Garuda - Garba Rujukan Digital

Korelasi Kadar HbA1c dengan Kadar D-dimer pada Pasien Diabetes Melitus Tipe 2 Alamsyah, Lucky; Yulia, Dwi; Aprilia, Dinda
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1079

Abstrak Latar Belakang: Diabetes melitus tipe 2 (DM tipe 2) adalah penyakit gangguan metabolik yang ditandai dengan peningkatan gula darah akibat penurunan sekresi insulin oleh sel beta pankreas atau ganguan fungsi insulin (resistensi insulin) atau kedua-duanya. Peningkatan kadar HbA1c dan peningkatan kadar D-dimer merupakan dua kondisi pemeriksan hematologi yang bisa ditemukan dalam perjalanan penyakit DM tipe 2. Objektif: Penelitian ini bertujuan untuk mengetahui korelasi kadar Hba1c dengan kadar D-dimer pada pasien diabetes melitus tipe 2 . Metode: Penelitian ini merupakan analitik dengan pendekatan cross sectional pada data sekunder pasien diabetes melitus tipe 2 yang dilakukan pemeriksaan kadar HbA1c dan kadar D-dimer dengan alat POCT. Sampel penelitian ini adalah pasien yang didiagnosis DM tipe 2 dengan kadar HbA1c terkontrol (≤7 %) di Rumah Sakit Umum (RSU) Prof. Dr. M Ali Hanafiah Batu Sangkar, Kabupaten Tanah Datar sebanyak 20 sampel. Waktu penelitian periode November 2020–April 2021. Hasil: Penelitian diperoleh nilai rerata untuk kadar HbA1c pasien DM tipe 2 sebesar 5,925% dan kadar D-dimer sebesar 432 ng/mL. Analisis statistik uji korelasi Pearson menunjukkan tidak terdapat korelasi yang bermakna antara kadar HbA1c dengan kadar D-dimer (r=0,081; p=0,257). Kesimpulan: Pada penelitian ini dapat disimpulkan tidak ditemukan korelasi antara kadar HbA1c dengan kadar D-dimer pada diabetes melitus tipe 2. Kata kunci: D-dimer, Diabetes Melitus Tipe 2, HbA1c Abstract Background: Type 2 Diabetes is a metabolic disorder characterized by increased blood sugar due to decreased insulin secretion by pancreatic beta cells or insulin function disorders (insulin resistance) or both. Increased levels of HbA1c and increased levels of D-dimer are two conditions for hematological examination that can be found in the course of Type 2 diabetes. Objective: This study aims to determine whether there was a correlation between HbA1c levels and D-dimer levels in patients with Type 2 diabetes. Methods: This study was an analytic study with a cross sectional approach to secondary data for patients with type 2. 2 diabetes who were examined for HbA1c levels and D-dimer levels using POCT. The sample of this study were patients diagnosed with type 2 diabetes with controlled HbA1c levels (≤7 %) at Prof. Dr. M Ali Hanafiah Batu Sangkar, Tanah Datar Regency as many as 20 samples. The research period was November 2020 - April 2021. Results: Data analysis used univariate and bivariate analysis with the Pearson correlation test. Correlation was significant if p <0.05. The study obtained that the mean value for the HbA1c level of Type 2 diabetes patients was 5.925% and the D-dimer level was 432 ug / dL. The results of the bivariate analysis showed the relationship between HbA1c levels and D-dimer levels, the p value was 0.734 (> 0.05) and the correlation value (r) was 0.081. Conclusion: So it can be concluded that there is a weak correlation between HbA1c levels and D-dimer levels in patients with Type 2 diabetes.

Hubungan Tingkat Aktivitas Penyakit Lupus Eritematosus Sistemik dengan Derajat Gangguan Fungsi Ginjal pada Pasien Lupus Eritematosus Sistemik Nabila, Fathiya Sarah; Miro, Saptino; Effendi, Rinal; Almurdi, Almurdi; Yulia, Dwi; Putra, Syandrez Prima
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1103

Abstrak Latar Belakang: Evaluasi fungsi ginjal dan pemantauan aktivitas penyakit pada pasien lupus eritematosus sistemik (LES) diperlukan untuk mendeteksi penyakit LES secara dini. Penilaian aktivitas penyakit juga berperan penting dalam memandu pemberian terapi yang tepat agar memberikan hasil yang lebih baik. Objektif: Mengetahui hubungan antara tingkat aktivitas penyakit LES dengan derajat gangguan fungsi ginjal pada pasien LES. Metode: Penelitian ini merupakan penelitian analitik dengan pendekatan cross-sectional menggunakan data sekunder dari rekam medis pasien LES di Departemen Penyakit Dalam RSUP Dr. M. Djamil Padang. Teknik pengambilan sampel adalah consecutive sampling dengan total sampel 70 pasien LES. Analisis data dilakukan dengan menggunakan chi-squared test. Hasil: Terdapat 98,6% pasien berjenis kelamin perempuan, 48,9% pasien berada pada kelompok usia 17–25 tahun, rerata kadar serum kreatinin 1,756±3,3437 mg/dl, 65,7% pasien memiliki fungsi ginjal normal, 70% pasien memilliki tingkat aktivitas penyakit LES sedang, dan hasil uji statistik antara tingkat aktivitas penyakit LES dengan derajat gangguan fungsi ginjal pada pasien LES adalah menunjukkan nilai p=0,081. Kesimpulan: Mayoritas pasien berjenis kelamin perempuan, kelompok usia terbanyak yaitu usia 17 – 25 tahun, rerata kadar serum kreatinin 1,756±3,3437 mg/dl, mayoritas memiliki derajat fungsi ginjal yang normal, tingkat aktivitas penyakit LES sedang, dan tidak terdapat hubungan yang signifikan antara tingkat aktivitas penyakit LES dengan derajat gangguan fungsi ginjal pada pasien LES. Kata kunci: tingkat aktivitas penyakit, derajat gangguan fungsi ginjal, lupus eritematosus sistemik Abstract Background: Evaluation of kidney function and monitoring the disease activity in patients with systemic lupus erythematosus (SLE) are necessary for early detection of the SLE disease. Assessment of disease activity also plays an important role in providing a better therapy. Objective: This study aims to determine the relationship between SLE disease activity and the stages of kidney disease in SLE patients. Methods: This study is an analytical study with a cross-sectional approach using secondary data from the medical records of SLE patients in the Internal Medicine Department of Dr. M. Djamil Padang Hospital. The sampling technique is consecutive sampling with a total sample of 70 SLE patients. Data analysis was performed using chi-squared test. Results: There were 98.6% of the patients were female, 48.9% of the patients were in the age group of 17–25 years, the mean serum creatinine level was 1.756±3.3437 mg/dl, 65.7% of the patients had normal kidney function, 70% of the patients had a moderate level of LES disease activity, and the results of a statistical test between the level of activity of LES disease and the stages of kidney disease in SLE patients showed a value of p=0.081. Conclusion: The majority of patients were female, the largest age group was 17-25 years old, the average serum creatinine were 1,756±3,3437 mg/dl, majority of patients had a normal kidney function, had a moderate level of SLE disease activity, and there was no significant relationship between level of SLE disease activity and stages of kidney disease in SLE patients. Keyword: disease activity, stages of kidney disease, systemic lupus erythematosus

Profil Pasien Diabetes Melitus Tipe 2 dengan Ulkus Kaki Diabetik di RSUP Dr. M. Djamil Padang Tahun 2020-2021 Jannah, Lidya Raudhatul; Elvira, Dwitya; Noer, Mustafa; Decroli, Eva; Saputra, Deddy; Linosefa, Linosefa
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1114

Abstrak Latar Belakang: Ulkus kaki diabetik menjadi permasalahan di Indonesia karena sedikitnya tenaga kesehatan yang menggeluti ulkus kaki diabetik, sedikit pengetahuan masyarakat mengenai ulkus kaki diabetik, dan biaya penatalaksanaan yang besar. Objektif: Tujuan penelitian ini adalah untuk mengetahui profil pasien diabetes melitus tipe 2 dengan ulkus kaki diabetik di RSUP Dr.M. Djamil Padang. Metode: Penelitian ini merupakan penelitian deskriptif observatif dengan desain cross-sectional. Sampel penelitian adalah pasien dengan diagnosis ulkus kaki diabetik yang berobat di RSUP Dr.M. Djamil Padang periode 2020-2021. Pengambilan sampel menggunakan teknik total sampling dengan jumlah sebanyak 93 sampel. Data menggunakan jenis univariat dan penyajian data dalam bentuk tabel distribusi frekuensi. Hasil: Hasil penelitian menunjukkan pasien ulkus kaki diabetik paling banyak berada pada usia >55-65 tahun (41,9%), jenis kelamin perempuan (52,7%), tidak bekerja/ IRT (44,1%), tingkat pendidikan terakhir SLTA (55,9%). Derajat ulkus 5 (37,6%), lama rawatan 6-10 hari (40,9%), tekanan darah normal (43,1%). Hasil laboratorium menunjukkan keadaan anemia sedang (47,3%), hipoalbuminemia (96,8%), hiperglikemia (54,8%). Tatalaksana dengan pemberian kombinasi dua antibiotik (59,1%), terapi bedah debridemen (30,2%), kondisi pasien membaik saat dipulangkan (63,4%). Kesimpulan: Kesimpulan penelitian yaitu sebagian besar pasien ulkus kaki diabetik adalah perempuan lansia akhir dengan kondisi anemia, hipoalbuminemia, hiperglikemia. Tatalaksana yang umum diberikan adalah pemberian kombinasi dua antibiotik dan debridemen dengan luaran pasien membaik. Kata kunci: Diabetes melitus tipe 2, pasien ulkus kaki diabetik, profil Abstract Background: Diabetic foot ulcers are a problem in Indonesia because of the lack healthcare professional on diabetic foot ulcers, little public knowledge about diabetic foot ulcers, and high management costs. Objective: The purpose of this study was to determine the profile of type 2 DM patients with diabetic foot ulcers at RSUP Dr.M. Djamil Padang. Methods: This study was an observational descriptive with a cross-sectional design. The research sample was patients diagnosed with diabetic foot ulcers at RSUP Dr.M. Djamil Padang for the 2020-2021 period. The total sampling technique was used to collect a total of 93 samples. The collecting data was analyze by univariat and presented with frequency distribution tables. Results: The results of this study were the most diabetic foot ulcer patients were in the age group >55-65 years (41.9%), female (52.7%), unemployed/housewife (44.1%), and high school education (55.9%). The most ulcer grade 5 (37.6%), treatment duration was 6-10 days (40.9%) and normal blood pressure (43.1%). Laboratory results showed the conditions of moderate anemia (47.3%), hypoalbuminemia (96.8%), and hyperglycemia (54.8%). Management given was a two combination of antibiotics (59.1%), debridementt therapy (30.2%), the patient's condition improved when being discharged (63.4%). Conclusion: This study concluded that the majority of patients with diabetic foot ulcers were elderly women with anemia, hypoalbuminemia, and hyperglycemia. The most common management given was a combination of two antibiotics and debridementt, which resulted in improved patient outcomes. Patients who are at high risk are expected to be more aware of the appearance of symptoms and clinicians are expected to be able to manage patients comprehensively. Keyword : Diabetic foot ulcer patient, profile, type 2 diabetes mellitus

Gambaran Gejala Depresi pada Penderita Parkinson Disease di RSI Ibnu Sina Padang Mubarak, M. Dzaky; Syafrita, Yuliarni; Nurhayati, Nurhayati; Liza, Rini Gusya; Syahrul, Muhammad Zulfadli
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1153

Abstrak Latar Belakang: Penyakit Parkinson merupakan penyakit neurodegeneratif kronik progresif yang ditandai dengan hilangnya sel saraf (neuron) dopaminergik pada bagian substansia nigra. Pada Penyakit Parkinson dapat ditemukan gejala non motorik seperti gejala psikiatri terutama depresi. Depresi pada penderita parkinson memiliki dampak yang sangat besar pada kualitas hidup karena mengakibatkan penurunan kualitas hidup. Objektif: Penelitian ini bertujuan untuk mengetahui karakteristik penderita Penyakit Parkinson, distribusi terjadinya depresi pada parkinson, dan tingkatan depresi yang dialami pada penderita parkinson di RSI Ibnu Sina Padang. Metode: Penelitian ini adalah penelitian deskriptif dengan pendekatan kualitatif metode Cross Sectional dengan kuesioner Beck Depression Inventory. Pengambilan data penelitian berupa data primer dari semua penderita Parkinson yang berobat jalan pada bulan Maret 2023 hingga Mei 2023 di Poli Saraf RSI Ibnu Sina yang memenuhi kriteria dengan jumlah sampel 29 orang. Hasil: Hasil analisis data disajikan dalam bentuk tabel distribusi frekuensi. Hasil penelitian penderita Penyakit Parkinson lebih banyak ditemukan pada kelompok umur lansia dengan jenis kelamin perempuan dan paling banyak sudah tidak bekerja. Sebagian besar masih berstatus kawin dengan lama menderita sakit parkinson mayoritas selama ≥ 5 tahun dan terbanyak didapatkan pada stadium 3 Penyakit Parkinson. Kasimpulan: Mayoritas sebanyak 65,5% mengalami depresi dan paling banyak pada tingkat depresi sedang. Kata kunci: penyakit parkinson; depresi. Abstract Background: Parkinson's Disease is a progressive chronic neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra. In Parkinson's Disease, non-motor symptoms such as psychiatric symptoms, especially depression, can be found. Depression in people with Parkinson's has a very large impact on quality of life because it results in a decrease in quality of life. Objective: This study aims to determine the characteristics of patients with Parkinson's Disease, the distribution of depression in Parkinson's, and the level of depression experienced in patients with Parkinson's at RSI Ibnu Sina Padang. Methods: This research is a descriptive study with a qualitative approach with a cross sectional method using the Beck Depression Inventory questionnaire. Retrieval of research data in the form of primary data from all Parkinson's patients who were on outpatient treatment from March 2023 to May 2023 at the Ibnu Sina Hospital who met the criteria with a sample size of 29 people. Result: The results of this study found that people with Parkinson's Disease were mostly elderly age group, female, and most were not working. Most were still married, had suffered from Parkinson's disease for 5 years and more, and most found in stage 3 Parkinson's Disease. Conclusion: The majority as much as 65.5% experienced depression and most were at moderate levels of depression) Keywords: parkinson's disease; depression

Korelasi Indeks Massa Tubuh dengan Kadar Hemoglobin pada Lansia di Nagari Sumaniak Kabupaten Tanah Datar Ikhsan, Farid; Pertiwi, Dian; Reza, Mohamad
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1188

Abstrak Latar Belakang: Lanjut usia merupakan tahap akhir fase kehidupan yang mengalami perubahan dan penurunan kondisi fisiologis tubuh akibat proses degeneratif. Hal ini mengakibatkan meningkatnya masalah gizi pada lansia, salah satunya kurang gizi yang ditandai dengan rendahnya indeks massa tubuh. Indeks massa tubuh yang rendah merupakan salah satu faktor risiko terjadinya anemia. Objektif: Penelitian ini bertujuan untuk mengetahui apakah terdapat korelasi antara indeks massa tubuh dengan kadar hemoglobin pada lansia di Nagari Sumaniak, Kabupaten Tanah Datar. Metode: Penelitian ini merupakan penelitian analitik dengan desain penelitian cross sectional menggunakan data sekunder pada bulan oktober 2021 dengan subjek penelitian sebanyak 44 sampel. Metode penelitian menggunakan analisis data bivariat menggunakan uji Pearson correlation. Hasil: Hasil penelitian didapatkan kelompok lansia terbanyak berada pada lansia muda dengan jenis kelamin perempuan. Nilai rerata indeks massa tubuh sebesar 24,116 ±4,473 kg/m2, rerata kadar hemoglobin sebesar 12,55±1,961g/dL. Hasil analisis bivariat korelasi indeks massa tubuh dengan kadar hemoglobin didapatkan (r = 0,230; p = 0,133). Kesimpulan: Penelitian ini menunjukkan bahwa tidak terdapat korelasi bermakna antara indeks massa tubuh dengan kadar hemoglobin pada lansia di Nagari Sumaniak, Kabupaten Tanah Datar. Kata kunci: Indeks massa tubuh, Kadar hemoglobin, Lansia Abstract Background: Elderly is the final stage of life that experiences changes and decreases in the physiological condition of the body due to degenerative processes. It increased nutritional problems in elderly, which is undernutrition that characterized by a low body mass indeks. A low body mass index is a risk factor for anemia Objective: This study aims to determine whether there is a correlation between body mass index and hemoglobin levels in the elderly in Sumaniak Nagari, Tanah Datar Regency Methods: This study is an analytical study with a cross-sectional design using secondary data in october 2021 with 44 subjects. The study method uses bivariate data analysis using the Pearson correlation test. Results: The results of the study found that the most elderly group was young elderly with female gender. The average value of body mass index was 24.116 ± 4.473 kg/m2, the average hemoglobin level was 12.55 ± 1.961g/dL. The results of bivariate analysis of the correlation of body mass index with hemoglobin levels were obtained (r = 0.230; p = 0.133). Conclusion: The conclusions of this study indicate that there is no significant correlation between body mass index and hemoglobin levels in the elderly in Sumaniak Nagari, Tanah Datar Regency. Keyword: Body mass index, Hemoglobin level, Elderly

Hubungan Severitas Gambaran Radiologis Foto Toraks Pasien Covid-19 Dengan Peningkatan Kadar D-Dimer Randa, Ilham; Handayani, Tuti; Suharti, Netti
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1195

Abstrak Latar Belakang: Corona Virus Disease 2019 (COVID-19) adalah penyakit pneumonia yang disebabkan oleh infeksi SARS-CoV-2 yang dapat mengarah kepada badai sitokin yang menginduksi disregulasi koagulasi (ditandai dengan peningkatan kadar D-dimer) sehingga meningkatkan risiko terjadinya trombosis. Pemeriksaan foto toraks memiliki peranan dalam upaya pemeriksaan lini pertama karena penggunaannya yang mudah dan dapat diterapkan untuk memantau kelainan paru pada pasien COVID-19. Objektif: Penelitian ini bertujuan melihat hubungan severitas gambaran radiologis foto toraks pasien COVID-19 dengan peningkatan kadar D-dimer. Metode: Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional pada data sekunder pasien COVID-19 yang dilakukan pemeriksaan foto toraks dengan menggunakan skor Brixia dan kadar D-dimer di Rumah Sakit Dr. M. Djamil Padang terhadap 30 sampel. Analisis data menggunakan uji korelasi Pearson. Korelasi dinyatakan bermakna jika p<0,05. Hasil: Penelitian ini memperoleh nilai rerata untuk severitas gambaran radiologis foto toraks pasien COVID-19 sebesar 9,8±4,286 dan kadar D-dimer sebesar 1955±1065,041 µg/L. Hasil analisis bivariat menunjukkan hubungan severitas gambaran radiologis foto toraks dengan kadar D-dimer pada pasien COVID-19 (p=0,028) dan nilai korelasi (r) ialah 0,401. Kesimpulan: Kesimpulan yang didapat adalah terdapat hubungan dengan korelasi moderat antara severitas gambaran radiologis foto toraks dengan kadar D-dimer pada pasien COVID-19. Kata kunci: COVID-19, D-dimer, Foto Toraks Abstract Background: Corona Virus Disease 2019 (COVID-19) is a pneumonia caused by infection with SARS-CoV-2 that can lead to a cytokine storm that induces coagulation dysregulation (characterized by elevated D-dimer levels) thereby increasing the risk of thrombosis. X-ray examination has a role in first-line examination efforts because it is easy to use and can be applied to monitor lung abnormalities in COVID-19 patients. Objective: This study aims to see the relationship between the severity of the chest radiography of COVID-19 patients with increased levels of D-dimer. Methods: This study was an analytic study with a cross sectional approach to secondary data for patients with COVID-19 who were examined for chest X-ray with Brixia scores and D-dimer levels. The sample of this study were patients diagnosed with COVID-19 at Dr. M. Djamil Hospital, Padang as many as 30 samples. Data analysis used univariate and bivariate analysis with the Pearson correlation test. Correlation was significant if p<0,05. Results: The study obtained that the mean value for the chest X-ray scores of COVID-19 patients was 9,8±4,286 and the D-dimer level was 1955±1065,041 µg/L. The results showed that there was a significant relationship between chest X-ray scores and D-dimer levels, the p value was 0,028 and the correlation value (r) was 0,401. Conclusion: It is concluded that there is relationship with a moderate correlation between chest X-ray scores and D-dimer levels in patients with COVID-19.

Karakteristik Pasien Kusta dengan Reaksi dan Tanpa Reaksi Tahun 2018-2021 Di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang Dzakiyyah, Adzristi Zahrah; Rahmatini, Rahmatini; Gustia, Rina
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1204

Abstrak Latar Belakang: Kusta adalah salah satu penyakit menular yang dapat menyerang kulit dan saraf tepi dan disebabkan oleh Mycobacterium leprae. Kusta dapat ditularkan melalui cairan tubuh seperti dari mulut dan hidung serta terdapat kontak erat dan dekat dengan pasien kusta. Kusta dapat menyebabkan seseorang menderita suatu reaksi inflamasi yang disebut dengan reaksi kusta. Reaksi kusta jika tidak diobati secara adekuat dapat menyebabkan kecacatan atau disabilitas. Objektif: untuk mengetahui karakteristik pasien kusta dengan reaksi dan tanpa reaksi pada tahun 2018-2021 di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang Metode: Jenis penelitian ini adalah penelitian deskriptif. populasi penelitian ini adalah seluruh pasien yang terdiagnosis kusta dengan reaksi dan tanpa reaksi oleh klinisi di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang dengan jumlah sampel sebanyak 54 orang dari tahun 2018-2021. Hasil: Hasil penelitian didapatkan kasus kusta tanpa reksi terbanyak pada usia lansia, jenis kelamin laki-laki, tipe kusta MB, pemeriksaan BTA positif, dan tidak ada riwayat kontak erat dengan penderita kusta. Selain itu, kasus kusta dengan reaksi kusta terbanyak pada usia remaja, jenis kelamin laki-laki, tipe kusta MB, pemeriksaan BTA positif, tidak ada riwayat kontak erat dengan penderita kusta , tipe reaksi kusta ENL, dan waktu kejadian reaksi setelah MDT. Kesimpulan: Karakteristik pasien kusta dengan reaksi dan tanpa reaksi paling banyak pada kelompok usia remaja dan lansia, jenis kelamin laki-laki, tipe kusta MB, hasil pemeriksaan BTA positif, tidak ada riwayat kontak erat dengan penderita kusta, mengalami reaksi kusta tipe ENL, dan waktu kejadian reaksi setelah MDT. Abstract Background: Leprosy is and infectious disease caused by Mycobacterium leprae which affects the skin and peripheral nerves. Leprosy can caused a person to suffer from an inflammatory reaction called leprosy reaction. If not treated properly, leprosy reaction can lead to deformity or disability. Leprosy still exist in Indonesia and is still an unresolved problem until this day. Objective: This research aimed to determine the characteristics based on age, gender, majority, occupation, place of residence, complications, type of leprosy, AFB test result, history of close contact, type of leprosy reaction, and time of reaction of leprosy patients with and without reactions at the Dermatology and Venereology Polyclinic, RSUP Dr. M. Djamil Padang From 2018-2021. Methods: This study employed descriptive research. the population of this study consists all patients diagnosed leprosy with and without leprosy reaction by doctors with a total sampling methode obtained was 54 people from 2018-2021. Results: Of the 54 people sampled on this study this results showed that the majority of leprosy cases without reaction were found in elderly were 15 people (42,9%), male were 25 people (71,4%), MB type of leprosy were 25 people (71,4%), positive AFB test result were 17 people (48,5%), and patients with no history of close contact with leprosy patients were 31 people (88,6%). Additionally, the majority of leprosy cases with reactions were found in adolscent were 8 people (42,1%), male were 13 people (68,4%), MB type of leprosy, were 18 people (94,7%), positive AFB test result, were 13 people (68,4%), patients with no history of close contact with leprosy patients were 13 people (68,4%), patients with type 2 leprosy reaction (ENL) were 13 people (68,4%), and experiencing the reaction time after MDT were 9 people (47,4%). Conclusion: The majority of leprosy cases without reaction were found in elderly, male, MB type of leprosy, positive AFB test result, and patients with no history of close contact with leprosy patients. Additionally, the majority of leprosy cases with reactions were found in adolscent, male, MB type of leprosy, positive AFB test result, patients with no history of close contact with leprosy patients, patients with type 2 leprosy reaction (ENL), and experiencing the reaction time after MDT. Keyword: Leprosy, Leprosy Reactions, Without Reaction

Gambaran Faktor Risiko Hiperbilirubinemia Pada Neonatus yang Dirawat di Ruang Perinatologi RSUP Dr. M. Djamil Padang Fadhillah, Ilham Arief; Afdal, Afdal; Pertiwi, Dian; Masnadi, Nice Rachmawati; Rofinda, Zelly Dia; Handayani, Tuti
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1208

Abstrak Latar Belakang: Hiperbilirubinemia ditandai dengan adanya ikterus. Hiperbilirubinemia dibedakan menjadi dua jenis, yaitu hiperbilirubinemia fisiologis dan patologis. Hiperbilirubinemia pada neonatus perlu mendapat perhatian karena dapat menyebabkan neonatus mengalami bilirubin ensefalopati akut atau pada fase lanjut akan menyebabkan kernikterus Objektif: Penelitian ini bertujuan untuk mengetahui gambaran faktor risiko hiperbilirubinemia pada neonatus yang dirawat di perinatologi RSUP Dr. M. Djamil Padang Metode: Penelitian ini merupakan penelitian deskriptif retrospektif yang menggunakan data rekam medis neonatus dengan hiperbilirubinemia pada bulan Januari 2021 hingga Desember 2022 Hasil: Hasil penelitian ini didapatkan 58,6% neonatus dengan hiperbilirubinemia berjenis kelamin laki-laki, dan 35,7% masuk dalam kategori high risk. Kejadian faktor risiko hiperbilrubinemia pada neonatus adalah 35,6% dengan berat lahir rendah, 32,8% dengan inkompatibilitas darah, 32,8% dengan preterm, 21,4% dengan infeksi, 7,1% dengan breastfeeding jaundice, dan 1,4% dengan ibu diabetes melitus. Tidak ditemukan faktor risiko polisitemia pada neonatus yang hiperbilirubinemia. Kesimpulan. Pada penelitian ini didapatkan faktor risiko hiperbilirubinemia pada neonatus terbanyak adalah BBLR, diikuti oleh faktor risiko lainnya seperti inkompatibilitas darah, usia gestasi, infeksi, breastfeeding jaundice, dan ibu diabetes melitus Abstract Background: Hyperbilirubinemia is an increased level of bilirubin in the blood which is clinically characterized by icterus. There are various risk factors for hyperbilirubinemia in neonates so attention needs to be paid because it can cause neonates to experience acute bilirubin encephalopathy or in the advanced phase it can cause kernicterus. Objective: This study aims to describe the risk factors for hyperbilirubinemia in neonates treated at the neonatology department of RSUP Dr. M. Djamil Padang. Method: This research is a retrospective descriptive study using medical records of neonates with hyperbilirubinemia. This research was conducted at RSUP Dr. M. Djamil Padang in January 2021 – December 2022. In this study, 70 samples were obtained from neonates with a diagnosis of hyperbilirubinemia who met the inclusion criteria. Result: The results of this study founded that 35,7% of neonates with hyperbilirubinemia were included in the high risk category. 41% of neonates with hyperbilirubinemia are male. The risk factors for hyperbilirubinemia in neonates were 35.6% with low birth weight neonates, 32.8% with blood incompatibility, 32.8% with preterm, 21.4% with infections, 7.1% with breastfeeding jaundice, and 1.4% with diabetes mellitus. No risk factors for polycythemia were found in neonates with hyperbilirubinemia. Conclusion: The conclusion of this study is the most common risk factor for hyperbilirubinemia in neonates is LBW, followed by other risk factors such as blood incompatibility, gestational age, infection, breastfeeding jaundice, cholestasis, and maternal diabetes mellitus. Keyword: Neonates, hyperbilirubinemia, risk factors.

Pengaruh Suplementasi Zink Terhadap Mukositis Oral Terkait Radiasi Pasien Kanker Kepala dan Leher: Studi Kasus Dengan Pendekatan Berbasis Bukti Gultom, Yohana Elisabeth; Sinaga, Wina
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1253

Abstrak Latar Belakang: Mukositis oral merupakan efek samping radiasi kanker kepala leher yang paling sering, khususnya pada dosis radiasi lebih dari 30 Gray (Gy). Patofisiologi mukositis oral terkait radiasi dapat disebabkan oleh inflamasi dan reactive oxygen species (ROS) yang dihasilkan oleh radiasi pengion. Zink merupakan kofaktor dari sintesis, DNA, protein, polimerasi RNA, dan transkriptase terbalik sehingga memiliki kemampuan penyembuhan luka sekaligus meningkatkan pertumbuhan sel dan sistem imunitas tubuh. Objektif: Mengetahui efek pemberian suplementasi zink terhadap mukositis oral terkait radiasi pasien kanker kepala dan leher Metode: Pencarian literatur dilakukan dengan advanced searching pada Pubmed, Embase, dan Cochrane dengan kriteria eligibilitas yang ditentukan oleh penulis. Hasil: Terdapat 2 artikel yang relevan dengan pertanyaan klinis dan kriteria eligibilitas yang sudah ditetapkan, terdiri dari 1 Randomized Clinical Trial (RCT) dan 1 Systematic Review/Meta-Analysis (SR/MA). Penelitian RCT menyimpulkan suplementasi zink dapat bermanfaat dalam menangani mukositis oral dan penelitian SR/MA menyimpulkan bahwa tidak terdapat manfaat suplementasi zink terhadap mukositis oral pasien kanker kepala leher yang menjalani kemoradiasi. Kesimpulan: Berdasarkan tinjauan kritis yang telah dilakukan dalam studi RCT dan SR/MA, suplementasi zink tidak mempengaruhi mukositis oral terkait radiasi kanker kepala dan leher. Kata kunci: suplementasi zink, mukositis oral, orofaringeal mukositis, kanker kepala leher, radiasi, radioterapi Abstract Background: Oral mucositis is the most frequent radiation side effect of head and neck cancer, particularly at radiation doses greater than 30 Gy. The pathophysiology of radiation-related oral mucositis can be caused by inflammation and reactive oxygen species (ROS) generated by ionizing radiation. Zinc is a cofactor of synthesis, DNA, protein, RNA polymerization, and reverse transcriptase so that it has the ability to heal wounds while increasing cell growth and the body's immune system. Objective: To determine the effect of zinc supplementation on radiation-related oral mucositis in head and neck cancer patients. Methods: Literature search was conducted by advanced searching on Pubmed, Embase, and Cochrane with eligibility criteria determined by the author. Results: There were 2 articles relevant to the clinical question and eligibility criteria that had been set, consisting of 1 Randomized Clinical Trial (RCT) and 1 Systematic Review/Meta-Analysis (SR/MA). The RCT study concluded that zinc supplementation could be beneficial in managing oral mucositis and the SR/MA study concluded that there was no benefit of zinc supplementation on oral mucositis in head and neck cancer patients undergoing chemoradiation. Conclusion: Based on a critical review of RCT and SR/MA studies, zinc supplementation does not affect head and neck cancer radiation-related oral mucositis. Keywords: zinc supplementation, oral mucositis, oropharyngeal mucositis, head and neck cancer, radiation, radiotherapy

Perbedaan Prestasi belajar Pada Siswa dengan Adiksi, Adiksi Ringan, dan Non-Adiksi Game online di SMAN 15 Padang Astuti, Bunga; Liza, Rini Gusya; Kadri, Husnil
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1279

Abstrak Latar Belakang: Adiksi game online adalah kecanduan dalam memainkan game online dan paling banyak terjadi pada usia remaja, serta dapat mempengaruhi prestasi belajar. Objektif: Penelitian ini bertujuan untuk mengetahui adanya perbedaan prestasi belajar pada siswa dengan adiksi, adiksi ringan, dan non-adiksi game online di SMAN 15 Padang. Metode: Penelitian ini merupakan penelitian analitik komparatif kategorik tidak berpasangan dengan pendekatan cross sectional. Teknik yang digunakan dalam pengambilan sampel adalah total sampling. Hasil: Hasil penelitian menunjukkan 28,1% siswa mengalami adiksi game online dengan rerata prestasi belajar siswa pada kategori cukup. Hasil uji Kruskal-Wallis menunjukkan terdapat perbedaan yang bermakna pada prestasi belajar antara siswa adiksi, adiksi ringan, dan non-adiksi game online. Hasil Mann-Whitney U Test menunjukkan terdapat perbedaan bermakna pada prestasi belajar antara siswa adiksi ringan dengan non-adiksi game online, serta tidak terdapat perbedaan bermakna pada prestasi belajar antara siswa adiksi dengan adiksi ringan game online dan adiksi dengan non-adiksi game online. Kesimpulan: Kesimpulan penelitian ini adalah terdapat perbedaan yang bermakna pada prestasi belajar antara siswa adiksi, adiksi ringan, dan non-adiksi game online, terutama pada prestasi belajar antara siswa adiksi ringan dengan non-adiksi game online. Kata kunci: Adiksi, game online, prestasi belajar Abstract Background: Online game addiction is an addiction to playing online games and most often occurs at the age of teenagers, and can affect learning achievement. Objective: This study aims to determined the differences in learning achievement in students with addiction, mild addiction, and non-addiction to online games at SMAN 15 Padang. Methods: This research is an unpaired categorical comparative analytic with cross sectional approach. The technique used in sampling was total sampling. Results: The results showed that 28.1% of students were addicted to online games with an average student achievement in the moderate category. The results of the Kruskal-Wallis test showed a significant difference in learning achievement between students with addiction, mild addiction, and non-addiction to online games. The results of the Mann-Whitney U test showed a significant difference in learning achievement between students with mild addiction to online games and non-addicted to online games, and there was no significant difference in learning achievement between students with mild addiction to online games and addiction to non-addiction to online games. Conclusion: The conclusion of this study is that there are significant differences in learning achievement between students with addiction, mild addiction, and non-addiction to online games, especially on learning achievement between students with mild addiction to online games and non- addicted to online games. Keyword: Addiction, online games, learning achievement

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Fathiyyatul Khaira

Contact Email
fathiyyatul.khaira@gmail.com

Phone
+6285161910033

Journal Mail Official
jikesi.editorial@gmail.com

Editorial Address
Fakultas Kedokteran Universitas Andalas. Jln. Limau Manis, Pauh – Padang – Sumatera Barat. 25163.

Location
Kota padang,

Sumatera barat

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Fathiyyatul Khaira

Contact Email fathiyyatul.khaira@gmail.com

Phone +6285161910033

Journal Mail Official jikesi.editorial@gmail.com

Editorial Address Fakultas Kedokteran Universitas Andalas. Jln. Limau Manis, Pauh – Padang – Sumatera Barat. 25163.

Location Kota padang, Sumatera barat INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Fathiyyatul Khaira

Contact Email
fathiyyatul.khaira@gmail.com

Phone
+6285161910033

Journal Mail Official
jikesi.editorial@gmail.com

Editorial Address
Fakultas Kedokteran Universitas Andalas. Jln. Limau Manis, Pauh – Padang – Sumatera Barat. 25163.

Location
Kota padang,

Sumatera barat

INDONESIA