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Hang Tuah Medical Journal
Published by Universitas Hang Tuah
ISSN : 16931238     EISSN : 25984861     DOI : https://doi.org/10.30649/htmj.v19i2
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Hang Tuah Medical Journal: is published by Faculty of medicine, Universitas Hang Tuah with p-ISSN: 1693-1238 e-ISSN: 2598-4861. Its disciplinary focus is medical science and speciality in bio marine science. Hang Tuah Medical Journal is published in English and Indonesia for May and November. Each 90-100 page edition contains between nine and eleven scientific articles on research, case reports and study literature. Contributors of Hang Tuah Medical Journal included: medical researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries. Hang Tuah Medical Journal as the open-access journal has been indexed by SINTA-Science and Technology Index, Garuda, Google scholar Hang Tuah Medical journal has been certificated as a Scientific Journal by Sinta (Science and Technology Index) S5 . valid until Volume 17 No.1, 2017.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 161 Documents
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Hubungan Kadar HbA1c pada Pasien Diabetes Melitus Tipe II dengan Kejadian Azotemia di Rumah Sakit Angkatan Laut Dr. Ramelan Surabaya VIOLITA PUTRI MURSANDI; SUWARNO; MOHAMMAD FATHI ILMAWAN
HANG TUAH MEDICAL JOURNAL Vol 18 No 1 (2020): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract

ABSTRACT Background : Diabetes mellitus is chronic condition of elevated blood sugar levels, which can lead to complication due to uncontrolled sugar levels which is measured by HbA1c level parameters, affecting microvascular conditions, one of which is in the kidneys, which results in decreased kidney function characterized by elevated creatinine serum and BUN levels called by azotemia. In 2011 as many as 49.677 individuals began treatment for kidney failure which caused by diabetes, and around 228.934 people with various ages within kidney failer due to diabetes do dialysis and kidney transplantation. Methods : This observational analytic study was conducted by using cross sectional study design, by taking secondary data from the medical record files of diabetes mellitus type II patients who are doing outpatient care at the Diabetes Clinic Dr. Ramelan Naval Hospital Surabaya. Patients with a diagnosis of diabetes mellitus type II for at least five years will be the inclusion criteria of case samples. Bivariate analysis was performed using Spearman Correlation Test. Results : The results also showed that there were 19 people without azotemia and 21 people with azotemia. Blood sugar control which one of risk factor of azotemia by measuring HbA1c levels results 6 people with HbA1c <7; 21 people with HbA1c 7.19.0; and 13 people with HbA1c> 9.0. Spearman correlation test showed a significant value of p=0,512 with correlation coefficient 0.107. Conclusion: there is no relationship between HbA1c levels of type II diabetes mellitus patients with the incidence of azotemia
Efek Analgesik Ekstrak Etanolik Daun Mangrove Api-Api Putih (Avicennia alba) terhadap Mencit (Mus musculus L.) Jantan yang Diinduksi Asam Asetat 0,7% ANDREW THEO WILLIAM CHRIS PURMATA; LESTARI DEWI; CHOESNAN EFFENDI
HANG TUAH MEDICAL JOURNAL Vol 18 No 1 (2020): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract

ABSTRACT Background : Avicennia alba or known as mangrove api-api putih is a type of mangrove species which has many benefits and often to be used by the local Indonesians as traditional medicine. The alcaloid and flavonoid substances derived from Avicennia alba leaves could inhibit pain. This study aims to determine the analgesic effect of Avicennia alba leaves extract in male mice (Mus musculus L.) induced by acetic acid 0,7%. Method :25 mice were divided into 5 groups that were given different therapies. The therapy are 10 mL/kg bw of water, 150 mg/kg bw of acetosal, 250 mg/kg bw; 500mg/kg bw; 1000 mg/kg bw of Avicennia alba leaves extract. 0,7% acetic acid with dose of 10 mL/kg bw is given to each subject intraperitoneally 30 minutes after the therapy to induce pain. The pain is manifested as writhes in mice, the writhes then are counted repeatedly each 10 minutes for 30 minutes. Result:: mean of writhes in group treated with Avicennia alba leaves extract in 250 mg/kg bw and 500 mg/kg bw with each value 6,20 and 9,40 are less than mean of writhes in negative control group with value 31,40. %inhibition of Avicennia alba leaves extract with dose of 250 mg/kg bw and 500 mg/kg bw respectively are 80,25% and 70,06%. Conclusion : Avicennia alba leaves extract in 250 mg/kg bw and 500 mg/kg bw dosage showed analgesic effect in male mice (Mus musculus L.) induced with 0,7% acetic acid.
PENGARUH HbA1c TERHADAP SINDROMA MATA KERING PADA PASIEN DIABETES MELLITUS DI SURABAYA NI WAYAN WIWIN OKTORI; VARIDIANTO YUDO TJAHJONO; SRI ARIANI
HANG TUAH MEDICAL JOURNAL Vol 18 No 1 (2020): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract

Abstract Background: Diabetes mellitus is a public health problem experienced by many countries and becomes a serious problem, affecting health in the world. Various complications of DM related to the surface of the eye is dry eye syndrome. Dry eye syndrome is an eye disorder with symptoms of discomfort, pain, dryness and foreign body sensation in the eye. The level of glycosylated hemoglobin (HbA1c) is one indicator of DM and it is stated that the prevalence of dry eye syndrome is significantly higher in DM sufferers than in healthy individuals. The Aim of this study to know the effect of HbA1c on dry eye syndrome in patients with diabetes mellitus Method :. This study used a cross sectional method and the sampling method used was purposive sampling. Samples taken as many as 34 people are patients with diabetes mellitus aged 18-55 years who have HbA1c results seen from medical records at the Public Health Center Jagir Surabaya. The research data was taken using the Dry Eye Questionnaire (DEQ), interviews and Schirmer Test I. The research data was then analyzed using a contingency test. Result: The significance value of the HbA1c test with the Schirmer I Test showed p = 0.026; that’s means a significant effect between HbA1c levels on dry eye syndrome with the Schirmer I Test and the significance value of the HbA1c test with the DEQ questionnaire shows p <0.001; that’s means a significant effect between HbA1c levels on dry eye syndrome and DEQ questionnaire, performed on patients with diabetes mellitus in Jagir Health Center, Surabaya City Conclusion: There is an influence of HbA1c levels on dry eye syndrome
The Efficacy of Aedes aegypti Natural Larvicide Gained from Averrhoa bilimbi and Averrhoa carambola GIANINA ANGELIA SANTOSO; NATHANIA DISA ARIESTA ANDRIANI; HEBERT ADRIANTO
HANG TUAH MEDICAL JOURNAL Vol 18 No 1 (2020): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract

Abstract Background: Dengue Hemorrhagic Fever (DHF) is an endemic disease transmitted by Aedes aegypti which is supposed to be demolished by using the Larvicidal activity. However, there are some Ae. aegypti larvae which are found resistant against the temephos in some provinces in Indonesia. Thus, this has been one of the biggest concern of The Ministry of Health Republic Indonesia. Apart from the resistance effect caused, temephos has been reported causing a water pollution which triggers the decreasing standard of human health and immune system. These factors have created a need for search of a new and natural larvicide, which one of it can be gained from Averrhoa. This research is aimed at comparing the effectiveness between the extract Averrhoa bilimbi and Averrhoa carambola towards the Ae. aegypti larvae’s mortality. Method: An experimental laboratory research involving the design of post test-only control group. Twenty five larvae Ae. aegypti third instar were carried out at 5 different concentrations (0%, 1%, 1.6%, 2.6%, 3.4%, and 4%). The larva demolition is counted within 24 hours. The mortality data is then analysed with the probit analysis. Results: The extract of Averrhoa bilimbi and Averrhoa carambola can cause the mortality of the Ae. aegypti larvae. LC99 24 hours from Averrhoa bilimbi was recorded = 1.47% (1.20-2.04%), whereas LC99 24 hours was recorded from Averrhoa carambola = 8.96% (7.59-11.31%). The major loses appeared is the stretchy necks and injured appendices. The bioactive substances which are predicted to be the causes of the mortality in this research are saponin glycoside and flavonoid. Conclusion: The extract of Averrhoa bilimbi produces the strongest and the most effective larvicide which will be potentially developed as a new larvicide
DAYA HAMBAT DAN DAYA BUNUH EKSTRAK SERBUK BATANG SIWAK TERHADAP BAKTERI STREPTOCOCCUS PYOGENES NUGROHO EKO WIRAWAN BUDIANTO
HANG TUAH MEDICAL JOURNAL Vol 18 No 1 (2020): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract

ABSTRACT Background: One of the most growing plants in the Middle East is siwak, which was used to clean teeth. Currently, we have toothpaste that contains siwak as its active ingredient. Previous studies have shown that siwak has anti-bacterial power on Streptococcus faecalis and Streptococcus mutans. This study aims to prove whether the extract of siwak stem powder can be used to inhibit the growth of Streptococcus pyogenes bacteria, one of which can cause pharyngitis. Methods: In this study, the Only Post Test Control Group Design method was used. This study used 24 samples divided into four repetitions (replications) and six treatments. The research used siwak stem extract at a concentration of 100%, 75%, 50% and 25%. Results: It was found that the zone of inhibition of siwak stem powder extract against the growth of Streptococus pyogenes. The mean inhibition zone of the concentrations of 100%, 75%, 50% and 25% was 10.77 mm, 9.77 mm, 8.47 mm and 0 mm. The results of statistical tests showed that the diameter of the bacterial inhibition zone in the K1 group was significantly different against K3, K4, K5, K6, and between the K2 groups against K3, K4, K5, K6 with Pvalue, <0.05. There is no significant difference between K1 and K2 and K3 with K4 and K4 with K5, because the value of Pvalue is> 0.05. Conclusion: The higher the concentration of siwak extract, the wider the inhibition zone will be. At a concentration of 50% the ethanol extract of the siwak stem powder can provide inhibitory power on the growth of the Streptcicoccus pyogenes bacteria. At concentrations of 75% and 100% the inhibition power also increased. At a concentration of 100% it was statistically significant different from the inhibition of amoxicillin.
Potensi Kejadian Burnout pada Mahasiswa Kedokteran di Masa Pandemi Covid-19 AHMAD FIRDAUS; NURMA YULIYANASARI; GINA NOOR DJALILLAH; MUHAMMAD REZA UTAMA
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v18i2.117

Abstract

Abstract Covid-19 pandemic has caused universal psychosocial repercussions and mass hysteria among the society and various sectors, including education sector. The online learning or distance learning applied during the pandemic has worsened the stress experienced by medical students. The stress level increased due to gaps in access to learning and excessive assignments given without considering students’ cognitive, affective, and psychomotor domains. Continuous academic stress in the long term would bring negative impacts, leading to lower learning motivation and burnout syndrome. The quality of social relationship has been known to significantly affect anxiety level. Therefore, cooperation from family, community, academic institutions, and government agencies in providing social attention and support is needed. In addition, intrinsic preventions through the improvement of lifestyle, health-related behaviour, religious approaches (The Psychology of Religion), motivation, and self-resilience are also important to avoid burnout syndrome among medical students. This study was conducted to propose insights that are expected helpful in anticipating, preventing and minimizing the occurrence of burnout syndrome which would lead to maladaptive behaviours among medical students
Pengaruh Ekstrak Jahe Merah (Zingiber Officinale.) Terhadap Pertumbuhan Bakteri Shigella Dysentriae NI KADEK SINTA DWI CHRISMASYANTI; KADEK DENIK SUASTINI; NI LUH SURAS AMOURA CAWIS; NI WAYAN SUCINDRA DEWI
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v18i2.119

Abstract

Abstract Diarrheal disease in Indonesia is still a high health problem for its morbidity and mortality rates. Diarrhea is still a cause of death in children under 5 years, amounting to 25.2%. Diarrhea morbidity in Indonesia during 2015 reached 6,897,463 and diarrhea that had been handled reached 2,544,084 or as much as 36.9%. The most important and most common cause of diarrhea in developing countries is Shigella, especially Shigella dysentriae and Shigella boydi which causes diarrhea with dysentery. One natural ingredient that has the potential to treat Shigella Dysentriae bacteria is ginger (Zingiber officinale). The ginger plant itself is very abundant in Indonesia. The antibacterial effect against Shigella dysenteriae is due to the active ingredient in ginger, namely gingerol, which inhibits the antibacterial activity of phenolics, flavonoids with an inhibitory mechanism by denaturing bacterial cell wall proteins.
Hubungan Antara Hs-Crp Dengan Derajat Keparahan Lesi Angiografi Berdasarkan Gensini Scoring Pada Penderita Stable Angina di Surabaya ANTOK WICAKSONO; INTAN KOMALASARI; SRI MULYATI
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v18i2.120

Abstract

Abstract Background: Coronary heart disease (CHD) is a disease that occurs due to coronary artery stenosis. This disease occurs due to accumulation of plaque in the coronary arteries, causing the artery lumen to stenosis. Stenosis of 70% or more will cause a disruption in myocardial oxygen supply and demand. The degree of stenosis can be assessed by the angiographic scoring system, namely the gensini score. Inflammation plays an important role in atherosclerosis. High Sensitivity C-Reactive Protein is a marker of inflammation that can play a risk factor as well as a predictor of coronary heart disease and can play a direct role in the atherosclerosis process. Objective: To determine the relationship between hs-CRP and the severity of angiographic lesions measured by gensini scoring in patients with stable angina at RSAL DR Ramelan Surabaya. Methods: Descriptive analytic study research. The research design uses cross sectional method and the sampling method used is purposive sampling. Samples were taken as many as 16 medical records and blood samples of CHD patients who underwent angiography and were measured using Gensini scores in Dr. Rumkital. Ramelan Surabaya. The research data is then processed descriptively. Results: A significance value of 0.001 <α (0.05) was obtained, and a correlation value of 0.726 showed an association between levels of hs-CRP and degree of angiography lesions based on gensini scores in patients with stable coronary heart disease in Dr. Rumkital Dr. Ramelan Surabaya. Conclusion: there is a significant relationship between increased levels of hs-CRP with the severity of angiographic lesions measured by gensini scores
Pengaruh Pencemaran Logam Berat Timbal (Pb) dan Ekskresi Iodium Urine (EIU) Terhadap Kejadian Stunting Pada Anak di Surabaya LEONI; WIENTA DIARSVITRI; VERNA BIUTIFASARI
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract

ABSTRACT Background : The existence of children, living in the coastal area with such risk of suffering from lead (Pb) intoxication, is still considered high. This pollutant plays a role in children’s growth and development. Lead (Pb), existing in our body, would directly reduce the amount of iodine that is absorbed by our body and in the end, would reduce the number of hormones affecting both physical growth and mental development for instance Growth Hormone, Thyroid Hormone, and Insulin-like Growth Factor (IGF-1). Other than Lead (Pb), growth is affected by another factor such as heredity, nutrition, and physical activity. This study serves the purpose of determining the effect of lead (Pb) pollution and Urinary Iodine Concentration (UIC) on the occurrence of stunting in children at the age of 25-60 months old at the urban village of Kedung Cowek Surabaya. Methods : observational analytic study a cross-sectional study design, by using a quantitative method which was used on 27 mothers whose children are 25-60 months old at Posyandu RW 2 and RW 3 urban village of Kedung Cowek Surabaya. The sample was chosen using a purposive sampling method. Data was collected through weight and height measurement, age, KMS (Card Towards Health), KIA (Kartu Ibu dan Anak), and questionnaires done by interviewing. Bivariate analysis was performed using Kruskal-Wallis. Results : Based on the laboratory test, it is shown that there’s no lead (Pb) pollution detected in seawater with the final result of 0,00035 mg/L (polluted > 0,008 mg/L). Based on Kruskal-Wallis, Urinary Iodine Concentration (UIC) doesn’t influence the occurrence of stunting based on deviation standard and nutritional status from the Ministry of Health (p = 0,409). Conclusion : There is no effect of lead (Pb) pollution and Urinary Iodine Concentration (UIC) on the occurrence of stunting in children at the age of 25-60 months old at the urban village of Kedung Cowek Surabaya.
Ekstrak Kulit Pisang Kepok (Musa paradisiaca) Menurunkan Kadar AST pada Tikus Putih yang Diinduksi Diet Tinggi Lemak STEFANUS DJONI HUSODO; ASAMI RIETTA KUMALA; INDRI NGESTI RAHAYU
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v18i2.122

Abstract

ABSTRACT Background. Non-alcoholic fatty liver disease (NAFLD) is closely related to the incidence of obesity and dyslipidemia. Increased levels of Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) are the most frequently performed liver function tests that can be used as a benchmark for suspicion of NAFLD. Banana peels contain flavonoids and phenolics which are antioxidants that can function as hepatoprotectors. Aim. Proving the effect of Kepok banana peel extract on AST and ALT of Wistar rats induced high fat diet. Method. experimental study with a post-test only control group design, with four treatment groups. There is negative control group only given four weeks standard diet (K-), positive control group only given four weeks high-fat diet (K+), and two treatment group where the rats were given two weeks high-fat diet then were given two weeks high-fat diet plus Kepok banana peel extract at a dose of 200 mg/kg BW (K1) and 400 mg/kg BW (K2). Result. the highest mean AST levels were in the negative control group and the lowest was the K2 group. Meanwhile, the highest mean of ALT was in the positive control group and the lowest was the K2 group. Based on the Kruskal Wallis test, the significance of the AST variable was not different (p>0,05), but the ALT variable was significantly different (p<0,05). Significant differences from the Mann Whitney-U test (p<0,05) were obtained between the negative control group and the positive control, the negative control group with K2 and the positive control group with the K2 group). Conclusion. The administration of Kepok banana peel extract (Musa paradisiaca formatypica) showed a significant decrease in ALT levels in Wistar strain white rats induced by a high-fat diet, but it was not significant for AST levels

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