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Andika Aliviameita
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Medicra (Journal of Medical Laboratory Science/Technology)
Published by Universitas Muhammadiyah Sidoarjo
ISSN : 25807730     EISSN : 25807730     DOI : https://doi.org/10.21070/medicra
Core Subject : Health,
Health Professions Public Health
Focus : to facilitate scholar, researchers, and lecturers for publishing the original articles of review articles. Scope : Medicra publishes research articles in the field of “medical laboratory (science/technology)” with the following scope: Clinic Chemical Hematology Microbiology Parasitology Immunology Food and beverage analysis Chemical Molecular Diagnostics Toxicology Cytology Histology Epidemiology Laboratory Management Laboratory Quality Control
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 121 Documents
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Identification of Salmonella Sp Bacterial Contamination in Broiler Chicken at Pon Market, Jombang Regency: Identifikasi Cemaran Bakteri Salmonella Sp Pada Daging Ayam Broiler Di Pasar Pon Kabupaten Jombang Rizki, Ramadhani Putri; Arifin, M. Zainul; Aini, Inayatul
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1621

Abstract

Broiler chicken meat is a type of meat that is much favored by the public because of its high nutritional content with good taste and relatively low price. However, the high protein and water content causes this meat to be easily contaminated by microbes, one of which is Salmonella sp. Salmonella sp can cause Salmonellosis, in humans salmonellosis is transmitted through food because it is undercooked during cooking so that Salmonella sp bacteria enter the body. To determine the presence of Salmonella sp bacteria in broiler chicken meat in the pound market, Jombang district. The design of this research is descriptive. The sample of this research was obtained from 8 chicken traders with total sampling technique. The variables in this study were salmonella sp bacteria in broiler chicken meat. This research method uses the scratch method. The results of the 8 samples of broiler chicken examined were found to be half(50%) contaminated with Salmonella sp and half(50%) not contaminated with Salmonella sp. From this study it was found that half of the population of broiler chicken meat sold in the pound market was contaminated with Salmonella sp.
Analysis of C-Reactive Protein (CRP) Levels in Venous and Capillary Blood Samples with Immunoturbidimetric Methods: Analisa Kadar C-Reactive Protein (CRP) Pada Sampel Darah Vena Dan Darah Kapiler Dengan Metode Imunoturbidimetri Bastian, Bastian; Sari, Indah; Pratama, Feronica Putri
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1622

Abstract

Inflammation or inflammation occurs due to bacterial infection, detection of inflammatory infection can be done by laboratory tests. An examination that can help diagnose and detect abnormalities in the body. One of the parameters for examining inflammation markers is C-Reactive Protein (CRP). CRP examination usually uses venous blood because venous blood is more often used in laboratory examinations. The purpose of this study was to determine differences in CRP levels in venous and capillary blood. This study uses a posttest only design research. Samples were taken from DIV Technology Medical Laboratory IkesT Muhammadiyah Palembang students with total sampling technique. The research was carried out at the Hematology Laboratory of IKesT Muhammadiyah Palembang on December 21, 2021. Based on the results of research that has been carried out on the analysis of C_Reactive Protein levels in venous blood and capillary blood samples using the immunoturbidemteri method, the results showed that the average CRP level of venous blood was 9.6 and average the average capillary blood CRP level was 8.33. Thus it can be concluded that there is no significant difference in the examination of CRP levels in venous and capillary blood.
Difference between Uric Acid and Albumin Levels in Chronic Kidney Failure Patients Before and After Hemodialysis : Perbedaan Kadar Asam Urat dan Albumin Pada Pasien Gagal Ginjal Kronik Sebelum dan Sesudah Hemodialisis Maha, Maha; Puspitasari, Puspitasari
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1623

Abstract

Chronic kidney failure (CKF) is a decrease in kidney function has decreased. The impact that occurs is the accumulation of metabolic waste, including fluid overload, uremia, hyperuricemia and hyperkalemia. Hemodialysis is the process of cleansing the blood through a distillation process outside the body using a machine (dialyzer). The purpose of this study was to determine the differences in uric acid levels and albumin levels in patients with chronic renal failure before and after hemodialysis at Dr. Muhammad Zyn Sampang General Hospital. This type of research is experimental with 15 patients using purposive random sampling technique. The method of examining uric acid using Enzymatic Photometry, and the method of examining albumin using Bromocresol Green. The research was conducted in April-May 2021 at RSUD Dr. Muhammad Zyn Sampang. This study used the Wilcoxon test. It can be concluded that there is a significant difference (p <0.05) uric acid levels (p = 0.001) and albumin levels (p = 0.001) in patients with chronic renal failure before and after hemodialysis.
Test of Lead (Pb) and Zinc (Zn) on Tiger Shrimp (Penaeus monodon) at Kalanganyar Market, Sidoarjo with Atomic Absorption Spectrophotometer (AAS) : Uji Kadar Timbal (Pb) dan Seng (Zn) pada Udang Windu (Penaeus monodon) di Sidoarjo Dengan Metode Atomic Absorption Spectrophotometer (AAS) Sejati, Risqi Agil Wahyu; Hanum, Galuh Ratmana; Pramushinta, Intan Ayu Kusuma
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1624

Abstract

Sidoarjo City in East Java Province has a pond area of up to 7.68%. One of the cultivations developed in ponds is tiger shrimp (Penaeus monodon), which are mostly sold in Sidoarjo. The presence of metals in aquatic bodies comes from natural sources that enter can be the erosion of mineral rocks found in the aquatic environment. Tiger shrimp is one type of shrimp that is preferred by most Indonesian people. If this shrimp is contaminated by heavy metals, it will harm the people who consume it. This research was conducted to find out the levels of heavy metals Timbal (Pb) and Seng (Zn) contained in tiger shrimp (Penaeus monodon) windu shrimp in the market of Sidoarjo with the Atomic Absorption Spectrophotometer (AAS) method. This research was conducted at the Laboratory of Applied Chemical Technology Medical Laboratory of the Faculty of Health Sciences, University of Muhammadiyah Sidoarjo and the Chemistry Laboratory of FMIPA of Maulana Malik Ibrahim University of Malang. Data analysis methods use measurement and observation as well as descriptive statistical analysis. The results of heavy metal levels in this study obtained the highest levels of lead heavy metals (Pb) of 0.596 mg/kg while the lowest levels amounted to 0.544 mg/kg and the highest levels of zinc heavy metals (Zn) amounted to 3.930 mg/kg while the lowest levels amounted to 3.016 mg/kg.
Predictive Analysis of NLR, Absolute Lymphocyte Count, and CT-Value on The Severity of Covid-19 Patients: Analisis Prediksi NLR, Absolute Lymphocyte Count, dan CT-Value Terhadap Derajat Keparahan Pasien Covid-19 Bastiana; Donastin, Adyan; Arista, Devi Maya; Surya, Prima Ardiansah
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1625

Abstract

Laboratory parameters in Covid-19 patients may have a relationship with the clinical severity of the patient on arrival. This study aims to Analyzing the relationship between NLR, ALC, and CT values with the clinical severity of Covid-19 patients on arrival. A total of 101 subjects were collected from medical records of RSI Jemursari Surabaya from April to September 2020. The correlation laboratory parameters (NLR, ALC, and CT-value) with the severity of Covid-19 patients (mild, moderate, severe and critical) were analyzed using One Way Anova and Kruskal Wallis. The relationship of NLR with severity (p-value=0.143), ALC with severity (p-value=0.165), and CT-value with severity (p-value= 0.987). Patients with COVID-19 tend to have a high NLR in all clinical conditions. The mean value of the ALC was within normal limits for all degrees of severity. There is no significant relationship between NLR, ALC, CT-value with the severity of Covid-19 patients.
Antibacterial Activity Of Plants Extract Drug Effective Against Pseudomonas aeruginosa Antibiotics Resistance To Quinolone And Cephalosporine: Aktivitas Antibakteri Ekstrak Tanaman Berkhasiat Obat Terhadap Bakteri Pseudomonas aeruginosa Resisten Antibiotik Quinolon Dan Sefalosporin Kurniawan, Edy; Halid, Idham; Agustina, Agustina
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1627

Abstract

Antibiotics are empirically used as drugs to treat bacterial infections, but the irrational use of antibiotics causes bacterial resistance to certain antibiotic regimens, therefore solutions are needed to explore alternative drugs. This study aims to explore medicinal plants that are able to inhibit Pseudomonas aeruginosa bacteria that are resistant to quinolones and cephalosporins. The method used is descriptive observational and antibacterial activity test of plant extracts using the well diffusion method. Three plant extracts were used, binahong extract (Andredera cordifolia), tomato fruit extract (Lycopersicon esculentum), and aloe vera extract (Aloe vera). The results showed that only tomato extract inhibited Pseudomonas aeruginosa bacteria with a strong category, while binahong and aloe vera extracts could not inhibit the test bacteria. It was concluded that tomato fruit extract might be an alternative as a medicinal plant because it was able to inhibit P. aeruginosa resistant to quinolones and cephalosporin antibiotics.
Sigma Matrix of Ureum and Creatinine in Some Laboratories: Overview: Gambaran Matrik Sigma Pemeriksaan Ureum dan Kreatinin pada Beberapa Laboratorium Salsabella, Ainun; Aryani, Titin
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1628

Abstract

In clinical diagnosis, 80% is based on laboratory examination, however, laboratory examination still often cause errors, so it is necessary to apply a sigma matrix to evaluation. This study goes on to explain the results of previous studies on the sigma urea and creatinine matrix results in various laboratories. A literature review strategy was used in the research. A variety of databases, including Pubmed, Proquest, and Willey Library Online, were used to choose the literature. Ten publications were selected as literature sources and were quantitatively analyzed descriptively. The lowest urea sigma matrix value was 1.3, and creatinine was -2.33, according to data from numerous publications, while the highest urea sigma matrix value was 5.81, and creatinine was 19.02. In the urea sigma matrix, the most widely distributed sigma matrix values was in the range <2 with the interpretation of the results was not acceptable. In the urea matrix, the highest distribution of sigma matrix values was in in the range 6 with world-class quality interpretation. It was concluded that in 15 research data from various journals there were 8 urea sigma matrix data that met the requirements, namely the sigma matrix value. 3 In 27 research data from various journals, there were 23 creatinine sigma matrix data that meet the requirements.
Utilization Dishwashing Soap as a Subtitute of Xylol in the Deparaffinization process of Hematoxylin-Eosin Dye: Review Article: Penggunaan Sabun Pencuci Piring Sebagai Pengganti Xilol Dalam Proses Deparafinasi Perawarnaan Hematoksilin-Eosin mamay, Mamay; Mutmaina, Gina Nafsa; Nurahma, Ina Aflaha
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1629

Abstract

Deparaffinization in the hematoxylin eosin staining process aims to remove paraffin from the tissue, clean the tissue and maximize dye absorption. Utilization xylol as deparaffinization has a drawback, if inhaled too much it will cause harm to the health of the laboratory staff. Considering this, a safer alternative to xylol is needed, one of which is dish washing soap. This study was conducted to determine the use of liquid dish soap at the deparaffinization stage on the quality of tissue staining results. The research method in this research is a literature review study conducted based on sources from several articles published digitally in the Science Direct, Pub Med, NCBI, Researchgate, Google Scholar with the keywords deparafinization, xylene, dish washing soap and Hematoxylin-eosin. Based on the results of a review of ten journals, the concentration of dishwashing soap used was 1.5%, 1.7%, 2% and 2.5% with the most widely used concentration of 1.7%. The most used deparaffinization time with dish soap was 1 minute, one study used 2 minutes. Of the several differences in deparaffinization time and concentration of dish soap, the results adequacy of nuclear and cytoplasmic staining, clarity, uniformity and crispness of staining were very good in almost all studies, there was no difference in quality with the use of xylol. So it can be concluded that the use of dish soap in the deparaffinization process for Hematoxylin staining showed good staining of all tissues. Dish soap can be used as an alternative agent in deparaffinization of Hematoxylin-Eosin staining.
Analysis Corelation Between Work Demands With Stress Labor at Laboratory X Kediri City: Analisis Hubungan Tuntutan Kerja Dengan Perubahan Stres Tenaga Kerja Pada Laboratorium X di Kediri Sumaningrum, Ningsih Dewi
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1630

Abstract

Potential psychosocial hazards are potential hazards caused by the psychological aspects of labor that are not good enough and are not getting enough attention including unsuitable placement of workers, unharmonious and incompatible relationship among individuals in the work organization, work demands, and stress. Excessive work demands not according to ability, target time, concurrent work can cause stress labor. Stress can have bad effect on the safety and health workers. Work stress is a person’s reaction to excessive presure or demands at work detrimental. Purpose This study aims to analyze the correlation between work demands and psychological changes especially stress at laboratory Kediri city. This study design was a quantitative study with a cross sectional approach. Data collection was carried out using quick test questionnaire to detect work stress standardized by the ministry of health. Sampling this study was conducted with a total sampling technique of 14 respondents. The statistical test used was the pearson correlation test. Pearson correlation test results obtained a significance value of 0.046. Thus this value is smaller than 0.05 so it can be concluded that there is significant which means there was a correlation work demands with psychological changes in this case work stress. The company should perform management of work demands, so that the workforce can work comfortably, work productively, and be free from work stress.
Correlation between Corona Viruses Disease (Covid-19) and C-Reactive Protein (CRP) in Patients at Haji Hospital Surabaya: Hubungan Corona Viruses Disease (Covid- 19) Dan C-Reactive Protein (CRP) Pada Pasien Di Rumah Sakit Umum Haji Surabaya Saputro , Tri Ade; Purwaningsih, Nur Vita; Ainutajriani, Ainutajriani; Watoyani , Tony
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 1 (2022): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i1.1631

Abstract

Coronavirus Disease (Covid-19) is a new type of virus that has never been previously identified in humans. Common signs and symptoms of Covid-19 infection include symptoms of acute respiratory distress such as fever, cough and shortness of breath. C-Reactive Protein (CRP) is a protein in serum that causes inflammation in the body. The presence of this inflammatory response causes the levels of CRP in the body to increase significantly. To determine the severity of Covid-19 disease, one of the screening tests used is the CRP examination, starting when clinical symptoms appear, becoming high levels of CRP indicating inflammation or inflammation. This study aims to determine CRP levels in patients who were confirmed positive for Covid-19 at RSU Haji Surabaya. The research method used is descriptive research with secondary data. The sample in the study was 60 patients who had confirmed Covid-19 and performed a CRP test from February to June 2021. The sampling technique used a total sampling technique at the Haji General Hospital Surabaya. The results showed that from 60 confirmed Covid-19 inpatients, 58 patients (96.6%) had CRP levels with high risk criteria or CRP levels > 5 mg/L and 2 patients (3.4%) had CRP levels. with normal criteria or CRP levels < 5 mg/L. Based on the results, it can be concluded that CRP levels are positively correlated with the development and severity of Covid-19 disease.

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