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Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan Ibnu Sina Ajibarang
ISSN : 29872987     EISSN : 29874793     DOI : 10.59841
Core Subject : Health,
Dentistry Health Professions Nursing Public Health Veterinary
Farmasi Klinis; Farmasi Sosial;Farmasi Klinikal;Farmasi Industri;Farmasi Kesehatan Masyarakat;Farmasi Klinik;Farmasi Komunitas;Farmasi Klinikal dan Sosial;Ilmu Biomedis;Epidemiologi;Kesehatan Masyarakat;Kedokteran;Gizi;Psikologi Kesehatan;K3;Manajemen Farmasi;
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 320 Documents
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Analisis Komparatif Efektivitas Antipiretik antara Bahan Alami dan Sintetik terhadap Penurunan Suhu Tubuh pada Mencit (Mus musculus) Umniyyah Azizah Al jufri; Surawalia Said; Siti Srihandayani Najib; Aqilah Nurul Izzah; Nurul Indah Lestari; Intan Rusdin; A. Nurfadiyah Izzaty Dwiputri
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3101

Abstract

Fever is a physiological response to infection or inflammation, characterized by an increase in body temperature beyond the normal threshold. To reduce fever, antipyretic drugs such as acetaminophen (paracetamol) and nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used. This study aimed to evaluate the antipyretic effectiveness of several drugs by observing their ability to reduce fever in mice induced with pyrexia using peptone solution. The method involved intraperitoneal administration of peptone to induce fever, followed by treatment with different classes of antipyretic agents. Body temperature was measured at regular intervals to assess the degree and duration of temperature reduction. The results are expected to show a comparative profile of each drug’s antipyretic activity and determine which agent is most effective in lowering body temperature. This experiment provides a scientific understanding of the pharmacodynamics of antipyretic drugs and supports evidence-based selection for fever management. The findings also contribute to laboratory-based pharmacological education and reinforce the clinical relevance of antipyretic classification.
Prosedur Penarikan Produk dan Pengelolaan Produk Kembalian dalam Rantai Distribusi Farmasi Niken Widya Ningrum; Nur Latipah Sulistiawanti; Nor Latifah
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3107

Abstract

Product recall and returned product management are essential in ensuring the quality, safety, and efficacy of pharmaceutical preparations in circulation. Data were obtained from various journals and official reports from 2018 to 2024 relevant to pharmaceutical recalls. With effective recall mechanisms, customer safety and quality of pharmaceutical services are anticipated to enhance continuously. This review highlights the significance of strengthening effective recall systems, human resource training, and the use of digital technology in distribution processes. This article aims to thoroughly examine the procedures for product recall and returned product management within the pharmaceutical distribution chain through a literature study. The review shows that despite the availability of national and international regulations, implementation still faces difficulties such as absence of unified information systems, insufficient collaboration among industry players and authorities, and less than optimal quality culture in the field. Additionally, difficulties in product tracking, documentation, and recall decision-making are also concerns.
Gambaran Stres Kerja pada Perawat di Rumah Sakit Tahun 2025 Resti Nilam Resmini; Munaya Fauziah
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3110

Abstract

Job stress is a problem that always exists and occurs in the world. Job stress is a psychosocial hazard that comes from various sources such as relationships with coworkers, work conditions, and work organizations, especially for nurses who work in hospitals. Because of the high intensity of always meeting and interacting directly with patients and families which is quite difficult and complex, it can be indicated as a trigger for job stress in nurses. This study aims to determine the picture of job stress in nurses in 2025. Using a literature review (Literature study) from the Garuda journal portal using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) with a qualitative approach with sampling using exclusion and inclusion criteria. The level of nurse stress tends to be in the moderate category (60.3%) or mild (55%) in (Khoirunnisa et al.) (Public Health et al., n.d.), (63.3%) in (Izzah Bialfi Hasanah et al). However, research also shows that a percentage of nurses experience severe stress (5%) in Khoirunnisa et al., (10%) in Izzah Bialfi Hasanah et al., and (61.4%) in Anwar et al. This relationship is closely linked to workload, with nurses with heavy workloads tending to experience moderate to severe stress. Similarly, inappropriate or disruptive work shifts are significantly associated with increased stress. Women tend to experience work stress more easily than men due to their dual roles (as nurses and housewives) and their tendency to use emotions when dealing with tasks. Although female nurses are often dominant (56.7% in the emergency department during the pandemic, 45% in outpatient settings), there is significant identification of work stress levels with age, gender, workload, and work shift characteristics. Hospitals are advised to develop psychosocial support programs for nurses, such as open sharing sessions, alternating refreshing activities, or providing counseling. These programs are crucial to helping nurses manage stress.
Uji Stabilitas Fisik dan Kimia Tablet Paracetamol dengan Berbagai Variasi Bahan Pengikat Muhammad Reihan Ridha; Muhammad Romansyah Khatami; Nor Latifah
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3111

Abstract

Tablets represent one of the most widely utilized solid pharmaceutical dosage forms, in which both physical and chemical stability parameters play a critical role in ensuring product quality and therapeutic efficacy throughout the shelf life. The stability of tablet formulations is influenced by various factors, including the type and concentration of binders used during manufacturing. This review aims to evaluate the effects of natural binders—specifically durian seed starch, cempedak seed starch, and mucilage from Dioscorea esculenta (lesser yam) tuber starch—on the quality of paracetamol tablets based on findings from the scientific literature. A systematic literature search was conducted using various academic databases. The reviewed studies revealed that all tested natural binders generally met the physical quality parameters outlined in the Indonesian Pharmacopoeia. However, increasing binder concentrations was associated with prolonged disintegration times and reduced solubility of the active pharmaceutical ingredient (API). These findings highlight the importance of selecting appropriate binder types and optimizing their concentrations to ensure effective drug release and maintain formulation stability during storage.
Uji Stabilitas Fisik Sediaan Sirup dari Berbagai Bahan Aktif Rifka Annisa; Khusnul Khotimah; Nor Latifah
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3115

Abstract

This review article discusses the evaluation of physical stability in syrup dosage forms, focusing on three studies that utilized different active ingredients: lime leaf extract, watermelon rind extract, and loratadine. The objective is to assess and compare the outcomes of physical tests such as pH, viscosity, organoleptic properties, and homogeneity under short-term storage conditions. Each study employed an experimental approach by formulating syrup and conducting physical evaluations over a specific period. The results demonstrated that all syrup preparations maintained acceptable physical stability throughout the observation period, with minor variations depending on the formulation and active substance. These findings emphasize the importance of consistent physical stability testing in pharmaceutical product development, especially for liquid dosage forms derived from natural ingredients or commercial drugs. Such testing is crucial to ensure product safety, efficacy, and consumer acceptability during storage and use.
Pendidikan Kesehatan Tentang Nutrisi Ibu Hamil di Puskesmas Krueng Barona Jaya Cut Oktaviyana; Syarifah Masthura
An-Najat Vol. 2 No. 1 (2024): FEBRUARI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i1.3118

Abstract

Nutrition is important for both the mother and the fetus during pregnancy. A healthy pregnancy requires a good diet to prevent problems for the mother and fetus during the first 1,000 days of the baby's life. One way to improve the health of pregnant women is to provide them with health education related to nutrition. The goal is to improve understanding of nutrition for a healthy pregnancy and optimal fetal growth and development. The method used was lectures and discussions with three pregnant women who participated in the activity. The result of this activity was an increase in knowledge, as evidenced by the fact that 90% of the questions on the post-test were answered correctly, compared to 60-70% on the pre-test. Therefore, it can be concluded that the participants' knowledge increased during the health education activity.
Implementasi Sistem ISO 14001 dalam Pengelolaan Limbah Industri Farmasi di Indonesia Hairunnisa Hairunnisa; Salma Fitriyanti; Nor Latifah
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3119

Abstract

This review explores the implementation of ISO 14001 in pharmaceutical waste management within Indonesia’s industry context. ISO 14001, as an Environmental Management System (EMS), offers a structured approach to reducing environmental risks and improving operational efficiency. The review analyzes five peer-reviewed articles published between 2023 and 2025, focusing on hospitals and pharmaceutical-related sectors. Findings reveal that ISO 14001 adoption contributes significantly to better waste segregation, reduced environmental impact, and enhanced organizational sustainability when implemented comprehensively. However, challenges such as lack of cross-unit coordination, limited policy support, and inadequate staff training hinder full system integration. The review also identifies the synergy of ISO 14001 with other standards such as ISO 45001 and ISO 22000 as a strategic advantage for industry-wide performance. Implications suggest the need for stronger regulatory frameworks and internal organizational commitment to transform ISO 14001 from a compliance tool into a driver of sustainable innovation.
Perilaku Masturbasi di Kalangan Remaja dan Kaitannya dengan Self-Concept Dodikrisno E Manery; Abdul M Ukratalo; Edwin Buranga; Arief Rahman S Kaliky
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3124

Abstract

Masturbation is a common aspect of sexual development in adolescents and plays a role in identity exploration and the formation of self-concept. Adolescence represents a critical developmental phase during which individuals seek to understand their identity, including their body and sexuality. Within a psychosocial context, masturbation may contribute positively to self-concept development when supported by a healthy understanding and an inclusive environment. However, social pressures, religious norms, and cultural values that prohibit or stigmatize masturbation often generate internal conflict, influencing adolescents’ self-perception. The resulting negative self-concept may lead to feelings of shame, guilt, stress, and adverse impacts on mental health. This study aims to examine masturbation behavior among adolescents and its association with negative self-concept. The method employed is a literature review, utilizing both scholarly books and peer-reviewed journal articles. Data collection techniques included gathering literature sources, reading and sorting data, note-taking, identifying relevant findings, and validating the information to support analytical interpretation. Findings indicate that adolescents with a positive self-concept are more capable of accepting their sexual behavior, including masturbation, without excessive guilt or shame. Conversely, those with a negative self-concept are more likely to experience internal conflict that compromises psychological well-being. Factors such as family support, open sexual education, and media influence play a significant role in shaping the relationship between masturbation and self-concept. Comprehensive sexual education can enhance adolescents’ understanding of their bodies and sexuality, thereby reducing stigma and fostering a positive self-concept. In contrast, restrictive and stigmatizing environments tend to worsen self-image and may contribute to anxiety and depression.
Pengaruh Pemberian Aromaterapi Jahe Terhadap Mual Muntah Pasca Operasi dengan Teknik Spinal Anestesi di RS PKU Muhammadiyah Gamping Rayyan Rahma Dwi Putri Paputungan; Joko Murdiyanto; Istiqomah Rosidah
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3126

Abstract

Nausea and vomiting are common side effects following spinal anesthesia and surgery. If postoperative nausea and vomiting (PONV) are not managed, they can lead to dehydration, electrolyte imbalance, wound dehiscence, and rupture. Efforts to manage nausea and vomiting include pharmacological and non-pharmacological approaches. The use of ginger aromatherapy is a non-pharmacological method to alleviate postoperative nausea and vomiting. To determine the effect of ginger aromatherapy on postoperative nausea and vomiting in patients undergoing spinal anesthesia at PKU Muhammadiyah Gamping General Hospital. This study employed a pre-experimental design with a one-group pretest-posttest approach. The subjects were 57 postoperative patients who received spinal anesthesia, selected using purposive sampling. Nausea and vomiting responses were measured using the Gordon score.. Data analysis was performed using the Wilcoxon Signed Rank Test. The p-value was 0.000, indicating that the alternative hypothesis (Ha) was accepted and the null hypothesis (H0) was rejected. This means there is a significant effect of ginger aromatherapy on postoperative nausea and vomiting in patients undergoing spinal anesthesia at PKU Muhammadiyah Gamping Hospital.
Penetapan Kadar Hidrokuinon pada Krim Pemutih Wajah yang Beredar di Pasar 45 Kota Manado dengan Metode Spektrofotometri UV-VIS Rosadalima Mere Tuku; Rifani Hutami Supardi; Ahlan Sangkal
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3128

Abstract

Long-term use of hydroquinone compounds can reduce melanin production, causing the skin to lose its protective function against sunlight. Manufacturers promote products in various media to increase sales, in fact the prevalence of illegal cosmetics is increasing every year. The purpose of this study was to determine the levels of hydroquinone contained in various brands of facial whitening cream cosmetics circulating in the 45 Manado City markets. Quantitative testing using the UV-Vis spectrophotometry method. The results showed that 5 samples taken in the 45 Manado City markets contained hydroquinone with sample levels of (A) 0,0339% and (B) 0,0536%. So it can be concluded that 2 samples of facial whitening cream do not comply with BPOM Regulation Number 23 of 2019 concerning facial whitening cream cosmetic preparations.

Page 28 of 32 | Total Record : 320

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