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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
Arjuna Subject : -
Articles 621 Documents
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Analisis Efektivitas Biaya Penggunaan Antibiotik terhadap Pasien Sepsis di RSD dr. Soebandi TahunAnalisis Efektivitas Biaya Penggunaan 2014-2015 (Cost Effectiveness Analysis of Antibiotic Used for Sepsis Patients in dr. Soebandi Hospital During 2014-2015) Putri Kartika Ningsih; Prihwanto Budi Subagijo
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i1.5385

Abstract

Sepsis is a medical condition that is difficult to be identified and diagnosed. Sepsis often occurs to hospitalized patients in the hospital. Treatment with antibiotics is one of the factors supporting the success of sepsis treatment. The purpose of this study was to determine the most effective empirical antibiotics based on the cost effectiveness of adult and geriatric sepsis patients in RSD dr. Soebandi Jember during 2014-2015. This observational study was conducted by retrospective data collection. Data was collected from hospitalized sepsis patients medical records and received empirical antibiotics therapy at least three days. The parameters used in this study were costs which included the cost of accommodation, examination support, services, medicines, and medical devices, while the effectiveness used the length of stay, length of antibiotic related and the patients life expectancy. The results of incremental cost effectiveness ratio (ICER) showed that meropenem antibiotic had a lower cost Rp 378,808.07 compared to ceftazidime and cefotaxime. It can be concluded that meropenem antibiotic was more cost effective than ceftazidime and cefotaxime antibiotics. Keywords: cost effectiveness, pharmacoeconomic, antibiotic, sepsis
Preparasi dan Karakterisasi Nanopartikel Kitosan-Naringenin dengan Variasi Rasio Massa Kitosan-Natrium Tripolifosfat (Preparation and Caracterization of Naringenin-Chitosan Nanoparticles with Various Mass Ratio of Chitosan-Sodium Tripolyphosphat) Helmi Nur Laili; Lina Winarti; Lusia Oktora Ruma Kumala Sari
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Naringenin has a wide pharmacological activities. Low bioavailability of naringenin caused the under-developed utilization. Preparation of naringenin nanoparticles can improve the bioavailability. Chitosan as polymer for nanoparticles has ideal properties such as nontoxic, biocompatible, biodegradable. Sodium tripolyphosphat (NaTPP) used as an crosslinker to form nanoparticles by ionic gelation method. The aim of this research is to know the optimum formula of chitosan and NaTPP in naringenin-chitosan nanoparticles based on entrapment efficiency (EE) using factorial design. In this research, naringenin-chitosan nanoparticles were prepared with various mass ratio, 6:1, 10:1, 3:1, 5:1 and then EE each formulas measured by UV spectrophotometer. The optimum formula of naringenin-chitosan nanoparticles were characterized by PSA, TEM, and FTIR. The optimum formula (3:1) showed EE >42.12%. The consentration of chitosan and NaTPP to get final optimum formula were 0.06-0.0606777% for chitosan and 0.0970833-0.1% for NaTPP. The result of characterizations showed that size of naringenin-chitosan nanoparticles 13.2 ± 2.6 nm, PDI 0.443, zeta potensial 15.23 mV, complex chitosan-TPP formed. The results demostrated naringenin nanoparticles have successfully prepared. Keywords: naringenin, nanoparticle, chitosan, sodium tripolyphosphat
Efek Ekstrak Kulit Mangga Arumanis terhadap Penurunan Edema Kaki Mencit Putih Jantan yang Diinduksi Karagenin Ongky Dyah Anggraini; Cicih Komariah; Aris Prasetyo
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7666

Abstract

Mango is a plant contains many active compounds with health benefits. Total phenolic content of mango peel is higher than mango flesh, with its major component are mangiferin and quercetin. Quercetin has anti-inflammatory effects through the inhibition of inflammatory mediators are serotonin, bradykinin, histamine and prostaglandin, possibly could reduce oedema as a sign of inflammation. This study used carrageenin to induce inflammation by making paw oedema in mice. The aim of this research was to know the effect of arumanis mango peel extract to reduce paw oedema in white male mice. The was quasi experimental study with 7 study groups. Spearman analyses showed a correlation with significance of (p= 0.003) that mean it has a significant correlation (p <0.01) at the 330th min. Spearman correlation coefficients was 0,632, indicated that the dose of extract and paw oedema have strong correlation. It can be concluded that mango peel extract has effect for reducing paw oedema in white male mice, with the smallest dose was 1,002mg / gBW. Keywords: mango, quercetin, paw oedema
Kesiapan dan Persepsi Masyarakat Kabupaten Bondowoso terhadap Kebijakan Jaminan Kesehatan Nasional (JKN) (Preparedness and Perception of Bondowoso Community for National Health Insurance) Eri Witcahyo
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Bondowoso is districts in East Java with the third lowest HDI, which amounted to 65.39 with a lifeexpectancy of 63.95 years. It shows that access to health is still limited. According to theseconditions, it needs for a review the implementation of the National Health Insurance policy. Theobjective of this study was to analyze the preparedness and perception of Bondowosocommunity for the National Health Insurance (NHI) policy. This type of research is observationaldescriptive with quantitative approach. The sample was 192 respondents with multistage randomsampling technique. Data was obtained through interviews using a questionnaire, and thenanalyzed using univariate and presented descriptively. Research shows that respondents aged40-49 years (39.1%), male sex (68.8%) with a high school education level / equivalent (55.2%).Resources owned television (97.4%). However, respondents get information NHI fromneighbors / friends (54.1%), respondents felt the need to have health insurance for families(65.6%). There were 58.3% of respondents who were not participants NHI the groundscomplexity procedures (46.4%). Income and expenditure of respondents in the range of1,000,000 to 2,000,000 rupiah. NHI amounts of fees that could be accepted by the response was5,000 rupiah (31.8%).Keywords: preparedness, perception, national health insurance
Perubahan Tanda Vital sebagai Gejala Rasa Cemas sebelum Melakukan Tindakan Pencabutan Gigi pada Mahasiswa Profesi Klinik Bedah Mulut RSGM Universitas Jember (The Alteration of Vital Sign as Students’ Anxiety Symptoms before Performing Tooth Extraction in Farrahdina Nuri Arini; Winny Adriatmoko; Masniari Novita
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background:: First extraction performed by students of the oral surgery department givemany pressure causing body's responses such as increasing of blood pressure, pulserate, and respiratory rate. In severe rate, the outcome of the treatment may be affected bythis condition. The aim of the study to determine the alteration of vital sign as students’anxiety syndroms before performing tooth extraction in dental surgery department.Methods : This was a descriptive study of students of oral surgery department who willperform first tooth extraction. After sign an informed consent then performed themeasurement of blood pressure, pulse, and respiratory rate for 5 times, before the dayperforming extraction, before performing the examination on patient, before performinganesthesia, before performing extraction, and after performing the extraction. Result andconclusion : Students of the oral surgery department Dentistry University of Jembershowed increasing the vital sign status (blood pressure, pulse, and respiratory rate)before performing first tooth extractionKeywords : Tooth extraction, anxiety, vital sign, oral surgery.
Hubungan Kepemimpinan dan Motivasi Kerja Pegawai dengan Kinerja Puskesmas di Kabupaten Jember (The Correlation between Leadership and Employee’s Work Motivation with Working Performance of Public Health Center in Jember) Reni Chairunnisah; Nuryadi Nuryadi; Eri Witcahyo
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

The working performance of Public Health Center (PHC) is very essential in health development efforts. The working performances of PHC in 2012 is recorded from 89,7 to 144,20 and in 2013 is from 110,02 to 156,14. These values are far below the standard of 199. This shows that there is a problem of low working performance of PHC in Jember. This study aims to analyze the correlation between leadership and employee motivation to the working performance of PHC in Jember. The study is an analytical research with quantitative design. The number of sample was 316 respondent. The data were analyzed by using the Spearman rank correlation test. The result of the study showed that the leadership is in the category of good and very good leadership (89,9%), employees work motivation is in the medium category (63%) and it also showed that the performance of PHC in Jember is in the medium category. The analysis results indicate that there is a correlation between leadership and the working performance of PHC (0,049
Studi Penggunaan Obat pada Pasien Osteoartritis Usia Lanjut di Instalasi Rawat Jalan Rumah Sakit dr. H Koesnadi Bondowoso Tahun 2013 Ema Rachmawati; Putu Setia Pratama; Afifah Machlaurin
Pustaka Kesehatan Vol 6 No 3 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i3.9868

Abstract

Osteoarthritis (OA) is a degenerative bone disease that begin by loss of articulary cartilage (joint). The disease most commonly affects the elder or adult people. Elderly people experiencing degenerative processes in which decreasing organ function. The organ degeneration causes several diseases resulting the patients to receive multi drug for the treatment and causing polypharmacy, thus will increase the risk of drug interactions. This study was conducted to determine the treatment for osteoarthritis and drug interactions that occur in patients with osteoarthritis. The method used was total sampling using the descriptive-retrospective approach. The sample was elderly osteoarthritis patients in outpatient installation which were treated in RSD dr. H Koesnadi Bondowoso during January to December 2013. In this study we found that the main treatment for osteoarthritis was non steroidal anti inflammatory drug (NSAID) that use to relief pain. From 108 samples of elderly osteoarthritis patients, we found that 17 patients (15.74%) indicating the potential for drug interactions. Keywords: osteoarthritis, outpatient age above 60 years, NSAID, drug interaction
Optimasi Hydroxypropyl Methylcellulose dan Xanthan Gum pada Tablet Floating-Mucoadhesive Gliclazide Metode Desain Faktorial (Optimization of Hydroxypropyl Methylcellulose and Xanthan Gum on Floating-Mucoadhesive Gliclazide Tablet using Factorial Design) Eva Setyorini; Eka Deddy Irawan; Lusia Oktora Ruma Kumala Sari
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Gliclazide is one of the drugs used for type 2 diabetes mellitus treatment. It requires frequent dosing which is why gliclazide need to be formulated into preparations using a controlled release drug delivery system. This study aimed to determine the optimum composition of hydroxypropyil methylcellulose (HPMC K4M) and xanthan gum polymer combination for gliclazide tablet. Tablets that have been produced were evaluated for tablets physical characterization, homogenity test, dissolution test, floating lag time, and mucoadhesive test. Tablets were optimized using a factorial design and the data were analyzed using design expert trial 9.0.6. The results showed that the optimal formulation for polymer combination in gliclazide tablet was 122.267-140.000 mg for HPMC K4M and 80.659-90.000 mg for xanthan gum.   Keywords: gliclazide, HPMC K4M, xanthan gum, floating-mucoadhesive system, factorial design.
Pengaruh Pemberian Monosodium Glutamat pada Induk terhadap Fase Erupsi Gigi Anak Tikus Wistar (Rattus norvegicus) Generasi Pertama (The Effect of Monosodium Glutamate Administration on Mothers Rat (Rattus norvegicus) to the Tooth Eruption Phase of the Fir Mindiya .; Didin Erma Indahyani; Pujiana Endahl Lestari
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Monosodium glutamat (MSG) is a kind of food additives which consumes widely in society. It may damage the hypothalamic arcuate nucleus and disturb the endocrin regulation system. This condition may delay the tooth eruption phase. Aim: To analyze the effect of MSG administration on the neonatal rats tooth eruption phase, whose mothers were given MSG during gestational period also during gestational and lactation period, to determine the difference between neonatal male and female tooth eruption phase. Materials and Methods: The first molar of right mandibular of neonatal rats from the control group (K1), the treatment group which mothers were given MSG during pregnant period (K2) and the mothers which were given MSG during pregnant and lactation period (K3) were collected as samples. The samples were examined by periapical rontgent to observe the tooth eruption phase. The result was measured by Corel Draw X3. Results and Conclusion: The tooth eruption phase in the treatment group (K2 and K3) are slower than the control group (K1), and there is no difference between neonatal male and female tooth eruption phase. Kata Kunci: hypothalamic arcuate nucleus, monosodium glutamate, tooth eruption
Hubungan Pemakaian Alat Pelindung Diri dengan Tingkat Kecacatan Klien Kusta di Wilayah Kerja Puskesmas Jenggawah dan Tempurejo Kabupaten Jember Tahun 2014 (The Correlation of Application Universal Precaution for Prevent Degree of Disability Clients Lepro Edho Choyrul Huzzein; Iis Rahmawati; Tantut Susanto
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Leprosy is chronic disease that caused by germs Mycobacterium leprae and could be caused problems relating to physical health that associated with a disability. Clients leprosy with disability can prevent with wearing universal precaution. The research done by observational analytic design. Design of collecting data was the level of disability and questionnare of users universal precaution. The respondent was only undergo treatment of MDT in the workplace of Jenggawah Health Centers and Tempurejo Health Centers who are 17 client leprosy. Based on research conducted that clients leprosy (35.3%) wear universal precaution and the clients leprosy (64.7%) not wear of universal precaution.Data analyzed with the technique of chi square correction. The result of a correction Fisher’s Exact test p value 0.010 show there was the relation of universal precaution with the level of disability clients leprosy. The results of research is expected to be the basis of promotion programs, prevention, and the aggrandizement of leprosy in Indonesia by integrating model intervention nursing of community and involving the related agencies. Keywords: Universal precaution, degree of disability, leprosy

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