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Adit Widodo Santoso
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Gedung A Lantai 5 Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana, Jl. Arjuna Utara No. 6, Duri Kepa, Kebon Jeruk, Jakarta Barat 11510
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Jurnal Kedokteran Meditek
Published by Universitas Kristen Krida Wacana
ISSN : 26861437     EISSN : 26860201     DOI : https://doi.org/10.36452/jkdoktmeditek
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Jurnal Kedokteran MEDITEK merupakan jurnal ilmiah yang mempublikasikan artikel-artikel dalam lingkup bidang kedokteran dan biomedik secara open access. Proses publikasi artikel melalui proses penelaahan oleh pakar sebidang (peer-review) secara double-blind. Jurnal Kedokteran Meditek berafiliasi pada Fakultas Kedokterandan Ilmu Kesehatan Universitas Kristen Krida Wacana, dengan misi mendorong penyebarluasan perkembangan ilmu kedokteran & biomedis di Indonesia maupun secara global dengan menerbitkan 3 edisi dalam setahun, yaitu: Januari, Mei dan September.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 648 Documents
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Non-motor Symptom Burden and Its Clinical Correlates in Parkinson’s Disease: A Cross-sectional Study in Indonesia Situmeang, Rocksy Fransisca V; Gabriella, Nadia
Jurnal Kedokteran Meditek Vol 32 No 4 (2026): JULI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i4.4204

Abstract

Introduction: Non-motor symptoms (NMS) are increasingly recognized to have disabling impact on the quality of life of idiopathic Parkinson’s disease (PD) patients, comparable to motor symptoms. However, their relationship with clinical and demographic factors remains obscure in local populations. Purpose: To determine the prevalence of NMS in idiopathic PD and evaluate their correlation with clinical variables, including disease duration, Hoehn & Yahr (H&Y) stage, and PD subtype. Methods: This cross-sectional study consecutively included idiopathic PD subjects evaluated between July-October 2025. Data collected included age, gender, age at onset, disease duration, H&Y stage, and PD subtype. NMS were assessed using the Indonesian version of Non-Motor Symptoms Questionnaire (NMS-Q). Correlation and multiple linear regression analyses performed. Results: Fifty-three subjects were included (mean age 66.9±10.5 years; 50.9% male). Median disease duration was 5 years (IQR 1–7.5), with majority in H&Y stage 2 (49%). Mean total NMS-Q score was 10.7±5.2. The most frequent NMS was urinary urgency (66%), with urinary domain being the most affected (64.2%). Total NMS-Q scores correlated with H&Y stage (r=0.427, p=0.001) and disease duration (r=0.309, p=0.025). Only H&Y stage independently predicted total NMS-Q scores (B=2.657, p=0.010). Conclusion: This study provides additional evidence from an Indonesian population using a standardized assessment tool, demonstrating that disease severity is an independent predictor of NMS burden, thus highlighting the importance of early and systematic evaluation of NMS in idiopathic PD.
Korelasi antara Tipe Kepribadian dan Tingkat Burnout pada Mahasiswa Kedokteran Universitas Negeri di Jakarta Selatan Alvina, Alvina; Pramariza, Zalfa Kaila
Jurnal Kedokteran Meditek Vol 32 No 4 (2026): JULI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i4.4248

Abstract

Introduction: Medical students are at high risk of burnout due to academic demands and psychological stress during their studies. Burnout can impact mental health, academic performance, and professional preparedness. Personality types are considered potential factors influencing vulnerability to burnout. Purpose: To examine the relationship between personality type and burnout levels among medical students.  Methods: A quantitative cross-sectional study was conducted involving 136 medical students. Personality types were assessed using the Big Five Inventory-2 Short Form (BFI-2-S), while burnout was measured with the Maslach Burnout Inventory-Student Survey (MBI-SS). Data were analyzed using Spearman correlation test. Results: Most respondents were categorized as moderate across all personality dimensions, and 86.8% experienced high burnout. Significant correlations were found between all personality dimensions and burnout. Neuroticism showed a positive correlation (r = 0.357; p < 0.001), whereas extraversion (r = -0.295; p < 0.001), agreeableness (r = -0.259; p = 0.002), conscientiousness (r = -0.339; p < 0.001), and openness (r = -0,304; p < 0.001) showed negative correlations. Conclusion: Big Five personality types are associated with burnout among medical students. Neuroticism relates to higher burnout levels, while other dimensions are associated with lower burnout levels.
Fabrikasi dan Karakterisasi Membran Selulosa Bakteri-Kolagen dengan Metode Freeze Dryingsebagai Kandidat Dural Graft Paramadini, Adanti Wido; Kurniawati, Ajeng Dyah; Faizah; Wijaya, Rheynaldi; Dermawan, Muhammad Saldi
Jurnal Kedokteran Meditek Vol 32 No 4 (2026): JULI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i4.4336

Abstract

Introduction: The dura mater protects the brain, maintains tissue stability, and prevents cerebrospinal fluid leakage. Dural defects from trauma, tumors, or neurosurgery often require duraplasty using a dural graft. Current materials—autologous, allogeneic, and synthetic—have limitations including infection risk, adhesion, immune reactions, and limited availability, prompting exploration of alternative materials. Bacterial cellulose offers high biocompatibility and a nanofibrillar structure resembling the extracellular matrix, while collagen enhances material bioactivity. Objective: This study evaluated bacterial cellulose-collagen biocomposites as candidate dural implants using FTIR and swelling tests. Methods: Bacterial cellulose was synthesized using Acetobacter xylinum in coconut water medium and freeze-dried for 48 hours. Biocomposites were prepared by immersing cellulose pellicles in collagen solutions at 0% (control), 0.5%, 1%, and 1.5% (w/v), dried at room temperature, and characterized by FTIR and swelling analysis. Results: Collagen incorporation altered the chemical structure, shown by increased O–H groups and a wavenumber shift with eventual disappearance of the C–H group as collagen concentration rose. Swelling ratio increased across all collagen-containing samples, indicating interactions that may modify the material's physical properties. Conclusion: Collagen addition improved the structural and swelling characteristics of the biocomposites, supporting their potential as artificial dura mater material, pending further evaluation of mechanical properties and biocompatibility.
Pemahaman Anatomi Klinis Dalam Praktik Klinis Peserta PPDS Kedokteran Fisik Dan Rehabilitasi Di FKUI Sudiyono, Nelson; Steffany, Jocelyne Aurelia; Uinarni, Herlina; Marwisitaningrum, Florentina; Sasmita, Poppy Kristina; Djuartina, Tena; Irawan, Robi
Jurnal Kedokteran Meditek Vol 32 No 5 (2026): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i5.4098

Abstract

Introduction: Anatomical knowledge is a fundamental foundation in the practice of Physical and Rehabilitation Medicine (PRM). Residents in the Physical and Rehabilitation Medicine residency program require a deeper understanding of anatomy to establish diagnoses, provide comprehensive management, and accurately evaluate therapeutic outcomes in patients with physical and cognitive disabilities. However, many residents experience difficulties in learning anatomy due to limited study time, restricted access to cadavers, and a lack of innovation in learning methods. Purpose: To explore the level of clinical anatomical understanding, learning approaches, and clinical practice experiences among PRM residents as a basis for developing more effective learning strategies. Methods: A descriptive study involving 59 PRM residents at the Faculty of Medicine, Universitas Indonesia. Data were collected through anatomy quizzes and electronic questionnaires. Results: A total of 52.5% of respondents demonstrated clinical anatomy understanding with scores above the mean (66.32). Clinical-based learning methods were used by 42.4% of respondents, while 64.4% used integrative learning media. Additionally, 98.3% of respondents applied anatomical knowledge in daily physical examinations. Conclusion: Most respondents demonstrated a fairly good level of anatomical understanding, as reflected in their consistent application of anatomical knowledge in daily clinical practice. Nevertheless, there remains an opportunity to further enhance competence through continuous professional development, particularly in the field of clinical anatomy.
Estimasi Interval Post-Mortem Berdasarkan Laju Dekomposisi Jaringan di Berbagai Segmen Sungai Ciliwung Alifia, Shakira Nurlaili; Yen, Liauw Djai; Winata, Handy; Purnamawati, Purnamawati
Jurnal Kedokteran Meditek Vol 32 No 5 (2026): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i5.4157

Abstract

Introduction: The Ciliwung River is frequently reported as a location of drowning cases in Indonesia. Variations in aquatic environmental conditions along the river are presumed to influence the rate of postmortem tissue decomposition, which plays an important role in postmortem interval estimation in forensic investigations. However, empirical data regarding tissue decomposition rates in tropical aquatic environments remain limited. Purpose: This study aimed to determine and compare the decomposition rate of beef as a postmortem decay model in the upstream, midstream, and downstream segments of the Ciliwung River. Methods: This descriptive experimental study used 30 beef samples measuring 2×2×2 centimeters with an initial weight of 9.3 grams. The samples were divided into six groups, consisting of two control groups and four treatment groups based on water sources from different segments of the Ciliwung River. Observations were conducted over a 10-day period at 24-hour intervals, assessing changes in color, odor, texture, and mass. Water microbiological analysis was performed using the Most Probable Number method to determine fecal coliform and total coliform levels. Results: The fastest decomposition rates were observed in the second midstream and downstream segments, whereas the upstream segment exhibited the slowest decomposition. Higher coliform levels were correlated with accelerated decomposition. Conclusion: Decomposition rates differed among segments of the Ciliwung River and were influenced by aquatic microbiological conditions. This study provides preliminary data to support postmortem interval estimation in forensic investigations within tropical aquatic environments.
Studi Pilot Kesukaan Mahasiswa Kedokteran dan Kedokteran Gigi Tahun Pertama terhadap Ilustrasi Untuk Belajar Biomedis: Obyek Jantung Adrianto, Hebert; Silitonga, Hanna Tabita Hasianna; Asaeli, Agrippine Putricia; Sanjaya, Maria Laurentia; Mulyawan, Tara M; Sari, Uti Nilam; Mulyadi, Abdurrahim
Jurnal Kedokteran Meditek Vol 32 No 5 (2026): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i5.4209

Abstract

Introduction: Presenting appropriate illustrations in biomedical learning can determine enthusiasm for learning, increase understanding of concepts, and support independent learning. Purpose: This study aims to identify students' preferences for illustrations for learning biomedical science, specifically using the cor as the object. Methods: The study employed a qualitative approach through research and development (R&D), including the development of medical illustrations with professional illustrators and assessment. Ten students from the Faculty of Medicine and ten from the Faculty of Dentistry, class of 2024, at Ciputra University Surabaya, were given two modules. After reading the modules, respondents completed questionnaires. Data were analyzed descriptively and through a general inductive approach. Module A used illustrations from a commercial textbook, while Module B used step-by-step illustrations designed by the researchers. The questionnaire data were analyzed descriptively and content analysis. Results: All respondents (100%) preferred module B. Most respondents (85%) preferred module B as a self-study medium compared to module A. General inductive analysis revealed consistent patterns regarding the characteristics of illustrations that were thought to help students learn biomedicine independently, namely 1) clear and attractive colors, 2) gradual illustrations, 3) clear and concise captions, 4) large and proportional illustration sizes, 5) blood flow marking, 6) illustration layout, 7) real images/3D shapes, and 8) integration of anatomy and physiology. Conclusion: The results of this study showed that respondents  preferred module B. This finding suggests that students do not need a single scientifically accurate illustration but several illustrations designed to reduce cognitive load and facilitate the gradual process of knowledge construction.
Hubungan Usia dan Lama Hipertensi dengan Kompleksitas Pembuluh Darah pada Penyakit Arteri Perifer Ekstremitas Bawah Hendrik Mark Jack Tampi; Alexander Jayadi Utama; Raden Suhartono
Jurnal Kedokteran Meditek Vol 32 No 5 (2026): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i5.4369

Abstract

Introduction: Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis common in elderly and hypertensive patients. Anatomical lesion complexity is assessed using the Global Limb Anatomic Staging System (GLASS), yet its association with age and hypertension duration remains understudied, particularly in Indonesia. This study aimed to assess the association of age and duration of hypertension with vascular anatomical complexity based on the GLASS classification in hypertensive PAD patients. Methods: This cross-sectional analytical observational study used medical record data from hypertensive PAD patients who underwent computed tomography angiography (CTA). Bivariate analysis used the One-Way ANOVA and Kruskal-Wallis tests, while multivariate analysis used ordinal logistic regression. Results: A total of 97 patients met the inclusion and exclusion criteria. The mean age was 64.65 ± 11.17 years, and the median duration of hypertension was 5 years (range: 1–35 years). GLASS stage distribution was dominated by stage III (43.3%), followed by stage II (41.2%) and stage I (14.4%). Age was not significantly associated with GLASS stage in bivariate analysis (p = 0.776), whereas duration of hypertension was (p = 0.044). In multivariate analysis, neither age nor duration of hypertension was significantly associated with GLASS stage (p > 0.05). Anatomical complexity in PAD cannot be predicted from age or hypertension duration alone, so revascularization still requires comprehensive GLASS evaluation. Conclusion: Age was not associated with lesion complexity as defined by GLASS, while hypertension duration showed a significant bivariate association not confirmed on multivariate analysis.
Hubungan POBA dan Stent dengan Restenosis Enam Bulan pada Lesi Femoropopliteal dan Infrapopliteal Berdasarkan GLASS April Hidayat; R. Suhartono; Wawan Mulyawan
Jurnal Kedokteran Meditek Vol 32 No 5 (2026): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i5.4381

Abstract

Introduction Peripheral arterial disease (PAD) is a systemic atherosclerotic condition that frequently requires endovascular revascularization. Post-angioplasty restenosis remains a major clinical challenge affecting mid-term outcomes. This study analyzed the association between the use of plain old balloon angioplasty (POBA) and stenting and 6-month restenosis in femoropopliteal and infrapopliteal lesions according to the GLASS classification. Methods: An analytical observational study with a retrospective cohort design was conducted using medical records of PAD patients who underwent angioplasty at RSCM between January 2019 and March 2026. A total of 243 patients met the inclusion criteria. Data were analyzed using the chi-square test or Fisher's exact test, applied according to which assumptions were met. Results: Restenosis occurred in 94 patients (38.7%). Age was significantly associated with restenosis (p=0.002), and lesion location was also significant (p=0.001), with restenosis occurring more frequently in infrapopliteal lesions. POBA use, stent use, and the total GLASS score were not significantly associated with restenosis (p=0.306, p=0.306, and p=0.929, respectively). In the location-stratified analysis, both the GLASS score and POBA use showed significant associations with restenosis (p=0.01), whereas stent use according to lesion location showed no significant association (p=1.00). Conclusions: In PAD patients undergoing angioplasty, lesion location and age are the dominant determinants of restenosis, outweighing procedural modality choice between POBA and stent placement.

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