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Jurnal Farmasi
Published by Sekolah Tinggi Ilmu Kesehatan Nasional
ISSN : 23027436     EISSN : 26568950     DOI : https://doi.org/10.37013/jf
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
JURNAL FARMASI (Journal Of Pharmacy) adalah jurnal ilmiah resmi yang dikeluarkan oleh Sekolah Tinggi Ilmu Kesehatan Nasional dengan nomor p-ISSN 2302-7436 e-ISSN 2656-8950. JURNAL FARMASI (Journal Of Pharmacy) berisikan jurnal-jurnal ilmiah dalam semua aspek ilmu pengetahuan dan teknologi di bidang Farmasi dan kesehatan antara lain: Farmakognosi dan Fitokimia meliputi Pengembangan Simplisia, Budidaya Tanaman Obat, Isolasi, Skrining Fitokimia, dan Identifikasi Obat Bahan Alam Indonesia. Biologi meliputi Biologi Molekuler, Bioteknologi, Mikrobiologi, Immunologi, Parasitologi, Biomedisinal Teknologi Farmasi meliputi Farmasetika, Teknologi dan Formulasi Sediaan Obat, Teknologi dan Formulasi Sediaan Obat Bahan Alam Indonesia. Ilmu Kimia meliputi Kimia Analisa, Kimia Organik, Sintesa Obat, Kimia Medisinal, Pemodelan Molekul, Biokimia, dan Kimia Lingkungan. Farmakologi meliputi Farmakologi, Farmakokinetik, Farmakoterapi, dan Toksikologi. Farmasi Klinik dan Komunitas meliputi Farmakoekonomi, Farmakovigilan, Analisis dan Evaluasi Penggunaan Obat, Monitoring Efek Samping Obat, Analisa Kebijakan Kefarmasian, Evaluasi kegiatan Kefarmasian, Evaluasi Efektifitas Penggunaan Obat, Evaluasi Kualitas Hidup Pasien.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 189 Documents
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FORMULASI DAN UJI ANTIJAMUR Candida albicans KRIM EKSTRAK RIMPANG KENCUR (Kaempferiae galanga Linn.) DENGAN VARIASI ASAM STEARAT DAN TRIETANOLAMIN Irawan, Ira; Aisiyah, Siti; Purwaningsih, Desi
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/qzxj1g27

Abstract

The active compounds contained in the rhizome of kencur (Kaempferia galanga Linn.) include alkaloids, flavonoids, and tannins which are used as antifungals. This study aims to determine the effect of variations of stearic acid and triethanolamine on the physical quality and stability of cream preparations and their activity against Candida albicans ATCC 10231 and cream formulation formulas with the best physical quality and have antifungal activity. Kencur rhizome extract was obtained by maceration using 70% ethanol and formulated with an extract concentration of 12% and variations of stearic acid and triethanolamine with a ratio of (10:7, 13:5, 16:3). The formulation of the cream preparation was carried out by mixing the oil phase and the water phase and then physical quality was carried out including organoleptic tests, homogeneity, spreadability, adhesion, pH, viscosity, and Cycling test. This study used the disc diffusion method to determine antifungal activity and one way ANOVA for statistical analysis. The results showed that the diameter of the extract inhibition zone was 13.17 mm. Variations of stearic acid and triethanolamine affect the physical quality and antifungal activity of cream preparations. Cream preparations have antifungal activity against Candida albicans ATCC 10231. The best formula is formula 1 with variations of stearic acid : triethanolamine (10:7) which has the best physical quality, with an inhibition zone diameter of 13.00 mm which is strong in inhibiting fungal growth.
AKTIVITAS ANTIBAKTERI MINYAK ATSIRI SEREH WANGI (Cymbopogon citratus) TERHADAP BAKTERI Escherichia coli, Propionibacterium acne, Staphylococcus aureus Hermawati, Ema; Tanfil T, Ardy; Bayu Chandra, Pra Panca
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/ad3c0p16

Abstract

Citronella oil (Cymbopogon citratus) is an essential oil that has potential as an antibacterial. The main compounds of citronella oil are citronellal, geraniol and citronellol. The purpose of this study was to determine the bacterial inhibitory activity of citronella essential oil against Escherichia coli, Propionibactaerium acne, Staphylococcus aureusbacteria. The research method used was an experimental laboratory using a basic research design completely randomized design (CRD) with a factorial pattern of 24 hours incubation time at 37oC and different concentrations of citronella oil (Cymbopogon citratus) (10%, 20% and 30%) compared to comparator, namely tetracycline. The antibacterial test used the disc diffusion method. The results of the antibacterial activity test of citronella essential oil (Cymbopogon citratus) showed results as a strong category, namely having an inhibition zone ranging from 10-20 mm. The optimum concentration to inhibit the bacteria Escherichia coli, Propionibacterium acne, Staphylococcus aureus is at a concentration of 30%.
PENGARUH PEMBERIAN JUS STROBERI TERHADAP KADAR HEMOGLOBIN PADA MAHASISWA Indah Sekar Kinasih, Mutiara; Saroh, Dewi
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/xpshsa19

Abstract

Student are one of the groups that are prone to suffer from anemia. Strawberries contain 60 mg of vitamin C. The increase in hemoglobin levels is influenced by the presence of vitamin C in the body. The purpose of this study was to determine the effec of strawberry juice consumption to hemoglobin levels. The research design used was experimental analytics with pretest and posttest approaches. The sampling technique used was purposive sampling. Sample of 28 female students at Level 1 DIII Medical Laboratory Technology. Examination of hemoglobin levels using the cyanmethemoglobin method with a Microlab 300 photometer. The results of this study obtained average hemoglobin levels before consuming 11.28 and after consuming 12.58. A total of 26 respondents increased hemoglobin levels, and 2 respondents decreased. The paired T test results obtained a p = 0.000 (p < 0.05). So it can be concluded that there is a significant influence of strawberry juice consumption on hemoglobin levels.
UJI AKTIVITAS ANTIPIRETIK EKSTRAK ETANOL BAWANG LANANG HITAM (ALLIUM SATIVUM L.) PADA TIKUS PUTIH JANTAN DENGAN METODE PERKOLASI Pramesti Listya Agatha, Cindy; Wisnu Kusuma, Eka; Ingrid Anggaraini, Devina
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/kq3qkw49

Abstract

Black Onion (Allium Sativum L.) is a species of garlic that is fermented and widely used in food or health. This study aims to determine the black male onion extract antipyretic effectiveness along with to determine the impact of ethanol extract black male onion at dossage of 50mg/KgBb, 100mg/KgBb, 200mg/kgbb on male white rats induced brewer's yeast.. In this study, 25 male white rats were given five treatments: a negative control (CMC-Na), a positive control (Paracetamol 45mg/KgBb), and black onion extract treatment groups with dosages of 50mg/KgBb, 100mg/KgBb, and 200mg/KgBb. Brewer's yeast was administered intraperitoneally. Body temperature is measured rectally with a digital thermometer every 30 minutes for 150 minutes. The data obtained were used to calculate AUC, and the mean data of AUC was analyzed by saphiro wilk test and one-way ANOVA test. Body temperature measurements revealed that an ethanol extract of black onion had the most potent antipyretic effect at a dosage of 100 mg/KgBb
TINJAUAN ARTIKEL : UJI MIKROBIOLOGI Nurul, Ahsana; Setiawan, Iwan; Yusa, Delia; Trisna, Dhea; Halisa, Nur; Putri, Odilia; Ekawati, Oktavia; Umi, Yuliana; Ze Fanya
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/hawgpe84

Abstract

Microorganisms such as bacteria are one of the causes of disease that many patients suffer. Bacteria can easily reach food or pharmaceutical preparations during the production process, so it is important to carry out antibacterial testing on a product to ensure product safety and quality. The activity of an antibacterial can be observed by several methods such as diffusion, dilution and broth microdilution. The purpose of this article review is to provide information regarding microbiological tests that can be used to test antibacterial activity. The method used is an online search for international journal literature using online search sites such as Google schoolar, Pubmed and Scopus. Various studies have found, it is known that the antibacterial activity test consists of three types. The first diffusion method consisting of a diffusion disc and wells. The purpose of the diffusion method is to determine the sensitivity and resistance of a bacterium to antibiotics. The two dilution methods consist of solid dilution and liquid dilution. The purpose of the dilution method is to determine the Minimum Inhibitory Concentration (MIC) and Minimum Killing Concentration (MBC). The effective microdilution of the three broths was used to determine the Minimum Inhibitory Concentration (MIC) and Minimum Kill Concentration (MBC). In the antibacterial activity test a bacterial inhibition zone will appear which will be measured according to the results. The size of the diameter of the inhibition zone will increase with increasing concentration of antibiotics.
EVALUASI PENYIMPANAN OBAT DI APOTEK INDRA SUKOHARJO Dwi H, Aminah; Hartono
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/rk5yvz94

Abstract

Regulation of the Minister of Health of the Republic of Indonesia No. 73 of 2016 concerning Pharmacy Pharmaceutical Service Standards states that pharmacies are a means of pharmaceutical services where pharmaceutical practices are carried out by Pharmacists. Pharmaceutical service standards that aim to improve the quality of pharmaceutical services, security, storage and distribution or distribution of drugs, services on prescriptions or not with prescriptions, drug information services, guarantee legal certainty for pharmaceutical personnel, and protect patients and the public from irrational use of drugs in the context of patient safety. Good drug storage will ensure the quality of drug preparations, avoid irresponsible use of drugs, maintain the availability and service of pharmaceuticals and facilitate the search and supervision. Evaluation of good drug storage should be carried out by all pharmaceutical services including pharmacies. This study aims to evaluate drug storage in Indra pharmacies based on the physical condition of drug storage shelves and warehouses, how to store drugs, record stock cards, and safeguard drug quality. This research is a type of observational research by observing objects and the results are presented descriptively, and data collection is carried out by documentation and interviews at the Pharmacist in Charge of Apotek Indra Sukoharjo. The results of the evaluation of drug storage at Indra Sukoharjo Pharmacy as many as 77.8% have met the standards in accordance with the Regulation of the Minister of Health Number 73 of 2016 concerning Pharmaceutical Service Standards in Pharmacies. The results of the evaluation of the condition of the rooms and facilities in the drug storage warehouse of Apotek Indra Sukoharjo based on the Technical Guidelines for Good Drug Distribution Methods set by the Food and Drug Control Agency in 2020 were 54.2% who had met the standards and 45.8% had not met the standards.
OPTIMASI GELLING AGENT PADA SEDIAAN GUMMY CANDY PARASETAMOL DENGAN METODE SIMPLEX LATTICE DESIGN Pradana, Arsitya; Aisiyah, Siti; Purwaningsih, Desi
Jurnal Farmasi (Journal of Pharmacy) Vol. 13 No. 1 (2024): Jurnal Farmasi (Journal of Pharmacy), April 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/p6a5c155

Abstract

The dosage form of paracetamol gummy candy has several advantages compared to other paracetamol preparations circulating in Indonesia, including fast onset, high bioavailability, pleasant taste, practical to use, easy to serve, acceptable to children, so can increase the impact of taking the drug. The aim of this research was to determine the effect of varying concentrations of gelatin and carrageenan on the elasticity, pH and air content of paracetamol gummy candy preparations and to determine the proportion of gelatin and carrageenan in the optimum formula using the Simplex Lattice Design method. The paracetamol gummy candy formula design from Design Expert SLD produced 8 runs with varying concentrations of gelatin and carrageenan. Critical parameters in determining the optimum formula include elasticity, pH and air content. Validation of the analytical method for testing the uniformity of paracetamol content of gummy candy using a UV-Vis spectrophotometer includes the parameters of accuracy, precision, specificity, linearity, LOD and LOQ. The researchers discovered that the amount of gelatin and carrageenan in paracetamol gummy candy preparations affected the elasticity, pH, and water content. Carrageenan has a dominant influence on boosting pH and water content, while gelatin has a dominant effect on improving flexibility. The best formula had 599,226 mg of gelatin and 400,774 mg of carrageenan.
TINGKAT PENGETAHUAN, PERSEPSI DAN SIKAP PASIEN TERHADAP KEHALALAN OBAT BATUK SIRUP DI APOTEK FARMARINDO BANYUMAS Wijayanti, Rina; Mulya Prayoga, Deden; Priyatno, Sugeng
Jurnal Farmasi (Journal of Pharmacy) Vol. 13 No. 1 (2024): Jurnal Farmasi (Journal of Pharmacy), April 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/hax14n07

Abstract

Medicine is one of the pharmaceutical products that has an important role in health. Medicine plays a role in reducing morbidity and mortality rates and improving a person's quality of life. Alcohol or khamr is one of the ingredients that is forbidden by Allah SWT. One medicine that contains alcohol is cough syrup. Many patients do not know whether cough syrup is halal. Therefore, this study aims to determine and measure the level of knowledge, perceptions, and attitudes of patients regarding the halalness of cough syrup containing alcohol at the Farmarindo Banyumas Pharmacy. This research is descriptive. Data collection was carried out using a questionnaire. Sampling used a purposive sampling technique with a total sample of 80 respondents. The results of the research show that the level of knowledge of respondents at the Farmarindo Banyumas Pharmacy regarding the halalness of cough syrup containing alcohol is 45% in the poor category, 10% in the sufficient category, and 45% in the good category. The level of perception of respondents at the Farmarindo Banyumas Pharmacy regarding the halalness of cough syrup containing alcohol is 79% in the good category and 21% in the very good category. The level of attitude of respondents at the Farmarindo Banyumas Pharmacy regarding the halalness of cough syrup containing alcohol is 74% in the good category and 26% in the very good category. It can be concluded that the level of knowledge, perceptions, and attitudes of respondents towards halal cough syrup medicine is in a good category.
OPTIMASI DOSIS EKSTRAK ETANOL BUAH DUKU (Lansium Domestikum Corr.) UNTUK EFEKTIVITAS DIURETIK TERHADAP TIKUS JANTAN GALUR WISTAR Niza, Hairun; Fahrozi, Hikmal
Jurnal Farmasi (Journal of Pharmacy) Vol. 13 No. 1 (2024): Jurnal Farmasi (Journal of Pharmacy), April 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/5vw7jd96

Abstract

Research has been carried out on optimizing the dose of ethanol extract of Duku fruit (Lansium domesticum corr) for the effectiveness of diuretics in male Wistar rats. This research uses quantitative methods. The animals used in this research were 25 male Wistar rats and were divided into 5 groups that had passed the acclimation period and had passed the urine volume collection period. Each group was given a different preparation, group I negative control was Na-CMC 0.5%, group II positive control furosemide 36 mg/kgBB, group III ethanol extract of duku fruit 50 mg/kgBB, group IV ethanol extract of duku fruit 100 mg /kgBW, and group V extra ethanol duku fruit 150 mg/kgBB. Urine volume measurements were carried out on days 8 to 21 every 12 hours. The data obtained were analyzed using statistical tests, Levene's test, Shapiro Wilk, two-way anova, and post hoc tests. The results of this study show that a dose of 150 mg/kgBB has diuretic activity in duku fruit plants with the average volume of urine collected in the 2nd week being 7.46 ± 3.27, in the 3rd week the average volume urine 9.92 ± 3.11. In the positive control, furosemide as a comparison, the average urine volume was 6.21 ± 3.56 in the 2nd week and in the 3rd week, the average urine volume was 8 ± 3.60.
UJI POTENSI EKSTRAK ETANOL BAWANG LANANG HITAM (Allium sativum L.) DALAM PENURUNAN KADAR KADMIUM DENGAN SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Ayu Trisnawati, Febiana; Ingrid Anggraini, Devina; Wisnu Kusuma, Eka
Jurnal Farmasi (Journal of Pharmacy) Vol. 13 No. 1 (2024): Jurnal Farmasi (Journal of Pharmacy), April 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/s8x11442

Abstract

Pollution caused by the discharge of waste into the waters will have an impact on water quality. Pollutants that can reduce water quality are heavy metal cadmium. Cadmium heavy metal when it enters the human body can cause toxic effects. The body needs an antidote to lower metal levels. Black onion (Allium sativum L.) contains flavonoids which are used as chelating agents. This study aims to determine the best concentration of ethanolic extract of black onion (Allium sativum L.) which can reduce cadmium levels maximally. The ethanolic extract of black onion was made in five concentration series, namely 0.2 ppm, 0.4 ppm, 0.6 ppm, 0.8 ppm, and 1 ppm. Cadmium metal (Cd) 20 ppm was treated with the addition of each concentration of black onion ethanol extract. The solution was separated with chloroform. The aqueous phase is an excess of cadmium metal which was analyzed by Atomic Absorption Spectrophotometry (AAS) at a wavelength of 228.8 nm. The results obtained showed that the best concentration of 0.8 ppm black onion ethanol extract could reduce metal cadmium (Cd) maximally which showed a percentage of 66.3906% with a coefficient of variation of 1.5873%.

Page 18 of 19 | Total Record : 189

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