cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Viskasari P. Kalanjati
Contact Email
fmi@journal.unair.ac.id
Phone
-
Journal Mail Official
fmi@journal.unair.ac.id
Editorial Address
Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
Location
Kota surabaya,
Jawa timur
INDONESIA
Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 571 Documents
 10   11   12   13   14 
Molecular Genotyping of Tsst-1 Gene Staphylococcus Aureus from Clinical Specimen Puspitarini, Marinda Dwi; Setyarini, Wahyu; Hadi, Usman; Kuntaman, Kuntaman
Folia Medica Indonesiana Vol. 57, No. 2
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Staphylococcus aureus (S. aureus) is the most common pathogen in humans that causes various infections. Variations in infections due to S. aureus are related to the presence of virulence factors, one of which is Toxic Shock Syndrome Toxin-1 (TSST-1) which is the main cause of Toxic Shock Syndrome (TSS). This study aimed to explore the genetic pattern of the tsst-1 genes among MSSA and MRSA from clinical isolates of patients at Dr. Soetomo Academic Hospital, Surabaya-Indonesia. PCR examination was performed on 106 clinical samples of S. aureus isolates to determine the presence of the tsst-1 genes; subsequently, phylogenetic analysis was performed. The positive tsst-1 genes were found in 3 (5.7%) MSSA isolates and 2 (3.8%) MRSA isolates from 106 samples, of which were divided into 53 MSSA isolates and 53 MRSA isolates. No significant difference was noticed between the tsst-1 genes on both the MSSA and MRSA bacteria (p = 0.648). The positive tsst-1 genes were found in 1 (4.5%) of pus specimens and 2 (16.7%) of blood specimens from MSSA isolates. However, the positive tsst-1 genes were found in neither sputum nor urine specimens. The genes were found in 2 (16.7%) of blood specimens from MRSA isolates. Based on the phylogenetic tree, Indonesian tsst-1 isolates belonged to the same clade as Japan, Iran, Iraq, India, Egypt and the United Kingdom isolates. The prevalence of tsst-1 genes of both MSSA and MRSA from clinical isolates in Dr. Soetomo Academic Hospital Surabaya are 5.7% and 3.8%, respectively. The tsst-1 genes of Surabaya-Indonesia, Japan, Iran, Iraq, India, Egypt and the United Kingdom belonged to the same clade.
Case report: endovascular stenting in peripheral arterial disease of lower extremity Oktaviono, Yudi Her
Folia Medica Indonesiana Vol. 52, No. 2
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Peripheral arterial disease (PAD) is usually caused by multilevel atherosclerotic disease, typically in patients with a history of cigarette smoking, diabetes mellitus, or both. Intermittent claudication (IC), an early manifestation of PAD, commonly leads to reduced quality of life for patients who are limited in their ambulation. Percutaneous intervention for peripheral artery disease has evolved from balloon angioplasty for simple focal lesions to multimodality techniques that enable treatment of severe arterial insufficiency. Especially for high-grade stenoses or short arterial occlusions, percutaneous transluminal angioplasty (PTA) should be the method of first choice followed by the best surgical procedure later on. To achieve good long-term efficacy, a close follow-up including objective tests of both the arterial lesion and hemodynamic status, surveillance of secondary preventive measures and risk factor control is mandatory.
Profile of type ii diabetes mellitus with central obesity in dr. Soetomo hospital Munir, Misbakhul; Sutjahjo, Ari; Sustini, Florentina
Folia Medica Indonesiana Vol. 51, No. 3
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Obesity, especially central obesity is often associated with insulin resistance and type 2 diabetes mellitus. Diabetes mellitus is a disease of the number six cause of death in Indonesia with the proportion of deaths by 5.8%. The purpose of this study was to identify central obesity in patients with type 2 diabetes mellitus in Poly Endocrine Dr. Soetomo Hospital, Surabaya. The study design was descriptive study. The sample was 100 type 2 diabetes mellitus patients taken with purposive sampling technique. The variable was central obesity and type 2 diabetes mellitus. The data obtained by interviewing patients and performing measurements on body weight, height and waist circumference. Data were analyzed by interpreting how the description of the variables studied and compared with other studies and theories. The results was the characteristics of patients most were female (66%), level of education was medium, unemployment, most of patient's age was more than 50 years old, 43% for interval 51-60 years old, 43% were 1,50-1,59 meters in height and 28% were 50-59 kilograms and 28% were 60-69 kilograms in weight. According to Body Mass Index (BMI) measure that 54% the patients are normal in average 25,56 8,12 kg/m2. Measurement of waist circumference showed that 73.5% male and 81.8% female patients had central obesity. The conclusions, precentage of patients with type II diabetes mellitus who have central obesity were 81,82% female and 73, 53% male.
Analysis of deferasirox and deferipron use in children with pediatric -thalassemia major Sutrisnaningsih, Evy Sari; Suharjono, Suharjono; Sudarmanto, Bambang
Folia Medica Indonesiana Vol. 52, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

b-thalassemia major is a genetic disease and a decline in production due to imperfect of hemoglobin. Clinical manifestations are anemia, treated with regular blood transfusions. Blood transfusions lead to an increase in iron in the body that can lead to organ complications. Iron chelation drug delivery is expected to reduce complications due to an increase in the amount of iron in the body by measuring serum ferritin. The study aims to analyze the use of deferasirox and deferipron in patients with b-thalassemia major children at Dr. Kariadi Hospital of January 1, 2012 until December 31, 2013 as well as the need for blood transfusions. Patients who met the inclusion criteria, ie patients with b-thalassemia major children, retrospectively conducted observations of medical records include basic data and laboratory data. After descriptive analysis was performed to determine the use of two types of iron chelating drugs. In this study, 9 patients included in the inclusion criteria. A total of 5 people using deferasirox and 4 using deferipron at baseline. There are 3 people who turned deferipron be deferasirox. Serum ferritin values at study entry was> 1200 mcg/L, and at the end of the study serum ferritin is> 1200 mcg/L. The mean dose of deferasirox study was 19 ± 4.3 mg, and the dose deferipron mean was 80.8 ± 7.7 mg. Mean hemoglobin levels before transfusion was 6.60 ± 0.89 mg/dL. The average number of blood transfusions given was 336.52 ± 73.85 ml. Type of blood transfusion is used Washed erythrocyte. Splenomegaly occurred in 2 patients. There is no change in renal function, and hepatic meaning. The final conclusion until the reduction target serum ferritin <1000 mg/L has not been reached. Deferasirox dose can be increased to achieve the expected serum ferritin.
Purple Rosella (Hibiscus sabdariffa Linn.) Petal Extract Prevents Hepatocyte Degeneration in Wistar Rats Exposed to Cigarette Smoke Ulilalbab, Arya; Wiratmadi, Bambang; Adriani, Merryana
Folia Medica Indonesiana Vol. 54, No. 2
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Currently, the number of smokers in Indonesia is still high. Cigarette smoke contains free radicals. This study aimed to analyze the effects of purple rosella petal extract on the prevention of hepatocyte degeneration in Wistar rats exposed to cigarette smoke. Twenty male rats were divided into four groups: negative control, positive control, treatment group receiving 270 mg/kg BW purple rosella petal extract, and treatment group receiving 540 mg/kg BW purple rosella calyx extract. Negative control was only given with standard feed. Positive control was given with standard feed and exposed to 2 cigarettes a day. Treatment groups were fed with standard feed and administered with rosella extract in the morning then exposed to 2 cigarettes every day. This study was conducted for 28 days. At the end of the study, hepatocyte degeneration was observed in liver histopathology stained with hematoxilin eosin. The administration of purple rosella petal extracts in the doses of 540 mg/kgBW and 270 mg/kgBW significantly (p<0.05) prevented hepatocyte degeneration. Purple rosella petal extract is able to prevent hepatocyte degeneration in Wistar rats exposed to cigarette smoke.
Effects of lycopene on spermatozoa morphology in balb/c mice exposed to 2-methoxyethanol (2-me) Sitaresmi, Sandra Dewi; I'tishom, Reny; Mustika, Arifa
Folia Medica Indonesiana Vol. 53, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The compound of 2-methoxyethanol (2-ME) is one of toxic materials that potentially damage male reproductive organs. This compound can enter the body by various means of direct contact through the skin, respiratory and digestive tract. This compound can cause oxidative stress in spermatozoa which is the main cause of spermatozoa dysfunction. Lycopene, also known as red pigment, is an antioxidant class of carotene. Lycopene has antioxidant activity twice stronger than beta carotene and ten times stronger than vitamin E. Thus, the lycopene reaction as an antioxidant in the body is better than vitamin A, C, E, and other minerals. This study was conducted to determine the effects of lycopene on spermatozoa morphology in mice exposed to 2-ME. The study was conducted on 30 mice, divided into 5 groups. The K-group was the control group without 2-methoxyethanol and lycopene, the K + group was the group with 200 mg/kg BW 2-methoxyethanol on days 1-5, and the P1, P2 and P3 groups were the ones with 200 mg/kg BW 2-methoxyethanol on days 1-5 and lycopene doses of 5, 10 and 20 mg/kg BW on days 6-35. 2-ME was given intraperito-neally and lycopene was given per sonde. On day 36, the mice were sacrificed and the epididymis and vas deferens were removed for morphological examination of spermatozoa. The observations were performed using a microscope with 1000x magnification. The results showed that there was significant difference. In the morphology of spermatozoa, the administration of lycopene increases normal morphological percentage of spermatozoa in mice exposed to 2-ME.
Prevalence of Insomnia and Its Association with Social Media Usage among University Students in Selangor, Malaysia, 2018 Abdalqader, Mohammed A; Ariffin, Indang Ariati; Ghazi, Hasanain Faisal; AboBakr, Mohammed Faez; Fadzil, Mohd Ariff
Folia Medica Indonesiana Vol. 54, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Insomnia is an arising common health problem in Malaysia. There are many factors contributed to insomnia in young adults but very few are known. Increasing usage of social media may be one of the contributing factors to insomnia along its association with the sociodemographic factors. The objective of this study was to measure the prevalence of insomnia and to study its association with usage of social media and sociodemographic factors among university students. A cross-sectional based questionnaire was conducted among 445 students aged 18-30 years old in a private university in Selangor from July to August 2018. The questionnaire consisted of three parts to assess insomnia, social media usage and some socio-demographic factors. The age of the respondents ranged from 19 to 33 years old and the majority was relatable to insomnia (69%). The frequency of accessing social media was significantly associated with insomnia (p value=0.005). The time of the day of accessing social media mostly was significantly associated as well with insomnia, especially evening (p value=0.02), night time (p value=0.01) and before sleeping time (p value=0.04). The use of gadgets (phones/laptops/tablets) before sleeping at night also showed significant association with insomnia (p value=0.003). The sociodemographic factors (gender, age, race, income, relationship and living status) showed no significant association with insomnia. As a conclusion, the most influential factors that significantly associated to insomnia among students in a private university were the frequency of accessing social media, time of social media usage (the evening, night and before sleeping), and the usage of gadgets before sleeing on bed.
Correlation of Total IgE Level and Intensity of Infection among Soil Transmitted Helminthiasis Farmers in Klungkung Regency, Bali, Indonesia Apsari, Putu Indah Budi; Arwati, Heny; Dachlan, Yoes Prijatna
Folia Medica Indonesiana Vol. 55, No. 2
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The phenomena of increasing total IgE level in Soil Transmitted Helminthiasis and its protective role in resistance of infection remains unclear. The purpose of this study was to determine the correlation between total IgE and the intensity of Soil transmitted helminthiasis among farmers in these area. Total 162 farmer, age ranged 25-80 years participated in this cross sectional analytic study. Kato-Katz method was used to diagnose Soil Transmitted Helminthiasis and to determined infection intensity based on egg per gram (EPG). Total IgE levels were measured by enzyme linked flourescent assay (ELFA). The results of this study showed that 13,56% farmer positive for Soil Transmitted Helminthiasis, with single infection of Ascaris lumbricoides were 1,85%, 9,26% for Trichuris trichiura, 0,61% for Hookworm and mixed infection that were 1,23% for A.lumbricoides+T.trichiura 0,61% for A.lumbricoides+Hookworm. The intensity of infection were in mild category. Total IgE level in Soil transmitted Helminthiasis group was significantly different compared with noninfected group (p<0.05, t-test). There was significant correlation between EPG and total IgE level (r=0.667, p=0.001, Spearman test). As a conclusion total IgE level was significantly correlated with EPG, this fact can be used to develop management of Soil Transmitted Helminthiasis theraphy.
Congenital Parameatal Urethral Cyst in The Male: A Case Report and Review of Literature Oktaviani, Dian Paramita; Hoetama, Sakti; Soetojo, Soetojo
Folia Medica Indonesiana Vol. 56, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Purpose:: To report one case of parameatal urethral cyst. Background : Parameatal urethral cyst is a scarce congenital condition that was first reported in two males in 1956, until now in reported literature only found less than 50 cases, in both adults and children. Our patient, case of parameatal urethral cyst in a 5 years old boy is reported. Complete excision with total removal of the epithelium of the cyst is required management for the treatment and prevention of cyst reocurrance. Case Report:a 5 years old male with a cystic lesion around urethral meatus since birth. At least 5 month the parents complain distorted urinary flow and poor appearance, and no other urinary symptom, no history of trauma. On physical examination, cystic mass with spherical shape which was about 0.5 cm in diameter was found around external meatus. There was no inflammatory sign. And there was normal blood laboratory (blood counts and blood chemistry) and urine laboratory (urine analysis and urine culture). The patient undergo completely excision of the cyst under general anaesthesia, and remove all of the lining epithelium. Good appearance results were obtained after 2 months follow up, without meatal strictures and urine stream problems, and no postoperative complications or recurrence. Pathological : Squamous epithelial, granulation tissue with chronic inflamation. Conclusions :Parameatal urethral cyst is a very rare benign condition that is asymptomatic in most of the cases. It may be present since birth or appear later and is prevalent in young males. Its etiology remains unclear and treatment is by complete surgical excision to avoid complications and recurrence. Good cosmetic results were obtained in this case without any recurrence at two months follow up.Parameatal cyst, Glans penis, external meatus urethra, Urethral cyst
Differences of Indirect MAR Test in the Unexplained Infertile and Fertile Couples Ramadhona, Nur Hafiz; Hinting, Aucky; Lunardhi, Hamdani
Folia Medica Indonesiana Vol. 56, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Infertility is the inability of a partner to get pregnant after regular sexual intercourse without contraception for 12 months. Based on the cause, male infertility is caused by genetic, hormonal, infectious, sexual, and unexplained infertility. However, many infertile couples are classified into unexplained infertility without an antisperm antibody (ASA) immunological examination. This study aimed to prove that couples classified as unexplained infertility can be caused by ASA wives. This was an observational study with a cross sectional study design. The sample consisted of 2 groups, in which the first group consisted of 36 fertile couples and the second group consisted of 35 unexplained infertility couples. All samples were carried out indirect MAR test to obtain the ASA value of the wife. If the wife's ASA value was >40%, the ASA results were positive. Conversely, if the ASA value was <40%, the ASA results were negative. From these 2 groups, there was a statistically significant difference (p<0.0001) that the wife's ASA value in the unexplained infertility group was significantly higher than that in the fertile group. This study concluded that the positive ASA results from the indirect MAR test were significantly found in the unexplained infertility sample.

Page 12 of 58 | Total Record : 571

 10   11   12   13   14 

Filter by Year

2016 2025


Reset
Filter By Issues
All Issue Vol. 61, No. 2 Vol. 61, No. 1 Vol. 60, No. 4 Vol. 60, No. 3 Vol. 60, No. 2 Vol. 60, No. 1 Vol. 59, No. 4 Vol. 59, No. 3 Vol. 59, No. 2 Vol. 59, No. 1 Vol. 58, No. 4 Vol. 58, No. 3 Vol. 58, No. 2 Vol. 58, No. 1 Vol. 57, No. 4 Vol. 57, No. 3 Vol. 57, No. 2 Vol. 57, No. 1 Vol. 56, No. 4 Vol. 56, No. 3 Vol. 56, No. 2 Vol. 56, No. 1 Vol. 55, No. 4 Vol. 55, No. 3 Vol. 55, No. 2 Vol. 55, No. 1 Vol. 54, No. 4 Vol. 54, No. 3 Vol. 54, No. 2 Vol. 54, No. 1 Vol. 53, No. 4 Vol. 53, No. 3 Vol. 53, No. 2 Vol. 53, No. 1 Vol. 52, No. 4 Vol. 52, No. 3 Vol. 52, No. 2 Vol. 52, No. 1 Vol. 51, No. 4 Vol. 51, No. 3 More Issue