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Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
Effect of Moderate-Intensity Acute Physical Activity on Decreasing Cortisol Levels in Obese Female Cornelius Coli; RizkaEka Prasetya; GadisMeinar Sari; Purwo Sri Rejeki
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15719

Abstract

The Dynamics of Macrophage Function in Reparation of Natural Immune System in Tuberculosis Disease Christina Destri; Jusak Nugraha; Muhammad Amin; Djoko Agus Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15720

Abstract

Macrophages related with pathogen was involved the ability of Mycobacterium tuberculosis (Mtb) to developing mechanisms to prevent macrophage attacks and the aim of this study was to find the relationship between specific role of macrophages in natural immune system in tuberculosis (TB) disease. The research design of this study used literature reviews from various journals and it was accessed in Google Scholar and various medical science websites who bublessed less than 10 years. Localization of mycobacteria in granulomas form and activation of macrophages ability to kill and eliminate pathogens also the movement of M1 to M2 polarization as an important part for the host to prevent widespread tissue damage. However, the loss of the immune system suppression by M1 and Th1 molecules will give benefit to fertility development of Mtb in the environment of immunity M2 / Th2. The results of this study showed that the dynamics of macrophages in tuberculosis disease is a balance of Mtb’s ability to escape from the immune system. The effectiveness of anti-TB treatment repair the immune system and eliminate Mtb
Prevalence of Gestational Hypertension and Pregnancy Outcome Bhat AV; Kharde SN
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15721

Abstract

Introduction Hypertension during pregnancy is considered as one the high risk as it is one of the cause for maternal and neonatal mortality and morbidity. Aims: This study is aimed to find the prevalence of gestational hypertension and to understand the pregnancy outcome. Settings and Design: Study conducted at tertiary care hospital and descriptive research design was used for the study Methods and Material: Sample size was 366 women with gestational hypertension were included. Data was collected by using investigator prepared self-administered questionnaire Statistical analysis used: inferential statistics analytical methods Results: Results revealed that prevalence of gestational hypertension 9.8%. Maternal outcome 53% delivered at 34 to 38 weeks, mode of delivery (52.5%) were delivered by C-section, 56.3% women were induced, 97.3% were singleton pregnancy, About the gender of new-born 51.9% were male, 67.2% were born with Normal (>2500g) weight, NICU admission 20.5% and reason for NICU admission was prematurity. Conclusions: The knowledge of risk factors for gestational hypertension in pregnancy may give tracks for prevention in this population.
Effectivity of Essential Oil Diffuser Blend Aromatherapy for Decrease Morning Sickness in The First Trimester of Pregnancy in Wonokromo Surabaya Fritria Dwi Anggraini; Fauziyatun Nisa; Siska Nurul Abidah
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15722

Abstract

Radiographic Evaluation of Dental Age in Adults Using Digital Orthopantomograph Bhavika Sachin Vhatkar; Mandavi Shailesh Waghmare; Naveen Kumar Shetty; Siddharth Acharya; Kapil Sharad Gavand
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15723

Abstract

Introduction: Age estimation isimportant for administrative and ethical reasons and because of legal consequences. Dental pulp undergoes regression in size with increasing age due to secondary dentin deposition and can be used as a parameter of age estimation even beyond 25 years of age.Aims and Objectives: The purpose of the present study was to evaluate the feasibility of applying kvaal et al method of age estimation on maxillary second premolar & mandibular first premolar on OPG. Materials and Methods: It is a retrospective study, which involved 100 sample of OPG on KODAK 9000 IMAGING. Measurements were performed on the standardized digital panoramic radiographs based on Kvaal’s method. Different regression formulae were derived and the age was assessed. The assessed age was then correlated to the actual age of the patient using Student’s t-test.Results: In this study, there were no significant difference in estimated & actualage for both males and females.Conclusion: The study was an attempt to use KVAAL et al method of radiographic dental age estimation using OPG with minimal number of teeth.
GATA 3 Reactivity in Adenoid Cystic Carcinoma and Pleomorphic Adenoma of Salivary Glands Ali Zaki NAJI; Ammar Eesa Mahdi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15724

Abstract

Objectives: The main targets is evaluate clinicopathological distribution and comparison of immunohistochemical (IHC) expression of GATA 3 between in adenoid cystic carcinoma (ACC) and pleomorphic adenoma (PA) of salivary . Design and Methods: This retrospective analysis, open surgical specimens of salivary gland that were done , and consisting of 150 cases that divided into three groups: normal salivary gland tissues (n=50), adenoid cystic carcinoma(n=50), and pleomorphic adenoma(n=50). Clinical data (age, sex, previous diseases ), physical examination, and investigations are done for all patients. In addition. These 150 cases of paraffin embedding blocks of salivary tissue were stained by ordinary stained (hematoxylin and eosin staining ). Manual IHC staining of GATA 3 was done. Results: Age groups is younger for normal salivary gland tissues than PA, and ACC . Sex distribution was slightly increase in male in comparison to female in normal salivary gland tissues and PA. GATA 3 staining was showing more positivity in normal salivary gland tissues (43/50 patients) than PA (27/50 patients) and ACC (14/50 patients). This positivity in GATA 3 IHC staining were more in male sex, regarding 55.8% in normal salivary gland tissues than ACC 50% and PA 51.9% . Age group 31-40, 40-50 and 61-70 years were showing more positive GATA 3 IHC staining in normal salivary gland tissues, PA, and ACC respectively. there was insignificant association between GATA 3 IHC staining with either age groups or sex groups distribution . Conclusion: GATA3 IHC is good marker and can used for searching salivary gland tumor origin, assisting in diagnosis Salivary gland tumors subtypes but GATA3 IHC staining has no association to specific sex or age groups in Salivary gland tumors. Usage of surgical operations for histopathological specimens preparation are better and give good efficiency for IHC markers staining.
The Effect of Golden Sea Cucumber (StichopusHermanii) Extract on the Healing Process of the White Rat (Rattus Norvegicus) Indicated by Oral Ulcer– A Literature Review Dio Rafid Prakoso; Diah Purwaningsari; Sihning E.J.Tehupuring; Wachjudi Kurnia
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15725

Abstract

Background Indonesia is a maritime country that is rich in marine resources. There are many marine resources that can be used as herbal medicine. One of them is the golden sea cucumber which is thought to be used as an alternative medicine to speed up the healing process of oral ulcers. The purpose of this study was to determine the effect of golden sea cucumber extract (Stichopushermanii) on the wound healing process in rats with oral ulcers.Method This research is a descriptive study with a literature review design. The articles used are articles published in international and national journals in the 2015-2020 period and are indexed by Scopus, Thomson Reuters, Web Science, Scimago and Sinta.Result The results of the scoping article show that there are active compounds in golden sea cucumbers, namely glycosaminoglycans that consist of hyaluronic acid, heparin / heparan sulfate (HP / HS), chondroitin sulfate / dermatan sulfate (CS / DS) and keratin sulfate (KS) which can form proinflammatory cytokines to trigger the emergence of immune defense cells and can bind to growth factors such as FGF2, VEGF, TGF-b, which will provide stimulation to accelerate the angiogenesis process, fibroblast ploriferation, endothelial differentiation, epithelial differentiation so as to accelerate the wound healing process.ConclutionThe conclusion of this study is the golden sea cucumber has the potency to accelerate the wound healing process by increasing fibroblast formation, collagen synthesis, endothelial differentiation and epithelial differentiation.
Determinants of Tobacco Use among Adolescents and Young Adults in Indonesia: An Analysis of IFLS-5 Data Diyan Effendi; Arief Priyo Nugroho; Zainul Khaqiqi Nantabah; Agung Dwi Laksono; Lestari Handayani
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15726

Abstract

Background:The danger of tobacco use to health has been globally known. However, its prevalence especially in developing countries including Indonesia remains high.This study aims to investigate determinants of tobacco use among adolescents and young adults in Indonesia. These age groups are essential since most regular smokers initiated to smoke at these ages. Methods: This study utilized IFLS wave 5 data. A total of 7213 responses on tobacco use from respondents age 15-24 years old were taken into analysis. Association between tobacco use with sociodemographic, religious, and ethnic identity was determined by using binary logistic regression. Results: Prevalence of tobacco use was 25.1%. The fully adjusted model showed factors that associated with tobacco use were age, sex, educational attainment, marital status, having smoking parents, and Madurese ethnicity. Conclusion:Tobacco use was prevalent among adolescents and young adults in Indonesia. Madurese was the only ethnic group associated with tobacco consumption in Indonesia. Appropriate design of interventions, therefore, is needed to target these subgroups.
The Effect of Iron Nanoparticles (FeNPs) on Some Biological and Hematological Parameters in Albino Rats Dilsher. A. Mohammed; Omar A. M. Al-Habib
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15727

Abstract

Background: Nowadays, iron nanoparticles and other nanomaterials are widely used in many fields including industrial and biomedical fields. Yet many concerns remain about their fate and toxicity to living organisms. Objective: The aim of the current study was to evaluate the risk of using iron oxide nanomaterials as food additives for animals to increase its utilization compared to bulk size particles of the same material. Materials and Methods: The study included the effect of two different nano-sized iron oxides (25 nm and 50 nm) at two doses (1 mg/kg feed and 10 mg/kg feed) on some biological and hematological parameters in male albino rats. Results: The results indicate that rat’s performance, growth, feed conversion rates were not affected with no sign of toxicity. Most of the hematological parameters in all treated groups were not affected by IONPs except one group which showed a significant difference in the percent of granulocytes compared with the control. Conclusion: It can be concluded that iron oxide NPs of different sizes and doses did not affect their performance, growth rate, hematological parameters with no sign of toxicity.
Optimizing Role and Synergy of Indonesian National Police for Handling Prevention of Covid-19 Spread: A Case Study in Human Resource Development Perspective Dimas Agung Trisliatanto; Anis Byarwati; Sri Iswati; Arif Rahman Nurdianto; Fery Setiawan; Heribertus Agustinus Bilo Tena; Hendro Puspito
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15728

Abstract

Background: The rise in cases of violations and criminal acts handled by the Indonesian National Police during the COVID-19 pandemic recorded 18 cases of hoarding and increasing prices for personal protective equipment and other items. This study aims to describe and describe the optimization and synergy of the Indonesian National Police in handling the prevention of the spread of COVID-19. Method: This study used a qualitative approach with a case study method which is explored and analyzed based on the data and research information obtained. Result: This study showed that the role of Bhayangkara Fostering Public Security and Order of Indonesian National Police as the Development of Public Security and Order can be optimized to educate the public to prevent hoaxes or stigma regarding this corona virus. This synergy between the Indonesian National Police, the Indonesian Army and the Community Health Center is urgently needed to avoid data falsification and vaccine abuse in the community. Conclusion: This study concluded that the Indonesian National Police optimizes the role and synergy collaboratively with the community and the Government by relying on the Sector Police as the basis for early detection of potential security problems in the community, especially related to handling COVID-19.