cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Yayuk Andayani
Contact Email
sjp@unram.ac.id
Phone
+6281936732708
Journal Mail Official
sjp@unram.ac.id
Editorial Address
Jl. Majapahit No. 62 Mataram
Location
Kota mataram,
Nusa tenggara barat
INDONESIA
Sasambo Journal of Pharmacy
Published by Universitas Mataram
ISSN : 27232824     EISSN : 27232832     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Sasambo Journal of Pharmacy (p-ISSN: 2723-2824; e-ISSN: 2723-2832) is a scientific journal publishing original articles research in pharmaceutical science. The Journal is managed by the Pharmacy Study Program, Mataram University. Sasambo Journal of Pharmacy receives manuscripts in both English and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmaceutical Technology, Pharmacology and Toxicology, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Herbal Medicines, Pharmaceutical Microbiology and Biotechnology, Community Pharmacy, Clinical Pharmacy, and Pharmaceutical Education
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 94 Documents
 6   7   8   9   10 
Optimasi formula sampo ekstrak etanol daun delima (Punica granatum L.) dengan metode Simplex Lattice Design Jannah, Syifaul; Hajrin, Wahida; Hanifa, Nisa Isneni
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.347

Abstract

Anti-dandruff shampoo on the market still uses zinc pyriton which has the side effect of causing hair loss. Pomegranate leaves have strong antifungal activity against dandruff-causing fungi. This research aims to determine the optimum formula and physical properties of pomegranate leaf shampoo preparations with variations of SLS and cocamide DEA. The ethanol extract of pomegranate leaves was extracted by soxhletation and carried out in a tube test. Eight shampoo formula designs were determined using the SLD method. The shampoo was tested for foam height, pH, and viscosity to obtain the optimum formula. The optimum shampoo preparation was tested for physical properties, including organoleptic tests, homogeneity, foam stability, foam height, pH, and viscosity. The results of the test for the physical properties of the optimum shampoo preparation were verified using the SPSS application with the one-sample t-test method. Pomegranate leaf ethanol extract positively contains alkaloids, flavonoids, tannins, and saponins. The optimization results obtained the optimum shampoo formula, namely a combination of SLS 5.5% and cocamide DEA 15.5%. Optimum formula shampoo has a black color, menthol odor, gel form, ingredients mixed homogeneously, foam stability 81.83%, foam height 9.30 ± 0.26 cm, pH 5.91 ± 0.45, and viscosity 1646.66 ± 220.23 cP.
Influence of extraction method on total phenolic content and antioxidant activity of Sappan Wood (Caesalpinia sappan L.) extract Akmal, Tubagus; Tanjung, Yenni Puspita; Julianti, Andi Ika; Lestari, Aulia Gustiani; Aljan, Aljan
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.364

Abstract

Sappan wood is a botanical species that contains a high concentration of phenolic compounds, which contribute to several pharmacological properties, including antidiabetic, antibacterial, antioxidant, and wound-healing activities. In order to achieve phenolic compounds of high quality and quantity, it is crucial to select an appropriate extraction procedure. Plant extraction is an important step for chemical isolation, chemical analysis, and evaluating the biological and pharmacological activities of plant compounds. Therefore, determining the most favorable extraction conditions is a critical undertaking in order to maximize both the quantity of active plant compounds and the extraction yield. This research aimed to compare extraction methods based on total phenolic content (TPC) and antioxidant activity (IC50). The extraction techniques employed include maceration, stirring-assisted extraction (SAE), ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE). The results show TPC values for maceration, SAE, UAE, and MAE, which are 132.85±1.44, 150.99±1.69, 206.70±6.56, and 115.70±1.44 mg GAE/g DE, respectively. The DPPH antioxidant activity (IC50) values are 32.33±2.64, 25.01±0.34, 20.68±0.29, and 29.18±0.70 µg/mL, respectively. The research findings indicate that various extraction procedures can impact the extraction yield, total phenolic content (TPC), and antioxidant activity (IC50) of sappan wood, and UAE is the best extraction method.
Optimasi fase gerak dan analisis kadar natrium benzoat pada beberapa sirup rasa jeruk dengan metode kromatografi cair kinerja tinggi (kckt) Pulungan, Ainil Fithri; Santasa, Zhazha
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.372

Abstract

With the increasing growth of food and beverages in Indonesia, there has been an increase in the manufacture of soft drinks that use the preservative sodium benzoate, particularly in syrup. The concentration of sodium benzoate in beverages should be monitored, because excessive consumption can emerge various health problems. To obtain maximum analysis results, mobile phase optimization is first carried out, which aims to obtain the optimal type of eluent from several types of mobile phase, then proceed with adjusting the sodium benzoate content in the orange-flavored syrup using the HPLC method to establish whether it fits the standards in line with the BPOM Regulation No. 11 of 2019. After optimizing the mobile phase, the most optimal mobile phase is Methanol Pro HPLC: Aquabidestilata (70:30), because in this comparison the chromatogram gives the best result the peak shape is symmetrical, tailing factor is less than 2 and the retention time is less than 10 minutesBased on the findings of the third sample research, the sodium benzoate content in orange-flavored syrup meets the requirements of BPOM Regulation No. 11 of 2019, namely 600 mg/kg.
Analisa mutu tablet ibuprofen generik berlogo dan generik bermerek yang diproduksi industri X di Gresik Okta, Oktavia Noer Hidayah; Rahmawati, Dewi; Meliana, Marthy; Jalmav, Arianti; Ambari, Yani
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.388

Abstract

Ibuprofen tablets are one of the most widely used antipyretic analgesic drugs for self-medication in pharmacies. According to the Biopharmaceutical Classification System (BCS), Ibuprofen is included in Class II or drugs with low solubility, but high permeability. This study was carried out to determine the physical quality of branded generic and branded generic ibuprofen drugs.   This research was carried out by dissolution testing on ibuprofen tablets. The results obtained from the physical quality test met the specified requirements. The dissolution test showed that Q30 had dissolved more than 70%. The conclusion is that the drug meets the requirements and there is no difference between generic drugs with the logo and branded generics.
Analisis kualitatif bahan kimia obat dalam jamu pegal linu di wilayah kabupaten Grobogan Azri, Anna Sa'dia; Haresmita, Perdana Priya
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.341

Abstract

The use of traditional medicine in Indonesia, particularly jamu, remains very popular and an important part of the public health culture. According to the 2018 Riskesdas data, around 59.12% of the Indonesian population consumes jamu, and 95.6% of them recognize the health benefits obtained from it. Jamu, which is made from various types of plants, has been used for thousands of years to maintain health and treat various diseases. This study used Thin Layer Chromatography to identify Medicinal Chemicals (BKO) in jamu circulating in Grobogan Regency, Central Java. The purpose of this study was to analyze the content of medicinal chemicals in traditional herbal medicine. Six samples of jamu pegal linu were tested with Silica Gel 60 F254 stationary phase and different mobile phases for each standard. The results showed that all samples of jamu pegal linu tested did not contain the investigated BKOs, indicating product safety from this aspect.
Perkembangan targeted therapy pada kanker payudara dengan pertimbangan luaran biaya dan kualitas hidup: narrative review Puspitasari, Candra Eka; Annisa, Janatul; Yasykurah, Malva Marshaniswa; Hawarikatun, Baiq
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.448

Abstract

Breast cancer is a malignant tumour that grows in the breast tissue and can spread to the lymph nodes and metastasize to other parts of the body. Targeted therapy is currently developed as a therapeutic management for breast cancer with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-). This review aims to determine the effectiveness both in terms of clinical and cost on the use of single or combined targeted therapy when compared with conventional therapy, namely chemotherapy in breast cancer patients. The results show that the use of targeted therapy can provide greater health benefits in both single and combination use even though it can increase the cost of therapy.
Analisis waste pada depo rawat jalan dengan menggunakan lean hospital di Rumah Sakit Islam Siti Hajar Mataram Fauzi, Lalu Rizki; Anggraini, Eniza
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.470

Abstract

Pharmaceutical installations can provide substantial revenue if managed properly and efficiently. Good or bad service can affect patient satisfaction. For this reason, pharmaceutical installations must improve quality in terms of patient satisfaction, one of which is by reducing waste that occurs in the pharmaceutical service process in hospitals. This study aims to analyze what waste occurs in outpatient depot services to improve service efficiency. This research is descriptive qualitative. Data were obtained through document review, direct observation, interviews.  Waste identification uses Value Stream Mapping and Fishbone Diagram to determine the root causes of critical waste that occurs. The results showed that the highest percentage of value added was in the ordinary prescription service of 63.41%, the highest percentage of necessity but non-value added was in the prescription service that required drug distribution from the warehouse unit of 70.79%, and the highest non-value added was in the compounded prescription service process of 36.59%. By using lean hospital, it can be identified that many wastes occur including waiting, transportation, and defects. Increasing service efficiency at the Siti Hajar Mataram Islamic Hospital Outpatient depot can be done by minimizing non-value added activities.
Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region Afifah, Riza Nur; Wardani, Arief Kusuma; Kusuma, Tiara Mega
Sasambo Journal of Pharmacy Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v6i1.358

Abstract

Currently, there is a phenomenon that shows that many herbs consumed by the public contain medicinal chemicals (BKO). This study aims to identify the presence of BKO prednisone in rheumatic herbs and its levels. This study took five types of samples of rheumatic herbs in Magelang area with different brands, namely samples of herbs A, B, C, D and E, which are available in capsule and powder form. Identification of prednisone in rheumatic herbs was carried out using thin layer chromatography (TLC) method with silica gel GF254 as stationary phase and ethyl acetate: chloroform mixture (4:1) as mobile phase. Quantitative analysis was performed using UV-Vis spectrophotometry with a maximum wavelength of 238.5 nm. The rf value of prednisone standard 0.42 was obtained and quantitative analysis showed that the prednisone content in sample B in the first replication was 3.22%, in the second replication was 2.18%, in the third replication was 2.23%.
Physical characterization of paracetamol granule preparation using goroho banana starch as binder and disintegrant Mutmainnah, Mutmainnah; Abdullah, Abulkhair; Lewa, Sandra; Muhlis, S. Masitah
Sasambo Journal of Pharmacy Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v6i1.393

Abstract

The research aims to formulate Goroho banana starch (GBS) as a binding and disintegrating agent in paracetamol (PCT) granule preparations. PCT granules were made using GBS as a binding agent in 3 concentrations of 6, 8, and 10%, respectively. PCT granules using GBS as a disintegrating agent were made with three concentrations of 10, 15, and 20%, respectively. Paracetamol granules are made using the wet granulation method. Granules were evaluated using six parameters: flow rate, angle of repose, water content, bulk density, tapped density, and compressibility index. GBS as a binder showed good physical properties. F1 (6% GBS) showed a flow rate of 8.1 g/sec, an angle of repose of 22.9 degrees, a water content of 1.2%, and a compressibility index of 19.3%. F2 (8% GBS) shows a flow rate of 8.5 g/sec, an angle of repose of 18.5 degrees, a water content of 1.3%, and a compressibility index of 17.6%. F3 (10% GBS) shows a flow rate of 9.0 g/sec, an angle of repose of 21.5 degrees, a water content of 1.4%, and a compressibility index of 19.3%. 8% GBS showed the best physical properties as a binding agent for PCT granules. GBS as a disintegrating agent, shows excellent physical properties. F4 (10% GBS) shows a flow rate of 12.9 g/sec, an angle of repose of 17.0 degrees, a water content of 4.3%, and a compressibility index of 13.3%. F5 (15% GBS) shows a flow rate of 11.4 g/sec, an angle of repose of 18.0 degrees, a water content of 1.4%, and a compressibility index of 14.5%. F6 (20% GBS) shows a flow rate of 10.7 g/sec, an angle of repose of 23.0 degrees, a water content of 3.5%, and a compressibility index of 14.6%. 10% GBS showed the best physical properties as a disintegrants agent for PCT granules.
Formulasi serum antiaging nanopartikel emas dengan fraksi daun sirih hutan gambut Kalimantan (Piper aduncum) Gerung, Jenny Blessia; Sulistia, Tiya; Yulita, Elia; Sametri, Ni Wayan Septia; Rahman, Sudarman
Sasambo Journal of Pharmacy Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v6i1.401

Abstract

Free radicals are molecules with unpaired electrons that are reactive and unstable. Gold nanoparticles (AuNPs) have an antioxidant reducing Au3+ to Au+ which can stabilize free radicals. This research aims to characterize AuNPs, formulate and evaluate AuNPs antiaging serum with sirih hutan leaves fraction and antioxidant activity test. The research method used was maceration, sirih hutan leaves were extracted using 96% ethanol, fractionation using n-hexane, biosynthesis of AuNPs, formulation, and antioxidant activity using the DPPH method. The data analysis used One Way Anova test and post hoc Tukey (CI 95%). The research results showed that ethanol extract and n-hexane fraction were obtained at 132.5059 g and 18.3804 g respectively. Biosynthesis characterization of AuNPs have a particle size of 424.9 nm. Formulation and evaluation of AuNPs formulation were generally obtained according to SNI. The antioxidant activity of the formulation and vitamin C showed that the percentage of DPPH increased with increasing concentration, IC50 values of the formulaion and vitamin C showed 35.21 ± 0.95; 17.95 ± 0.34 ppm respectively. Based on One Way Anova test, there was significant difference in each concentration in the percentage of DPPH (p<0.05). and the formulation and vitamin C were classified as very strong antioxidants (IC50<50).

Page 8 of 10 | Total Record : 94

 6   7   8   9   10 

Filter by Year

2020 2025


Reset
Filter By Issues
All Issue Vol. 6 No. 2 (2025): September Vol. 6 No. 1 (2025): April Vol. 5 No. 2 (2024): September Vol. 5 No. 1 (2024): April Vol. 4 No. 2 (2023): September Vol. 4 No. 1 (2023): April Vol. 3 No. 2 (2022): September Vol. 3 No. 1 (2022): April Vol. 2 No. 2 (2021): September Vol. 2 No. 1 (2021): April Vol. 1 No. 2 (2020): September Vol. 1 No. 1 (2020): April More Issue