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INDONESIA
Science Midwifery
ISSN : 20867689     EISSN : 27219453     DOI : -
Core Subject : Health,
Jurnal Kebidanan dan ilmu kesehatan ini adalah di terbitkan 2 kali dalam setahun, dalam bidang kebidanan dan perawat.
Articles 1,455 Documents
Lipid-based nanoparticle delivery system approach for diabetic wounds: A review Choerrunisa, Choerrunisa; Jafar, Garnadi; Sukmawati, Ika Kurnia
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2148

Abstract

Diabetic wounds are a chronic complication that is difficult to heal due to impaired blood circulation, oxidative stress, and microbial infection. Conventional therapies are often ineffective due to poor drug penetration into damaged skin tissue and limited bioavailability of active compounds. Lipid nanoparticle-based drug delivery technology was developed to overcome these obstacles by increasing stability, skin penetration ability, and controlled drug release. Objective: This article aims to comprehensively review the role of lipid-based nanoparticle delivery systems in improving the effectiveness of diabetic wound healing therapy, including the mechanisms of absorption enhancement, active substance stability, and pharmacological activity. Methods: This study is a systematic literature review of national and international publications over the past ten years (2015–2025). Data sources were obtained from PubMed, ScienceDirect, and Google Scholar databases using keywords “lipid nanoparticles,” “diabetic wound healing,” and “transdermal drug delivery.” Inclusion criteria included experimental studies and review articles discussing lipid nanoparticle formulations and their therapeutic effects on diabetic wounds. Results: Various studies have shown that lipid-based nanoparticle systems, including nanostructured lipid carriers (NLCs) and solid lipid nanoparticles (SLNs), can improve the stability and permeation of active ingredients such as curcumin, asiatic acid, and other herbal extracts through the skin. This improvement contributes to better anti-inflammatory, antioxidant, and antibacterial activities, thereby accelerating the healing process of diabetic wounds. Conclusion: Lipid-based nanoparticle technology offers an innovative approach to diabetic wound therapy by improving the stability, bioavailability, and effectiveness of active ingredients. Further development is needed for formulation optimization and clinical validation to ensure the safety and effectiveness of its use in diabetic patients.
Comparison of rebozo technique and warm compress on reducing pain intensity in pregnant women during the active phase i in the working area of Wanayasa Health Center, Purwakarta Regency, 2025 Rosyeni, Yeni
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2154

Abstract

Labor pain can lead to decreased contractions and prolonged labor. According to World data in the World Health Organization in 2019, the case of mothers with painful labor states that only 10-15% of labor lasts without pain, thus the data is most found in mothers with painful labor, namely a prevalence of 85-90% of labor takes place with pain. The rebozo technique and warm compress are new non-pharmacological therapies to reduce the intensity of labor pain that are easy, inexpensive, and comfortable for mothers. Objective: To find out the comparison of rebozo technique and warm compress on the intensity of pain reduction in pregnant women during the first active phase. Research Method: The type of research is Quasi experiment pre-test and post-test two group design. Technique of sampling purposive samples. The data were analyzed by paired T test and Wilcoxon test. Results: The results of the analysis showed that the average respondent after being given the rebozo technique experienced a decrease in pain of 3.27, while the respondents after being given warm compresses experienced a decrease in pain of 4.87 with a p-value of 0.006 so it was concluded that there was a significant difference in the reduction in the intensity of labor pain given by the rebozo technique and warm compress, where the rebozo technique was more effective compared to the administration of warm compresses. Suggestion: Apply the natural method of the rebozo technique during the delivery process as one of the mother's loving care that will provide a sense of comfort and can reduce labor pain in childbirth mothers.
Overview of patient responses to pain stimuli based on glasgow coma scale (GCS) scores Malik, Abdul; Huriani, Emil; Mailani, Fitri
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2155

Abstract

Decreased consciousness is a clinical condition that requires rapid and accurate assessment. One method used is the application of nail bed pressure pain stimulation to elicit a response from the patient. This study aims to determine the consistency of responses from patients with decreased consciousness when given pain stimulation based on the Glasgow Coma Scale (GCS) score in the emergency department of Dr. M. Djamil Hospital in Padang. This was a quantitative descriptive study with 70 respondents selected using purposive sampling. Consciousness levels were measured twice. Data were collected in July 2025 using the GCS assessment format, then analyzed descriptively and cross-tabulated using frequency distribution, percentages, means, standard deviations, and correlations. The nail bed pressure technique produced an average GCS score of 6.01 ± 0.625 on the first assessment and 6.04 ± 0.711 on the second assessment. Most scores were in the range of 6–7. The nail bed pressure technique provided an inconsistent picture of changes in GCS responses in patients with decreased consciousness.
Analysis of parental communication and sexual risk behavior among adolescents based on gender Harahap, Yanna Wari; Nurlaila, Nurlaila; Harahap, Irawati; Antoni, Adi; Hasibuan, Ahmad Safii; Suryati, Suryati
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2121

Abstract

Adolescents are a group that is highly vulnerable to risky sexual behaviors. One of the factors influencing such behaviors is communication between parents and children. Good communication can serve as a protective factor against unhealthy sexual behavior. This study aims to analyze the influence of parent–child communication on risky sexual behavior among adolescents, as well as its differences based on gender. The study employed an analytical quantitative design with a cross-sectional approach. The sample consisted of 120 male and female adolescents selected through proportional random sampling. Data were collected using standardized questionnaires that had been tested for validity and reliability. Analysis was conducted using Pearson correlation and Independent t-test with a significance level of 0.05. The results showed a significant negative correlation between parental communication and risky sexual behavior (r = –0.65; p < 0.001). The better the communication between parents and adolescents, the lower the level of risky sexual behavior. Gender differences were also observed, where female adolescents demonstrated higher communication scores and lower risky sexual behavior compared to males (p < 0.001). Effective communication between parents and children plays a crucial role in preventing risky sexual behaviors among adolescents. Strengthening family communication through reproductive health education programs involving active parental participation is essential.
The effect of aerobic exercise on blood sugar control in diabetes mellitus patients Haritsah, Nurul Fithriati; Kurniawati, Dwi
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2150

Abstract

Diabetes mellitus is a global health problem with increasing prevalence. According to data from the International Diabetes Federation (1), more than 537 million people worldwide suffer from DM. Aerobic exercise has been recommended as a non-pharmacological intervention to control blood glucose levels, but further research is needed to determine its effectiveness in various clinical contexts. Various measures are taken to prevent and control diabetic neuropathy and improve peripheral circulation through the five pillars of DM management, namely education, nutrition, physical activity, pharmacological therapy, and blood glucose monitoring. Physical activity is an important element in preventing and managing type 2 DM. Aerobic exercise is a series of deliberately selected movements that follow the rhythm of music that is also selected so as to create certain rhythmic, continuity, and duration provisions. Subjects and Method: This study used 30 subjects with a quasi-experimental method with one group pretest and posttest design with control. The total sample was 30 patients, namely 15 in the intervention group and 15 in the control group. This study was conducted on subjects aged 40-60 years in Tohudan Village, Colomadu, Karanganyar. The intervention group underwent an aerobic exercise program three times a week for 12 weeks, while the control group did not receive any intervention. Blood sugar levels were measured before and after the intervention. Results: There was a significant effect between random blood glucose levels in patients given the intervention, with a mean difference of -46,000, indicating that after being given an aerobic exercise intervention, random blood glucose could decrease by about 46 mg/dl. Conclusion: There is an effect of aerobic exercise on blood sugar control in patients with diabetes mellitus.
Development of a natural nanostructured lipid carrier (NLC)-based delivery system as an antidiabetic and diabetic wound agent: A review Novianti, Tamia Rizqi; Kusriani, R. Herni; Jafar, Garnadi
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2152

Abstract

Diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia due to impaired insulin secretion. Diabetes often causes serious complications such as diabetic wounds, which are characterized by the appearance of ulcers, infections, or tissue damage in the feet. Conventional therapeutic approaches often show less than optimal effectiveness due to limited drug penetration into damaged skin tissue. The use of natural ingredients with antidiabetic and wound healing activities has been widely studied, but their effectiveness is often hampered by low solubility, stability, and bioavailability. One innovative strategy to overcome these problems is the development of nanotechnology-based drug delivery systems, one of which is Nanostructured Lipid Carrier (NLC). NLC is a lipid delivery system that combines solid and liquid lipids to increase stability, drug loading capacity, and control the release of active compounds. Purpose: This article aims to review the development of formulations from natural ingredients that have potential as antidiabetic and diabetic wound healing activities. Methods: This study is a literature review of articles published in the last ten years (2015 – 2025) from the ScienceDirect, PubMed, and Google Scholar databases. Results: Based on several studies, it shows that various active compounds such as curcumin (Curcuma longa), bay leaves (Syzygium polyanthum), and other flavonoid compounds have been formulated in the NLC system with significant improvements in stability, bioavailability, and pharmacological effectiveness. Conclusion: The NLC-based drug delivery system from natural ingredients has proven potential in increasing the effectiveness of antidiabetic therapy and diabetic wound healing. Further research is needed to optimize formulation stability, long-term toxicity testing, and clinical validation to support its therapeutic application.
The effect of baby massage and baby spa on weight gain in 3-9 month-old babies at Mahanum Clinic Fauziah, Yaumil; Nasution, Yulia Fatma; Sitorus, Nopita Yanti; Lubis, Desi Handayani; Nasution, Annisa Namirah; R, Maimunah
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2158

Abstract

Child developmental disorders occur when genetic or environmental factors fail to meet a child's basic growth and development needs. Prompt detection and appropriate intervention can help improve the quality of a child's growth and development later in life. This study aimed to determine the effect of infant massage and baby spa treatments on weight gain in infants aged 3 to 9 months. This was a quasi-experimental study using a pre-test-post-test with a control group design. The subjects consisted of 20 infants in the case group and 20 infants in the intervention group at Mahanum Clinic. The results showed that the average weight gain in infants aged 3-9 months in the intervention group was 740.48 grams, while the average weight gain in the control group was 206.48 grams. The results of the Paired Sample T-test showed a p-value of 0.000 < 0.05, indicating that both baby spa and baby massage have an effect on the weight of babies aged 3-9 months. The results of the Independent T-test showed a p-value of 0.004 < 0.05, indicating that there is a significant difference between baby spa and baby massage on the weight of babies aged 3-9 months, with baby spa being superior to baby massage. It is recommended that midwives use baby spa as an appropriate health promotion strategy to increase infant weight.
Maternal compliance with complete basic immunization: The role of knowledge, family support, and anxiety Faradila, Putri; Andarsini, Mia Ratwita; Farizi, Sofia Al; Sulistiawati, Sulistiawati
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2164

Abstract

Complete basic immunization plays a crucial role in public health efforts to protect infants from infectious diseases and to decrease child morbidity and mortality. Despite its importance, the coverage of complete basic immunization in the Socah Community Health Center area remained low at 44.7%, which did not meet the national standard. This situation reflects inadequate maternal adherence in providing immunizations for their children. The present study aimed to examine the association between maternal knowledge, family support, and anxiety levels with their adherence to complete basic immunization. An analytic observational design with a cross-sectional approach was utilized. Eighty-three mothers with children aged 12–24 months were chosen through proportionate cluster random sampling. Data collection was conducted using structured questionnaires and immunization record reviews, and analyzed through the Chi-square test at a significance level of 0.05. Findings revealed significant associations between knowledge (p = 0.005), family support (p = 0.039), and anxiety (p = 0.007) and maternal adherence to immunization. Mothers possessing better knowledge, stronger family backing, and lower anxiety levels tended to follow the immunization schedule more consistently. The study suggests strengthening educational interventions and psychological support programs for mothers and families to enhance complete basic immunization coverage in the community.
Article review: The role of probiotics in maintaining balance intestinal microbiota on diarrhea infection therapy Solihah, Nurlaella; Mulyani, Yani; Kaniawati, Marita
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2165

Abstract

Diarrhea infections are a significant global health problem, especially in developing countries and can be caused by bacterial, viral or parasitic infections. Antibiotics are often given times ineffective in long-term use and risk disrupting the balance of intestinal microbiota. So that probiotics are needed that come from living microorganisms that provide health benefits if consumed in sufficient quantities. Review This article aims to review the role of probiotics in maintaining the balance of intestinal microbiota and their effectiveness in diarrheal infection therapy. Through literature analysis, several probiotic strains such as Lactobacillus and Bifidobacterium have shown their ability to inhibit the growth of pathogens, such as Escherichia coli and Clostridium difficile, through nutrient competition, production of antimicrobial substances, and immune modulation. This article concludes that probiotics have great potential as an additional therapy that is safe, effective and has minimal side effects in treating diarrheal infections. However, further studies are needed to determine the optimal dose, duration of use, and effectiveness of probiotics in various populations and types of diarrhea.
The effect of body mass index and position on blood surface area on sanitary pads Fauziah, Siska Febrina; Lestaluhu, Viqy; Kurniawati, Imas; Mardiani, Dita Eka; Diana, Helmi
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2168

Abstract

Accurate measurement of postpartum blood loss is crucial for guiding appropriate medical interventions. Digital image processing offers potential to enhance visual estimation accuracy, though refinement is still needed for sanitary pad media. This study examined the effect of body mass index (BMI) and body position on the blood surface area on sanitary pads to support the development of digital image-based measurement methods. An experimental design simulated postpartum blood loss using three BMI categories (underweight, normal, overweight) and three positions (sitting, side-lying, supine), each repeated twice. Blood surface area was measured using digital image processing and analyzed with the Kruskal-Wallis and Friedman tests. The sanitary pads’ absorption capacity ranged from 70–80 mL. Blood surface area did not differ significantly by BMI (p=0.597) but varied significantly by position (p=0.000). A trend of increasing surface area with higher BMI was observed. These findings suggest that both BMI and position should be considered in refining digital image-based methods for accurate and objective postpartum blood loss measurement.

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