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Medical and Health Journal
Published by Universitas Jenderal Soedirman
ISSN : -     EISSN : 28073541     DOI : https://doi.org/10.20884/1.mhj.2023.2.2.8053
Core Subject : Health,
Medicine & Pharmacology
Medical and Health Journal (EISSN. 2807-3541) is containing various articles/ manuscripts in the forms of research article, systematic reviews, case reports in the field of medicine focusing on basic medicine, clinical medicine, biomedical sciences, medical biotechnology, and public health. This journal is published by Universitas Jenderal Soedirman, Purwokerto, Indonesia.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 124 Documents
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HIPERTENSI PADA ANAK: TINJAUAN PUSTAKA Pratama, Radya Putra; Alexandra, Florence; Saad, Nursan
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.11952

Abstract

Hypertension in the pediatric population is a serious health problem that needs attention. Although the incidence is not as high as in adults, pediatric hypertension can increase the risk of cardiovascular and kidney disease later in life. This article aims to review the definition, epidemiology, etiology, pathogenesis, clinical manifestations, diagnosis, and management of pediatric hypertension. The causes of hypertension in the pediatric population can be divided into primary hypertension, which is generally associated with obesity and metabolic syndrome, and secondary hypertension, which is most often caused by kidney disorders. The diagnosis of pediatric hypertension is established through history taking, physical examination, and investigations. Management of pediatric hypertension includes lifestyle modifications and administration of antihypertensive drugs, depending on the severity and presence of target organ damage. Regular blood pressure checks after the age of 3 years are important so that pediatric hypertension can be detected and treated early to prevent long-term complications.
CASE REPORT : BENDA ASING DI TELINGA BAGIAN TENGAH PADA PASIEN DENGAN OTITIS MEDIA SUPURATIF KRONIK Kusdaryanto, Wahyu Dwi; Nafiisah, Nafiisah; Firinda, Rizma Haidif; Sinensis, Rizki Amelia
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12066

Abstract

Latar Belakang : Benda asing di telinga tengah merupakan kasus yang jarang, biasanya dapat terjadi karena adanya perforasi membran timpani terlebih dahulu sehingga benda asing masuk ke telinga tengah. Tujuan: Melaporkan suatu kasus benda asing telinga tengah yang jarang ditemukan. Laporan Kasus: wanita berusia 53 dengan diagnosis corpus alienum di cavum timpani dengan otitis media supuratif kronik telinga kanan.dan telahndilakukan evakuasi benda asing secara lokal anestesi dengan endoskopi telinga Pertanyaan Klinis: Apakah teknik yang tepat dalam pengambilan benda asing di telinga tengah. Telaah Literatur: Berbasis bukti mengenai teknik evakuasi pengambilan benda asing di telinga tengah melalui literatur. Hasil: Evakuasi benda asimg di telinga tengan dapat dilakukan melalui trasnkanal dengan endoskopi telinga. Kesimpulan: Evakuasi benda asing di telinga tengah harus dilakukan secara hati-hati dengan memperhatikan jenis benda asing, kepatuhan pasien, tehnik dan isntrumen yang tepat.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN MINUM OBAT ANTIHIPERTENSI PADA PASIEN PROLANIS LANSIA DI WILAYAH KERJA PUSKESMAS TAMBAK KABUPATEN BANYUMAS Amalia, Ary Nahdiyani; Fitriyani, Novita Endang; Arfani, Anun
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12172

Abstract

Family is a factor that has a big impact on compliance because it will motivate sufferers to be more confident when dealing with the health problems they are experiencing. This study aims to determine the relationship between support provided by the family and compliance with hypertension treatment in elderly prolanis patients at Tambak 1 and 2 Community Health Centers. The study design used was cross-sectional analytical observation. The research began in April-May 2023 at Tambak 1 and 2 Community Health Centers and was conducted on 92 patients. Data were collected using a questionnaire and Spearman's Rho testing was carried out. The results of the study showed a value of p = 0.002 (p < 0.05), which means that there is a significant relationship between family support and compliance with taking medication for elderly prolanis patients at Tambak 1 and 2 Community Health Centers. The correlation coefficient (r) was obtained at 0.321 and the direction of the relationship obtained a positive r value, meaning that the more the family supports the sufferer, the higher the degree of compliance with treatment. The conclusion that can be drawn is that compliance with hypertension treatment is closely related to the support provided by family members of elderly prolanis patients at Tambak 1 and 2 Community Health Centers. The Community Health Center can provide information, education or health counseling to hypertension prolanis participants about the importance of hypertension treatment compliance and the role of the family. in providing support to maintain stable blood pressure in prolanis patients.
EKSTRAK TUMBUHAN SEBAGAI AGEN ANTIMIKROBA UNTUK METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA): REVIEW Pauzi, Rizqi Yanuar; Septiya, Lia; Ihtiaringtyas, Suci; Wahyudin, Wahyudin
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12282

Abstract

Plant extracts have become an intriguing subject of research in the search for effectiveantimicrobial agents against Methicillin-Resistant Staphylococcus Aureus (MRSA), which is a global health issue due to its resistance to various antibiotics. Several studies have shown that compounds such as alkaloids and polyphenols in plants are responsible for their antimicrobial properties. Extracts from plants such as Azadirachta indica, Psidium guajava, and Rhamnus californica have demonstrated antibacterial activity against MRSA. Other research indicates that compounds like Psorothatin C from Psorothamnus fremontii are also effective against MRSA. The main challenge in managing MRSA infections is resistance to conventional antibiotics like vancomycin. Therefore, further research on plant extracts and synthetic compounds with antimicrobial activity against MRSA could provide significant contributions to the development of new therapies. Approaches involving the combination of plant extracts with conventional antibiotics also show potential in enhancing treatment effectiveness. A deep understanding of the mechanisms of action of these plant extracts is crucial for developing effective treatment strategies, and with further research, plant extracts could become an important alternative in addressing MRSA infections that are resistant to antibiotics.
HUBUNGAN STATUS VAKSINASI DENGAN KEJADIAN REINFEKSI COVID-19 PADA CIVITAS AKADEMIKA UNIVERSITAS JENDERAL SOEDIRMAN Nara, Shaynika Rui; Rahmawati, Indah; Fatchurohmah, Wiwiek
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12552

Abstract

Backgrounds: Covid-19 reinfection occurs when someone who has experienced Covid-19 and is declared cured but is re-infected with a positive result on the PCR test with a period between the first and second infection > 90 days. This event is related to the body's immune response which is influenced by vaccine administration. Therefore, further studies need to be conducted to see the relevance between vaccination status and the incidence of Covid-19 reinfection. Objective: Knowing the relationship between vaccine status and the incidence of Covid-19 reinfection in the academic community of Jenderal Soedirman University. Method: An Analytical observational research with cross-sectional approach. The number of respondents in this study was 154 respondents. This study used a questionnaire in the form of google form as a data collection tool. Data were processed using a correlation test, the Chi-Square test to see the relationship between variables. Results: The results of this study showed that the incidence of reinfection found was 14.9%. The vaccination status of respondents at the time of Covid-19 reinfection who had not been vaccinated was 8.6%, half dose vaccine was 17.4% and full dose vaccine was 74%. The results of the Chi-square test between vaccination status and the incidence of reinfection indicate that there is no significant relationship (p-value > 0,05). Conclusion: There is no relationship between vaccine status and the incidence of Covid-19 reinfection in the academic community of Jenderal Soedirman University.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KUALITAS HIDUP PADA PASIEN TUBERKULOSIS RESISTAN OBAT Virgin, Aprilia; Rahmawati, Indah; Yuliani, Massita Dwi
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12577

Abstract

With treatment for Drug Resistant Tuberculosis requiring the consumption of drugs for a long duration, the importance of good support becomes a necessity. Support from family is a very important aspect for individuals who experience Drug Resistant Tuberculosis as the main source of support. Family support is very important in improving the quality of life of patients with drug-resistant tuberculosis. This study identified the relationship between family support and quality of life in patients with drug-resistant tuberculosis. This study is an analytic observational with a cross-sectional design in the target population of patients with RR (Rifampicin Resistant) and MDR (Multi Drug Resistant) TB who are undergoing treatment at Prof. Dr. Margono Soekarjo Hospital and Ajibarang Hospital in 2022-2023. A total of 32 people were selected as respondents using consecutive sampling method. Inclusion criteria were RR and MDR TB patients who sought treatment at Prof. Dr. Margono Soekarjo Hospital and Ajibarang Hospital in 2022-2023 and were willing to become research respondents after signing informed consent. Exclusion criteria included unclear domicile address, patients not in place during data collection, not filling out the questionnaire completely, not cooperating in the implementation of the study and patients with comorbidities such as HIV, DM, hypertension and COPD. Data analysis used Non Parametric test with Spearman method. A total of 65.6% of subjects had high family support, 31.3% had moderate family support and 3.1% of subjects had low family support. A total of 78.1% of subjects had a good quality of life while 21.9% of subjects had a poor quality of life. The results of the data analysis test using Spearman obtained a significance value of p=0.005 with r=0.481 which showed a significant relationship between family support and quality of life in Drug Resistant Tuberculosis patients with a positive correlation direction and moderate correlation strength. It is concluded that family support is related to quality of life in patients with drug-resistant tuberculosis. Keywords: Family support, quality of life, Drug Resistant Tuberculosis
PERBANDINGAN KLORAMFENIKOL, ERITROMISIN DAN FORMALIN DENGAN BERBAGAI DOSIS TERHADAP PENGHAMBATAN PERTUMBUHAN Clostridium perfringens Peramiarti, IDSAP; Syamsu Hidayat, Muhammad Zaenuri
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12735

Abstract

Death is the cessation of function of the circulatory system and respiratory system, or brain stem death has occurred. Decomposition is natural process that occur shortly after death. The main bacteria involved in the decomposition process is Clostridium perfringens. The process of decomposition sometimes need to be inhibited by the preservation bodies. Preserving the corpse is a medical procedure for the provision of certain chemicals such as formalin or can used a broad spectrum antibiotic chloramphenicol and erytromicine. This study aims to test the effectiveness of various doses of chloramphenicol, erytromicine and formaline in inhibiting the growth of Clostridium perfringens. This was an experimental study with post test only and contol group design. The treatment of various doses of chloramphenicol 0,25 µg/ml, 0,5 µg/ml, 1 µg/ml, 2 µg/ml, and 4 µg/ml; Erythromycin doses were 0,2 µg/mL, 0,4 µg/mL, 0,8 µg/mL, 1,6 µg/mL, and 3,2 µg/mL and formalin was given at 2%, 4%, 6%, 8%, and 10% in liquid medium Nutrient Broth. Incubated for 24 hours at 37 ° C, and then planted in agar plate wiith spread plate method to determine the growth of bacteria. Bacterial growth was calculated by colony counter, then the percentage inhibition was determined. Data were analyzed using parametric tests One Way Annova and Post Hoc Test. The effective concentration was determined by Minimum Inhibitory Concentration 50 (MIC50). Data were analyzed using One Way Annova test, showed p value=0,009 (p<0,05) which meant that there were significant difference between the number of colony inhibition with number of doses given to C. perfringens, and the results of Post Hoc Test concentration of formaldehyde 10% and 8% had the lowest number of colonies or has the ability to inhibit the growth of c. perfringens bacteria most of 80% and 63%, so it can be said to be effective concentration (MIC50) at 8% formalin treatment with inhibition of growth of 63%.
ANGIOSARCOMA PILORUS: LAPORAN KASUS Ammar, Faiq Muhammad; Khalik, Arief Ismail
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12758

Abstract

Angiosarcoma is a type of soft tissue cancer originating from blood vessel endothelial cells that is rare and very aggressive. Angiosarcoma has a poor prognosis with low survival rates. There is no standard management that can be used as a guide for treatment, making it a challenge for the treating team. This case report aims to examine further the clinical manifestations, diagnosis and treatment of pyloric angiosarcoma. We report a case of a 55 year old woman with complaints of black stools, accompanied by hard and difficult bowel movements, upper left abdominal pain and heartburn that felt all the way to the back, a bloated stomach, weight loss, and appetite. Esophagogastroduodenoscopy examination showed a mass in the gastric antrum. Abdominal CT scan with contrast shows a mass with centripetal filling enhancement that is attached and difficult to separate from the pyloric structures of the stomach. Laparotomy, excision of the tumor mass and pyloric resection, duodenal gastric anastomosis were performed in this patient. Anatomical pathology examination gave results of angiosarcoma.
STUDI LITERATUR: POTENSI BUAH PARIJOTO (Medinilla speciosa) SEBAGAI ANTIMALARIA Ihtiaringtyas, Suci; Pauzi, Rizqi Yanuar; Setyanto, Muhamad Rifqy
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12805

Abstract

Malaria is one of the deadliest infectious diseases in the world. It is caused by the parasite Plasmodium spp. and transmitted through the bites of female Anopheles mosquitoes. This disease remains a significant global health problem, particularly in tropical and subtropical regions. Approximately 41% of the world's population is at risk of malaria infection. Artemisinin-based Combination Therapy (ACT) remains the gold standard for malaria treatment, but resistance is beginning to develop, necessitating alternative treatments from natural sources found in plants. Parijoto (M. speciosa) is an exotic fruit native to Indonesia that grows abundantly in mountainous areas. The fruit has been widely used by local communities to treat various ailments, including mouth ulcers, inflammation, and diarrhea. Numerous studies have been conducted to prove the effectiveness of this plant's fruit as an alternative natural remedy. This study aims to investigate the potential of parijoto fruit (M. speciosa) as an antimalarial agent. The method used is a literature review with a Systematic Literature Review design. Articles were sourced from the Google Scholar database, including both national and international journal articles. Based on the research findings, parijoto fruit has been proven to contain bioactive compounds, including phenolics, flavonoids, saponins, tannins, alkaloids, cardenolides, and glycosides. These secondary metabolite compounds in the plant have been shown to possess antioxidant, antidiabetic, antimicrobial, anticancer, and other beneficial activities. It is hoped that the secondary metabolite compounds contained in parijoto fruit (M. speciosa) have the potential to serve as antimalarial agents.
HUBUNGAN STATUS GIZI DENGAN KADAR HEMOGLOBIN PADA SISWI SMP DI WILAYAH KERJA PUSKESMAS PURWOKERTO TIMUR: STUDI CROSS SECTIONAL Hapsari, Ariadne Tiara; Nurusifa, Miska Qorinareta; Wicaksono, Madya Ardi
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12882

Abstract

Background: Anemia is a condition where the number of red blood cells or hemoglobin is less than normal. Lack of hemoglobin can be affected by nutritional status. Poor nutritional status can lead to reduced hemoglobin levels resulting in anemia. Objective: To identify the relationship between nutritional status and hemoglobin (Hb) levels in junior high school adolescent girls at Purwokerto Timur 2 Health Center. Methodology: Observational analytic research with a cross sectional approach. The sample in this study was 278 seventh grade junior high school students who were taken by total sampling method. Data taken in the form of hemoglobin levels and nutritional status values determined by Body Mass Index, both data recorded in medical records. Results: There is a median result of 18.13 for nutritional status with a minimum value of 10.84 and a maximum value of 41.20. While the median results for hemoglobin levels were 11.20 with a minimum value of 4.70 and a maximum value of 18.10. The number of Body Mass Index underweight majority had a value (53.2%), while for anemia the majority were in moderate anemia (36.7%). Conclusion: There is no relationship between nutritional status and hemoglobin levels in junior high school students in the working area of Puskesmas Purwokerto Timur. Latar Belakang: Anemia merupakan kondisi jumlah sel darah merah atau hemoglobin kurang dari normal. Kurangnya kadar hemoglobin dapat dipengaruhi oleh status gizi. Status gizi yang buruk dapat menyebabkan berkurangnya kadar hemoglobin hingga terjadi anemia. Tujuan: Mengidentifikasikan hubungan status gizi dengan kadar hemoglobin (Hb) pada Siswi Putri SMP di Puskesmas Purwokerto Timur 2. Metodologi: Penelitian analitik observasional dengan pendekatan cross sectional. Sampel pada penelitian ini sebanyak 278 siswi kelas VII SMP yang diambil dengan metode total sampling. Data yang diambil berupa nilai kadar hemoglobin dan nilai status gizi yang ditentukan oleh Indeks Massa Tubuh, kedua data tersebut tercatat dalam rekam medis. Hasil: Terdapat hasil median 18.13 untuk status gizi dengan nilai minimum 10.84 dan nilai maximum 41.20. Sedangkan hasil median untuk kadar hemoglobin 11.20 dengan nilai minimum 4.70 dan nilai maximum 18.10. Jumlah Indeks Massa Tubuh underweight mayoritas memiliki nilai (53.2%), sedangkan untuk anemia mayoritas masuk dalam anemia sedang (36.7%). Kesimpulan: Tidak ada hubungan antara status gizi dengan kadar hemoglobin pada siswi SMP di wilayah kerja Puskesmas Purwokerto Timur 2.

Page 7 of 13 | Total Record : 124

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