cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Bayu Brahma
Contact Email
journal.cancer@gmail.com
Phone
+628176389956
Journal Mail Official
admin@indonesianjournalofcancer.or.id
Editorial Address
National Cancer Center - Dharmais Cancer Hospital Research and Development Building, 3rd-floor Jl. Letjen S. Parman Kav. 84-86, Slipi West Jakarta
Location
Kota adm. jakarta barat,
Dki jakarta
INDONESIA
Indonesian Journal of Cancer
Published by National Cancer Center-Dharmais Cancer Hospital
ISSN : 19783744     EISSN : 23556811     DOI : https://www.doi.org/ 10.33371
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health
Indonesian Journal of Cancer is a peer-reviewed and open-access journal. This journal is published quarterly (in March, June, September, and December) by Dharmais Cancer Hospital - National Cancer Center. Submissions are reviewed under a broad scope of topics relevant to experimental and clinical cancer research. Articles are original research that needs to be disseminated and written in English. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted acceptance for publication. The journal publishes original research articles, case reports, and review articles under the following categories: cancer management, cancer prevention, cancer etiology, epidemiology, molecular oncology, cancer diagnosis and therapy, tumor pathology, surgical oncology, medical oncology, radiation oncology, interventional radiology, as well as early detection.
Arjuna Subject : Kedokteran - Onkologi
Articles 562 Documents
 53   54   55   56   57 
The Differential Gene Expression of Squamous Cell Carcinoma Versus Basal Cell Carcinoma Highlights Oxidative Phosphorylation As A Potential Factor in Metastasis: A Single-Cell Gene Expression Analysis Study Soekmadji, Peter Nugraha; Sanjaya, Ardo; Tangano, Justin Javier; Gunadi, Julia Windi
Indonesian Journal of Cancer Vol 19, No 2 (2025): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i2.1264

Abstract

Background: Nonmelanoma skin cancer (NMSC) can be classified into basal (BCC) and squamous cell carcinoma (SCC). Combined, they rank 5th among the highest incidences of cancer in the world. Despite their low mortality rate, metastasis remains a significant concern. Basal cell carcinoma grows slowly and rarely metastasizes, unlike squamous cell carcinoma, which usually metastasizes when left untreated. However, it is currently unknown what influences their metastatic potential.Method: This research uses single-cell RNA expression data from the Gene Expression Omnibus database. The data will be preprocessed, normalized, and integrated before differential expression and enrichment analyses. Additionally, the 5 most upregulated genes in basal cell carcinoma compared to squamous cell carcinoma and vice versa will be discussed.Results: 165 genes highly expressed in BCC were identified and enriched, with the most significant enrichment for genes promoting apoptosis. We also identified 143 genes highly expressed in SCC, which had the most significant enrichment for genes involved in oxidative phosphorylation. The top 5 upregulated genes in BCC were KRT17, CXCL8, RPS17, CCL20, and IER3, and in SCC were KRT1, LY6D, FABP5, S100A8, and KRT10.Conclusion: We identified differentially expressed genes, including those related to oxidative phosphorylation and cell multiplication, which may help explain the varying behaviors of these cancers, particularly the higher metastatic potential of SCC. However, further research is needed to examine the effects of oxidative phosphorylation on these cancer cells.
Descriptive Analysis of CT Scan Findings in Breast Cancer Patients with Bone Metastases in Universitas Andalas Hospital Radiotherapy Installation Yusriono, Irfan; Tri Septiana, Vina; Rafli, Rhandyka
Indonesian Journal of Cancer Vol 18, No 3 (2024): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i3.1097

Abstract

Background: Breast cancer is experiencing the most significant increase in cases among all cancers worldwide. Approximately 65% to 75 % of advanced breast cancer patients will experience bone metastases. CT scan is the most affordable and accessible method for evaluating bone metastases. This study aims to describe the characteristics of CT scan examination of bone metastases in breast cancer patients in the radiotherapy installation at Universitas Andalas Hospital from 2019 until 2021. Methods: A total of 51 patients with breast cancer who had bone metastases were included in this quantitative descriptive study, using a total sampling approach. The clinical data was taken from the medical records at the radiotherapy installation at Andalas University Hospital. The collected data was processed and analyzed using SPSS statistical software. Results: Based on the results, the mean age of patients was 49 years. The most histopathological type was invasive carcinoma mammae of no special type (57%). The most common site for bone metastases is osteo vertebrae (35%). Mixed lesions were the most frequent bone metastatic finding (51%), with fractures occurring in 27% of cases. Conclusions: The results of this study are breast cancer with bone metastases occurring on average at the age of 49 years, histopathological type the most is invasive carcinoma mammae of no special type. Breast cancer with bone metastases is most common in Osteo Vertebrae with mixed lesions as well as pathological fracture with a low percentage.
Effects of Post-Discharge Nutrition Tele-counselling on Cancer Patients with Chemotherapy Hadiyati, Fauzatun; Efiyanna, Rina; Saman, Saman; Supriastuti, Ratna; Wardhiasih, Ertin; Delimunthe, Tiara Nurlita; Wijayanti, Dwi Nurmaya; Fuadiyah, Zuhrotul
Indonesian Journal of Cancer Vol 19, No 1 (2025): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i1.1279

Abstract

Background: Cancer patients often experience a decrease in dietary intake and body weight as a result of chemotherapy side effects. This can worsen the condition of cancer patients who are at risk of malnutrition or those who have previously been diagnosed with malnutrition while in the hospital. This study aimed to determine the effect of post-discharge nutrition tele-counseling on changes in dietary intake, body weight, and body mass index of cancer patients receiving chemotherapy.Method: This study was quasi-experimental with a pre-test and post-test control group design conducted on 86 subjects. Respondents who met the inclusion criteria consisted of those who were adult cancer patients (aged 18 years), undergoing chemotherapy in an inpatient setting with a 3-week cycle, able to consume food orally or via NGT, able to weigh and measure height, had the WhatsApp application on their cell phone, and can participate in the study for 3 weeks. The statistical analysis used an independent t-test for changes in energy, protein, and carbohydrate intake. The changes in fat intake, body weight, and body mass index (BMI) were used in the Mann-Whitney test.Results: There were significant effects of nutrition tele-counseling by WhatsApp on increasing energy intake (P = 0.001), protein (P = 0.006), fat (P = 0.026), and carbohydrate (P = 0.002) compared to the control group, which had a decrease in dietary intake. Body weight (P ≤ 0.001) and BMI (P = 0.001) had increased compared to the control group, which had a decrease.Conclusions: Post-discharge nutrition tele-counseling could increase dietary intake, body weight, and BMI for cancer patients undergoing a 3-week cycle of chemotherapy.
Factor Associated with Mortality of Hospitalized Cancer Patients with COVID-19 Infection in Indonesia National Cancer Center Kurniawati, Sri Agustini; Sutandyo, Noorwati; Tadjoedin, Hilman; Pradipta, Jaka; Ismuha, Ratu Ralna; Ummah, Citra Dovina Khaira; Suryana, Kresna Dharma; Budi, Erwin
Indonesian Journal of Cancer Vol 18, No 2 (2024): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i2.1077

Abstract

Background: Cancer patients with COVID-19 are at risk of developing severe complications and outcomes due to immunosuppressive and inflammatory states. This study aims to provide insight into risk factors associated with mortality in this population. Methods: A retrospective cohort study was conducted at Dharmais National Cancer Center, Jakarta, Indonesia, from May 2020 to July 2021. Data were collected through electronic medical records using the consecutive sampling technique. The numerical and categorical data were then tested statistically. Results: The results showed 180 cancer patients with COVID-19 were hospitalized at Dharmais National Cancer Center. Among the patients, 114 patients survived, and 66 patients deceased. Across all risk factors analyzed to mortality, patients with Diabetes Mellitus (OR 0.41;0.22-0.77, p-value 0.05) and high level of D-dimer (OR 2.00;1.06-3.79, P-value 0.05) have a higher risk in mortality. The Results showed that survived patients have lower D-dimer levels (2010 ng/L) and deceased patients have higher D-dimer levels (3264 ng/L) with P-value 0.05. Conclusion: High D-dimer levels and diabetes are risk factors significantly associated with mortality in hospitalized cancer patients with COVID-19 Infection.
Incidence and Characteristics of Skin Cancer Patients at Dr. Mohammad Hoesin General Hospital, Palembang Hardianto, Alvendro; Qodir, Nur; Roflin, Eddy; Indra, Bima
Indonesian Journal of Cancer Vol 19, No 1 (2025): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i1.1280

Abstract

Background: Breast-related new skin cancer cases have increased annually over the past decade. Current data on new skin cancer cases is essential as a preliminary step in preventing and reducing the incidence of new cases. This study aims to determine the incidence and characteristics of skin cancer patients at Dr. Mohammad Hoesin General Hospital, Palembang, from 2019 to 2021.Methods: This observational descriptive study employed a cross-sectional design using total sampling. Data were obtained from the medical records of skin cancer patients at Dr. Mohammad Hoesin General Hospital between January 2019 and December 2021. The variables analyzed included demographic characteristics (age, gender, occupation, education, marital status, and residence), cancer type, cancer stage, and tumor location. The data were analyzed using descriptive statistics to determine the frequency and distribution of each variable. Results: The incidence and characteristics of skin cancer at Dr. Mohammad Hoesin General Hospital were recorded in 38 patients. Basal cell carcinoma was the most common type, accounting for 44.74% of cases. Most patients were aged 45-64 years (52.6%), unemployed or housewives (65.8%), female (65.8%), had completed high school (44.7%), were married (89.5%), and resided outside Palembang (55.3%). Most cases were diagnosed at stage I (44.7%) and were primarily located in the head and neck region (76.3%). Early-stage diagnosis is associated with better survival rates, while advanced-stage cancers, are more aggressive and require prompt treatment for improved survival outcomes. Understanding these factors is crucial for optimizing patient management and resource allocation.Conclusions: The study shows basal cell carcinoma as the most common skin cancer at Dr. Mohammad Hoesin General Hospital, with a higher incidence in females, especially those aged 45–64, unemployed or housewives, married, and living outside Palembang. Most cases were diagnosed early and located in the head and neck
HALP and PNI Score as Predictors of Nutritional Status in the Incidence of Incisional Hernia after Laparotomy in Colorectal Cancer Patients: A Case-Control Study Nurasti, Wawan Suci; Handaya, Adeodatus Yuda; Barmawi, Agus; Anwar, Sumadi Lukman
Indonesian Journal of Cancer Vol 18, No 3 (2024): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i3.1215

Abstract

Background: Colorectal cancer ranks as the third most common cancer in the world. If patients can still be resected, surgical therapy is carried out. An incisional hernia is one of the complications after laparotomy surgery. Nutritional status can influence the incidence of incisional hernias after laparotomy. Colorectal cancer patients must have their nutritional status assessed using a simple scoring. This research aims to evaluate Hemoglobin, Albumin, Lymphocyte, Platelet (HALP) and Prognostic Nutritional Index (PNI) scores as a predictor of incisional hernia after laparotomy surgery in colorectal cancer patients at Dr. Sardjito General Hospital, Yogyakarta. Methods: This study uses a case-control study design which consisted of two groups, a case group of colorectal cancer patients with incisional hernias after laparotomy surgery and a control group of colorectal cancer patients without incisional hernias. The independent variable was nutritional status which was assessed by HALP and PNI score, and the dependent variable was incisional hernia. This research by taking data from laboratory patients at Dr. Sardjito General Hospital, Yogyakarta. For multivariate analysis, a logistic regression test was used with a significance value of p 0.05. Results: There is a relationship between the stage of cancer and the comorbid diabetes mellitus with the incidence of incisional hernias after laparotomy, this can be seen in the results of the chi-square test. Advanced stage has an OR of 13 (P=.001; OR=13; 95% CI 3.551-47.597), while comorbid diabetes mellitus has an OR of 6.571 (P=.002; OR=6.571; 95% CI 2.109-20.479). However, there is no correlation between the HALP and PNI score with the incidence of incisional hernia after laparotomy. The multivariate analysis results in HALP score have a significant correlation between the nutritional status and the incidence of incisional hernia with OR=17.981 (p= 0.037 OR=17; 95% CI 1.198-269.803). Conclusions: The HALP score can be used as a screening predictor in the incidence of incisional hernia after laparotomy for colorectal cancer patients.
The Characteristics of Sociodemography, Histopathologic Features, Stage, and Management of Ovarian Cancer in Dr. Ramelan Navy Hospital Surabaya Rahmalia, Karina; Sudiarta, Ketut Edy; Setianingsih, Herin; Diarsvitri, Wienta
Indonesian Journal of Cancer Vol 18, No 2 (2024): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i2.1050

Abstract

Background: Ovarian cancer is considered a silent killer disease, mainly due to the late diagnosis. It is often diagnosed at an advanced stage, thus increasing the mortality rate. Ovarian cancer can happen to any age, with different characteristics according to the age group, the most often being the epithelial type.Methods: This research is a descriptive study with a quantitative method. This study aims to determine the characteristics and histopathological features of ovarian cancer in Dr. Ramelan Navy Hospital from January 2019 to December 2021. There were 155 samples out of 635 patients, with the information acquired through medical records.Results: The highest incidence of ovarian cancer occurs in the 40-60-year-old group at 52.9%. Among all participants, 85.8% of patients were not employed. Of most histopathological features in epithelial ovarian cancer, 34.8% were the serous carcinoma subtype. The majority of these cases were diagnosed at stage IIIC at 21.3%, and the most prevalent treatment for ovarian cancer was surgery and chemotherapy at 49.7%.Conclusions: The most common type of ovarian cancer is epithelial ovarian cancer, a subtype of serous carcinoma, with histopathological features of round nucleated anaptic cells, prominent nucleoli, forming acini, papillae, and thin connective tissue stroma. 
Factors Causing Diagnostic Delay and Treatment Delay Patient Breast Cancer in Universitas Andalas Hospital Alfaini, Fadhli; Rafli, Rhandyka; Oktara, Meta Zulyati
Indonesian Journal of Cancer Vol 18, No 3 (2024): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i3.1072

Abstract

Background: Diagnostic and treatment delays are contributing factors to the increasing incidence and mortality of breast cancer worldwide, including in Indonesia. The study aimed to discern the underlying factors contributing to diagnostic and treatment delays in breast cancer patients.  Methods: This study uses a descriptive method. Primary data collection through guided interviews using questionnaires to 40 breast cancer patients who underwent treatment. This study was conducted at the University Andalas Hospital from January 2022 to September 2022. Results: The breast cancer diagnostic delay is caused by poor knowledge (52.5%), negative attitudes and behaviors (57.5%), a strong fear of breast cancer (55.0%), good social support (65.0%), and the impact of the Coronavirus Disease 2019 (COVID-19) pandemic on breast cancer examination (75.0%). The breast cancer treatment delay is due to poor knowledge (52.5%), positive attitudes and behaviors (52.5%), a strong fear of breast cancer treatment (55.0%), good social support (67.5%), the impact of the COVID-19 pandemic on breast cancer treatment (75.0%). Conclusions: The overview of factors causing diagnostic delay and treatment delays in breast cancer patients is dominated by negative categories, particularly in terms of knowledge, attitudes and behaviors, fear, and the COVID-19 pandemic. Only social support is positive, falling into a good category, as well as the attitudes and behaviors related to breast cancer treatment, which are also categorized as good.
The Role of Acupuncture in Cancer Care: From Symptom Alleviation to Tumor Suppression: A Narrative Review Setiawan, Natasha; Mihardja, Hasan
Indonesian Journal of Cancer Vol 18, No 1 (2024): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i1.1111

Abstract

Background: Cancer remains a prevalent disease worldwide, a leading cause of mortality worldwide. Cancer presents numerous treatment challenges, from determining the efficacy of treatment modalities to managing a wide array of therapy-related side effects. Acupuncture, a traditional form of therapy, is increasingly being recognized for its potential in alleviating cancerrelated symptoms and treatment side effects. Acupuncture functions by targeting specific points in the body, leading to the modulation of neurotransmitters within the central nervous system. Research has shown that acupuncture can alleviate cancer-related symptoms that range from chemotherapy-induced nausea and vomiting, pain, and several other side effects. This mechanism has been linked to the reduction of inflammation and alleviation of pain, proving beneficial to cancer patients. Its effectiveness varies across different types of cancers. As cancer research continues to grow, so does the research on genetic role in cancer.  Methods: This narrative review assessed the influence of acupuncture on gene expression regulation in cancer. We searched three databases and found eight studies indicating that acupuncture plays a role in cancer management through the regulation of gene expression.  Results: Studies have suggested acupuncture’s potential in reducing tumor growth in different types of cancer, such as osteosarcoma, breast cancer, and colorectal cancer, possibly through mechanisms involving gene regulation and inflammatory cytokines.  Conclusions: While genetic factors can influence individual responses to acupuncture, the therapy is generally considered safe and has been accepted by a significant percentage of cancer patients and caregivers.
Profile of Rectal Cancer Patients Undergoing Radiation Therapy in Dr. Hasan Sadikin General Hospital From 2016 Until 2021 Kurniadi, Nathanael; Utama, Marhendra Satria; Purnama, Andriana
Indonesian Journal of Cancer Vol 18, No 1 (2024): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i1.1020

Abstract

Background: Rectal cancer is a type of malignancy that occurs in the rectum. One of the many options of therapy for rectal cancer includes radiotherapy. This research was done to learn about the profile of rectal cancer patients undergoing radiation therapy at Dr. Hasan Sadikin General Hospital from 2016 until 2021. Methods:  A retrospective descriptive study that uses data obtained from patient’s medical records from Dr. Hasan Sadikin General Hospital from 2016 until 2021. The sampling technique used is total sampling from 109 data of rectal cancer patients who underwent radiation therapy in Dr. Hasan Sadikin from 2016 until 2021 Results: : From all 109 rectal cancer patients undergoing radiotherapy, the most often patients found have the age group of 40-49 years old (28.4%), females (50.5%), are mostly found from Priangan area (65.1%), have the chief complaint of a problem with defecating (51.3%), at stage III (36.7%), and have previously received operative management from their previous institutions (42.2%). The patients are mostly undergoing radiotherapy for curative indications (68.8%) and most have a waiting time of more than six weeks before obtaining radiotherapy (61.4%). Conclusions:  Cases of rectal cancer in radiotherapy patients in Dr. Hasan Sadikin General Hospital from the year 2016 to 2021 are seldom compared to other types of cancer and mostly occur in patients aged 40 to 49 years old. Most of the patients come for a curative reason and must wait for more than six weeks before obtaining radiation therapy. Further research may be performed to find the most effective method of giving curative radiotherapy as well as the time given in the hope of making radiotherapy planning more effective in the future.

Page 56 of 57 | Total Record : 562

 53   54   55   56   57 

Filter by Year

2007 2025


Reset
Filter By Issues
All Issue Vol 19, No 3 (2025): September Vol 19, No 2 (2025): June Vol 19, No 1 (2025): March Vol 18, No 4 (2024): December Vol 18, No 3 (2024): September Vol 18, No 2 (2024): June Vol 18, No 1 (2024): March Vol 17, No 4 (2023): December Vol 17, No 3 (2023): September Vol 17, No 2 (2023): June Vol 17, No 1 (2023): March Vol 16, No 4 (2022): December Vol 16, No 3 (2022): September Vol 16, No 2 (2022): June Vol 16, No 1 (2022): March Vol 15, No 4 (2021): December Vol 15, No 3 (2021): September Vol 15, No 2 (2021): June Vol 15, No 1 (2021): March Vol 14, No 4 (2020): December Vol 14, No 3 (2020): September Vol 14, No 2 (2020): June Vol 14, No 1 (2020): March Vol 13, No 4 (2019): December Vol 13, No 3 (2019): September Vol 13, No 2 (2019): June Vol 13, No 1 (2019): March Vol 12, No 4 (2018): October-December Vol 12, No 3 (2018): July-September Vol 12, No 2 (2018): April-June Vol 12, No 1 (2018): Jan - Mar Vol 11, No 4 (2017): October- December 2017 Vol 11, No 3 (2017): July - September 2017 Vol 11, No 2 (2017): April - June Vol 11, No 1 (2017): Jan-Mar Vol 10, No 4 (2016): October - December 2016 Vol 10, No 3 (2016): July - September 2016 Vol 10, No 2 (2016): April - June 2016 Vol 10, No 1 (2016): Jan - Mar 2016 Vol 9, No 4 (2015): Okt - Des 2015 Vol 9, No 3 (2015): Jul - Sept 2015 Vol 9, No 2 (2015): April-Juni 2015 Vol 9, No 1 (2015): Jan - Mar 2015 Vol 8, No 4 (2014): Oct - Dec 2014 Vol 8, No 3 (2014): Jul - Sep 2014 Vol 8, No 2 (2014): April-Juni 2014 Vol 8, No 1 (2014): Jan - Mar 2014 Vol 7, No 4 (2013): Oct - Dec 2013 Vol 7, No 3 (2013): Jul - Sep 2013 Vol 7, No 2 (2013): Apr - Jun 2013 Vol 7, No 1 (2013): Jan - Mar 2013 Vol 6, No 4 (2012): Oct - Dec 2012 Vol 6, No 3 (2012): Jul - Sep 2012 Vol 6, No 2 (2012): Apr - Jun 2012 Vol 6, No 1 (2012): Jan - Mar 2012 Vol 5, No 4 (2011): Oct - Dec 2011 Vol 5, No 3 (2011): Jul - Sep 2011 Vol 5, No 2 (2011): Apr - Jun 2011 Vol 5, No 1 (2011): Jan - Mar 2011 Vol 4, No 4 (2010): Oct - Dec 2010 Vol 4, No 3 (2010): Jul - Sep 2010 Vol 4, No 2 (2010): Apr - Jun 2010 Vol 4, No 1 (2010): Jan - Mar 2010 Vol 3, No 4 (2009): Oct - Dec 2009 Vol 3, No 3 (2009): Jul - Sep 2009 Vol 3, No 2 (2009): Apr - Jun 2009 Vol 3, No 1 (2009): Jan - Mar 2009 Vol 2, No 4 (2008): Oct - Dec 2008 Vol 2, No 3 (2008): Jul - Sep 2008 Vol 2, No 2 (2008): Apr - Jun 2008 Vol 2, No 1 (2008): Jan - Mar 2008 Vol 1, No 4 (2007): Oct - Dec 2007 Vol 1, No 3 (2007): Jul - Sep 2007 Vol 1, No 2 (2007): Apr - Jun 2007 Vol 1, No 1 (2007): Jan - Mar 2007 More Issue