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Journal of Multidisciplinary Science: MIKAILALSYS
Published by Lembaga Yasin Alsys
ISSN : 29873924     EISSN : 29872286     DOI : https://doi.org/10.58578/mikailalsys
Core Subject : Science, Education, Agriculture, Social, Engineering,
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Environmental Science Physics Social Sciences Other
Journal of Multidisciplinary Science : MIKAILALSYS [2987-3924 (Print) and 2987-2286 (Online)] is a double blind peer reviewed and open access journal to disseminating all information contributing to the understanding and development of Multidisciplinary Science. Its scope is international in that it welcomes articles from academics, researchers, graduate students and policy makers. The articles published may take the form of original research, theoretical analyses, and critical review. All articles should be in English or Arabic. MIKAILALSYS publishes 3 editions a year in April, August, and December (Unless there is co-publication with conference organizers). MIKAILALSYS journal has been indexed by Harvard University, Boston University, Dimensions, Scilit, Crossref, Web of Science Garuda, Google Scholar, and Base.
Arjuna Subject : Umum - Umum
Articles 157 Documents
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Isolation and Molecular Characterisation of Chlorogonium sp. from Industrial Wastewater Abershi, Ajiduku Leyoa; Ikwebe, Joseph; Stephen, Ezeonu Chukwuma; Mafe, Alice Njolke; Abah, Moses Adondua
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3851

Abstract

Microalgae are photosynthetic, unicellular microorganisms also known as phytoplankton. They are small plant-like entities. In this research, the sample were collected from cement factory in a sterilised 20L container wrapped with foil paper and were transported down to Federal University, Wukari where it was kept in refrigerator at biochemistry laboratory. Blue-Green media (BG-11) was prepared. Wastewater containing Microalgae obtained from cement wastewater pond were cultivated in BG-11 medium to determine the growth of the organism. BG-11 medium contained macronutrients, trace metals and some vitamins which aid the growth of the organism. The wastewater sample containing with suspected microalgae was inoculated (inoculum ratio = 25%) and incubated under atmospheric CO2 at room temperature (30±2°C) in our laboratory for two to three weeks during the incubation period. In order to purify the isolates, the upper growth layer was first decanted into a freshly produced medium and then plated on BG-11 media that had been solidified with 1% agar-agar. For several of the cultures, growth on the agar plates continued for around three weeks. Following repeated sub-culturing, the emerging greenish colonies were re-emerged into a sterile BG-11 agar medium. In isolation of organism from the industrial cement waste water, the isolate was identified by morphological and molecular identification by extracting the DNA, run the electrophoretic analysis and PCR using primers for 18S rRNA eukaryotic microalgal and then run the sequence analysis. The results of this study obtained, indicated that, the electrophoretic result show the band has 1800-2000base pair and the organism isolated from the industrial cement waste water were chlorogonium sp. with a percent similarity of 78.65% and accession number of OR886595 based on data Gene Bank blast results.
Health Risk Assessment of Heavy Metals in Water Sources from Selected Regions in Yola North, Adamawa State, Nigeria Stephen, Hyelda; Bassi, Wasinda Nuhu; Sirante, Richard Martin; Alli, Rejoice Monday
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3852

Abstract

Access to clean drinking water is essential for sustainable development and human health, but heavy metal contamination poses a significant threat. This study assessed health risks linked to heavy metals in drinking and household water sources in Yola North. Water samples from surface water (Benue River), groundwater (wells and boreholes), and tap water were analysed for physicochemical properties and heavy metal content. The average daily dosage (ADD), hazard quotient (HQ), and hazard index were estimated to assess the non-carcinogenic risk (HI) and carcinogenic risk (LCR) of heavy metals from the study water sources. The physicochemical properties of water samples showed pH values within WHO limits, with temperature ranging from 23°C to 32°C, turbidity within acceptable levels, electrical conductivity varying significantly, and total dissolved solids generally meeting WHO standards. The levels of cadmium (Cd) and lead (Pb) exceeded WHO guidelines in all water samples, with the highest concentrations found in tap water (90 μg/L Cd) and surface water (210 μg/L Pb). There were considerable non-carcinogenic hazards indicated by the HQ and HI values for Pb and Cd via ingestion exceeding the threshold of 1. The LCR estimates revealed carcinogenic risks from Cd exposure in all water sources and elevated cancer risk from arsenic in surface water and tap water. Across all sources, lead presented a tolerable cancer risk. The study emphasises how critical it is to implement mitigation plans and other measures to address heavy metal contamination in the area's water sources.
In-Silico Analysis of Agrocybe aegerita Bioactive Compounds Targeting HER-2 Positive Breast Cancer Protein Moses, Iyekekpolor Osamudiame
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3866

Abstract

This study explores the anti-cancer potential of bioactive compounds derived from Agrocybe aegerita, focusing on their interaction with the HER-2 protein, which is commonly overexpressed in aggressive breast cancers. Using in-silico molecular docking techniques via the SwissDock platform and AutoDock Vina algorithm, the binding affinities of three bioactive compounds—ceramide, ganoderic acid, and galectin—were evaluated and compared to standard cancer drugs, including doxorubicin, lapatinib, and pazopanib. The results demonstrated that ganoderic acid exhibited the highest binding affinity to HER-2 (-6.34 to -6.18), comparable to lapatinib and pazopanib, suggesting its strong therapeutic potential. Ceramide and galectin showed moderate affinities, indicating possible roles in complementary or synergistic therapies. The findings suggest that A. aegerita, particularly its ganoderic acid compound, holds promise as a natural source for novel anti-cancer agents, potentially offering comparable efficacy to synthetic drugs with fewer side effects. However, the limitations of in-silico studies are acknowledged, and further in vitro and in vivo validation is necessary to confirm these promising results. This research contributes to the growing body of knowledge on natural bioactive compounds, underscoring the potential of mushrooms in cancer therapy and advocating for more extensive studies to harness their medicinal properties.
Effect of Processing on Nutritional and Antinutritional Composition of SAMPEA-11 and 20-T Cowpea Cultivars Titus, Stephen Dio; Abershi, Ajiduku Leyoa; Francis, Achilus; Mafe, Alice Njolke; Samuel, Kennedy Banja; Daniel, Ejembi Ocholi; Ojogbene, Eleojo
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3867

Abstract

This study investigates the effects of boiling and roasting on the nutritional and antinutritional composition of SAMPEA-11 and SAMPEA 20T. Ash content increased after roasting, with SAMPEA-11 rising from 2.5% to 3.1% and SAMPEA 20T from 2.7% to 3.4%. Crude fiber content displayed varied trend; in SAMPEA 20T an increase from 5.0% to 6.2% post-roasting, while SAMPEA-11 remained relatively stable. Lipid content increased significantly in roasted SAMPEA 20T by 2.8% and boiled SAMPEA-11 by 1.5. Protein content in SAMPEA-11 decreased after boiling and roasting, dropping by 4.5% and 2.9%, respectively. SAMPEA 20T showed an increase of 1.2 after boiling. For the antinutrients, boiling significantly reduced tannin levels in SAMPEA-11 from 0.45 mg/g to 0.23 mg/g, while roasting further reduced it to 0.15 mg/g in SAMPEA 20T. Oxalate levels increased after boiling, from 0.18 mg/g to 0.31 mg/g in SAMPEA-11 and 0.20 mg/g to 0.29 mg/g in SAMPEA 20T, while phytates decreased by 30% across both varieties after roasting. In the same vein, boiling and roasting both reduced concentrations lectin. While folate content, also decreased significantly in SAMPEA-11 after roasting, from 270 to 140 µg/100g. In contrast, SAMPEA 20T retained more folate, with a minimal reduction after boiling (250 to 220 µg/100g). Hence, Roasting was found to enhance shelf life by reducing moisture content while improving carbohydrate and mineral content. However, boiling appears more effective in retaining essential nutrients like protein and folate, especially in SAMPEA 20T. These findings provide insights for optimizing processing techniques to improve nutritional quality of cowpeas.
The Rise of Biochemical Sensors: Technology for Real-Time Health Monitoring (Applications and Future Scope) Moses, Iyekekpolor Osamudiame
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3907

Abstract

Biochemical sensors integrated into wearable health technology represent one of the most transformative innovations of the 21st century. This review delves into the evolution, principles, and real-time applications of biochemical sensors and their role in personalized health monitoring. Wearable biochemical sensors, capable of continuously measuring various biomarkers like glucose, lactate, cortisol, and electrolytes, are revolutionizing healthcare by enabling proactive management of chronic diseases, including diabetes, cardiovascular disorders, and mental health issues. Advances in biosensing technologies, coupled with the use of AI and machine learning algorithms, have enhanced the sensitivity and accuracy of these devices, ensuring that critical health data is available in real-time. From glucose monitoring devices like Abbott's FreeStyle Libre to the latest nanomaterial-based sensors, these innovations are reshaping healthcare delivery by shifting the focus from hospital-centered treatments to patient-centric, continuous monitoring systems. This review provides an in-depth analysis of the technological advancements, challenges, and future directions in biochemical sensors, focusing on key technologies such as electrochemical, optical, and enzymatic sensors. It also highlights the critical role of AI in interpreting the complex data generated by these sensors, paving the way for more efficient diagnostics and predictive healthcare models. Furthermore, the paper explores how these sensors have been applied in infectious disease detection, particularly during the COVID-19 pandemic, and discusses their potential to enhance global health surveillance systems. In conclusion, wearable biochemical sensors represent a significant leap forward in the pursuit of personalized medicine, offering real-time diagnostics and timely interventions for disease management. The future of healthcare is closely tied to the ongoing innovations in sensor technology, with the promise of even more advanced and multifunctional devices on the horizon.
Circular Economy in Morocco: Status and Perspectives and Policy Implications for Vietnam Van, Truong Hoang Thuy
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3949

Abstract

This paper explores the current status of the circular economy (CE) in Morocco, its potential future directions, and policy implications for Vietnam. The concept of CE, which promotes sustainable resource use, waste reduction, and regeneration, is increasingly gaining global traction. Morocco, having made significant progress in sectors such as waste management, agriculture, renewable energy, and water resource management, serves as a valuable case study. Key initiatives like the National Solid Waste Management Program (PNDM) and the "Green Morocco Plan" highlight Morocco’s successful integration of CE principles. Despite challenges such as financial constraints and low public awareness, Morocco's transition to a circular economy presents numerous opportunities, including job creation and innovation. For Vietnam, which faces growing environmental and resource pressures, Morocco’s experience offers critical insights. By adopting CE principles in waste management, agriculture, renewable energy, and water management, Vietnam can move toward more sustainable development. The paper suggests specific policy recommendations, including fostering public-private partnerships, enhancing regulatory frameworks, and promoting green financing. The lessons drawn from Morocco’s journey can help Vietnam align its growth with environmental sustainability, positioning both countries as leaders in the global shift towards a circular economy.
Optimization of Distance Learning Systems Using Artificial Intelligence and the Internet of Things in Improving the Quality of Education in the Post-Pandemic Era Yahya, Saifudin; Islam, Khoirul; Nashihin, Durrotun
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3953

Abstract

The COVID-19 pandemic forced a sudden change from face-to-face learning to Distance Learning (PJJ), posing challenges in the quality of learning and student interaction. This study examines the application of Artificial Intelligence (AI) and the Internet of Things (IoT) to optimize the PJJ system in the post-pandemic era. The goal is to evaluate the impact of AI in personalizing learning and IoT in improving student interactivity and collaboration, as well as identify the challenges of implementing this technology. The research uses a mixed-methods approach by combining qualitative and quantitative analysis. Data were obtained from 50 educators, 100 students, and 20 administrators through questionnaires, in-depth interviews, and participatory observations. Correlation tests and logistic regression are used to assess the influence of AI and IoT on learning quality. The results show that 85% of students and 78% of educators agree that AI helps in customizing learning materials. IoT also increases student engagement, with 76% of students feeling more engaged and the likelihood of student engagement increasing 2.35 times greater with IoT. Key challenges include limited technological infrastructure and lack of training for educators. In conclusion, AI and IoT have great potential in improving the quality of education, but support is needed for infrastructure and educator training so that the implementation of these technologies is optimal.
Mu ̈ntz’s Theorem in 2-Inner Product Spaces and It’s Applications in Economics Kumar, Nand Kishor; Sahani, Suresh Kumar
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3991

Abstract

This study establishes a 2-inner product space, as well as its basic attributes and proof. The proof of Müntz’s theorem in 2-inner product spaces was demonstrated. Müntz’s Theorem finds a natural extension and application in the realm of 2-inner product spaces. By understanding the conditions under which certain functions form dense subsets, we can gain insights into the approximation properties and structural characteristics of these spaces. Further research may explore specific examples and ramifications of Müntz’s theorem in diverse areas of mathematics and their applications. Müntz’s Theorem provides valuable insights in economics by addressing the question of how well economic functions can be approximated when the available data or model inputs are restricted.
Evaluation of Heavy Metal Contamination in Amaranthus hybridus (Spinach) Titus, Stephen D.; Apollos, Markus R.; John, Senufa; Usman, Patricia G.; Garba, Liatu C
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.3995

Abstract

Heavy metals contamination in edible plants poses significant risks to human health and environmental sustainability. This study evaluates heavy metal contamination in Amaranthus hybridus L. (spinach) collected from three sites: Nyabunkaka River, Kogin Sarki, and Mayo-Gwoi River in Jalingo, Taraba State, Nigeria. The study aimed to determine the levels of lead (Pb), cadmium (Cd), chromium (Cr), zinc (Zn), copper (Cu), nickel (Ni), manganese (Mn), and cobalt (Co) in spinach samples using Atomic Absorption Spectrophotometry (AAS). Results revealed that Pb concentration in spinach from Nyabunkaka slightly exceeded the FAO permissible limit, while Cd, Cr, Zn, Cu, Ni, Mn, and Co levels in all samples were below FAO reference values, indicating minimal contamination risks. These findings highlight the potential environmental pollution near Nyabunkaka River and suggest that spinach from the selected areas remains largely safe for human consumption, except for slight Pb contamination. The study emphasizes the need for continuous monitoring to ensure food safety.
Comparative Study on the Proximate Composition and Amino Acid Levels in Chanterelle (Cantharellus cibarius) and Wood Ear (Auricularia auricula) Mushroom Samples Adebisi, Arowora Kayode; Abah, Moses Adondua; Ugwuoke, Kenneth Chinekwu; Dooshima, Arowora Mercy; Ndoma, Odi Raphael; Okani, Precious Chizaram; Ominisan, Kimi Smith; Gbadebo, Adetoyi Moses; Olamilekan, Aliyu Najeeb; Kwame, Asare Bernard
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 3 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i3.4052

Abstract

Mushrooms have been consumed by mankind for millennia. They are macrofungi with a distinctive fruiting body which can be hypogeous or epigeous, large enough to be seen with unaided eyes. They are not widely consumed due to lack of information on its nutritive value. Therefore, this research was carried out to compare the proximate gross energy composition as well as amino acids levels in two selected edible mushrooms (Cantharellus cibarius and Auricularia auricula). Fully matured species of Chanterelle mushroom (Cantherellus cibarius) and Wood ear mushroom (Auricularia auricula) were collected from different parts of Southern and Northern Cross River; Ikom and Bekwara precisely. The collected samples were air dried for 5 days and then stored in transparent polythene bag for analysis. The dried and stored mushroom were pounded to powdered form and then subjected to amino acid analysis using isocratic HPLC and proximate analysis for proximate composition using the standard methods of Association of Official Analytical Chemist (AOAC). The results of this research showed that chanterelle mushroom has high concentration of amino acids compared to Wood ear mushroom. However, there was significant differences (p<0.05) in the levels of isoleucine in both mushrooms. There were no significant differences in the proximate composition and gross energy levels of both mushroom species. Some of the amino acids detected in both mushrooms were: methionine, threonine, isoleucine, leucine, phenylalanine, valine, tryptophan, histidine, arginine, aspartic acid, glycine, alanine and glutamic acid. Based on the findings of this study, the two edible mushrooms were observed to have appreciable levels of gross energy and amino acids. However, Chanterelle mushroom had higher protein composition than wood ear. Hence, it can be concluded that Chanterelle mushroom has greater nutritive value and more suitable for consumption.

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