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Jurnal Riset Kefarmasian Indonesia
Published by Asosiasi Pendidikan Diploma Farmasi Indonesia
ISSN : 2656131x     EISSN : 26558289     DOI : https://doi.org/10.33759/jrki
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
JURNAL RISET KEFARMASIAN INDONESIA adalah jurnal yang diterbitkan online dan diterbitkan dalam bentuk cetak. Jurnal ini diterbitkan 3 kali dalam 1 tahun (Januari, Mei dan September) Jurnal ini diterbitkan oleh APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) Lingkup jurnal ini mencakup Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Organik Bahan Alami, Biokimia, Analisis Kimia, Kimia Fisik, Biologi, Mikrobiologi, Kultur Jaringan, Botani dan hewan yang terkait dengan produk farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Nutrisi dan Kesehatan Masyarakat.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 215 Documents
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UJI SIFAT FISIKOKIMIA SEDIAAN EKSTRAK DAUN ALPUKAT (Persea americana Mill.) DENGAN VARIASI KONSENTRASI ASAM STEARAT Putri, Divia Tamara; Azzahra, Fara
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 3 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/e37xby94

Abstract

The content of avocado leaf extract such as polyphenol, saponins, alkaloids, tannins, quercetin and flavonoids can be made anti-acne cream preparations. This study aims to determine the physicochemical properties of avocado leaf extract cream including organoleptic tests, homogeneity tests, pH tests, and spread diameter tests. The research method used is experimental research with a posttest only design methodology. Avocado leaf extract is made in cream preparations using a stearic acid base, namely with variations in concentrations of F1(10%), F2(12.5%), and F3(15%). Data analysis used the oneway ANOVA test and the LSD test to determine the difference between variations in stearic acid concentrations in avocado leaf extract cream. The results of the research on organoleptic and homogeneity tests were carried out descriptively showed that F1 was light green, had a distinctive smell of avocado leaf extract, slightly thick, F2 was green color and F3 was brownish green, both of which have a distinctive odor of avocado leaf extract and are thick. Homogeneity shows the three formulas are not homogeneous. The pH test results were F1(7.85±0.05), F2(6.97±0.03) and F3(6.79±0.02) which had significant differences. The spread diameter results are F1(5.70±0.53cm), F2(5.56±0.35cm) and F3(5.36±0.31cm) have no significant differences. Organoleptic, pH and spread diameter tests meet the requirements whereas homogeneity tests do not meet the requirements. The factor of adding avocado leaf extract to the preparation and the unstable mixing speed, because it is done manually using a mortar and stamper, affects the homogeneity of the cream produced.
FORMULASI DETERJEN RAMAH LINGKUNGAN DENGAN SERBUK SIMPLISIA DAUN WARU (Hibiscus tilliaceus L.) DAN BUAH LERAK (Sapindus rarak DC.) SEBAGAI SURFAKTAN Nurrosyidah, Iif Hanifa; Putri, Erica Novia; Satria, Berlian Adi
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.346

Abstract

The purpose of this study was to develop an environmentally friendly detergent formula containing simplicial powder of hibiscus leaf (Hisbiscus tiliaceus L.) and lerak fruit (Sapindus rerak DC.) and combined with biodegradable surfactants (Decyl Glucoside and Lauryl Glucoside) so that they are easy to biodegrade. The research method includes making liquid detergent using three formulas, namely F I, F II, and F III with variations in the concentration of hibiscus leaf and lerak fruit simplicial powder used. Physical characteristic test of liquid detergent according to the quality requirements of SNI SNI 06-4075-1996 includes organoleptic, pH, foam stability test, and contamination analysis by determining the total plate number (ALT). Based on the results of this study, the three detergent formulas have physical characteristics according to the quality requirements of SNI
PENGARUH KONSELING APOTEKER TERHADAP TINGKAT KEPATUHAN MINUM OBAT DAN KADAR GULA DARAH PASIEN DIABETES MELLITUS Rahmawaty, Annis; Anggraeni, Nanda Widia
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.349

Abstract

Background: Diabetes mellitus is a metabolic disorder characterized by high blood sugar levels. The level of adherence to taking medications plays a very important role in achieving successful treatment and maintaining blood sugar levels within normal ranges, as well as pharmacist counseling is very important in handling DM. Objective: The purpose of this study was to determine the effect of pharmacist counseling on the level of adherence to taking oral antidiabetic drugs in diabetes mellitus patients at the Ngembal Kulon Kudus Health Center. Method: This study is a pre-experimental study designed by One Group Pretest Posttest with cross-sectional data retrieval. Data collection was carried out in March-April 2022 at the Ngembal Kulon Kudus Health Center. Result: This study used spearman correlation test with 0.000 results obtained, wilcoxon test obtained 0.000 results and the paried T-test obtained results of 0.000 which were said to be significantly different before and after pharmacist counseling. Conclusion: Counseling there was a change in compliance in diabetes mellitus patients there was an effect of providing pharmacist counseling on the level of adherence to taking oral antidiabetic drugs using the MGL MAQ questionnaire (p 0.000) and blood sugar levels in demographic data (p 0.000) in diabetes mellitus patients.
EFEK LARVASIDA EKSTRAK ETANOL DAUN BINTANGUR (Chalophyllum inophyllum L.) TERHADAP MORTALITAS LARVA NYAMUK AIR KOTOR (Culex sp.) Nurpermatasari, Adhisty; Faisal, Ahmad Purnawarman; Nasution, Pratiwi Rukmana
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 2 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i2.350

Abstract

The Bintangur plant is a plant that can often be found around the house, its existence as a plant makes its properties less known to the public, all parts of this plant are known to be very useful for various pharmacological effects. Various efforts to prevent diseases transmitted by Culex sp. one of them uses larvicides, so an alternative larvicide from natural ingredients is needed, namely Bintangur. The purpose of this study was to determine the activity of the ethanol extract of Bintangur leaves in killing Culex sp larvae with the control being the larvae that were not given the ethanol extract of Bintangur leaves. The type of research on the activity test of the Bintangur leaf ethanol extract used an experimental research type with a true experiment design with a posttest only control group design. The results showed that the ethanol extract of Bintangur leaves (Chalophyllum Inophyllum L.) was active in killing Culex sp. larvae. with the results of the Reed and Muench test with an LC50 value of 281.84 ppm
UJI EFEK ANALGESIK EKSTRAK DAUN SIRIH HIJAU BANYUWANGI (Piper betle L.) PADA MENCIT PUTIH JANTAN (Mus musculus) Lestari, Ima Fitria; Syafirah, Junieta Fara; Deviani, Dita Amanda
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.351

Abstract

The content of flavonoid compounds in betel leaf is used as a protection as analgesic. The purpose of this study was to test the analgesic effects of Banyuwangi green betel leaf extract (Piper betle L.) on male white mice (Mus musculus). The doses of green betel leaf ethanol extract that were used were 4.696 mg, 9.392 mg and 18.784 mg and the positive control were mefenamic acid. The test animals used in this study were white male mice (Mus musculus) that were adapted for about 3 days in experimental environmental conditions. Based on the results of the study, the analgesic effect test of green betel leaf extract (Piper betle L.) can provide analgesic effectiveness on mice (Mus musculus). Ethanol extracts of green betel leaf (Piper betle L.) at doses of 4.696 mg/kgBW were able to provide a good analgesic effect with good responses to white male mice (Mus musculus). The percentage of analgesic power that was close to the percentage of analgesic power of the gold standard which is 69.23%.
PENYEBAB OBAT KEDALUARSA, OBAT RUSAK DAN DEAD STOCK (STOK MATI) DI GUDANG PERBEKALAN FARMASI GUDANG PERBEKALAN FARMASI RUMAH SAKIT X SURABAYA Nurcahyani, Diah; Ayuningtyas, Arina; G, Leo Eladisa
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.353

Abstract

Drug processing problems in each hospital often occur nowadays, so it is necessary to carry out continuous evaluation to create optimal services in providing good quality patient health. This study aims to describe and analyze the occurrence of expired drugs, damaged drugs and dead stock, to provide policy recommendations for improving drug processing. This study uses a descriptive method, namely research that describes an object in relation to the actual situation. The sample used in this study is the number of expired drugs, damaged drugs and dead stock for the period June - August 2021 compared to the total number of drugs in the hospital. The percentage results for expired drugs were 0.002%, damaged drugs were 0%, dead stock were 0.022%, this was due to changes in prescribing patterns, expiration dates that were too short when receiving drugs from PBF and not maximally checking expired drugs in each unit, so it is necessary to do checking between planning and drug needs as well as improving the ED drug processing system and evaluating the system and evaluating the drug acceptance system in hospitals.
KANDUNGAN BORAKS PADA PENTOL BAKSO DI KECAMATAN BALONGBENDO KABUPATEN SIDOARJO DENGAN METODE SPEKTROFOTOMETRI Sari, Adinda Puspita; Setyawati, Herni; Zaenudin, Djelang
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.354

Abstract

Sodium Tetraborate, also known as Borax, is a chemical compound which is a derivative of metal boron gas (B), used as an antifungal compound, wood preservative, and an antiseptic compound in cosmetics. The use of Borax as a preservative in food has been banned by the government. The purpose of this study was to help and remove the levels of borax found in meatball bulbs. Sampling was determined in Balongbendo District, Sidoarjo Regency. Analysis of the content of Borax compounds in meatball bulbs was carried out qualitatively using the flame method and the tumeric paper test. Quantitative test using the UV-Vis Spectrophotometer method. Based on the results of an analysis of 60 samples of meatball bulbs sold in Balongbendo District, Sidoarjo Regency, 1 sample was positively identified as containing a Borax compound with an average level of 0.162 ppm.
UJI AKTIVITAS ANTIBAKTERI SEDIAAN SABUN CAIR MINYAK ATSIRI KULIT BUAH JERUK BALI (Citrus maxima) Yustisi, Andi Juaella; Wahyuningsih, Sri; Auliah, Nielma
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 2 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i2.355

Abstract

Pomelofruit (Citrus maxima) has several chemical compounds, one of which is essential oil, 6.68g of essential oil was found in the peel of the pomelofruit (Citrus maxima) which has an active compound, namely limonene (94.96%). The essential oil provided strong antibacterial activity against S. aureus isolates. The purpose of the study was to formulate the essential oil of pomelofruit peel (Citrus maxima) into liquid soap preparations that met physical stability and to test the antibacterial activity of liquid soap preparations of pomelofruit (Citrus maxima) peel essential oil against S. aureus bacteria. The method used in testing the stability of liquid soap preparations is cycling test and in the antibacterial activity test using the Disk diffusion method. The results obtained that the essential oil of pomelofruit peel (Citrus maxima) can be formulated in the form of liquid soap because it meets the physical stability test, namely before and after the cycling test and activity tests. antibacterial against S. aureus. at 1% concentration of 18.9mm (strong), 3% of 20.4mm (very strong), and 5% of 21.1mm (very strong). Based on this, the essential oil of pomelofruit peel (Citrus maxima) can be made into liquid soap preparations that meet the physical stability test and have antibacterial activity in very strong category at a concentration of 5% in inhibiting the growth of S. aureus bacteria.
FORMULASI DAN UJI IRITASI SEDIAAN LULUR KRIM CANGKANG SOTONG (Sepia sp.) TERHADAP KELINCI (Oryctolagus cuniculus) Arifin, Arfiani; Ida, Nur; Rosmiyanti, Rosmiyanti
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.359

Abstract

Cuttlefish shell (Sepia sp.) contains calcium carbonate which has benefits in removing dead skin cells, regulating skin pigmentation, shrinking pores, removing acne and black spots and making skin brighter. The aims of this study were to formalize dosage form of cuttlefish shell cream scrub (Sepia sp.) that meets the physical quality requirements and to determine the potential irritation of cuttlefish shell (Sepia sp.) cream scrubs in rabbits (Oryctolagus cuniculus). Reseacrh methods include the dosage form of cuttlefish shell powder using sieve mesh 44, cream scrub formulations with variations in cuttlefish shell powder concentrations by 15%, 20% and 25%. Physical quality test carried iut includes organoleptic tests, homogeneity tests, scatter power tests and sticking power tests. The cream scrub formula irritation test was carried out by patch test method in rabbit test animals. The results of the study obtained that cuttlefish shell cream scrubs have qualified physical quality tests and the degree of irritation value of F1 cream scrubs (cuttlefish shell 15%) of 0,2 which is categorized means very mild irritation.
IDENTIFIKASI SENYAWA ANTIOKSIDAN DARI EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius) DENGAN METODE 2,2-DIPHENYL-1-PICRYL-HYDRAZYL ( DPPH ) Hashary, A Rufaidah; Damayanti, Utami Putri; Rusdiaman, Rusdiaman; Nurzak, An Nisaa
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 2 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i2.360

Abstract

Pandan wangi (Pandanus amaryllifolius) is one type of monocotyledonous in the Pandanaceae family that has leaves with a characteristic fragrant aroma. There is a chemical content in the leaves of pandan wangi (Pandanus amaryllifolius) namely alkaloids, flavonoids, saponins, tannins, and polyphenols that can be used as natural antioxidants. This study aims to identify the presence of antioxidant compounds in ethanol extract of pandan wangi leaves (Pandanus amaryllifolius). The research method is an experimental method. The extraction process by maceration and antioxidant testing of pandan wangi leaves (Pandanus amaryllifolius) ethanol extract used the DPPH method where Vitamin C being a positive control, and IC50 value as a parameter. The results stated that ethanol extract of Pandan wangi leaves (Pandanus amaryllifolius) has antioxidant activities that are classified as effective with an IC50 value of 27.65 ppm, while Vitamin C as positive control is classified as an effective antioxidant with an IC50 value of 2.58 ppm. Based on the results of the research that has been done, it can be concluded that the ethanol extract of Pandan Wangi leaves has a good antioxidant content in counteracting free radicals.

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