cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Mesran
Contact Email
mesran.skom.mkom@gmail.com
Phone
+6282370070808
Journal Mail Official
mesran.skom.mkom@gmail.com
Editorial Address
Jalan sisingamangaraja No 338 Medan, Indonesia
Location
Kota medan,
Sumatera utara
INDONESIA
Journal of Pharmaceutical and Health Research
Published by Forum Kerjasama Pendidikan TInggi
ISSN : -     EISSN : 27210715     DOI : https://doi.org/10.47065/jharma.v3i1.1322
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Health Research memiliki bidang kajian, yaitu: 1. Bidang Gizi Klinis 2. Bidang Gizi Masyarakat 3. Pangan dan Gizi 4. Inovasi Pangan 5. Hematologi 6. Parasitologi 7. Biokimia 8. Laboratorium Kesehatan 9. Teknologi Laboratorium 10. Farmakologi 11. Farmasi 12. Keperawatan Jiwa 13. Keperawatan Anak 14. Keperawatan Maternitas 15. Keperawatan Medikal Bedah 16. Keperawatan Keluarga 17. Keperawatan Komunitas 18. Kesehatan Masyarakat 19. Teknologi Kesehatan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 9 Documents
 1 
Search results for , issue "Vol 5 No 2 (2024): June 2024" : 9 Documents clear
Uji Aktivitas Antioksidan Fraksi Ekstrak Kulit Bawang Putih (Allium Sativum L.) dengan Metode FRAP (Ferri Reducing Antioxid Power) Pratiwi, Rizky Indah; Kalsum, Ummu; Suleman, Abdul Wahid
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.4166

Abstract

Garlic is used by some people to treat itching on the skin which is often known as tinea versicolor. These materials are used by rubbing the itchy skin area. Garlic produces waste in the form of skin, garlic bulb skin contains flavonoids, phenols, alkaloids, tannins and saponins, which have antioxidant activity. This study aims to determine the antioxidant activity of the garlic skin extract fraction (Allium Sativum L.) using the FRAP (Ferric Reducing Antioxidant Power) method and to determine the IC50 value of the garlic skin extract fraction using the FRAP method. The type of research used was experimentation with garlic skin samples extracted using the maceration method with 70% ethanol solvent, then fractions were carried out with polar (ethanol:water) and non-polar (n-hexane) solvents. Antioxidant activity testing using uv-vis spectrophotometry. Based on the results of the descriptive analysis, it showed that the garlic extract and skin fraction samples had antioxidant activity. The results obtained were the ethanol:water fraction was 1.52 ppm and the n-hexane fraction was 2.75. conclution is the polar fraction (ethanol:water) and the non-polar fraction (n-hexane) have strong antioxidant activity.
Perbandingan Aktivitas Antioksidan Ekstrak Biji Mangga Arumanis (Mangifera indica L.) Segar dan Kering dengan Metode DPPH (1,1 Diphenyl-2-picrylhidrazyl) Ifmaily, Ifmaily; Juli Fendri, Sandra Tri; Husyalam, Mifta; Rahmawati, Annisa
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.4669

Abstract

In previous research, the arumanis mango plant was proven to have antioxidant properties, because it contains secondary metabolites of flavonoids and tannins. Based on this research, arumanis mango seeds also contain flavonoids and have the potential to act as antioxidants. Arumanis mango seeds are a form of organic waste that is often thrown away after we eat arumanis mango fruit and have the potential to be used as a basic ingredient for making antioxidant products. The aim of this research was to determine the antioxidant activity and compare the antioxidant of fresh and dried arumanis mango seed extract samples using the DPPH (1,1-diphenyl-2-picryhydrazyl) method. The results obtained from the maximum absorption wavelength of DPPH are 518 nm, with an absorbance of 0.647. The results of comparative antioxidant activity for gallic acid obtained IC50 = 2.8997 µg/mL, and a sample of fresh arumanis mango seed extract with an IC50 value = 20.4806 µg/mL, and dried mango seed extract IC50 = 21.1501 µg/mL. Based on the research results obtained, the antioxidant activity of fresh and dried arumanis mango seed extract samples was classified as very strong (<50 µg/mL). The antioxidant activity of fresh extracted seed samples was higher than that of dried arumanis mango seed samples, because if IC50 higher, its mean antioxidant activity is lower.
Uji Efektivitas Analgetik Ekstrak Etanol Buah Kundur (Benincasa hispida (Thunb.) Cogn.) Terhadap Tikus Putih Jantan (Rattus norvegicus L.) yang Diinduksi Asam Asetat Gunawan, Muhammad; Fatimah, Cut; Santika, Dewi
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.5015

Abstract

The class of drugs known as analgesics work by reducing or inhibiting pain. This can be achieved in several ways, such as by preventing the synthesis of prostaglandins, which are mediators of pain perception, or by reducing the sensitivity of pain receptors to mechanical, thermal, electrical stimuli. Interest in using natural-based medicine for therapy is increasing in Indonesian society. Kundur fruit is one of the medicinal plants that can be used as an analgesic. It has been empirically proven that kundur fruit (Benincasa hispida (Thunb.) Cogn.) can reduce pain. The purpose of this study was to ensure that the preparation of simplisia, macroscopic and microscopic analysis, phytochemical screening of simplisia, and analgesic efficacy tests were carried out experimentally in this study. Acetic acid 0.5% was injected intraperitoneally under the abdomen of male white rats to stimulate the male white rats. oral administration of ethanol extract solution of kundur fruit at doses of 100 mg/kgBB, 200 mg/kgBB, 400 mg/kgBB, CMC 0.5% (blank) and metampirone 45 mg/kgBB For one hour the number of writhing animals was counted every ten minutes. In addition, the collected data were statistically examined using Tukey test and SPSS ver. 20 One Way ANOVA. Analysis of simplisia and ethanol extracts of kundur fruit had phytochemical screening for the presence of alkaloids, flavonoids, tannins, saponins, steroids and glycosides. The percentage of writhing reduction increased with increasing doses of bamboo randu herb decoction, indicating an increase in analgesic potential and efficacy. Based on the results of the Tukey test and One Way ANOVA test, a dose of 400 mg/kgBB has the best analgesic potential at the 50th minute and is not statistically different from metampirone 45 mg/kgBB.
Potensi Buah Rimbang (Solanum torvum Sw.) sebagai Analgetik dengan Metode Induksi Asam Asetat dan plantar test Utami, Dinda Sari; Nasution, Melvi Ariati; Fauzi, Ziza Putri Aisyia; Sari, Syilvi Rinda; Hartini, Putri Tri; Rawitri, Kiki
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.5057

Abstract

Abstract is Solanum torvum is a traditional medicine plant ingredient for treating stomach disease, relieving pain (analgesic), initiating blood circulation, removing cough (anti-tussing) and anti-inflammatory. At this examination, a phytochemical screening of powder and fruit extracts has been carried out. Simplicity characteristic tests and analgesic effect tests with acetate acid induction method and plantar tests with suspensions of ethanol extract are given in doses of 500, 1000 and 2000 mg/kgBB, metampiron suspense 2% positive ontrol, CMC suspense 0.5% as negative control as well as gland data are analyzed with ANOVA method. Results of screening of phytomia powder and ethanole extract contains secondary metabolite compounds of the classes of alkaloids, tannins, saponins, flavonoids, steoids and glycosides. Characteristic results of simplisia powder are 8% water content, 5.3% total ash content, 29.6% water-soluble sulphur content, 18.9% ethanol-solubility, 0.48% acid-insoluble ash content. Ethanol extract with 2000 mg/kgBB acetate acid induction method has the highest analgesic strength and effectiveness percentage of 55.9% and 86.04% for plantar test methods with hight analgetic values with 29,3±1,7 second.
The Effect of Providing Tomato Juice on the Hemoglobin Concentration of Pregnant Women Hatima, Husnul; Hafsah, Hafsah; Sulistyowati, Endang
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.5171

Abstract

Pregnant women are a vulnerable group prone to malnutrition-induced anemia. In 2023, Puskesmas Tamamaung reported a staggering 73.9% prevalence of anemia among pregnant women. Anemia in pregnancy poses risks such as maternal mortality, miscarriage, intrauterine growth retardation, and postpartum hemorrhage. To address this, tomato juice, rich in vitamin C crucial for iron absorption, is proposed as a potential solution to enhance hemoglobin levels.The objective of this quasi-experimental study is to assess the efficacy of tomato juice supplementation in increasing hemoglobin (Hb) levels among pregnant women diagnosed with anemia. A quasi-experimental study utilizing a pre-test post-test non-equivalent control group design was conducted. The study population comprised 28 second and third-trimester pregnant women with anemia registered at Puskesmas Tamamaung from February to March 2024. All 28 participants were included as the total sample. Data were collected using observation sheets and hemoglobin measurement tools. Paired t-tests and independent t-tests were employed for data analysis.Significant differences were observed in hemoglobin levels before and after tomato juice consumption among pregnant women at Puskesmas Tamamaung. Tomato juice supplementation was found to be more effective in increasing hemoglobin levels compared to iron tablet supplementation alone.Tomato juice facilitates hemoglobin synthesis by expediting the process from erythroblasts to normoblasts and reticulocytes, thereby accelerating hemoglobin formation.The administration of tomato juice effectively increases hemoglobin levels among pregnant women with anemia. This underscores the potential of tomato juice as a supplementary intervention in combating maternal anemia during pregnancy.
Boosting Hemoglobin: The Power of Dates and Honey for Third Trimester Pregnant Women Nurseha, Nurseha; Utami Subagio, Sri; Arifiati, Nurce; Suwardiman, Deni
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.5186

Abstract

Anemia poses a significant health challenge, particularly among pregnant women, with Indonesia facing a notable burden in maternal mortality rates (MMR). This study investigates the efficacy of date fruit and honey supplementation in addressing anemia among third-trimester pregnant women attending Kramatwatu Community Health Center. Drawing on a quantitative approach with a quasi-experimental design, the research aims to elucidate the impact of this intervention on hemoglobin (HB) levels. The prevalence of anemia among pregnant women is alarming, with all respondents in the study experiencing anemia before the intervention. However, following the provision of date fruit and honey, a substantial increase in HB levels was observed, indicating a promising avenue for improving maternal health outcomes. Utilizing SPSS for analysis, univariate and bivariate analyses were conducted to describe variables and test intervention effects. The study underscores the potential effectiveness of date fruit and honey supplementation in ameliorating anemia among pregnant women, although further research is warranted to ascertain long-term efficacy and optimal dosages. Comprehensive interventions addressing nutritional deficiencies and healthcare access are crucial for advancing maternal health goals and reducing MMR in Indonesia.
Boosting Infant Growth: Exploring the Influence of Baby Massage on Weight Gain in 1-6 Month-Olds Lailaturohmah, Lailaturohmah; Soya Nita, Elin; Merita Sari, Pety
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.5246

Abstract

Massage therapy is one of the oldest healing methods worldwide, encompassing both healthcare and treatment. Baby massage offers numerous benefits, including the enhancement of infant weight gain. In Kediri, East Java, child growth and development issues persist, with a prevalence of underweight children at 17.5% and wasted children at 9.0%. This research aims to analyze the impact of baby massage classes on infant weight gain. This study adopts a quasi-experimental design with a Two Group Pretest-Posttest format. The research subjects were divided into two groups: control and treatment. Pretest and posttest measurements were conducted. Statistical analysis using paired t-tests yielded a significance level of p=0.000 (p<0.05), indicating a significant influence of baby massage classes on weight gain in infants aged 1-6 months. The average weight gain after intervention was 5200 grams.Of the total respondents, 19 infants (63.3%) experienced weight gain, with 13 from the intervention group and 6 from the control group. However, 9 infants (30%) maintained their weight, with 2 from the intervention group and 7 from the control group, while 2 infants (6.7%) experienced weight loss, all from the control group.Baby massage classes have a positive impact on infant weight gain at the Ibu Hawa Clinic in Kediri Regency.
Sabun Cair Antiseptik Sari Air Kulit Buah Salak (Salacca zalacca) Gunawan, Muhammad; Fatimah, Cut; Panjaitan, Sariatmaja
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.5327

Abstract

In addition to removing dirt that sticks to the skin, skin wash soap also functions as an antiseptic to ward off skin diseases caused by germs, many antiseptic soaps on the market contain synthetic antibacterials but often have negative side effects. Therefore, it is important to make soap with natural ingredients. For example, salak (Salacca zalacca) fruit peel contains saponin and polyphenol compounds that are antibacterial. To test the antibacterial activity and make liquid soap containing salak fruit peel juice as a cleanser and antibacterial, this study conducted phytochemical screening on salak fruit peel. The research stages include, phytochemical screening of salak fruit peel, liquid soap formulation with 10%, 20%, and 30% salak fruit peel juice (SKBS), liquid soap assessment related to stability, foam height, pH, irritation, and liking test. Antibacterial activity test against germs from volunteer hand wash water specimens against Escherichia coli, and Staphylococcus aureus bacteria. The results showed that salak fruit peel juice can be used to make liquid soap that meets physical quality standards because it contains alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and glycosides. The strongest antibacterial activity with inhibition diameters against Staphylococcus aureus (18.63 ± 0.33) mm and Escherichia coli (16.17 ± 0.33) mm) made 20% SKBS liquid soap the best choice, which was determined by the results of the study.
Uji Sitotoksisitas Ekstrak Etanol Daun Bayam Duri (Amaranthus spinosus L.) dengan Metode Brine Shrimp Lethality Test (BSLT) Fauzi, Ziza Putri Aisyia; Ridwanto, Ridwanto; Rani, Zulmai; Arifin, Khairil Fikri
Journal of Pharmaceutical and Health Research Vol 5 No 2 (2024): June 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i2.5398

Abstract

Free radicals can cause chronic disease, it takes years for the disease to become real or accumulative. One possibility that can occur as a result of the work of free radicals such as cancer. Cancer is one of the non-communicable diseases that is a public health problem, both in the world and in Indonesia. One of the plants that has the potential as an anticancer is Amaranthus spinosus L. The results showed that thorn spinach leaves contain strong antioxidants. This study aims to determine the class of secondary metabolites contained in the ethanolic extract of thorn spinach leaves and the cytotoxicity of the ethanolic extract of A.spinosus by looking at the LC50 value which was tested using the Brine Shrimp Lethality Test (BSLT) method. This research includes phytochemical screening of A.spinosus extract and Brine Shrimp Lethality Test (BSLT) method by looking at the number of larvae mortality of Artemia salina leach (LC50). The results of the phytochemical screening test showed that A.spinosus were positive for flavonoids, alkaloids, saponins, tannins, steroids and glycosides. The results of the cytotoxicity test using probit analysis showed an LC50 value of 269.15 g/mL, so it can be concluded that the ethanolic extract of A.spinosus is toxic and has potential as an anticancer.

Page 1 of 1 | Total Record : 9

 1 

Filter by Year

2024 2024


Reset
Filter By Issues
All Issue Vol 6 No 3 (2025): October 2025 Vol 6 No 2 (2025): June 2025 Vol 6 No 1 (2025): February 2025 Vol 5 No 3 (2024): October 2024 Vol 5 No 2 (2024): June 2024 Vol 5 No 1 (2024): February 2024 Vol 4 No 3 (2023): October 2023 Vol 4 No 2 (2023): June 2023 Vol 4 No 1 (2023): February 2023 Vol 3 No 3 (2022): October 2022 Vol 3 No 2 (2022): June 2022 Vol 3 No 1 (2022): February 2022 Vol 2 No 3 (2021): Oktober 2021 Vol 2 No 2 (2021): Juni 2021 Vol 2 No 1 (2021): Februari 2021 Vol 1 No 3 (2020): Oktober 2020 Vol 1 No 2 (2020): Juni 2020 Vol 1 No 1 (2020): Februari 2020 More Issue