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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
Arjuna Subject : -
Articles 621 Documents
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Optimasi dan Formulasi Tablet Mengapung - Mucoadhesive Glimepirid dengan Kombinasi Polimer Karbopol dan HPMC K4M (Optimization and Formulation Floating - Mucoadhesive Glimepiride Tablet with Combination Carbopol and HPMC K4M) Hery Diar Febryanto; Lusia Oktora Ruma Kumala Sari; Eka Deddy Irawan
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Glimepiride is one of the preferred drug for the treatment of type II diabetes mellitus. Diabetes can affect gastric emptying time. Incomplete absorption of drugs often result in small bioavailability. Glimepiride was chosen as model drug because it has incomplete absorbtion due to less gastric residence time. Tablet make by direct compression using polymer carbopol, HPMC K4M and other additives. This study used factorial design. Factors that are optimazed are carbopol and HPMC K4M and responses used are floating lag time, floating duration time, mucoadhesive, dan DE 720. tablet were evaluated for invitro release characteristic for 12 hours. Area optimum obtained on the composition of the combination of Carbopol 69.20 to 70.60 mg and HPMC K4M 10.66 to 24.67 mg.   Keywords: glimepiride, floating mucoadhesive tablet, release kinetics, carbopol, HPMC K4M
Hubungan Jenjang Pendidikan terhadap Perilaku Menjaga Kesehatan Gigi dan Mulut Anak Tunagrahita di SLB Kota Sidoarjo Dianita Rahmah Julia; Ristya Widi Endah Yani; Roedy Budirahardjo
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.8661

Abstract

Intellectual disability is a child who suffers from intellectual ability below average and tends to have retardation in intelligence, physical, emotional, and social. They are not independent enough in keeping their own health especially oral hygiene, it can affect their oral health behavior. Education that is one of external factors influences health behavior. Education and knowledge influence each other so that people are expected to have high education in order to be knowledgeable especially in terms of maintaining health. The purpose of this study was to analyze the correlation between education level and oral health behavior of children suffering from intellectual disability. This research was an observational analytic research with cross sectional approach. The subjects of this study were a number of children of SDLB, SMPLB and SMALB in SLB Sidoarjo, with total sampling as many as 115 students. The subjects were asked to fill out a questionnaire of knowledge and attitude how to brush teeth and performed the action as well. The collected data were analyzed by using spearman correlation test. The result of this research showed that correlation coefficient for education level with knowledge, attitude and behavior was > 0,05, so there was no relation between those variables. Meanwhile, the result of correlation coefficient of education with action was < 0.05, so there was correlation between those two. The conclusion of this research is there is no correlation between the level of education and oral health behavior of intellectual disability children in SLB Sidoarjo. Keywords: Mental retarded, dental health behavior, education level
Uji Sitotoksisitas dan Proliferasi Senyawa 1-(4- Trifluorometilbenzoiloksimetil)-5-Fluorourasil terhadap Sel Kanker Payudara MCF-7 (Cytotoxicity and Proliferation Assay of 1-(4- Trifluoromethylbenzoyloxymethyl)-5-Fluorouracil) On MCF-7 Breast Cancer Cell Puspita Arum Wijayanti; Ayik Rosita Puspaningtyas; Dian Agung Pangaribowo
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

1-(4-trifluoromethylbenzoyloxymethyl)-5-fluorouracil (TFU) is a derivative compound of anticancer agent, 5-fluorouracil (5-FU). TFU has been synthesized by Ernawati to increase the anticancer activity of 5-FU. However, the cytotoxic and antiproliferative effect of TFU had not been carried out. This study aimed to evaluate the cytotoxic and antiproliferative activity of TFU compared to 5-FU on MCF-7 breast cancer cell line using MTT method. The citotoxicity study was done for 24 hours. The antiproliferative study was done for 24, 48, and 72 hours. The cytotoxic effect was determined based on IC50 value while the antiproliferative effect was determine based on the doubling time value. The results showed that TFU had better cytotoxicity on MCF-7 with IC50 value 401.03 ± 0.370 µM compared to 5-FU with IC50 value 4216.32 ± 800.28 µM. The doubling time value of TFU at concentration of ½ IC50, IC50, and 1½ IC50 were 359.66; 364.39; and 448.40 hours respectively, while 5-FU were 184.45; 214.00; and 220.63 hours. The doubling time value indicated that TFU compound was able to prolong the doubling time of MCF-7 cell line compared to 5-FU. Keywords: cancer, cytotoxicity, proliferation,1-(4-trifluoromethylbenzoyloxymethyl)-5-fluorouracil, MCF-7
Gambaran Status Kebersihan Rongga Mulut dan Status Gingiva Pasien RSGM Universitas Jember Oktober-November Tahun 2015 (The Description of Oral Hygiene Status and Gingival Status of Patients in Dental Hospital of Jemb Cici Widya Anggraini; Melok Aris Wahyukundari; Peni Pujiastuti
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background : Oral hygiene is very important to be kept for aestetic, phonetic,mastication function and health. There is a relationship between oral hygiene andgingival desease. Poor oral hygiene will increase the severity of gingival disease.However, some people still consider that oral hygiene issue is not something important.Purpose : To find out the status of oral hygiene and gingival status of patients in DentalHospital of Jember University and reviewed by age, gender and education. Metode :This study was a descriptive study with cross sectional approach. The samples were allnew patients of Dental Hospital of Jember University on October-November 2015. Theoral hygiene status was assessed by Oral Hygiene Index-Simplified (OHI-S) and gingivalstatus was assessed by Gingival Index (GI). Result : There were 35,84% of sample hada good oral hygiene, 54,87% had a medium oral hygiene and 9,29% had a poor oralhygiene. There were 7,08% of sample had a normal gingival, 58,85% had a light gingivalinflamation, 33,63% had a moderate gingival inflamation, and 0,44% had a severegingival inflamation.Keywords : Gingivitis, GI, OHI-S, Oral hygiene
Perpanjangan Waktu Perdarahan pada Pemberian Perasan Bawang Merah (Allium ascalonicum) (The Effect of Red Onion Juice (Allium ascalonicum) to Prolongation of Bleeding Time) Liliani Saputri Lijaya; Winny Adriatmoko; Zainul Cholid
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Bleeding is one of many deathscauses. In the dentistry, bleeding can be encountered such as post-surgery. Excessive bleeding may be caused by the consumption of drugs or certain foods. Red onion (Allium ascalonicum) is one of vegetables that isconsumed by people. It wasestimated to be able to affect bleeding because containedquercetinwhich effected on adhesion, aggregation, and platelet secretion. This study aimedto determine whether redonion juice couldcause prolongation of bleeding time in wistar rats. This study wasan experimental research laboratory. The researchsampleswere 28 wistar rats,divided into 4 groups. Samples were adapted for 1 week, then they were given the treatment each group, the group I was given distilled water, group II was given red onion juice 0,562 mg/g BB, group III was given red onion juice 1,125 mg/g BB, and the fourth group was given 2,25 mg/g BBred onion juice orally. Then we cut edge 1 cm long rat tail and every 30 seconds the blood that dripped out on absorbent paper until the bleeding stops, so we got the bleeding time in each sample. The results showed that there were significant differences between the four groups of samples. The conclusion of this study wasredonion juice couldcause prolongation of bleeding time in wistar rats, with the greatest prolongation of bleeding time at dosage of 2,25 mg/g BB, then the dosage of 1,125 mg/g BB, and the smallest at 0,562 mg/g BB of dosage. Keywords: bleeding time, platelet, quercetin, red onion
Mutu Pelayanan Voluntary Counseling and Testing (VCT) di Klinik VCT Puskesmas Puger dari Perspektif Provider Indah Ernawati; Christyana Sandra; Yennike Tri Herawati
Pustaka Kesehatan Vol 7 No 2 (2019): Volume 7 No. 2, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i2.19121

Abstract

Voluntary Counseling and Testing (VCT) is an entry point to help everyone in utilizing services related to HIV-AIDS prevention, care, support and treatment. Puger Primary Health Care is a primary health care located in the work area with the highest number of HIV-AIDS sufferers in Jember Regency, experiencing a decrease in client visits, and there are some management services that are still not in accordance with VCT guidelines. This study aimed to describe the quality of VCT services at the VCT Clinic Puger Primary Health Care from the perspective of provider. This study was descriptive study using questionnaire, documentation study, and observation. The study respondents were 7 VCT clinic officers. The results indicated that in input parameter showed a lack of human resources, insufficient funding, lack of availability and material conditions that meet the VCT guidelines. In planning indicators related to the human resources, improvements of infrastructure facilities had not been written in the POA, the job description was sufficient based on duties and competences of staff and there were coordination, supervision and evaluation. In the dimensions of technical competence, access to services, efficiency, human relations, continuity and safety of VCT clinics in good categories, but sufficient and less categories for dimensions of effectiveness and comfort dimensions.
Perbedaan Tingkat Kecenderungan Depresi pada Akseptor Berbagai Jenis Kontrasepsi Hormonal di Puskesmas Sumbersari Kabupaten Jember (The Difference of Depression Tendency Level on User of Several Hormonal Contraception Types in Sumbersari Primary Health Care, Jember) Ghuiranda S Ramadhan; Alif Mardijana; Hairuddin Hairuddin
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hormonal contraception is a method to prevent pregnancy that contains synthetic progesterone and estrogen. There are three types of hormonal contraception, i.e injection, pill, and implant. The side effect of hormonal contraception is depression. The aim of this research was to determine the difference of depression tendency level on several hormonal contraception types in Sumbersari Primary Health Care, Jember. This research method was analitical observational with cross sectional approache. Sample total were 103 hormonal contraception's acceptors who were recruited by proportionate stratified random sampling technique. Sample were interviewed using Hamilton Depression Rating Scale (HDRS) as the screening depression tendency level. Kruskal wallis statistical test showed significance point 0,00 (p<0,05). Post Hoc analysis with Mann-Whitney test between pill and injection acceptors group showed significance point 0,001 (p<0,05), 0,001 (p<0,05) for injection and implant acceptors group, then 0,000 (p<0,05) for pill and implant. In conclusion there is significance difference of depression tendency level in several types of hormonal contraception in Sumbersari Primary Health Care, Jember. Keywords: depression tendency level, hormonal contraception, HDRS
Perbandingan Komplikasi Malunion pada Pasien Fraktur Humerus Pasca Terapi Operatif dan Non-Operatif di RS Bina Sehat Djaya Mario Eri Surya Alfonsus; Muhamad Hasan; Erfan Efendi
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Humerus fracture is a quite common fracture. Fracture of diaphyseal humerus is 1,2 % of all cases of fracture. The treatment of humeral shaft fracture can use 2 different approaches, operative treatment and conservative treatment. This research aimed to compare the complication of malunion in patients with operative and conservative treatment. This was an observational analytic study on patients at the Bina Sehat Hospital. Samples were divided into 2 groups, operative and non-operative. Both groups were examined by measuring the lenght of the humerus after fracture comparing with its contralateral, the ability of the internal rotation, the ability of the external rotation, and angulation inspection. Statistical test showed a difference humerus shortening between 2 groups reached 0.873 cm. The difference between 2 groups on the ability of internal rotation reached 11.4710. The difference between 2 groups on ability of external rotation reached 16.608o. And the result for angulation assessment also showed significant difference between 2 groups. In conclutson, there was a significant difference in complications of malunion between operative and non-operative groups.   Keywords: humerus fracture, operative treatment, non operative treatment, comparative malunion
Pengembangan Sensor Kloramfenikol Berbasis Bovine Serum Albumin menggunakan Spektrofotometri UV (The Development of Chloramphenicol Sensor Based on Bovine Serum Albumin using Spectrophotometry UV) Sarah Aisha; Bambang Kuswandi; Dwi Koko Pratoko
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.6609

Abstract

Misuse of antibiotics has been discovered in shrimp exported from Indonesia, one of them is chloramphenicol, therefore it is necessary to develop methods for chloramphenicol detection. In this study, the chemical sensor for chloramphenicol detection has been developed. The sensor developed by immobilized bovine serum albumin (BSA) onto cellulose acetate membrane. The sensor has linear range of 6-16 μg/ml chloramphenicol with r 0.999 and limit of detection (LOD)-limit of quantification (LOQ) value of 0.74-2.21 μg/ml. The RSD value of repeatability and intermediet precision were 2.41% and 2.31%, where the recovery was 100.29%. Three of the five samples of tiger shrimp on the market containing chloramphenicol at level of 1.03; 2.48; and 3 μg/ml. The result also shown in good agreement with conventional spectrophotometry UV-Vis method. Keywords: shrimp, chloramphenicol, BSA, cellulose acetate
Kemampuan Membayar Iuran Jaminan Kesehatan Nasional Bagi Nelayan di Kabupaten Jember (Ability To Pay The Premium Of National Health Insurance For Fisherman in Jember) Widya Noormalasari; Nuryadi Nuryadi; Christyana Sandra
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

National Health Insurance is an Indonesian government program which mandates by social Insurance that required for all Indonesian citizens through BPJS. Coverage by independent participation in Jember is still very small that equal to 0.75 % of all participants registered. The results of a preliminary survey on the fisherman shows that 72.5 % of respondents thought unable to pay contribution JKN. The objective of this study was to calculate the ability to pay contribution of JKN for fishermen in Jember. This study was a quantitative descriptive study conducted in 3 villages, there are Puger Wetan village subdistrict Puger, Sumberejo village subdistrict Ambulu, and Lojejer village subdistrict Wuluhan. Results showed that most of respondents monthly income was middle which was in the interval ≥Rp.3.100.000,- to ≤Rp.7.750.000,- by the average was Rp.6.200.000,-; while the average household expenditure reached up to Rp.6.077.424,-. The calculation formula has got to calculate ability to pay is ΣRevenue – (-63880+ 0,8653X + ₁ 0,6361X3+ 1,277X4+ 1,081X5+ 0,6571X6+ 1,269X7+ 1,151X8+ 1,165X9+ 0,9445X10+ 1,307X11+ 1,540X12+ 0,9707X13+ 1,007X14+ 1,159X15+ 0.9988X16+ 1,047X17+ 1,064X18+ 3,517X19+ 1,015X20). Most of respondents (54,5%) were able to pay the premium of National Health Insurance. Most of respondents (61,11%) were only having ability to paid the premium for inpatient care grade 3 (Rp.25.500,- for one person every month). Keywords : Ability To Pay, National Health Insurance, Fisherman

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