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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 502   503   504   505   506 
Effect of Cacao on Plasma F2-Isoprostane Level, CD34 and ICAM-1 Expression of Coronary Arteries in Cigarette Smoking Exposed Rats Dina Helianti; Soetjipto; Widjiati; I Ketut Sudiana
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15729

Abstract

This research aimed to evaluate cardioprotective effects of cacao in smoking exposure condition that the effects were mediated through the anti-oxidant pathway by measure plasma F2-isoprostane level, Endothelial Progenitor Cell (EPC) enhancement by expression of CD34, while dysfunction endothelial condition was measured by expression of ICAM-1 in coronary arteries. This study subjected rats, divided into four groups: the normal control group (2 ml of aqua bidest, air exposure); the cigarette control group (2 ml of aqua bidest, cigarette smoke); cacao group 1 (1205 mg/kg BW/day, cigarette smoke); cocoa group 2 (2410 mg/kg BW/day, cigarette smoke). The oxidant biomarker, F2-isoprostane level was assessed using ELISA; CD34, and ICAM-1 expression in coronary arteries by immunohistochemistry. Cacao 1205 mg/kg BW/day significantly decreases plasma F2-isoprostane level, and ICAM-1 expression of coronary arteries in cigarette smoking exposed rat (p < 0.05) but there was not a significant increases CD34 (p < 0.05). Cocoa in cigarette smoke-exposed rats can prevent endothelial dysfunction through decrease F2-isoprostane but not increase CD34. The results of this study can be used as a basis for preventing endothelial dysfunction due to cigarette smoke by using cacao.
Determination of Antioxidant Compounds, Antibacterial Activity and Minerals Content of Broccoli Dhuha M.A.AL-Altaie; Zuhair Radhi Addai
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15730

Abstract

The aim of this study was to examine the antioxidant compounds, antibacterial activity and minerals content of broccoli stem and floret. The antioxidant activity was determined by measuring total phenolic content (TPC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH). The antibacterial activity was determined using paper disc method against two bacteria namely Klebsiella sp, Escherichia coli, Staphylococcus aureus and P. aeruginosa. Minerals concentrations of broccoli stem and floret were determined using atomic absorption spectrometry. The results showed that floret sample had significantly (P <0.05) higher total phenol content and antioxidant activity compared to stem sample. The result showed that the acetone extracts of broccoli stem and floret were effective against all the bacteria tested. The majority of the broccoli materials were rich in some of the essential minerals like Na, K, Ca, Mg, Mn, Cu, Fe, and Zn, which are known to be beneficial for health. In general, the concentrations of minerals in the broccoli stem and floret were detected. broccoli floret higher minerals concentration of K, Ca, Mg, Mn, Cu, Fe, and Zn of floret than stem. Results showed part of plant effect of the antioxidant compounds and minerals content. Results of the present study provide vital data on the availability of some antioxidant compounds and essential minerals, which can be useful to provide dietary information for designing value-added foods and for food bio fortification.
The Role of Aloe vera and Centella asiatica to the Improvement of Skin Barrier Function in Indonesian Batik Workers Damayanti; Menul Ayu Umborowati; Sylvia Anggraeni2; Cita Rosita Sigit Prakoeswa
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15731

Abstract

Background: The batik industry uses dyes and candles, that can disrupt the skin barrier function and may precipitate skin disease. Objective: To determine the role of Aloe vera and Centella asiatica to the improvement of the skin barrier function in Indonesian batik workersMethods: This was a double blind clinical trial of 30 Indonesian batik workers were divided into 2 group and given Aloe vera or Centella asiatica topical randomly was applied twice a day. Transepidermal water loss (TEWL) level, stratum corneum hydration level, and pH level, were examined using Cutometer dual MP-580. Result: Sensitivity (Sn) of new local compared with imported allergen extracts in this study was between 15.38%-84.61%, the highest point was house dust mite extract. Specificity (Sp) was ranged from 81.48%-93.75%, the highest rank was shrimp extract. Compared with IgE results, the Sn of new local and imported house dust mite extracts was good (85.7%; 92.9%). The Sp was good for egg white and cow’s milk new local extracts (86.4%; 84.4%). Conclusion: Aloe vera topical gave significant improvement on palm area of TEWL level (P=0.033; CI 95%), stratum corneum hydration (P=0.000; CI 95%), and pH level (P=0.004; CI 95%); while on dorsal hand area of stratum corneum hydration (P=0.002; CI 95%). Centella asiatica topical gave significant improvement on palm area of stratum corneum hydration (P=0.007; CI 95%); while on dorsal hand area of stratum corneum hydration (P=0.001; CI 95%) and pH level (P=0.17; CI 95%). No significant differences of Aloe vera compared to Centella asiatica in the improvement of skin barrier function.
A Study to Assess the Effectiveness of Planned Teaching Programme on Prevention of Selected Life Style Diseases in Terms of Knowledge and Attitude among Male Adults at Selected PHC of Kheda District Darshana B. Suthar; Kailash Nagar
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15732

Abstract

Background of Study: The World Health Organization (WHO) estimates that life style diseases (with mostly preventable risk factors) are biggest killer across the world. Globally, 60% people die each year from life style diseases. 70% deaths are preventable from all non-communicable diseases by modifying life style. Lifestyle diseases are diseases linked with the way people live their life1. These are non-communicable diseases. This is commonly caused by lack of physical activity, unhealthy eating, alcohol, drugs and smoking2.Objectives: 1. To assess the knowledge and Attitude of male adults before and after administration of a planned teaching programme regarding prevention of selected life style disease. 2. To compare the knowledge and attitude score before and after teaching program. 3. To find out the association of post test attitude score regarding prevention of selected life style diseases with their selected demographic variables.Methodology: The research design adopted for the study was one group pretest posttest, quasi experimental research design3. 50 male adults were selected from selected PHC of kheda district by convenient non probability sampling technique and structured knowledge questionnaire and Likert’s attitude rating scale were prepared to assess the knowledge and the attitude of samples. Reliability of structured knowledge questionnaire and likert’s attitude rating scale were ascertained by using test retest method.Results: The study was conducted at Salun PHC. pre-test knowledge range was 7.27, mean was 14.74, standard deviation was 4.28, median was 14.00 and mode was 12.00 and post-test knowledge range was 21.30, mean was 26.12, standard deviation was 2.20, median was 27 and mode was 27.while pre-test attitude range was 43.55, mean was 50.04, standard deviation was 2.83 and median was 51.and post-test level of attitude, 49(98%) had favourable attitude, 1 (2%) had moderately favourable attitude and none of them had unfavourable. The maximum score was 30, mean was 11.38, standard deviation was 2.47 and paired t-test value was 32.53 that hence there exists a significance effectiveness on level of knowledge before and after administration of planned teaching programme among male adults. The maximum score was 60, mean was 3.40, standard deviation was 3.03, mean percentage was and paired t-test value was 07.93 that hence there exists a significance effectiveness on level of attitude before and after administration of planned teaching programme among male adults
Study on Heart Measurements of the People between the age 20-40 Years Present to the Teaching Hospital Colombo North – Post mortem Study De Silva RLSK; Kitulwatte IDG; Priyanath DC; Gunathilake MMAC; Senanayake TAAW; Kumari MKJK
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15733

Abstract

Introduction: Presence of an enlarged heart provides a basis for determination of the cause and mechanisms of death. Gender, physical activity, and Body Mass Index (BMI) may affect the size of organs. Knowledge on such normal variations is needed in order to recognize the abnormalities.Objectives- This research was conducted to study the dimensions of the heart(heart weight, left ventricular thickness and valvular circumferences) among the young adult healthy deceased autopsies and evaluate their association with different variables.Methods: It was a descriptive cross-sectional study and 20-40 years of age healthy, young, adult, males and females in equal numbers who had died suddenly were studied by considering the inclusion and exclusion criteria. Details of the past history and the measurements were entered into a proforma and the anonymous data were used for analysis.Results: The study revealed that the mean values of the heart weight was 280.52g (SD+/- 42.60), it was 293.94g (SD+/-39.29) for males and 267.10g (SD+/-42.64) for females. There was no significant association of heart weight with gender (P= 0.46410). There was a significant association between BMI and the heart weight of the females (P= 0.0387), no such association for left ventricular wall thickness. Further, there was a significant difference of the tricuspid valve circumference among two genders and the values were 11.6cm (SD+/-0.82) for males and 10.7cm (SD+/-0.6) for females.Conclusions: Majority of the findings was consistent with the findings of the studies globally on Caucasians. Increased body mass index was significantly associated with increased heart weight among females which could probably be explained as a consequence of increased epicardial fat since there was no such association for left ventricular wall thickness.
The Need for Specialist Doctors in the Development of Type B General Hospital at Regional Level Desy Martha Panjaitan; Widyana Beta Arthanti; Mokhamad Khoirul Huda
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15734

Abstract

Regulation of the Minister of Health No. 3 of 2020 on Hospital Classification stated the classification of a hospital is no longer based on the number of specialist and subspecialty services as in the previous provisions, but rather emphasizes the number of beds. However, type B hospitals’ problem is not the number of beds, but the lack of complete facilities, the availability of human resources such as the need for specialist doctors and the unequal distribution of type B hospitals at the regional level. This research aims to find out programs to fulfil the needs for specialist doctors in developing type B hospitals at the regional level. The results showed that the program to fulfil the needs for specialist doctors of type B hospital in the region could be as shortterm, medium-term and long-term programs. Specialist doctor education scholarship programs are a better solution to fulfil type B hospitals’ needs at the regional level. Thus, the fulfilment of the need for specialist doctors will improve the quality of health services.
Individual-Level Factors Associated with Quality of Life among TB Patients Dhian Satya Rachmawati; Nursalam Nursalam; Rachmat Hargono; Mochammad Amin; Nyoman Anita Damayanti
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15735

Abstract

Background: Due to the high incidence of tuberculosis (TB) in Indonesia, evaluating important factors of the TB patients’ quality of life is crucial. Individual-level factors play an essential role in enabling TB patients to manage their perceived needs and treatments to sustain the Quality of Life (QoL). Yet little is known about the relationships between individual-level factors and the QOL of TB patients in Indonesia. This study aimed to evaluate the association between individual-level factors (physical health, emotional state, social support, spirituality) and quality of life in TB patients. Methods: A cross-sectional study was conducted using a simple random sampling strategy, 73 TB patients were chosen based on their availability during data collection, and consent to participate in the study. The data were collected from a community sample of Surabaya City, East Java, Indonesia. In the present study, the following instruments were used: Early Warning Score System (EWSS), Depression Anxiety Stress Scale (DASS)-21, MOS Social Support Survey-14, Daily Spiritual Experience Scale (DSES), and the World Health Organization Quality of Life (WHO-QoL). Spearman’s rank correlation coefficient was used to discover the association between variables. Results and Discussions: The results showed that there were significant relationships between physical health (p = 0.037), emotional state (p = 0.04), social support, spirituality and QoL (p = 0.001). Conclusion:In conclusion, individual-level factors associated with TB patients’ quality of life: physical health, emotional state, social support, and spirituality.
Associations between P53, Transforming Growth Factor Beta-1, and Interleukin-10 Serum Levels with Advanced Liver Disease and Hepatitis B Virus Infection Citrawatidyahkencono Wungu; Mochamad Amin; Ulfa Kholili; Gwennyichsan Prabowo; Poernomoboedi Setiawan; Soetjipto; Retno Handajan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15736

Abstract

Leptospirosis Transmission in Ponorogo District of East Java, Indonesia Corie Indria Prasasti; Aditya Sukma Pawitra; Khuliyah Candraning Diyanah; Moch Irfan Hadi; M. Yusuf Alamudi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15737

Abstract

This study aims to identify Leptospira bacterial infection in livestock owners and their livestock, as well as to examine potential risk factors correlated with the incidence. 50 participants were selected and their blood samples were collected. 50 urine samples were collected from livestock owned by the participants. Polymerase Chain Reaction (PCR) was used to identify the existence of the Leptospira bacteria. The questionnaire instrument was used to obtain information about individual characteristics and hygiene. The Chi-Squared test was adopted to examine the correlation between outcome and explanatory variables. The confirmation PCR test detected the bacterial DNA in 2 out of 50 blood samples examined (4%) and 3 out of 50 urine samples examined (6%). Human leptospirosis incidence is significantly correlated with occupation type (p=0.035), personal protective equipment (PPE) use (p=0.044), water puddle contact (p=0.044), cage sanitation (p=0.044) and Leptospira bacteria presence in livestock urine (p=0.007). Insignificant correlation was showed in owners’ age variable. The presence of Leptospira bacteria both in livestock and the owners indicates the real threat of animal to human transmission. Further study with larger sample size and wider range variables and meticulous examination technique is required to comprehend the investigation.
Diagnostic Value of Serum Procalcitonin in Hospitalized Sepsis Patients Cut Murzalina; Bakhtiar Bakhtiar; Hanifah Yusuf; Buchari Buchari
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15738

Abstract

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