exostosis of distal ulna with dis­location of radial head.Case Presentation: We present a case of a 14 year-old girl with main complaint of a bony prominence on her right elbow which limits the elbow flexion range of motion. 3D CT-Scan re­vealed a dislocation of radial head, shortening and posterior bowing of ulna. We performed excision of the prominent radial head, recons­truction, and temporary arthrodesis of the elbow.Results: The forearm deformity in patients with multiple hereditary exostosis related to the cross-sectional area of the distal ulnar physis was only one-quarter of the distal radius, the distal ulna is more involved in the condition. There was more longitudinal growth at the distal ulnar physis than at the distal radial physis, the distal ulnar physis contributed more total Ulnar Length than the distal radial physis did to Radial length. Known surgical interventions including simple excision, ulnar lengthening, corrective radial os­teo­­tomy, hemi-epiphyseal stapling of the distal radius, the Sauve-Kapandji procedure.Conclusion: Simple excision could improve the range of movement of the forearm but would not halt the progression of disease, particularly in younger patients. It was not effective in con­troll­ing progression of the deformity. Mature patients did not recur, but in patients that had been excis­ed before puberty the results were varied and unpredictable.Keywords: multiple hereditary exostosis, radial head dislocation, excisionCorrespondence: Pamudji Utomo. Department of Orthopaedics and Traumatology Prof. Dr. R.Soeharso Ortho­paedics Hospital, Surakarta. Email: utomodr­@yahoo.com.Indonesian Journal of Medicine (2020), 05(01): 63-69https://doi.org/10.26911/theijmed.2020.05.01.10

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