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Borneo Journal Of Pharmascientech
Published by Universitas Borneo Lestari
ISSN : 25413651     EISSN : 25483897     DOI : -
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Borneo Journal of Pharmascientech merupakan jurnal resmi Sekolah Tinggi Ilmu Kesehatan Borneo Lestari. Jurnal memuat naskah hasil penelitian dan artikel review bidang kefarmasian, meliputi farmasi klinik, manajemen & farmasi sosial, farmasi bahan alam, teknologi sediaan farmasi dan lain-lain. Naskah dapat berasal dari mahasiswa, dosen, peneliti, dan lembaga riset.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 178 Documents
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Uji Aktivitas Antibakteri “Ekstrak Metanol Daun Sungkai (Peronema canescens Jack) Terhadap Bakteri Propionibacterium acnes. Shelin Shelin; Fitriyanti Fitriyanti; Muhammad Saufi
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.489

Abstract

The Sungkai plant (P. canescens Jack) is known to have medicinal properties in the traditional treatment of skin diseases. The aim of this research is to identify groups of phytochemical compounds contained in the methanol extract from Sungkai leaves, as well as evaluate the ability of the methanol extract to inhibit the growth of P. acnes bacteria. In the first stage, phytochemical screening was carried out from the methanol extract of Sungkai leaves. The results of this screening show that the methanol extract of Sungkai leaves contains alkaloids, flavonoids, phenols, triterpenoids and tannins. In the antibacterial activity test, the diffusion method with the well technique was used at extract concentrations of 1%, 5%, 10%, 15% and 20%. As a comparison, the positive control used clindamycin with a concentration of 2 µg/disk, while the negative control used Na-CMC with a concentration of 0.5%. The results of the antibacterial activity test showed that at a concentration of 1%, the methanol extract of Sungkai leaves had an inhibition zone with moderate intensity. However, at a concentration of 20% as well as in the positive control clindamycin with a concentration of 2 µg/disc, there was a stronger zone of inhibition. Thus, these findings indicate that methanol extract from Sungkai leaves has the potential to inhibit the growth of P. acnes, which is often associated with skin problems. The phytochemical compounds contained in this extract can be the basis for potential development in natural-based skin
Uji Aktivitas Antibakteri Fraksi N-Heksana Ekstrak Etanol 96% Daun Pare (Momordica charantia L.) Terhadap Bakteri Staphylococcus epidermidis Rabiatul Munawarah; Putri Kartika Sari; Eka Fitri Susiani
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.494

Abstract

Pare leaves (Momordica charantia L.) have many health benefits. Leaves pare (M.chrantia L.) are a trusted herb that is used as an antibacterial plant. N-hexane fraction of pare leaves(S. epidermidis). The purpose of this study is to identify the secondary metabolite compounds found in the n-hexane fraction of ethanol extract 96% of pare leaves (M.charantia L.) and to find out the N-hexane fractions of etanol 96% pare leaves (M.charantia L.) in inhibiting S.epidermidis bacteria. The type of research is experimental. The leaf extraction process uses maseration with 96% ethanol solvent and fraxination using n-hexane solvent. Phytochemical screening tests include flavonoids, alkaloids, saponins, steroids/terpenoids, phenols and tannins. The antibacterial activity carried out using well method with concentration of 1%, 2%, 3% and 4%. The results of this study showed that a fraction of n-hexane ethanol extract 96% of the leaf (M.charantia L.) contained flavonoid, alkaloid and steroid compounds. The n-hexane fraction ethanol extract 96% leaf (M.charantia L.) has antibacterial activity in inhibiting the S.epidermidis bacteria in the weak to strong category. Based on the results, it can be concluded that the fraction n-hexane ethanol extract 96% of the leaf (Momordica charantia L.) is able to inhibit the bacteria S.epidermidis at all concentrations.
Penetapan Kadar Flavonoid Total Ekstrak Etanol 70% Daun Bayam Brazil (Althernanthera sisso) Dengan Metode Spektrofotometri UV-Vis Nur Humaira Marwati; Revita Saputri; Eka Fitri Susiani
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.496

Abstract

Brazilian Spinach (Althernanthera sisso) leaves are known to have a high natural antioxidant activity content of 3.7 ppm. Antioxidants have an important role in the human body to prevent damage caused by free radicals. One of the compounds that have antioxidant activity is flavonoids. Based on this description, it is necessary to know the content of total flavonoids in A. sisso This study aims to determine qualitatively using Thin Layer Chromatography (TLC), while quantitatively using UV-Vis spectrophotometry. Maceration method with 70% ethanol solvent was used to extract Brazilian spinach leaves. Thin Layer Chromatography (TLC) followed by spray reagents was used to test the flavonoid compounds. Quercetin reagent was used to determine total flavonoid levels, while AlCl3 was used to determine total flavonoid levels. The results of this qualitative test showed the presence of flavonoids, and in the quantitative test using UV-Vis spectrophotometry the total levels of flavonoids were 70.890 ± 1.723% w/w quercetin equivalent. The 70% ethanol extract of A. sisso leaves contains flavonoids so that it has the potential to be developed as a medicinal plant
Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di RS “X” Kabupaten Tanah Bumbu Alpia Damayanti; Nur Mahdi; Andi Sultang
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.498

Abstract

Diabetes mellitus is a disease with the highest proportion in developing countries. Poor quality of life can affect the disease. This study aims to analyze the quality of life based on the characteristics of type 2 DM patients at one of the Tanah Bumbu district hospitals. The research method used was a quantitative method using a cross-sectional design with convenience sampling technique and using a DQOL questionnaire based on patient characteristics, namely age, sex, education, occupation, marital status and length of illness. This study used Chi Square statistical software analysis with a significance level of p value > 0.05. The data sample is 84 respondents. The results of this study showed that the quality of life of DM patients was in the high category as much as 79.8%, 16.7% in the medium category and 3.6% in the low category. Based on the results of this study where the p value > 0.05 on quality of life based on patient characteristics there is no significant relationship between characteristics and quality of life.
Uji Aktivitas Antibakteri Ekstrak Etanol 70% Daun Ginseng Jawa (Talinum paniculatum (Jacq.) Gaertn) Terhadap Bakteri Shigella dysenteriae Riwanda Oktaviani; Fitriyanti Fitriyanti; Putri Kartika Sari
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.502

Abstract

Shigellosis is a digestive tract infection that can be caused by S dysenteriae bacteria. Javanese ginseng (T. paniculatum (Jacq.) Gaertner) is a plant known to have antibacterial potential. This study aims to determine the content of the class of compounds contained in the 76% ethanol extract of Javanese ginseng leaves and to observe the antibacterial activity of the 70% ethanol extract of Javanese ginseng leaves against S. dysenteriae based on the diameter of the inhibition zone. Antibacterial testing using the disc diffusion method with six variations of extract concentrations including 5%, 10%, 20%, 40%, 60% and 80% for positive and negative controls used Azithromycin 15µg/disk and 0.5% Na-CMC. Identification of the content of secondary metabolites was carried out on alkaloids, phenols, flavonoids, quinones, saponins, steroids/triterpenoids and tannins. The results of the screening test for 70% ethanol extract of Javanese ginseng leaves contained flavonoids, phenols, saponins, steroids and tannins. Antibacterial testing at the smallest concentration, namely 5% of the inhibition zone, is considered weak with an average inhibition diameter of 4.01 mm and at the largest concentration, namely 10%, the inhibition zone is considered strong with an average inhibition zone diameter of 11.26 mm.
Pengaruh Pemberian Leaflet Terhadap Tingkat Kepatuhan Minum Obat pada Pasien Diabetes Melitus Tipe-2 di Puskesmas Guntung Manggis Siti Khadijah; Helmina Wati; Aristha Novyra Putri
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.508

Abstract

Type 2 diabetes mellitus is a metabolic disorder characterized by increased blood glucose levels (hyperglycemia) due to decreased insulin secretion by pancreatic beta cells or impaired insulin function. Compliance with taking medication is very important to achieve therapeutic success and prevent complications by providing education using leaflets so as to increase understanding of treatment instructions. The purpose of this study was to determine the effect of giving leaflets on the level of medication adherence and blood glucose levels during (BGLD) in patients with type-2 diabetes mellitus at the Guntung Manggis Health Center. This study used a quasi-experimental design method with a pretest-posttest duo grub approach using the MMAS-8 questionnaire. Sampling was taken prospectively with a total of 88 patients divided into 2 intervention and control groups. There were differences in the level of adherence to taking medication before being given the leaflet as many as 26 respondents were in the adherent category and increased to 43 respondents after being given the leaflet. The results of the study obtained an average value of BGLD before being given a leaflet of 281 mg/dL and after being given a leaflet of 262 mg/dL. The statistical test results showed that there was an effect of giving leaflets on adherence to taking medication in patients with type-2 DM at the Guntung Manggis Health Center with a p-value of 0.001 <0.05 and a BLD value of 0.000 <0.05
HUBUNGAN ANTARA PENGETAHUAN DAN PERILAKU TERKAIT DIABETES MODIFIABLE RISK FACTORS PADA PASIEN DM PUSKESMAS SUNGAI BESAR BANJARBARU Karunita Astuti; Vita Rahmawati; Ika Maulida Nurrahma
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.510

Abstract

Diabetes mellitus disebabkan oleh peningkatan kadar gula darah akibat kekurangan insulin. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan dan perilaku terkait diabetes Modifiable Risk Factors pada pasien DM Puskesmas Sungai Banjarbaru. Penelitian ini merupakan penelitian observasional deskriptif dengan pendekatan cross sectional menggunakan kuesioner yang dilaksanakan di Puskesmas Sungai Besar Banjarbaru periode februari-april 2019. Diperoleh data sebanyak 108 sampel yang memenuhi kriteria inklusi yakni pasien yang terdiagnosa diabetes, usia produktif (18-64 tahun) dan pasien yang baru melakukan terapi. Hasil penelitian ini adalah tingkat pengetahuan tertinggi pada kategori baik (89,8%) dan pada tingkat perilaku yang paling tinggi pada kategori baik (69,4%). Diperoleh nilai signifikansi 0,214 sehingga dapat disimpulkan tidak ada hubungan antara pengetahuan dan perilaku terkait diabetes modifiable risk factors pada pasien DM Puskesmas Sungai Besar Banjarbaru.
Tingkat Kepuasan Pasien Terhadap Pelayanan Informasi Obat di Puskesmas Tamalanrea Jaya Andi Nurpati Panaungi; Suci Aulia
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.511

Abstract

Understanding patient needs and desires is something that influences satisfaction. To create patient satisfaction, the Community Health Center must create and manage a system to obtain more patients and the ability to retain patients. Drug Information Services (PIO) is an obligation that must be provided by pharmaceutical personnel related to the use of medicines handed over to patients and the use of medicines appropriately, safely and rationally at the request of the public. The aim of this research is to determine the level of patient satisfaction with drug information services at the Tamalanrea Jaya Health Center, Makassar City. The type of research used is non-experimental research with a descriptive research design using quantitative analysis, namely using in-depth data analysis using a questionnaire as an instrument. research. The sample from this research was calculated using the Slovin formula which resulted in 74 samples. Based on the analysis of data obtained from research conducted on 74 respondents, the conclusion was that the level of satisfaction in the dimension of physical evidence (tangibles) was dominated by those who were satisfied, namely 73, 0%, the reliability dimension is dominated by those who are satisfied, namely around 71.6%, the responsiveness dimension is dominated by those who are satisfied, namely 73.0%, the assurance dimension is dominated by those who are satisfied, namely 67, 6%, while the empathy dimension is dominated by those who are satisfied, namely 60.8%.
PENGARUH LEAFLET TERHADAP KEPATUHAN MINUM OBAT PADA PASIEN HIPERTENSI DI PUSKESMAS MARTAPURA 1 Esty Restiana Rusida; Siti Hamdah; Cast Torizellia
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.514

Abstract

The high mortality caused by hypertension continues to increase every year, this is due to the absence of symptoms that arise. A person develops hypertension if blood pressure exceeds 140/90 mmHg. One of the treatments for hypertension is adherence to treatment, because compliance is one of the keys to the success of therapy. Treatment adherence can be improved by being given leaflets. The purpose of this study was to determine the effect of leaflets and the level of compliance of hypertensive patients at the Martapura 1 Health Center. This research method is pre-experimental with One Group Pretest and Posttest Design design. The total sample in this study was 220 respondents. Sampling by filling out the Morisky Medication Adherence Scale-8 questionnaire. Based on the pretest results, high compliance was 23 people (10.5%), medium compliance was 66 people (30.0%), and low compliance was 131 people (59.5%). The posttest results obtained high compliance of 120 people (54.5%), medium compliance of 90 people (40.9%), and low compliance of 10 people (4.5%). Data analysis using the McNemar test showed a significant effect with p-value = 0.000 (p<0.05), so it can be concluded that there is an effect of giving medication adherence leaflets at the Martapura 1 Health Center.
Penelusuran Fraksi Aktif Senyawa Yang Berpotensi Sebagai Antioksidan Dari Daun Tanaman Sterculia macrophylla Vent. Prastiwi, Rini; Nabila, Sausan; Diana, Popi; Nabila, Helvi Airin; Agistananda, Banna
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.515

Abstract

Ventilasi Sterculia macrophylla. merupakan salah satu tanaman yang mempunyai aktivitas antioksidan. Komponen utama dari genus Sterculia adalah fenol dan flavonoid. Tujuan penelitian ini adalah untuk mengetahui fraksi ekstrak metanol daun Sterculia macrophylla Vent. manakah yang mempunyai aktivitas antioksidan dan nilai IC50 aktivitas antioksidan pada fraksi ekstrak metanol Sterculia macrophylla Vent. daun-daun. Simplisia diekstraksi secara bertahap dengan pelarut n-heksana, etil asetat dan metanol. Ekstrak yang paling aktif adalah ekstrak metanol. Ekstrak metanol ini difraksinasi menggunakan kromatografi kolom, hasil fraksi tersebut kemudian dikelompokkan dan selanjutnya dianalisis senyawa yang berpotensi memiliki aktivitas antioksidan pada fraksi tersebut menggunakan KLT Bioautografi, dan ditentukan aktivitas antioksidannya dengan metode DPPH. Pada metode DPPH diperoleh nilai IC50 fraksi terbaik yaitu pada fraksi 3 dengan nilai IC50 sebesar 87,67 μg/ml dan fraksi 4 dengan nilai IC50 sebesar 77,40 μg/ml, sedangkan pada F3.3 nilai IC50 sebesar 173,21 μg /ml diperoleh. Hal ini menunjukkan nilai IC50 fraksi tersebut lebih tinggi dibandingkan querstin yang mempunyai nilai IC50 sebesar 4,19 μg/ml. Kandungan total fenol pada kelompok fraksi daun Sterculia macrophylla Vent. pada F1 sebanyak 45,253 mgGAE/g, pada F2 diperoleh sebanyak 59,668 mgGAE/g dan pada F3 diperoleh sebanyak 71,605 mgGAE/g. Fraksi flavonoid total ekstrak metanol daun Sterculia macrophylla pada F1 memperoleh hasil sebesar 9,8945 mgQE/g sampel, F2 memperoleh hasil sebesar 6,4042 mgQE/g sampel, F3 memperoleh hasil sebesar 6,6883 mgQE/g sampel.

Page 13 of 18 | Total Record : 178

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