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INDONESIA
Articles 1,077 Documents
Toxic Effect Of The Compound {1,3 Bis (P-Hydroxyphenyl) Urea} On Triiodothyronine (T3) Hormone Levels In Pregnant White Rats (Rattus Norvegicus L.) Putri Aisyia Fauzi, Ziza; Harahap, Urip; Yuandani, Yuandani; Berkat Waruwu, Syukur; Purnomo, Hari; Satria, Denny
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.719

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed drugs for pregnant women to treat fever, pain and inflammation. Specific NSAIDs can displace thyroid hormone from its protein binding sites, causing thyroid hormone measurement problems. {1,3 bis (p-Hydroxyphenyl)urea} is a modified p-aminophenol compound with potent analgesic and anti-inflammatory activity and less toxicity. This study is a follow-up to previous research to observe the toxic effect on triiodothyronine hormone levels after administration of {1,3 bis(p-Hydroxyphenyl)urea} compound in pregnant white rats. The toxic effect test was carried out by giving the test preparation to pregnant rats, which had been divided into five groups, namely the normal control group (CMC-Na 0.5%), the positive control (Gabapentin 50 mg/kg BW), Compound {1.3 bis (p- Hydroxyphenyl)urea} at a dose of 50 mg/kg BW, 500 mg/kg BW and 1000 mg/kg BW. Mice were given the test preparation every day from the 6th to the 15th day of pregnancy. Blood was taken on the 16th day, and T3 hormone levels were measured using the ELISA method. The results showed that the T3 hormone levels in the {1,3 bis(p-Hydroxyphenyl)urea group had no significant difference from the normal control group, so it was concluded that {1,3 bis(p-Hydroxyphenyl)urea) did not have a significant effect on the hormone T3.
Soybean Supply Response Model In Sub-Optimal Land In Tanjab Timur District: Application Of The Meta Response Function Edison, Edison
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.720

Abstract

Soybean production in the Tanjab Timur region has been on a downward trend for nearly a decade. This requires attention and assessment to find solutions to existing problems. The objective of study is to (1)evaluate the use of inputs and their effect on production, as well as investigate the capacity of production factors, such as landand other factors to analyze supply responses; and (2) analyze soybeansupply response variable to the components of input costs, gross revenue, and other variables, to produce a soybean supply response model in sub-optimal land types: Application of Meta-Response Functions. This research was conducted in 2021 on peatland types (sub-optimal). Stratified random sampling is used for the land area.Appropriate qualitative and quantitative data analysis methods are used, called the Meta Response Function, which in their application is distinguished from the research objectives, namely in the first objective using the Production Function Empirical Model, and in the second using the Meta-Response Model. The results showed that soybean farmers on peatland in the research area respond to changes in input use efficiently. In terms of output supply, it responds to soybean production. In terms of input demand, many variables aresensitive to the use of labor, maintenance, and harvesting labor. Production elasticity completes the policy section of the database foranalysis of the policy impact of applying alternative inputs on soybeansupply and input demand.
Development Of Risk-Based Audit Method Standard For Stadium Project Using Design And Build Contract To Minimize Dispute Based On Inspectorate Perpective Ferdinand, Joshua; Putro, Anggoro; Latief, Yusuf
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.721

Abstract

Construction projects have been developing from the management side year by year. One of the problems that government has been facing government construction projects over the years is the duration of the procurement process that takes too long which is hard to be implemented if the project is urgent in terms of time. This creates the urgency to seek the solutions to the problem of how to shorten the time of the procurement process. The design and build integrated contract method that unites the planning and implementation process simultaneously is able to answer these problems and shorten the procurement time of government construction projects. However, there are many disputes faced by construction projects that use integrated design contracts postproject, one of which comes from the Government Internal Supervisory Apparatus (APIP) or commonly called the Inspectorate. This is because there are several different standard between the inspectorate and the owner or contractor that has been used in the process of government construction projects Audit. This study aims to identify the standards of the audit process of the Inspectorate, analyze the risks that cause disputes, and to develop standards for risk-based audit methods for design and build-based construction projects in order to minimize disputes that occured from the inspectorate side of perspective.
Uncovering The Relationships Between Strategic Capability, Strategic Flexibility, And Performance Evanthi, Ayundha; Azhar, Ratih Mukti
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.722

Abstract

Abstract. Strategic flexibility and strategic capability are seen as strategic activities carried out by companies to compete and adapt to the business environment to achieve the expected performance. The objectives of this research are: (1) examine strategic flexibility, strategic capability, and performance by emphasizing their relationships, dimensions and roles of context (2) identify the relationship between strategic flexibility, strategic capability and performance that can be used for future theory development. This research uses bibliometric analysis to map how strategic flexibility, strategic capability and performance intended from several previous journals using VOSviewer. This research concludes that implementing strategic flexibility and strategic capability will result in effective relationships and good firm performance although strategic flexibility is not directly related to the strategic capability. Performance mediates the influence between strategic flexibility and strategic capability. The strategic flexibility is influenced by product innovation, absorptive capacity, and dynamic capability, in the other hand, strategic capability is influenced by network capability. The implication of this research are following researches can add literatures and new theories on the strategic flexibility and strategic capability so that research and discussion on this object can continue to grow. Keywords: Strategic Flexibility, Strategic Capability, Performance
Growth, Intellectual Capital, Financial Performance And Firm Value : Evidence From Indonesia Automotive Firms Johanda Putri, Indah Ayu; Budiyanto, Budiyanto; Triyonowati, Triyonowati; Ilham, Ilham
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.723

Abstract

This study analyzes and explains empirical evidence of the effect of growth and Intellectual Capital respectively on financial performance and firm value, as well as the role of Financial Performance in mediating the influence of company growth and Intellectual Capital respectively on firm value. The benefits of this research are expected to be a reference that enriches the literature of Management Science, especially related to signaling theory and Resource Based Theory. In addition, this research is expected to provide benefits for automotive company managers in developing strategies that can improve financial performance and firm value, investors in automotive companies in making the right decisions in investing in automotive companies and the government in formulating policies related to automotive companies so that more investors invest in automotive companies. To test the hypothesis used Partial Least Square (PLS) analysis. The results of the hypothesis test show that: (1) the company's growth has a positive and insignificant effect on financial performance, (2) Intellectual Capital has a positive and significant effect on financial performance, (3) company growth has a positive and insignificant effect on firm value, (4) Intellectual Capital has a positive and insignificant effect on firm value, (5) financial performance has a positive and significant effect on firm value, (6) financial performance does not mediate the company's growth to the company's value and (7) financial performance mediates Intellectual Capital to the value of the company
Maximal Flow of Transportation Network in Medan City Using Ford-Fulkerson Algorithm Marpaung, Faridawaty; Arnita, Arnita; Sari, Nila
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.724

Abstract

Transportation is a major component of living, government, and social systems. Tsocio-demographic conditions influence the performance. In this study has a purpose as an investigation of an event that measures the maximal capacity of the road as a way to overcome congestion. Searching for the maximal flow based upon the graph formed using the Ford-Fulkerson Algorithm with numerous stages, namely determining the possible pathway through the source point to the main point arranged in numerous iterations by analyzing the graph formed. Then the initialization process is given by zero flow from each side of the graph, then the search for maximal flow is obtained after doing as many as 16 iterations. The residual flow results from subtracting the total number of flows by the number of flows at each iteration. The iteration will stop if no more augmenting pathway is found. Cuts will occur if the amount of flow equals the amount of capacity. Research data is in the form of public transportations in Medan and routes. The data was obtained directly from the archives of the Transportation Service in Medan City. The search for the maximal flow of the transportation network is carried out by observing the public transportation route in the city of Medan, namely the public transportation route through Jalan Jamin Ginting to Jl. Various types of public transportation traverse Williem Iskandar. Based upon the research, the maximal capacity can be exceeded through the transportation network. There are 5 types of public transportations. The pathway through City Hall - Jl. Putri Hijau and the pathway through Jl. Perintis Kemerdekaan–Jl. HM. Yamin has exceeded capacity because the types of public transportation that pass through the two roads are 15 and 9. However, the other lanes are still low, so it should divert some types of public transportation overload to empty roads.
Characterization, Phytochemical Screening of Phyllanthus emblica L. Fruit Nanoherbal and Determination of the Estrus Cycle of Female Rats Nurul Suci; Masfria; Aminah Dalimunthe; Hafid Syahputra
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.727

Abstract

One of a plant that is thought to have quite high antioxidant activity is kemloko (Phyllanthus emblica L.). This plant is a material that is often used by the community as a traditional medicine. This plant in India has been used to treat cancer, diabetes, liver (liver), heart problems and anemia. This biological activity is thought to be caused by the presence of bioactive compounds from secondary metabolites contained therein, especially compounds from the phenolic and flavonoid groups. The short length of the estrus cycle of rats makes them ideal for investigation of changes occurring during the reproductive cycle. The estrus cycle lasts four days and is characterized as: proestrus, estrus, metestrus and diestrus, which may be determined according to the cell types observed in the vaginal smear. Since the collection of vaginal secretion and the use of stained material generally takes some time, the aim of the present work was to provide researchers with some helpful considerations about the determination of the rat estrus cycle phases in a fast and practical way. This study began with macroscopic examination, examination of water content, examination of water-soluble extract levels, examination of ethanol-soluble extracts, examination of total ash content, and also an examination of acid-insoluble ash levels, phytochemical screening of Phyllanthus emblica L. fruit nanoherbal and determination of the estrus cycle of female rats. The results of phytochemical screening showed that the compound of Phyllanthus emblica L. Fruit nanoherbal contained a class of secondary metabolites of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and glycosides. And the estrus cycle of female rats can be determined by observing changes in vaginal epithelial cells.
Estimation Of Greenhouse Gas Emissions At Gunung Kupang Final Processing Site Landfill Using The IPCC Method Yulianto, Khenza Atthaya Namira; Abrar Firdausy, Muhammad; Riduan, Rony; Puteri Mahyudin, Rizqi
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.729

Abstract

Methane gas (CH4) is one of the main Greenhouse Gases (GHG), which contributes 14.5% to global warming. The methane gas potential that can be created from final processing site landfills in 45 big cities in Indonesia in 2010 reached 11,390 tons of CH4/year or the equivalent of 239,199 tons of CO2/year. The decomposition process that occurs in the waste pile will produce methane emissions and be released into the atmosphere by 50-60%. Gunung Kupang final processing site is a final processing site that serves the Banjarbaru City area in addition to the Banjarbakula Regional final processing site, with waste coming in every day which continues to increase and has the potential to generate emissions. The purpose of this research is to analyze the characteristics in the form of waste generation and composition at the Gunung Kupang final processing site and to analyze the estimation of methane gas from the Gunung Kupang final processing site landfill activities using IPCC methods. The methods used in this study are the Intergovernmental Panel on Climate Change (IPCC). Total greenhouse gas emissions produced in the IPCC method from 2014-2020 were 1.49 Gg/year. In 2021-2024, it is estimated that methane produced using the IPCC method is 0.528 Gg/year
Isolation of Chitosan From Dogol Shrimp Skin (Parapenaeopsis sculptilis) Anggreini, Dea; Yuandani, Yuandani; Sinaga, Siti Morin
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.737

Abstract

In Indonesia, shrimp underwent a "cold storage" process where the heads, tails, and shells were discarded as waste. This shrimp waste could pollute the environment around the factory so it needed to be utilized. So far, shrimp shells had only been used as ingredients for making crackers, shrimp paste, and animal feed supplements. The remaining shrimp shells that had been separated were made into chitosan which was then subjected to characterization tests. The three steps of the chitosan isolation process were deproteinization, demineralization, and deacetylation. The analytical tests carried out were testing the water content, ash content, and functional groups contained in chitosan which were identified using the Fourier Transform Infra Red (FT-IR) Spectrophotometer. Based on the test results, there was a moisture content of 9.27% ??and an ash content of 1.69% in the chitosan samples made from shrimp shells. Functional groups of shrimp shell chitosan were identified using FT-IR characteristics. The -NH- group, which was represented by the N-H and O-H stretching groups, could be seen in the absorption band 1456.26 in the wave range 3000–30500. The conclusion of this study was that chitosan could be extracted from shrimp shells and meet the characterization criteria.
Antibacterial Activity and Determination of Total Phenol and Flavonoid of Carica papaya L. Ethanol Extract Karo-Karo, Sry Ulina; Arianto, Anayanti; Salim, Emil
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.738

Abstract

Infectious diseases are Indonesia's most common. Antibiotics are used to treat infections. Medicine needs new antibiotics due to antibiotic resistance. Antibiotics from plants are possible. Papaya leaf carpain alkaloids may be antibacterial. This study determined papaya leaf compound content, flavonoids' total phenol content, and the optimal concentration of papaya leaf ethanol extract that inhibits Staphylococcus aureus and Pseudomonas aeruginosa. The first stages of the research were the maceration of papaya leaf extract with 96% ethanol solvent, the phytochemical screening test (alkaloid, flavonoid, saponin, tannin, and steroid and triterpenoid tests), total phenol and total flavonoids tests, and the paper disc antibacterial activity test. Alkaloids, flavonoids, glycosides, tannins, steroids, and saponins were found in papaya leaf ethanol extract. Papaya leaf ethanol extract has 59.05 mgQE/g flavonoids and 56.80 GAE/g phenols. The antibacterial activity test of papaya leaf ethanol extract measured the diameter of the inhibitory zone on Staphylococcus aureus and Pseudomonas aeruginosa. Alkaloids, flavonoids, glycosides, tannins, steroids, and saponins were found in papaya leaf ethanol extract. Papaya leaf ethanol extract has 59.05 mgQE/g flavonoids and 56.80 GAE/g phenols. Papaya leaf ethanol extract had the best inhibition zone diameter for Staphylococcus aureus at 150 mg/mL (12.85 mm) and Pseudomonas aeruginosa at 150 mg/mL (13.10 mm).

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